Physics in Medicine最新文献_第3页

Evaluation of the usefulness of the Monte Carlo method for estimating the optimization of hemodialysis 评价蒙特卡罗方法对血液透析优化的有效性

Physics in Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.phmed.2021.100035

Agnieszka Gala-Błądzińska , Krystyna Tęcza , Wojciech Żyłka , Piotr Prach , Maciej Błądziński , Paweł Jakubczyk

{"title":"Evaluation of the usefulness of the Monte Carlo method for estimating the optimization of hemodialysis","authors":"Agnieszka Gala-Błądzińska , Krystyna Tęcza , Wojciech Żyłka , Piotr Prach , Maciej Błądziński , Paweł Jakubczyk","doi":"10.1016/j.phmed.2021.100035","DOIUrl":"10.1016/j.phmed.2021.100035","url":null,"abstract":"<div><p>Adequate hemodialysis minimizes complications and improves end-stage renal disease patient survival. Our study proposed a methodology for estimating hemodialysis parameters using two-compartment modelling together with Monte Carlo simulation of the probabilities of the model outputs. In addition, we modelled the removal of uremic toxins during hemodialysis, in comparison with the actual concentration of these toxins in the blood serum. Blood urea and phosphates were measured every 30 min throughout hemodialysis in 10 patients. Using a Monte Carlo simulation on the two-compartment model we estimated hemodialysis compatibility parameters for each patient individually. In patients with non-diabetic kidney disease, the actual urea and phosphate excretion dynamics were consistent with those predicted by the two-compartment model regardless of age, sex, non-diabetic comorbidities, duration of hemodialysis, residual diuresis, or type of vascular access. To measure compatibility, we used graph matching together with a quantitative measure given by a normalized coefficient of determination. In patients with end-stage diabetic kidney disease, the toxin elimination dynamics were significantly greater in the first 30 min of hemodialysis than in patients with non-diabetic kidney disease.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"12 ","pages":"Article 100035"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2021.100035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45839254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Theoretical basis for the hypothesis of white-matter resonance as a background of spike-wave discharges 白质共振作为突波放电背景假说的理论基础

Physics in Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.phmed.2020.100031

Shigeki Sadahiro

{"title":"Theoretical basis for the hypothesis of white-matter resonance as a background of spike-wave discharges","authors":"Shigeki Sadahiro","doi":"10.1016/j.phmed.2020.100031","DOIUrl":"10.1016/j.phmed.2020.100031","url":null,"abstract":"<div><p>It remains unclear how spike-wave discharges (SWDs) in electroencephalograms (EEGs) arise, although some researchers believe that there is some focus in the deep brain and others have pointed out the importance of the interaction between the thalami and cortices. My previous work hypothesized that possible resonance in white matter may induce extremely large amplitude discharges in an EEG, which are associated with SWDs. The visual evoked potential (VEP) technique revealed a resonance phenomenon that supports this hypothesis. In this research, I theoretically reconsidered the resonance phenomenon based on the cable theory modified by considering dielectric dispersion. If both the resistive and capacitive currents in the dielectric material contribute to conduction along an axon, we can show that the current amplitude has a single maximum at a certain frequency and this amplitude depends on the geometrical ratio of capacitance to resistance. The frequency can be common for any axon in a wide white-matter area. We can infer that SWDs will arise, when the frequency generated by the thalamic reticular nucleus neurons coincides with the resonance frequency of the white matter. The resonance frequency predicted by the modified theory is close to the known frequency of the SWDs.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"11 ","pages":"Article 100031"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2020.100031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42721001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Numerical prediction of the chemical indicator response used in steam sterilisers 蒸汽灭菌器中化学指示剂反应的数值预测

Physics in Medicine Pub Date : 2021-06-01 DOI: 10.1016/j.phmed.2020.100034

Paul Burian , Manuel Feurhuber , Marco Miranda , Marino Magno , Christoph Hochenauer

