Tropical Parasitology最新文献_第5页

Concomitant multiple subretinal cysticerci in neurocysticercosis. 脑囊虫病并发多发性视网膜下囊尾蚴。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_17_22

Simran Chhabra, Subina Narang, Anusuya Bhattacharyya, Ravinder Kaur

引用次数: 0

Prevalence of malaria: A 7-year trend analysis from a tertiary care center, Puducherry. 疟疾流行率：普杜切里三级护理中心的7年趋势分析。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_41_22

Rachana Kannambath, Nonika Rajkumari, Monika Sivaradjy

{"title":"Prevalence of malaria: A 7-year trend analysis from a tertiary care center, Puducherry.","authors":"Rachana Kannambath, Nonika Rajkumari, Monika Sivaradjy","doi":"10.4103/tp.tp_41_22","DOIUrl":"10.4103/tp.tp_41_22","url":null,"abstract":"Background: Battle against malaria has been going on since time immemorial. Understanding the true burden of disease and the determinants of its transmission are important for implementing adequate control measures. This study intends to explore the local epidemiology and burden of malaria in Puducherry, a coastal Union territory located in the Southern part of India over a period of 7 years.Methodology: A retrospective record-based study was conducted from 2015 to 2021, where details from all samples that tested positive for malaria by peripheral blood examination or rapid card test, from suspected cases were collected and analyzed.Results: The overall prevalence of malaria over the 7 years was 1.7% (257/14,888). Majority of the patients were male (75.88%) and the major age group affected was from 21 to 40 years (56.03%). The disease was maximum seen during the monsoon season followed by the post-monsoon season. Vivax malaria predominated irrespective of the gender, seasonal change, and different age groups except in children <10 years was both falciparum and vivax malaria were seen in equivalence. The major species to cause infection among infants were Plasmodium falciparum (3/4).Discussion and conclusion: This study shows a declining trend of malaria transmission over the years. There is no change in the predominant species affected or seasonal trends over the years. The possibility of underestimation of cases due to various factors cannot be ignored.","PeriodicalId":37825,"journal":{"name":"Tropical Parasitology","volume":"13 1","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9796627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular diagnosis and subtyping of Blastocystis sp.: Association with clinical, colonoscopic, and histopathological findings. 芽囊原虫的分子诊断和分型：与临床、结肠镜检查和组织病理学结果的相关性。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_28_22

Yasmine Amr Issa, Said Ahmed Ooda, Aziza Ibrahim Salem, Sahar Nasr Idris, Mona Mohammed Elderbawy, Mona Mohamed Tolba

{"title":"Molecular diagnosis and subtyping of Blastocystis sp.: Association with clinical, colonoscopic, and histopathological findings.","authors":"Yasmine Amr Issa, Said Ahmed Ooda, Aziza Ibrahim Salem, Sahar Nasr Idris, Mona Mohammed Elderbawy, Mona Mohamed Tolba","doi":"10.4103/tp.tp_28_22","DOIUrl":"10.4103/tp.tp_28_22","url":null,"abstract":"Introduction: Blastocystis sp. is the most common parasitic infestation in humans. However, its pathogenicity remains controversial. Our aim was to study the prevalence of Blastocystis sp. parasite subtypes in patients with gastrointestinal manifestations referred for colonoscopy and assess possible correlation with clinical, colonoscopic, and histopathological findings.Methodology: One hundred patients with gastrointestinal manifestations referred for colonoscopy were enrolled. Stool samples were collected and examined both microscopically and by real-time quantitative polymerase chain reaction (qPCR) for detection of Blastocystis sp. Subtyping was done for positive samples by qPCR and confirmed by sequencing.Results: qPCR sensitivity far exceeded microscopy in detection of Blastocystis sp. (58% vs. 31%, agreement 38.5%). The most commonly detected subtype was 3 (50%), followed by 2 (32.8%) and 4 (13.8%). Abdominal pain was the most common clinical symptom; inflammation and colitis were the most common abnormal colonoscopic and histopathological findings. The most frequent subtype encountered in those findings was Subtype 3.Conclusions: This study confirmed the importance of using qPCR in diagnosis of Blastocystis sp. An association between abnormal clinical, colonoscopic, and histopathological findings on the one hand, and Blastocystis sp. infestation, especially Subtype 3, on the other hand, is also posed. This necessitates further studies to assess the mechanism of association with pathogenicity.","PeriodicalId":37825,"journal":{"name":"Tropical Parasitology","volume":"13 1","pages":"46-53"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9806821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of histidine-rich protein 2 deletion among the Plasmodium falciparum isolates from Kolkata. 加尔各答恶性疟原虫分离株中富含组氨酸的蛋白2缺失的患病率。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_19_22

Alisha Acharya, Pabitra Saha, Abhijit Chaudhury, Subhasish Kamal Guha, Ardhendu Kumar Maji

