Journal of Photochemistry and Photobiology最新文献

{"title":"Wavelength dependent excited state dynamics observed in canonical pyrimidine nucleosides","authors":"Peicong Wu ,&nbsp;Xueli Wang ,&nbsp;Haifeng Pan ,&nbsp;Jinquan Chen","doi":"10.1016/j.jpap.2023.100211","DOIUrl":"https://doi.org/10.1016/j.jpap.2023.100211","url":null,"abstract":"<div><p>Epidemiological evidence indicates that damage to DNA/RNA initialized by ultraviolet (UV) radiation is associated with skin cancer. Wavelength dependence of DNA photodamage was proposed as early as 1990s and demonstrated later on. Unraveling the photo-activated dynamics involved in related reactions is essential. However, studies aimed at uncovering the wavelength dependent excited state dynamics in canonical pyrimidine nucleosides have not received enough attention. In this work, excitation wavelength dependent excited state dynamics of 2′-deoxy-thymidine (dThd) and oxy-uridine (Urd) are investigated in acetonitrile solutions by femtosecond broadband transient absorption spectroscopy. Varying the excitation wavelength leads to a significant difference in the branching of the excited state population at the Franck-Condon (FC) region, resulting higher fluorescence quantum yield with 285 nm pump but higher triplet state quantum yield under 267 nm excitation. Based on our results, a vibronic coupling regulated excited state relaxation mechanism is proposed. This mechanism information is important for understanding the formation of harmful photoproducts for DNA/RNA with different wavelength UV excitations.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"18 ","pages":"Article 100211"},"PeriodicalIF":3.261,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666469023000520/pdfft?md5=b6bc14c3344c50f92048e9fa333679de&pid=1-s2.0-S2666469023000520-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92135449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of photobiomodulation auriculotherapy in the treatment of temporomandibular disorders: A double-blind randomized feasibility study","authors":"Sara Lisboa Marques ,&nbsp;Andressa Cristine da Silva Ramos ,&nbsp;Érika Almeida Boggiss ,&nbsp;Rosana Aparecida de Lima ,&nbsp;Carina Ferreira Pinheiro-Araújo ,&nbsp;Adriana Teresa Silva Santos ,&nbsp;Andréia Maria Silva Vilela Terra","doi":"10.1016/j.jpap.2023.100210","DOIUrl":"https://doi.org/10.1016/j.jpap.2023.100210","url":null,"abstract":"<div><h3>Introduction</h3><p>Temporomandibular disorders (TMD) are considered the most common complaint associaetd with orofacial pain. A treatment approach for TMD is photobiomodulation auriculotherapy, however, a method that which still requires studies mainly with pulsed frequency.</p></div><div><h3>Objective</h3><p>To evaluate the feasibility of conducting a randomized clinical trial using pulsed frequency photobiomodulation auriculotherapy and determine the relevant sample size.</p></div><div><h3>Methods</h3><p>The study was a controlled randomized pilot study. Twenty one volunteers with TMD were randomized into experimental and placebo groups. The evaluation periods were pre-intervention and again after four weeks. The instruments used for the assessment were axis I (mandibular movement measurements [MMM]) and axis II (Graded Chronic Pain Scale [GCPS], Jaw Functional Limitation Scale [JFLS-8], The Patient Health Questionnaire [PHQ-4], and Generalized Anxiety Disorder [GAD-7]) from Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Mann–Whitney and Wilcoxon tests were used for comparison of groups. The intervention protocol was performed once a week for foour weeks.</p></div><div><h3>Results</h3><p>The GCPS question about “pain at this exact moment” indicated lower values for the treated group compared to the placebo group (<em>U</em> = 15.50; <em>p</em> = 0.005) after the intervention. The calculation of the total sample was 22 volunteers. The JFLS-8 variable showed no difference between the groups and the sample calculation ranged from 39 to 281 volunteers. The MMM showed no difference between the groups, and the calculation of the necessary sample ranged from 27 to 2.317. The variable PHQ-4 (<em>U</em> = 21.00; <em>p</em> = 0.02) and GAD-7 (<em>U</em> = 20.00; <em>p</em> = 0.02) showed differences between groups with type I error. The required sample was 22 volunteers for PHQ-4 and 25 for GAD-7.</p></div><div><h3>Conclusion</h3><p>We conclude that this study is feasible and that the required sample should be 11 volunteers for each group in the GCPS subitem “pain intensity at this exact moment”. We were able to find results for this GCPS subitem. However, for other variables we need 25 volunteers for GAD7 and 22 volunteers for PHQ-4. Other variables, such as JFLS-8 and MMM, made it impossible to conduct these scales for future studies.