{"title":"Numerical prediction of the chemical indicator response used in steam sterilisers","authors":"Paul Burian , Manuel Feurhuber , Marco Miranda , Marino Magno , Christoph Hochenauer","doi":"10.1016/j.phmed.2020.100034","DOIUrl":"https://doi.org/10.1016/j.phmed.2020.100034","url":null,"abstract":"<div><p>Steam sterilisation is a commonly used method in the sterilisation of surgical instruments. To ensure the sterility of the sterilised goods an evaluation of the sterilisation process is required. This might be achieved either through physical measurements or indicators. Optimal sterilisation results are achieved by removing the air from the sterilisation chamber. In this paper a new computational fluid dynamics (CFD) based approach is presented, which allows to calculate the steam distribution within a sterilisation chamber with focusing on hollow loads. Additional measurements were performed using a self-developed measurement chamber to validate the CFD model. A modified process challenge device (PCD) with different tube lengths in combination with a chemical indicator (CI) was tested, to identify the volumetric influence of the lumen on the resulting air-steam mixture therein. A numerically efficient model was developed to determine a steam volume fraction threshold leading to a response of the CI. This study aims to predict the volumetric amount of steam which is necessary in order to pass a PCD test fitted with a CI. Both the CFD model and the measurements showed that often an insufficient steam penetration is indicated by PCDs which can lead to an insufficient sterilisation of hollow loads.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"11 ","pages":"Article 100034"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2020.100034","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136525991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

FDTD simulation study of ultrasonic wave propagation in human radius model generated from 3D HR-pQCT images 三维HR-pQCT图像生成的人体半径模型中超声波传播的FDTD仿真研究

Physics in Medicine Pub Date : 2020-12-01 DOI: 10.1016/j.phmed.2020.100029

Masaya Saeki , Leslie Bustamante , Takashi Misaki , Ko Chiba , Isao Mano , Yoshiki Nagatani , Mami Matsukawa

{"title":"FDTD simulation study of ultrasonic wave propagation in human radius model generated from 3D HR-pQCT images","authors":"Masaya Saeki , Leslie Bustamante , Takashi Misaki , Ko Chiba , Isao Mano , Yoshiki Nagatani , Mami Matsukawa","doi":"10.1016/j.phmed.2020.100029","DOIUrl":"10.1016/j.phmed.2020.100029","url":null,"abstract":"<div><p>A finite-difference time-domain (FDTD) technique was used to model the complex propagation of ultrasonic waves through the human radius. A three-dimensional model of the radius, including its uniaxial anisotropy and heterogeneity, was created using structural data obtained from high-resolution peripheral quantitative computed tomographic images. FDTD simulations were performed to achieve adequate wave convergence on the virtual fracture site in the mid shaft of a long cortical bone. The simulation comprised two steps. The first involved wave propagation from the virtual fracture site to two ring-shaped outside receiver arrays. In the second step, the receiver arrays functioned as transmitters, generating re-radiated waves based on the arrival times of the received waves. The re-radiated waves propagating from the transducer arrays were found to converge around the fracture site. Our findings will help to improve the propagation of ultrasonic irradiation through a cast to target a fracture site.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"10 ","pages":"Article 100029"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2020.100029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44639015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS) 利用等离子体功能化光寻址电位传感器(LAPS)对微流体通道内细胞外酸化进行差分化学成像

Physics in Medicine Pub Date : 2020-12-01 DOI: 10.1016/j.phmed.2020.100030

Dua Özsoylu , Sefa Kizildag , Michael J. Schöning , Torsten Wagner

{"title":"Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS)","authors":"Dua Özsoylu , Sefa Kizildag , Michael J. Schöning , Torsten Wagner","doi":"10.1016/j.phmed.2020.100030","DOIUrl":"10.1016/j.phmed.2020.100030","url":null,"abstract":"<div><p>Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more <em>in vivo</em>-like behavior, which is critical to gain more realistic <em>in vitro</em> results from the analyses, e.g., drug discovery experiments. In this work, O<sub>2</sub> plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O<sub>2</sub> plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO–K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO–K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"10 ","pages":"Article 100030"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2020.100030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43873221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Giga-Hertz ultrasonic microscopy: Getting over the obscurity- A short review on the biomedical applications 千兆赫超声显微镜:克服模糊-生物医学应用的简短回顾

