Case Reports in Veterinary Medicine最新文献

{"title":"Evaluation of a Young Dog for Escalating Aggression Toward Both Familiar and Unfamiliar People.","authors":"Lynn Honeckman","doi":"10.1155/crve/9804544","DOIUrl":"10.1155/crve/9804544","url":null,"abstract":"<p><p>This case report describes the evaluation and successful multimodal treatment of severe, early-onset aggression in a juvenile dog. A 9-month-old spayed female Australian Shepherd presented with escalating aggressive behaviors toward familiar and unfamiliar people, including multiple bite incidents resulting in human injury. Aggression was observed across numerous contexts, including handling, play, resource guarding, visitor interactions, and encounters with people and dogs outside the home. Significant risk factors included early removal from the dam at 6 weeks of age, minimal early socialization, a history of chronic illness during early development, and later-discovered aggressive traits in both parents. Comprehensive medical evaluation, including repeated laboratory testing and neurological assessment, revealed no underlying medical abnormalities. Behavioral diagnoses included generalized anxiety, impulse-control aggression, fear-related aggression, possessive aggression, and socialization deficits. Prior to referral, behavioral issues were minimized by outside advisors, and no psychopharmacologic intervention had been attempted due to the dog's young age. By 9 months, the family was considering rehoming or behavioral euthanasia due to safety concerns and breakdown of the human-animal bond. Treatment consisted of an integrated plan incorporating environmental management, strict safety protocols, positive reinforcement-based behavior modification, and pharmacologic therapy with fluoxetine and gabapentin. Within 6 weeks, the family reported moderate improvement, with marked and sustained improvement following dose adjustments and continued behavior modification. By 14 weeks, aggressive incidents had substantially decreased, and after 1 year of therapy, bite behavior had resolved. Long-term follow-up demonstrated stable improvement, improved tolerance of veterinary handling through cooperative care training, and restoration of household safety and quality of life. This case highlights the importance of early recognition, comprehensive assessment, and timely use of combined behavioral and pharmacologic interventions in juvenile dogs with severe aggression, emphasizing that young age should not preclude appropriate treatment.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"9804544"},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13213711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148057373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual Case of Simultaneous Vaginal and Rectal Prolapse in a Jennet: Clinical Presentation and Management.","authors":"S Saraiva, F Silva, J García-Díez","doi":"10.1155/crve/1125413","DOIUrl":"10.1155/crve/1125413","url":null,"abstract":"<p><p>A 5-year-old adult jennet in late pregnancy was presented for evaluation of a mass protruding from the vagina that had been noticed approximately 8 h earlier. Physical examination revealed a large (15 × 14 × 12.5 cm), pink-to-red vaginal protrusion. The jennet was estimated to be approximately 2-3 weeks from parturition, and the remainder of the physical examination was unremarkable. A diagnosis of vaginal prolapse was made. The prolapse was manually reduced. Foaling occurred 15 days later, with veterinary assistance. Parturition was dystocic, characterized by bilateral forelimb flexion, and required obstetrical intervention. Two months postpartum, the jennet presented with recurrent vaginal prolapse and 1 month later, she subsequently developed a rectal prolapse concurrently with vaginal prolapse. In total, three prolapse events were observed (three vaginal and one rectal). Following parturition, the jennet failed to return to estrus. To the best of the authors' knowledge, no previous cases of vaginal and rectal prolapse in a jennet have been reported.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"1125413"},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13154771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147869760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dilated Cardiomyopathy Phenotype With Global (Four-Chamber) Involvement in a Cat: Echocardiographic, Pathological, Histopathological, and Immunohistochemical Findings.","authors":"Giovanni Romito, Alessandra Costa, Maria Morini","doi":"10.1155/crve/9572640","DOIUrl":"10.1155/crve/9572640","url":null,"abstract":"<p><p>An 8-year-old castrated male Exotic Shorthair cat was referred due to the onset of abdominal effusion. Echocardiography revealed a dilated cardiomyopathy phenotype affecting both ventricles, associated with biatrial dilatation, left atrial dysfunction with spontaneous echocontrast, and right-sided congestive heart failure. Additional diagnostic tests (thoracic radiographs, complete