OpenNanoPub Date : 2024-08-15DOI: 10.1016/j.onano.2024.100212
Layth L. Hamid , Thamer Y. Mutter , Asmiet Ramizy
{"title":"Date palm pollen: A novel medium for bacterial culture and biosynthesis of antibacterial chromium oxide nanoparticles","authors":"Layth L. Hamid , Thamer Y. Mutter , Asmiet Ramizy","doi":"10.1016/j.onano.2024.100212","DOIUrl":"10.1016/j.onano.2024.100212","url":null,"abstract":"<div><p>Medical companies and research centers seek cost-effective alternative culture media containing the necessary nutritional requirements for bacterial cultivation because of high manufacturing and production costs. Date palm pollen (DPP) is an inexpensive and rich natural plant resource that can be easily collected in large quantities. In this study, DPP was used to prepare a novel enriched culture medium that successfully cultivated pathogenic bacteria and <em>Streptomyces</em> spp. without any additives and at a low concentration of 10 g per 1 L of distilled water (DW). Active compounds in DPP were detected by GCMS–, and results show the highest ratio of urea (45 %) among other components. For the first time, DPP was used to synthesize Cr<sub>2</sub>O<sub>3</sub> NPs by an environment-friendly and inexpensive green method. DPP urea plays an important role as a reducing and stabilizing agent in the biosynthesis of Cr<sub>2</sub>O<sub>3</sub> NPs. The obtained NPs were characterized using UV–Vis, FTIR, XRD and SEM. The results of agar disk diffusion ranging between 12 – 20 mm while the MIC for Cr<sub>2</sub>O<sub>3</sub> NPs ranging between 1.56 – 25 U/mL indicated the effectiveness of Cr<sub>2</sub>O<sub>3</sub> NPs in antibacterial activity against a wide range of pathogenic bacteria. Cr<sub>2</sub>O<sub>3</sub> NPs showed a high inhibition ratio that reach 78 % against biofilms produced by <em>P. aeruginosa</em>. For later studies we expect that DPP can be used to prepare selective and other culture media after adding certain materials or antibiotics. The antibacterial and anti-biofilm activity of Cr<sub>2</sub>O<sub>3</sub> NPs could be promising in medical and pharmaceutical applications.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"19 ","pages":"Article 100212"},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000136/pdfft?md5=0a4ce99b15e3612bbff12468c20f6103&pid=1-s2.0-S2352952024000136-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142002177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resveratrol-loaded lipid-based nanocarriers for topical delivery: Comparative physical properties and antioxidant activity","authors":"Wipada Samprasit , Phuvamin Suriyaamporn , Pornsak Sriamornsak , Praneet Opanasopit , Benchawan Chamsai","doi":"10.1016/j.onano.2024.100211","DOIUrl":"https://doi.org/10.1016/j.onano.2024.100211","url":null,"abstract":"<div><p>Resveratrol (R) is an antioxidant that helps several aspects of aging skin. However, it is slightly soluble in water and unstable under light exposure, necessitating the use of suitable formulations for improved clinical efficacy. Therefore, this study aimed to prepare R-loaded lipid-based nanocarriers for topical delivery, <em>i.e.</em>, nanostructured lipid carriers (NLCs) and nanoemulsions (NEs). R-loaded nanocarrier gels were further prepared to increase R loading. The comparative physical properties and antioxidant activity of nanocarriers were performed in terms of particle size, zeta potential, morphology, rheology, R content, <em>in vitro</em> release, antioxidant activity, cytotoxicity and stability. The results revealed that R was successfully loaded into NLCs and NE gels (NEGs), having different physical properties and antioxidant activity depending on the composition of lipid-based nanocarriers. R could be incorporated into NEs and the aqueous gelling phase, resulting in higher R loading. Furthermore, the gelling network was responsible for pseudoplastic flow behavior. The cumulative amount of R released from NEGs was significantly higher than that from NLCs due to the co-surfactant-like properties of NEGs, which resulted in smaller particle sizes. However, NLCs exhibited significantly more antioxidant activity and less cytotoxicity compared to NEGs. The stability of both nanosystems showed no significant change when stored at refrigerator temperature for over 3 months. In conclusion, the various compositions of lipid-based nanocarriers produced a range of physical properties and antioxidant activity. Nonetheless, these NLCs and NEGs have the potential to be nanocarriers for R, which has antioxidant properties for topical application.