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"18 ","pages":"Article 100210"},"PeriodicalIF":3.261,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666469023000519/pdfft?md5=0a20a6411d401d9fd02519618898c164&pid=1-s2.0-S2666469023000519-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91955583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Light-mediated double-strand DNA cleavage by an alkyldicobalamin","authors":"Liberty N. Gendron ,&nbsp;Jennifer R. Shell ,&nbsp;Thomas A. Shell","doi":"10.1016/j.jpap.2023.100209","DOIUrl":"https://doi.org/10.1016/j.jpap.2023.100209","url":null,"abstract":"<div><p>Agents that cause double-strand breaks (DSBs) of DNA via radical formation have been demonstrated to be effective in treating cancer because DSBs result in cellular apoptosis. Light-responsive agents for the treatment of cancer have been of interest for decades because they afford the ability to spatially control chemical reactions limiting the effects by controlling the area of illumination. Alkylcobalamins, which are structurally related to Vitamin B₁₂ (B₁₂), produce radicals with very high quantum yields when illuminated with green light (approximately 530 nm). Cancerous cells uptake alkylcobalamins to a greater extent than healthy cells because these rapidly dividing cells have an increased demand for B₁₂. Tethering two cobalamins with a propyl group results in a complex that causes true DNA DSBs in a light-mediated manner.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"18 ","pages":"Article 100209"},"PeriodicalIF":3.261,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666469023000507/pdfft?md5=48171624bd74a2929e21c4124fd20672&pid=1-s2.0-S2666469023000507-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92042282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anionic clay surface facilitates electron transfer between an excited donor encapsulated within a cationic capsule and a cationic electron acceptor","authors":"Natsuki Morita ,&nbsp;A. Mohan Raj ,&nbsp;Takuya Fujimura ,&nbsp;Tetsuya Shimada ,&nbsp;Vaidhyanathan Ramamurthy ,&nbsp;Shinsuke Takagi","doi":"10.1016/j.jpap.2023.100204","DOIUrl":"10.1016/j.jpap.2023.100204","url":null,"abstract":"<div><p>Fluorescence quenching of an excited guest encapsulated within a cationic host by a cationic molecule was examined on an anionic inorganic surface. Repulsion between the host and the quencher was overcome by adsorbing both an anionic surface. Dimethyl stilbene (DMS), octa amine (OAm₂¹⁶⁺), viologen derivatives (VD²⁺) and saponite are used as guest, cationic capsule, cationic electron acceptor and anionic inorganic surface, respectively. The fluorescence behavior of DMS within OAm₂¹⁶⁺ (denoted as DMS@OAm₂¹⁶⁺) was observed by steady-state and time-resolved fluorescence measurements. As a result of electron transfer the fluorescence of DMS@OAm₂¹⁶⁺ was quenched by VD²⁺ under the presence of saponite, while no quenching was observed in the absence of saponite. Those results indicate that the dynamic electron transfer between DMS@OAm₂¹⁶⁺ and VD²⁺ which are electrostatically repulsive, can be observed in the (DMS@OAm₂¹⁶⁺)-VD²⁺-saponite triad supramolecular system where the two cationic systems are brought closer by the anionic clay sheet.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"17 ","pages":"Article 100204"},"PeriodicalIF":3.261,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666469023000453/pdfft?md5=b854b3671fbb856911fab5097706ed8c&pid=1-s2.0-S2666469023000453-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89692356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent progress in photocatalytic reactions involving the excitation of electron-primed catalysts","authors":"Takashi Koike","doi":"10.1016/j.jpap.2023.100205","DOIUrl":"10.1016/j.jpap.2023.100205","url":null,"abstract":"<div><p>Open-shell species are attracting significant attention owing to their unique physicochemical properties and highly reactive characteristics. Over the past decade, photoredox catalysis (<em>PRC</em>) has emerged as a powerful strategy for radical reactions. Recently, photocatalysis involving the excitation of open-shell catalytic species generated from in situ photo- or electrochemical electron transfer has also attracted significant attention in synthetic organic chemistry. These systems can achieve redox potentials that are difficult to achieve in the ground state of the photocatalyst or by simple excitation of the photocatalyst. In this review article, we discuss recent advancements in highly reducing organic photocatalyst (<em>OPC</em>) systems involving the photoexcitation of electron-primed catalytic species, which can be engaged in photochemically (<em>conPET</em>: consecutive photoinduced electron transfer) or electrochemically (<em>e-PRC</em>: electrochemically mediated photoredox catalysis). We believe that expanding the redox windows of catalysts to activate inert substrates from the viewpoint of redox potential will improve rational reaction design, and the use of sophisticated <em>OPC</em> systems will be promising for achieving elusive molecular transformations.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"17 ","pages":"Article 100205"},"PeriodicalIF":3.261,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666469023000465/pdfft?md5=c0b100517e24e17462e3b5d883adf786&pid=1-s2.0-S2666469023000465-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89378025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering mechanism of excited state reactivity by spectroscopic methods","authors":"Sarvar Aminovich Rakhimov,&nbsp;Malcolm D.E. Forbes ,&nbsp;Jayaraman Sivaguru","doi":"10.1016/j.jpap.2023.100207","DOIUrl":"https://doi.org/10.1016/j.jpap.2023.100207","url":null,"abstract":"<div><p>The Feature highlights Electron Paramagnetic Resonance (EPR) spectroscopy as an indispensable tool to understand the excited state reactivity of organic molecules.