{"title":"Prevalence of histidine-rich protein 2 deletion among the Plasmodium falciparum isolates from Kolkata.","authors":"Alisha Acharya, Pabitra Saha, Abhijit Chaudhury, Subhasish Kamal Guha, Ardhendu Kumar Maji","doi":"10.4103/tp.tp_19_22","DOIUrl":"10.4103/tp.tp_19_22","url":null,"abstract":"Context: Histidine-rich protein 2 (HRP2) detecting rapid diagnostic tests (RDTs) have played an important role in enabling prompt malaria diagnosis in remote locations. HRP2 has advantages over other biomarkers because of its abundance in the bloodstream, repetitive binding epitopes, and falciparum-specificity. Most HRP2-based RDTs also exhibit some cross-reactivity to a closely related protein (HRP3). Plasmodium falciparum parasites lacking HRP2 (pfhrp2) and 3 (pfhrp3) genes escape detection by these RDTs.Objectives: The objective of the study was to study the sensitivity and specificity of hrp2-based RDT for diagnosis of falciparum, to compare the RDT results with microscopy and polymerase chain reaction (PCR), and to determine the prevalence of HRP2 gene deletion among the RDT-negative, microscopy-positive falciparum strains.Materials and methods: Blood samples were collected and diagnosis was done by microscopic examination, RDTs, and PCR.Results: Out of 1000 patients examined, 138 were positive for P. falciparum. Fever was the most common symptom followed by chills with rigor and headache were recorded among more than >95% of the study patients. Three microscopy-confirmed P. falciparum cases were negative by HRP2-based RDT and were found to have deletion of HRP2 and HRP3 exon 2.Conclusions: Rapid and accurate diagnosis and prompt deployment of effective antimalarial medication are essential components of appropriate case management. P. falciparum strains that evade diagnosis by RDTs represent a major threat to malaria control and elimination efforts.","PeriodicalId":37825,"journal":{"name":"Tropical Parasitology","volume":"13 1","pages":"16-21"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9809264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review on cardiac manifestation of parasitic infection. 寄生虫感染的心脏表现综述。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_45_21

Animesh Mishra, Tony Ete, Vanlalmalsawmdawngliana Fanai, Amit Malviya

引用次数: 0

Ixodidae - A rare cause of blepharitis. Ixodidae——一种罕见的睑缘炎病因。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_92_21

C Alekhya, A R Rajalakshmi, Swathi Nagarajan

引用次数: 0

Clinical characteristics of malaria in COVID-19: A systematic review of case reports. 新冠肺炎疟疾的临床特征：病例报告的系统回顾。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_26_22

Chandana Rayella, Praveen Devanandan, Kavitha Rasuri, Sai Sudha Yerravelly, Sanjana Andem, Ranadheer Chowdary Puvvada

{"title":"Clinical characteristics of malaria in COVID-19: A systematic review of case reports.","authors":"Chandana Rayella, Praveen Devanandan, Kavitha Rasuri, Sai Sudha Yerravelly, Sanjana Andem, Ranadheer Chowdary Puvvada","doi":"10.4103/tp.tp_26_22","DOIUrl":"10.4103/tp.tp_26_22","url":null,"abstract":"Aims: Severe acute respiratory syndrome-coronavirus-2 is a viral infection that was first discovered in Wuhan, Hubei province, China, in December 2019. Effects of COVID-19 infection could drastically influence other concomitant diseases like Malaria. Malaria and COVID-19 may mimic each other and share look-alike symptoms. The aim of this systematic review was to analyze the clinical and biochemical characteristics of malaria and COVID-19 synergism that was based on the published case reports. Subjects and Methods: An extensive literature search was carried out between May 2020 and February 2022 in PubMed, Google Scholar, and EMBASE. Our study was devised according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Results: We have evaluated 16 case reports and one case series of coinfection of malaria with COVID-19. It has been observed that all the patients showed lymphopenia, fever, headache (52%), vomiting (47%), cough (38%), chills (38%), body ache (38%), myalgia (28%), and sweating (14%). Despite unprecedented times, whenever there is a suspicion, we recommend that medical practitioners should be alert to presenting plethora features of COVID-19 and confirm with polymerase chain reaction test. Conclusion: We conclude that screening for COVID-19 should also be performed to mitigate missed diagnoses due to the long incubation period of novel coronavirus. Especially in vulnerable population, we should suspect other concurrent diseases and diagnoses in patients presenting with the symptoms of COVID-19 infection.","PeriodicalId":37825,"journal":{"name":"Tropical Parasitology","volume":"13 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10164032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous seroprevalence of Toxoplasma gondii and rubella virus infections in pregnant women in Dakar (Senegal). 达喀尔（塞内加尔）孕妇弓形虫和风疹病毒感染的同时血清流行率。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_29_22