blood cell count, serum biochemistry, assessment of thyroid status, cardiac troponin I and plasma taurine concentrations, and urinalysis) ruled out secondary conditions able to cause a similar echocardiographic phenotype. Despite prompt initiation of cardiac therapy (furosemide, pimobendan, clopidogrel, and rivaroxaban) and subsequent hospitalization for further medical support, the cat's clinical condition deteriorated, ultimately leading to euthanasia. Postmortem examination revealed extensive areas of myofiber thinning with a wavy appearance in both ventricles, closely resembling the attenuated wavy fiber pattern described in dogs affected by dilated cardiomyopathy. Additionally, multifocal replacement of myofibers by adipose tissue was found in both atria. Immunohistochemical analysis showed abnormal expression patterns of desmin, vimentin, and connexin 43, similar to those previously reported in humans and dogs with dilated cardiomyopathy. Given the thorough antemortem and postmortem investigations and the associated findings, a rare case of feline dilated cardiomyopathy with biventricular and biatrial involvement was diagnosed.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"9572640"},"PeriodicalIF":0.0,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13150973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147869797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Abundance of Cytotoxic T Cells in Synovial Fluid of a Dog With Erosive Immune-Mediated Polyarthritis.","authors":"Kohei Murakami, Kosuke Kobayashi, Kenji Kutara, Shin-Ichi Nakamura, Michihito Tagawa, Takamasa Itoi","doi":"10.1155/crve/9048633","DOIUrl":"10.1155/crve/9048633","url":null,"abstract":"<p><p>Most dogs with nonerosive immune-mediated polyarthritis (IMPA) have neutrophilic inflammation in the synovial fluid. On the other hand, some dogs with erosive IMPA have increased mononuclear cells as the most abundant cell subset in the synovial fluid. A 9-year-old, neutered female miniature dachshund presented with lameness and lethargy. Physical examination revealed subluxation of the carpal and tarsal joints. Synovial fluid tests revealed an increased number of leukocytes, mainly mononuclear cells, and radiographic examination led to a diagnosis of erosive IMPA. Compared with nonerosive IMPA, flow cytometric analysis of the synovial fluid in this case showed a significant expansion of T cells-predominantly CD8⁺ cytotoxic T cells-while monocyte and B cell counts remained comparable. Treatment with mycophenolate mofetil reduced leukocytes in the synovial fluid and improved the dog's activity, although bone erosion slowly progressed. Based on these findings, we propose that T cells, especially cytotoxic T cells, in synovial fluid contribute to inflammation in canine erosive IMPA and may be a therapeutic target.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"9048633"},"PeriodicalIF":0.0,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13129212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous Melanoma in a Rabbit With Multiple Metastatic Lesions: A Case Report.","authors":"Amir Rostami, Hossein Aminianfar, Niloofar Zarifian, Nazanin Samiee, Ali Rahmanifar, Tarane Behniapour","doi":"10.1155/crve/8573115","DOIUrl":"10.1155/crve/8573115","url":null,"abstract":"<p><strong>Background: </strong>Neoplasia is increasingly common in senior pet rabbits, with cutaneous melanoma being a rare but aggressive type. Its characteristics in rabbits are not fully understood.</p><p><strong>Case description: </strong>A 5-year-old rabbit initially presented with a cutaneous mass at the ear base. Despite surgical excision, it recurred rapidly with multiple facial/chest masses and pulmonary metastases, leading to euthanasia. Pathological evaluation confirmed malignant melanoma, revealing features such as high mitotic activity and lymphovascular invasion; immunohistochemistry provided the definitive diagnosis.</p><p><strong>Conclusion and clinical relevance: </strong>This case highlights the highly aggressive and metastatic nature of cutaneous melanoma in rabbits, often resulting in a poor prognosis. Clinicians should be aware of melanoma's aggressive potential in rabbits. Surgical intervention alone may prove inadequate, and current treatment options in rabbits are limited. In this case, surgical intervention was not effective, likely because micrometastasis was already present. Treatment options remain limited, and euthanasia is often required in metastatic cases.