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"18 ","pages":"Article 100207"},"PeriodicalIF":3.261,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666469023000489/pdfft?md5=bb4cfe76b017842df71429551108563d&pid=1-s2.0-S2666469023000489-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92042281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photoinduced radical generation and trapping by acrylonitrile of N-Boc secondary amine and N-Boc N-methyl α-amino acid ester at α-position using two-molecule photoredox catalysts","authors":"Shoki Nagaya ,&nbsp;Hibiki Miyagawa ,&nbsp;Ryoga Hashimoto ,&nbsp;Toshiki Furutani ,&nbsp;Mugen Yamawaki ,&nbsp;Hirotsugu Suzuki ,&nbsp;Toshio Morita ,&nbsp;Yasuharu Yoshimi","doi":"10.1016/j.jpap.2023.100208","DOIUrl":"https://doi.org/10.1016/j.jpap.2023.100208","url":null,"abstract":"<div><p>The photoreaction of an <em>N</em>-Boc secondary amine and <em>N</em>-Boc <em>N</em>-methyl α-amino acid ester with acrylonitrile using inexpensive two-molecule photoredox catalysts results in the production of α-alkylated amine through the generation of an α-carbamy radical under mild conditions. In particular, this mothed leads to a regioselective modification of <em>N</em>-Boc <em>N</em>-methyl α-amino acid ester with the retention of α-chirality through the generation of the less stable primary α-carbamyl radical.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"18 ","pages":"Article 100208"},"PeriodicalIF":3.261,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"7183322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Excited-state tris(pentafluorophenyl)borane as a strong single-electron oxidant: Photophysical properties and catalysis","authors":"Yoshitaka Aramaki,&nbsp;Yuki Uchida,&nbsp;Ryo Ishikawa,&nbsp;Takashi Ooi","doi":"10.1016/j.jpap.2023.100206","DOIUrl":"10.1016/j.jpap.2023.100206","url":null,"abstract":"<div><p>The photophysical properties and photocatalysis of tris(pentafluorophenyl)borane [B(C₆F₅)₃], known as a strong Lewis acid, were revealed. The excited-state B(C₆F₅)₃ exerts single-electron oxidation capability with an oxidation potential (<em>E</em>_red* = 2.02 V vs SCE) close to those of electronically unbiased toluene derivatives (<em>E</em>_ox = 2.01 to 2.29 V). This property was experimentally proven by the direct observation of the radical cation of the toluene dimer by the transient absorption spectroscopy of a mixture of B(C₆F₅)₃ and toluene. In cooperation with a suitable Brønsted base catalyst, B(C₆F₅)₃ catalytically generated benzylic radicals from toluene derivatives under photoirradiation for subsequent carbon-carbon bond-forming reactions.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"18 ","pages":"Article 100206"},"PeriodicalIF":3.261,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666469023000477/pdfft?md5=1018f8b2d2ddae786dbd516b8204cade&pid=1-s2.0-S2666469023000477-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78590474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal","authors":"Igor Khmelinskii ,&nbsp;Vladimir Makarov","doi":"10.1016/j.jpap.2023.100202","DOIUrl":"https://doi.org/10.1016/j.jpap.2023.100202","url":null,"abstract":"<div><p>Presently we report a second example of a biochemical reaction sensitized remotely by excitons (electronic excited states) efficiently transferred along intermediate filaments (IFs) over macroscopic distances. IFs are excellent conductors of energy in the form of excitons, with the efficiency of ca. 0.53 reported <em>in vitro</em>. Excitons were generated by visible light and propagated along Müller cell (MC) intermediate filaments, about 100 μm long. These experiments used a capillary matrix filled by MC IFs extracted from porcine retina. Excitons induced efficient isomerization of 11-cis- to all-trans-retinal, with the reaction quantum yield <em>φ_cis/trans</em> = 0.347 obtained for 11-cis-retinal concentration of 1.0 × 10⁻³ M (0.284 g/L) using 546 nm light at 6.87 mW/cm² power density. Exciton quantum yield <em>φ_exc</em> at 546 nm was also measured in function of radiation power density, with nonlinearity indicative of biphotonic processes. This is the first case of biphotonic processes occurring at such low light intensities with steady-state illumination. The present results support quantum mechanism of high-contrast vision of vertebrate eyes.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"17 ","pages":"Article 100202"},"PeriodicalIF":3.261,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3207977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implications of visible light and means of photoprotection","authors":"Brittany Lane ,&nbsp;Henry W. Lim ,&nbsp;Iltefat H. Hamzavi ,&nbsp;Tasneem F. Mohammad ,&nbsp;Indermeet Kohli","doi":"10.1016/j.jpap.2023.100203","DOIUrl":"https://doi.org/10.1016/j.jpap.2023.100203","url":null,"abstract":"<div><p>Visible light (VL) has been shown to promote genotoxicity through free radical generation and structural protein degradation. These stressful events promote cellular vulnerability, which manifests clinically as erythema, hyperpigmentation, and photoaging. Having established biologic impacts of VL, development of photoprotection strategies against this part of the solar spectra are warranted. This invited review presents advances in the VL literature and discusses available and potential means of VL photoprotection.</p></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"17 ","pages":"Article 100203"},"PeriodicalIF":3.261,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2956536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}