Physics in Medicine Pub Date : 2020-06-01 DOI: 10.1016/j.phmed.2020.100025

Esam T. Ahmed Mohamed, Nico F. Declercq

{"title":"Giga-Hertz ultrasonic microscopy: Getting over the obscurity- A short review on the biomedical applications","authors":"Esam T. Ahmed Mohamed, Nico F. Declercq","doi":"10.1016/j.phmed.2020.100025","DOIUrl":"10.1016/j.phmed.2020.100025","url":null,"abstract":"<div><p>Scanning acoustic microscopy in the gigahertz regime (GHz-SAM) has long been a versatile and complementary micro and nanoscopic imaging and analysis tool. Nevertheless, it remained obscured to some extent, compared to its counterparts, such as atomic force microscopy (AFM), despite its unique capability of subsurface analysis. Some current research in our lab at Georgia Tech Lorraine is devoted to the use of the subsurface imaging of GHz-SAM in biological tissues, which has been restricted, mostly, to very stiff materials, in terms of acousto-mechanical impedance, such as metals.</p><p>The feasibility, degrees of complexity, the different techniques, and future fates of (GHz-SAM) are discussed with particular focus on those most used in the biological applications, such as the combined phase and magnitude contrasts acoustic microscopy.</p><p>This paper gives a general overview of SAM, the peculiarities of GHz-SAM with emphasis on the restrictions that led to the semi-obscurity of GHz-SAM so far, and reveals some recent research developments in this field in our laboratory.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"9 ","pages":"Article 100025"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2020.100025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43857545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

In-vivo pilot study at 3 Tesla: Feasibility of Electric Properties Tomography in a rat model of stroke 3特斯拉的体内实验研究:脑卒中大鼠模型电特性断层扫描的可行性

Physics in Medicine Pub Date : 2020-06-01 DOI: 10.1016/j.phmed.2019.100024

Ulf Jensen-Kondering , Liang Shu , Ruwen Böhm , Olav Jansen , Ulrich Katscher

{"title":"In-vivo pilot study at 3 Tesla: Feasibility of Electric Properties Tomography in a rat model of stroke","authors":"Ulf Jensen-Kondering , Liang Shu , Ruwen Böhm , Olav Jansen , Ulrich Katscher","doi":"10.1016/j.phmed.2019.100024","DOIUrl":"10.1016/j.phmed.2019.100024","url":null,"abstract":"<div><h3>Background</h3><p>Electrical Properties Tomography (EPT) is a new sequence which delivers information on tissue electrical conductivity. It has been mostly used for tumor imaging. Ischemic stroke is another promising application. The aim of this study was to demonstrate the feasibility of EPT in a rodent model of stroke.</p></div><div><h3>Methods</h3><p>Wistar rats with and without temporary middle cerebral occlusion (MCAo) were examined in a 3T scanner. EPT was performed using a Steady-State Free-Precession (SSFP) sequence. From the transceive phase ɸ of these SSFP scans, conductivity σ was estimated by the equation σ = Δɸ/(2μ<sub>0</sub>ω) with Δ the Laplacian operator, μ<sub>0</sub> the magnetic permeability, and ω the Larmor frequency. Subsequently, a median filter was applied.</p></div><div><h3>Results</h3><p>Healthy cortical grey matter, white matter and cerebrospinal fluid showed significantly different conductivity (0.83 ± 0.14 S/m, 0.63 ± 0.06 S/m, 2.33 ± 0.49 S/m, p < 0.05). Infarcted tissue exhibited increased conductivity (1.937 ± 1.347 vs. 0.782 ± 0.429 S/m, p < 0.05).</p></div><div><h3>Conclusion</h3><p>EPT is feasible in a rodent model of stroke. Infarcted tissue after MCAo exhibited increased conductivity. Further in-vivo experiments with examination of the influence of reperfusion status and temporal evolution of the infarcted areas should be conducted.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"9 ","pages":"Article 100024"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2019.100024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49386614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Development of a spatially and timely resolved CFD model of a steam sterilizer to predict the load temperature and the theoretical inactivation of bacteria based on sterilization parameters 建立了基于灭菌参数的蒸汽灭菌器空间实时解析CFD模型，以预测负载温度和细菌的理论灭活

Physics in Medicine Pub Date : 2019-12-01 DOI: 10.1016/j.phmed.2019.100020

Manuel Feurhuber , Paul Burian , Marino Magno , Marco Miranda , Christoph Hochenauer

{"title":"Development of a spatially and timely resolved CFD model of a steam sterilizer to predict the load temperature and the theoretical inactivation of bacteria based on sterilization parameters","authors":"Manuel Feurhuber , Paul Burian , Marino Magno , Marco Miranda , Christoph Hochenauer","doi":"10.1016/j.phmed.2019.100020","DOIUrl":"10.1016/j.phmed.2019.100020","url":null,"abstract":"<div><p>This paper presents a CFD model to predict the fluid flow, fluid temperature, load temperature and the theoretical inactivation of bacteria in a modern steam sterilizer, with three significant modifications compared to current state-of-the-art simulations of steam sterilizers. 1) The fluid and the load temperature was investigated for unwrapped load. Measurements of the fluid temperature and the load temperature were performed to validate the CFD model. The average error between the simulated and the measured temperatures was below 0.4 K. 2) The steam quality inside a steam sterilizer was investigated for unwrapped load. With the developed CFD model it is possible to predict the steam quality inside the steam sterilizer spatially and temporally resolved. 3) A first order reaction kinetic approach was added to the CFD model to predict the theoretical inactivation of two different types of bacteria in the steam sterilizer, as well as on the surface of the unwrapped load based on sterilization parameters. The results indicate that the CFD model is able to predict the theoretical inactivation of bacteria on the surface of the load, based on sterilization parameters.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"8 ","pages":"Article 100020"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2019.100020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43421854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Application of multi-channel differential optical density on fast detection of degree of traumatic dural hematoma 多通道差分光密度在外伤性硬脑膜血肿程度快速检测中的应用