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"19 ","pages":"Article 100211"},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000124/pdfft?md5=6ea5858529272364e129f259c6db7fc3&pid=1-s2.0-S2352952024000124-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OpenNanoPub Date : 2024-06-03DOI: 10.1016/j.onano.2024.100210
Zenli Cheng , Zi Yin Wong , S. Ramkanth , Cheng Wan Hee , Mohamed Saleem TS , Saminathan Kayarohanam , M Yasmin Begum , Kushagra Khanna , Abhishek Kumar , Ashok Kumar Janakiraman
{"title":"Colchicine-capped ZnO nanoparticles: Elucidation of their cytotoxicity potential against MDA-MB 231 cancer cells","authors":"Zenli Cheng , Zi Yin Wong , S. Ramkanth , Cheng Wan Hee , Mohamed Saleem TS , Saminathan Kayarohanam , M Yasmin Begum , Kushagra Khanna , Abhishek Kumar , Ashok Kumar Janakiraman","doi":"10.1016/j.onano.2024.100210","DOIUrl":"10.1016/j.onano.2024.100210","url":null,"abstract":"<div><p>This research descibes a pioneering approach aimed at preparing zinc oxide nanoparticles (ZnO-NPs) with colchicine as the reducing and capping agent. Colchicine-loaded ZnO-NPs (CHZnO-NPs) were prepared by adding colchicine to the zinc sulfate heptahydrate solution. The CHZnO-NPs formulation was then characterized to determine the morphology, size, crystallinity, elemental composition and vibrational properties. Upon characterization, CHZnO-NPs were studied for their cytotoxic effect against the breast cancer cell line (MDA-MB-231). The successful biosynthesis of CHZnO-NPs was initially confirmed visually by the changes in the mixture color, from light-yellow to white cloudy. The best CHZnO-NPs formulation selected was F3, which possessed 10 mg/mL of colchicine. Formulation (F3) had the smallest mean particle diameter of 43.77 nm and the lowest zeta potential of −19.60 mV. It also had 92.21 ± 0.012 % encapsulation efficiency and 20.86 ± 0.005 % drug loading. Formulation (F3) displayed a hexagonal wurtzite structure with irregular morphology. The observation of colchicine peaks on the FTIR spectra of F3 proved the role of colchicine as a reducing and capping agent during the synthesis of ZnO-NPs. Besides, the <em>in-vitro</em> cell cytotoxicity study on the MDA-MB-231 cell line revealed a significant reduction in cell proliferation at the concentration of 25 μg of colchicine and F3. Further, studies on the cellular migration potential also demonstrated concentration-dependent activity. Overall, CHZnO-NPs were shown to be successfully synthesized via an environmental-friendly procedure and colchicine acted as a capping agent to regulate the particle size, and aggregation, in addition to its anticancer properties.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"18 ","pages":"Article 100210"},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000112/pdfft?md5=cbf873dad602013c256184e72ed60d02&pid=1-s2.0-S2352952024000112-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141279759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OpenNanoPub Date : 2024-05-17DOI: 10.1016/j.onano.2024.100208
Himanshu Sekhar Panda, Samraggi Choudhury, Jiban Jyoti Panda
{"title":"Nucleic acid nano-carriers for delivery of antisense and RNAi therapeutics","authors":"Himanshu Sekhar Panda, Samraggi Choudhury, Jiban Jyoti Panda","doi":"10.1016/j.onano.2024.100208","DOIUrl":"10.1016/j.onano.2024.100208","url":null,"abstract":"<div><p>Nucleic acid nanotechnology presents an exciting approach for manufacturing tailored nanoscale biomaterials with precise structures, spatial precision, and exceptional biocompatibility. These nucleic acid-based nanomaterials, here referred as nano-carriers can have versatile applications in bio-imaging, diagnostics, and therapy. In this review, we have surveyed the progress made in the field of multifunctional nucleic acid nano-carriers, particularly in the context of delivering antisense and RNA interference (RNAi) therapeutics. RNAi technology has emerged as a potent modality for conducting functional genomic analyses and holds potential as an effective approach for crafting targeted gene-silencing treatments for viral infections, cancer, and other diseases in the future. Our focus is on exploring RNAi as a therapeutic avenue, taking into account challenges such as the expense of RNAi triggers, delivering RNAi efficiently to the target site, and addressing off-target and nontarget effects, while also recognizing promising opportunities within the field of biomedical research.