Mame Cheikh Seck, Papa A T Gueye, Pasca E Engo, Cheikh Faye, Moustapha Mbow, Khadim Diongue, Mamadou A Diallo, Mouhamadou Ndiaye, Aida S Badiane, Daouda Ndiaye

{"title":"Simultaneous seroprevalence of Toxoplasma gondii and rubella virus infections in pregnant women in Dakar (Senegal).","authors":"Mame Cheikh Seck, Papa A T Gueye, Pasca E Engo, Cheikh Faye, Moustapha Mbow, Khadim Diongue, Mamadou A Diallo, Mouhamadou Ndiaye, Aida S Badiane, Daouda Ndiaye","doi":"10.4103/tp.tp_29_22","DOIUrl":"10.4103/tp.tp_29_22","url":null,"abstract":"Context: Toxoplasma gondii and rubella virus are microorganisms that can cause intrauterine infections and congenital anomalies in the fetus. Data regarding the simultaneous seroprevalence of these infections are not available in Senegal.Aims: This study aimed to determine for the first time the simultaneous seroprevalence of toxoplasmosis and rubella among pregnant women in Dakar.Materials and methods: In this retrospective study, anti-Toxoplasma and anti-rubella antibodies were analyzed in the serum samples obtained from pregnant women receiving prenatal care at Military Hospital of Ouakam between 2016 and 2021 using a chemiluminescent microparticle immunoassay for the quantitative determination of immunoglobulin G (IgG) and IgM antibodies to Toxoplasma gondii and rubella in human serum.Results: Overall, data from 2589 women were analyzed. The median age was 29 years (interquartile range: 23.14-34.86). Serum IgG and IgM were positive for T. gondii with 35.84% and 1.66%, respectively. Rubella seroprevalence was 87.14% and 0.35%, respectively, for IgG and IgM. Seroprevalence of toxoplasmosis increases significantly with age and study period. For rubella infection, the highest seroprevalence rates were noted in the youngest age group and at the end of the study period.Conclusions: Data from this first-time study regarding simultaneous seroprevalence of toxoplasmosis and rubella among pregnant women in Senegal indicate a continuing high risk of congenital toxoplasmosis and congenital rubella syndrome in Dakar. Further studies are needed to fully assess the efficacy of rubella vaccination in women of childbearing age.","PeriodicalId":37825,"journal":{"name":"Tropical Parasitology","volume":"13 1","pages":"34-39"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9796629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proposed morbidity markers among Schistosoma mansoni patients. 曼氏血吸虫病患者的拟议发病率标志物。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_46_22

Amel Youssef Shehab, Amal Farahat Allam, Awad Abd El Kader Saad, Mervat Mostafa Osman, Heba Said Ibrahim, Esraa Abdelhamid Moneer, Mona Mohamed Tolba

{"title":"Proposed morbidity markers among Schistosoma mansoni patients.","authors":"Amel Youssef Shehab, Amal Farahat Allam, Awad Abd El Kader Saad, Mervat Mostafa Osman, Heba Said Ibrahim, Esraa Abdelhamid Moneer, Mona Mohamed Tolba","doi":"10.4103/tp.tp_46_22","DOIUrl":"10.4103/tp.tp_46_22","url":null,"abstract":"Background: Fecal calprotectin (FC) and fecal occult blood (FOB) were suggested as potential inflammatory markers for assessing intestinal schistosomiasis morbidity that are conventionally detected through invasive methods.Aim and objectives: The present work aimed to evaluate FC and FOB as morbidity markers of Schistosoma mansoni infection before and after praziquantel treatment.Materials and methods: A total of 205 stool samples (117 schoolchildren and 88 adults) were collected and examined by Kato Katz. A questionnaire enquiring about diarrhea, history of blood in stool, and abdominal pain was designed and applied.Results: S. mansoni prevalence rates were 20.5% and 11.36% among children and adults, respectively; the majority of cases had light infection intensity. FC and FOB were studied among 25 cured S. mansoni cases (17 children and 8 adults) pre and one-month post treatment. Before treatment, six and four children of moderate and high S. mansoni infection intensity tested positive for FC and FOB, respectively, all turning negative after treatment. FC showed borderline statistical significance before and after treatment among children. However, all adults tested negative for FC and FOB.Conclusion: FC and FOB could be possibly used as morbidity monitoring tools for S. mansoni infection in children with moderate and high infection intensity.","PeriodicalId":37825,"journal":{"name":"Tropical Parasitology","volume":"13 1","pages":"40-45"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9805766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An E-mail interview with Prof. Shyam Sundar. Shyam Sundar教授的电子邮件采访。

Tropical Parasitology Pub Date : 2023-01-01 Epub Date: 2023-05-19 DOI: 10.4103/tp.tp_13_23

引用次数: 0