Physics in Medicine Pub Date : 2019-06-01 DOI: 10.1016/j.phmed.2019.100015

Huiquan Wang , Fang Xia , Songlin Yu , Zhe Zhao , Jinhai Wang

{"title":"Application of multi-channel differential optical density on fast detection of degree of traumatic dural hematoma","authors":"Huiquan Wang , Fang Xia , Songlin Yu , Zhe Zhao , Jinhai Wang","doi":"10.1016/j.phmed.2019.100015","DOIUrl":"10.1016/j.phmed.2019.100015","url":null,"abstract":"<div><p>Due to the advantages of rapid and non-invasive detection of traumatic dural hematoma using near-infrared differential optical density method, this technology has become a hot research topic in tissue optics in recent years and has important applications in clinical emergency treatment. To further improve the detection accuracy of traumatic subdural hematoma degree, in this paper, a multi-channel differential optical density method was used to obtain the bilaterally-symmetric optical density data of brain. A calibration model with the optical absorption coefficient of the brain tissue and the differential optical density was established using the partial least squares method to predict intracranial epidural hematoma. Simulation results show that the average relative error of the absorption coefficient of dural hematoma using the prediction model was 11.16% and the average relative error on hematoma depth prediction was less than 1%. The model meets the demands of noninvasive traumatic subdural hematoma degree detection. By introducing multi-channel differential optical density method into the noninvasive detection of subdural hematoma, the effects of individual differences on the detection result could be eliminated significantly and the detection accuracy of traumatic subdural hematoma degree can be improved.</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"7 ","pages":"Article 100015"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2019.100015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42676517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecularly imprinted polymers to detect profenofos and carbofuran selectively with QCM sensors 分子印迹聚合物与QCM传感器选择性检测丙烯醚和呋喃

Physics in Medicine Pub Date : 2019-06-01 DOI: 10.1016/j.phmed.2019.100016

Wongduan Sroysee , Suticha Chunta , Maliwan Amatatongchai , Peter A. Lieberzeit

{"title":"Molecularly imprinted polymers to detect profenofos and carbofuran selectively with QCM sensors","authors":"Wongduan Sroysee , Suticha Chunta , Maliwan Amatatongchai , Peter A. Lieberzeit","doi":"10.1016/j.phmed.2019.100016","DOIUrl":"10.1016/j.phmed.2019.100016","url":null,"abstract":"<div><p>Two different molecularly imprinted polymers (MIP) were designed to selectively bind the insecticides carbofuran (CBF) and profenofos (PFF). CBF-MIP are based on methacrylic acid (MAA) as a functional monomer, ethylene glycol dimethacrylate (EGDMA) as a crosslinker, and azobisisobutyronitrile (AIBN) as an initiator. The PFF-MIP comprised of polyurethane based on poly (4-vinylphenol) (PVP), and diphenyl methane-4,4′-di-isocyanate (DPDI) as functional monomers, phloroglucinol (PG) as the cross-linker, and diphenylmethane (DPM) as the porogen. For sensor measurement, MIPs were spin-coated onto one electrode pair of a dual-electrode QCM, while the second pair was spin-coated with NIPs. Fourier transform infrared (FT-IR) spectroscopy confirms successful template removal from the polymer matrix. The resulting CBF- and PFF-MIP coated onto quartz crystal microbalances (QCMs) lead to pesticide QCM sensors revealing the following analytical characteristics, respectively: dynamic detection range of 0.5–1000 μM for CBF-MIP and 10–1000 μM for PFF-MIP. In both cases, the MIP exhibit roughly ten times higher sensor signals, than the corresponding non-imprinted polymers (NIP).</p></div>","PeriodicalId":37787,"journal":{"name":"Physics in Medicine","volume":"7 ","pages":"Article 100016"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.phmed.2019.100016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47116876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28