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"18 ","pages":"Article 100208"},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000094/pdfft?md5=20366c860ec20135f29b21f3fd554740&pid=1-s2.0-S2352952024000094-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OpenNanoPub Date : 2024-05-16DOI: 10.1016/j.onano.2024.100209
Alrayan F. Nahhas , Alaa F. Nahhas , Thomas J. Webster
{"title":"The nano and artificial intelligence effect: Improved magnetic resonance imaging volumetry for multiple sclerosis","authors":"Alrayan F. Nahhas , Alaa F. Nahhas , Thomas J. Webster","doi":"10.1016/j.onano.2024.100209","DOIUrl":"10.1016/j.onano.2024.100209","url":null,"abstract":"<div><p>Magnetic Resonance Imaging (MRI) is a widely established method for monitoring and diagnosing neurological diseases, including multiple sclerosis (MS). MS is a disease that continuously progresses and in due course involves the progressive atrophy of neural structures (such as brain gray and white matter) leading to debilitation. Clearly, the earlier that MS can be detected, the better the chances of eventual treatment to slow down disease progression. While conventional MRI volumetry, as a non-invasive imaging technique that measures the exact volume of different brain structures, has improved the diagnosis of brain atrophy, problems still exist. This review introduces and summarizes the seminal role that nanotechnology (in terms of novel materials for improved MS diagnosis and treatment) and artificial intelligence (in terms of enhancing images via computer algorithms and novel contrast agents) are playing in improving volumetric MRI. In doing so, this one-of-a-kind review manuscript establishes how nanotechnology and artificial intelligence is improving, and will continue to improve, volumetric MRI diagnosis and treatment of MS.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"18 ","pages":"Article 100209"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000100/pdfft?md5=bf67a72f48a641e38736e831df3f694f&pid=1-s2.0-S2352952024000100-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141039447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing the efficacy of monolaurin against SARS-CoV-2 and influenza A (H1N1) with a nanoemulsion formulation","authors":"Yotsanan Weerapol , Suwisit Manmuan , Sontaya Limmatvapirat , Chutima Limmatvapirat , Jitnapa Sirirak , Poomipat Tamdee , Sukannika Tubtimsri","doi":"10.1016/j.onano.2024.100207","DOIUrl":"https://doi.org/10.1016/j.onano.2024.100207","url":null,"abstract":"<div><p>Monolaurin was utilized to formulate temperature-driven phase inversion nanoemulsions containing lesser galangal essential oil, fixed oil, and Cremophor RH40, with aim for eradicating enveloped viruses. Results showed that the droplet size of the nanoemulsion depended on lesser galangal essential oil–fixed oil ratio, monolaurin concentration, and oil concentration. Nanoemulsions prepared from lesser galangal essential oil–perilla oil (60:40) exhibited approximately 50-nm nanosized droplets and high entrapment efficiency (98.68 % ± 2.45 %). After storage at 25 °C for 1 year, droplet size did not vary significantly from the initial size, and monolaurin content was >95 %, indicating good physical and chemical stability. The monolaurin was located at the oil–water interface as indicated by a two-dimensional nuclear Overhauser effect nuclear magnetic resonance spectroscope and computer simulation. The 0.2% w/v monolaurin nanoemulsion inhibited SARS-CoV-2 and influenza A (H1N1) viruses with efficacy more than 3 log reduction (99.90 %) and low cytotoxicity. Hence, the monolaurin nanoemulsion can successfully eradicate enveloped viruses, especially SARS-CoV-2 and influenza A (H1N1).</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"17 ","pages":"Article 100207"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000082/pdfft?md5=7a75428e4f2dea7e4d1354e4ef72f90e&pid=1-s2.0-S2352952024000082-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140815770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OpenNanoPub Date : 2024-05-01DOI: 10.1016/j.onano.2024.100206
Galal Mohsen Hussein Al-sayadi , Gurisha Garg , Arti Singh , Preeti Patel , Ghanshyam Das Gupta , Balak Das Kurmi
{"title":"Development of QCT loaded TPGS coated solid lipid nanoparticles for improved in vivo neuroprotective activity in LPS administered adult zebrafish model: A QbD-based approach","authors":"Galal Mohsen Hussein Al-sayadi , Gurisha Garg , Arti Singh , Preeti Patel , Ghanshyam Das Gupta , Balak Das Kurmi","doi":"10.1016/j.onano.2024.100206","DOIUrl":"10.1016/j.onano.2024.100206","url":null,"abstract":"<div><p>This work contains the development of QCT-loaded TPGS-coated SLNs by QbD to enhance neuroinflammation potential. Developed SLNs were in the nanometer range (263±3.62 nm) with desired parameters i.e., PDI (0.244±0.003), zeta potential (28.2 ± 0.74 mV), and%EE (74.3 ± 2.45 %) respectively. The release study showed sustained drug release of the developed formulation T-QCT-SLN (83.2 % release in 48 h). The study found QCT can reduce oxidative stress and neuroinflammation in adult zebrafish. Results showed reduced disruption in neuronal cells, decreased TNF-α and IL-1β levels, and reduced LPO, nitrite, and AChEs levels while increasing GSH levels, indicating its potential for treating oxidative stress and neuroinflammation. It can be concluded that QCT-loaded TPGS-coated SLN effectively prevents oxidative damage and neuroinflammation in adult zebrafish exposed to LPS compared to the QCT alone. The suggested work will be a focal paradigm for neuroinflammatory drug delivery.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"17 ","pages":"Article 100206"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000070/pdfft?md5=2f96f069582f6cd38085cfa670ced3c3&pid=1-s2.0-S2352952024000070-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140762690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OpenNanoPub Date : 2024-03-21DOI: 10.1016/j.onano.2024.100205
Jorge Alejandro Barbosa-Nuñez , Sara Elisa Herrera-Rodríguez , Eristeo García-Márquez , Hugo Espinosa-Andrews
{"title":"A comparative study on the physicochemical properties and gastrointestinal delivery of calcium niosomes produced by low and high-energy techniques","authors":"Jorge Alejandro Barbosa-Nuñez , Sara Elisa Herrera-Rodríguez , Eristeo García-Márquez , Hugo Espinosa-Andrews","doi":"10.1016/j.onano.2024.100205","DOIUrl":"10.1016/j.onano.2024.100205","url":null,"abstract":"<div><p>Since the bioavailability of calcium from foods and supplements is low, its encapsulation in niosomes is proposed as a potential solution to this issue. This study aimed to compare the physiochemical properties and release profiles of niosomes with calcium chloride and calcium lactate produced by injection and sonication methods. The size distribution (200–300 nm), encapsulation efficiency (20–40 %), stability, release profile, cytotoxicity, and calcium bioavailability of the niosomes were characterized. The production method, rather than the calcium salt used, impacted the properties of the niosomes. Calcium release under gastrointestinal conditions was dependent on both the calcium source and the production method, which was characterized by a Peppas-Sahlin release model. Calcium niosomes were not cytotoxic to intestinal cells. All the calcium niosomes showed high bioavailability in cells (5–20 % greater than the control) but lower bioavailability than the non-encapsulated calcium salts (80–110 % above control) due to their high solubility. Nevertheless, the use of niosomes might be a promising approach for improving calcium bioavailability.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"17 ","pages":"Article 100205"},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000069/pdfft?md5=e1988301879094919cc6233f1db3218c&pid=1-s2.0-S2352952024000069-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140281513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OpenNanoPub Date : 2024-03-01DOI: 10.1016/j.onano.2024.100202
Poomsith Thangsan, Khemika Wannakan, Suwat Nanan
{"title":"Biosynthesis of ZnO using Senna siamea leaf extract for photodegradation of tetracycline antibiotic and azo dye in wastewater","authors":"Poomsith Thangsan, Khemika Wannakan, Suwat Nanan","doi":"10.1016/j.onano.2024.100202","DOIUrl":"https://doi.org/10.1016/j.onano.2024.100202","url":null,"abstract":"<div><p>The green fabrication of photocatalyst is an interesting research topic owing to the beneficials of non-toxicity, simplicity, and environmentally friendly. In this research, we report the biosynthesis of ZnO by a hydrothermal/solvothermal method with addition of leaf extract (using either water or ethanol as a solvent) of <em>Senna siamea.</em>. The prepared ZnO was used for removal of tetracycline (TC) antibiotic and reactive red 141 (RR141) azo dye. The complete degradation of the pollutant was achieved under both UV light (120 min) and sunlight (40 min). The ZnO-SV400, solvothermally grown using ethanol extract and then calcined at 400 °C, showed promising photoactivity assigning to the increment of the photogenerated charge carrier separation capacity and high crystallinity of the sample after thermal treatment. The degradation reaction follows nicely with the first-order reaction with a rate constant of 0.081 min<sup>−1</sup>. The result shows that hydroxyl radicals are the key spices involved in the detoxification of the contaminants. The recycling ability of about five cycles was reported. The structural stability was also confirmed. The strategy presented here demonstrates that the green synthesis with addition of plant extracts is the main parameter governing the fabrication of sunlight-active ZnO photocatalyst for detoxification of the toxic contaminants including organic dyes and antibiotics in wastewater.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"16 ","pages":"Article 100202"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000033/pdfft?md5=d7632c6783636c778adfa4a60f4f3d93&pid=1-s2.0-S2352952024000033-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140052610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OpenNanoPub Date : 2024-03-01DOI: 10.1016/j.onano.2024.100203
Sajed Nikmehr , Mahmood Kazemzad , Mohammad Mehdi Sabzehmeidani , Leila Nikzad , Touradj Ebadzadeh
{"title":"Structural characteristics of Zn-MOFs and derived zinc oxide by X-ray diffraction peak analysis fabricated by mechanical and hydrothermal methods","authors":"Sajed Nikmehr , Mahmood Kazemzad , Mohammad Mehdi Sabzehmeidani , Leila Nikzad , Touradj Ebadzadeh","doi":"10.1016/j.onano.2024.100203","DOIUrl":"https://doi.org/10.1016/j.onano.2024.100203","url":null,"abstract":"<div><p>In this work, the Zn based MOFs were synthesized from cyanoguanidine and zinc acetate source precursors via two hydrothermal methods and high energy ball milling technique and also the free salt and bimetallic samples have been synthesized. Then, the fabricated Zn-MOFs were heat for calcination at 550 °C for 110 min. The synthesized nanostructures were examined by XRD, SEM and FTIR analysis to gain insight about structure, morphology and functional groups properties. The results confirm that it is possible to prepare Zn MOFs using high energy ball milling methods. Besides, the fabricated MOF and complex structures can be converted to porous zinc oxide (ZnO) by a simple thermal annealing in air. Then, the line broadening of ZnO from mechanochemical and hydrothermal methods was showed due to the small crystallite size and lattice strain. The broadening was studied by the Scherrer formula and Williamson Hall (UDM, USDM, UDEDM) and Size-strain plot techniques. In addition, undesirable phases may affect the synthesized part during thermal cycles. We demonstrate the potential of using high-energy X-ray diffraction for detailed analysis of minority phases in ZnO-derived components.</p></div>","PeriodicalId":37785,"journal":{"name":"OpenNano","volume":"16 ","pages":"Article 100203"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352952024000045/pdfft?md5=36c458edeea1231955b9bbf37335cf82&pid=1-s2.0-S2352952024000045-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}