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"8573115"},"PeriodicalIF":0.0,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13125338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Germline Pathogenic Variant in the APC Gene Suggestive of Gardner Syndrome in a Pony.","authors":"J Eric Martin, Silke Hecht, Linden Craig, Sian A Durward-Akhurst, Jillian L Marlowe, Melissa T Hines","doi":"10.1155/crve/1395580","DOIUrl":"10.1155/crve/1395580","url":null,"abstract":"<p><p>A 12-year-old pony mare was presented for evaluation of dental disease and nasal discharge. At presentation, clinical signs included bilateral nasal discharge, cutaneous masses, and numerous hard enlargements involving the bones of the skull, maxilla, mandible, and cervical vertebrae. Oral exam revealed advanced dental disease with hard enlargements adjacent to and between numerous cheek teeth. Radiographs and computed tomography confirmed the presence of severe dental disease and proliferative bone lesions disseminated along the skull, hyoid apparatus, and cranial cervical vertebrae. The bony proliferations extended into the subcutis, nasal cavity, paranasal sinuses, orbits, cranial vault, and vertebral canal. Multifocal osteomas were considered the primary differential, and this was confirmed on biopsy of a bony mass. Due to the extent of the lesions and deterioration of the patient's quality of life, euthanasia was elected. On necropsy, multiple osteomas were present on the skull and to a lesser extent the cervical vertebrae. Additional abnormalities included multiple mucosal polyps in the small intestine, epidermal inclusion cysts, and adrenocortical adenomas. These findings resemble those seen in Gardner syndrome, a hereditary disease of people characterized by gastrointestinal polyps and extraintestinal manifestations, including osteomas, epidermoid cysts, adrenal tumors, and dental abnormalities. Historically, Gardner syndrome in people has been considered a separate condition from familial adenomatous polyposis (FAP). Gardner syndrome is now considered a variant of FAP associated with mutations in the adenomatous polyposis coli (APC) gene. Whole genome sequencing and variant discovery in the pony identified multiple unique variants, including a likely pathogenic single base pair insertion leading to a frameshift in APC (ENSECAP00000007276.1:p.Glu1527ArgfsTer9). While osteomas have been infrequently reported in horses, to the authors' knowledge, there have been no cases of Gardner syndrome described in equids. This case is highly suggestive of Gardner-like syndrome in an equid.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"1395580"},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13108242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of a Patient-Specific 3D-Printed Splint for Surgical Correction of Pectus Excavatum in a Kitten.","authors":"Joana Reis, Kervin Ovalles, João Araújo, Fernando Silva, Rafael Coelho, Marco Gomes, José Simões","doi":"10.1155/crve/2686162","DOIUrl":"10.1155/crve/2686162","url":null,"abstract":"<p><p>Pectus excavatum is a rare congenital deformation of the chest wall. Associated clinical signs depend on the severity of the deformity of the sternum and costochondral cartilages. After thoracic radiographic studies, a patient-specific plastic external splint was designed based on a previously made plaster cast of the chest of the kitten. The splint was designed using 3D scan equipment and data processing to obtain the computer-aided model that was then used to manufacture the splint using 3D printing technology. The surgical application of the customized 3D-printed external splint for the correction of severe pectus excavatum in the young kitten was successful, with excellent tolerance observed postoperatively. After a period of 2 weeks, the splint was removed. Marked improvement of the sternum position was observed, and, more importantly, improvement in dyspnea and exercise intolerance was evident.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"2686162"},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Peritoneopericardial Diaphragmatic Hernia in a Dog: Ventral Advancement Diaphragmatic Technique for Repair.","authors":"Jonas D Perez-Bello","doi":"10.1155/crve/9977947","DOIUrl":"10.1155/crve/9977947","url":null,"abstract":"<p><p>Peritoneopericardial diaphragmatic hernia (PPDH) is a rare congenital anomaly that requires surgical treatment. Its clinical presentation varies and can affect one or more abdominal organs. This case report refers to a recently described surgical technique called ventral advancement of the diaphragm (VADT). Previously, a complete diagnostic approach was made in a 4-month-old, 6 kg (13.22 lbs.), uncastrated, mixed breed dog, with a history of cough from the time of adoption, with no known record of trauma. Physical examination revealed tachycardia, tachypnea, body condition score of 5/9, positivity to tracheal sensitivity tests, and attenuation of heart sounds in the left hemithorax, with no other relevant alterations. A PPDH was diagnosed and surgical correction was recommended. VADT was performed by incising the diaphragm ventrally with scissors, following the costal arch, about 3 cm on each side, avoiding excessive tension on the wound and possible postoperative dehiscence. Nonabsorbable monofilament material was used, with an interrupted horizontal suture pattern, without intraoperative or postoperative complications. The results showed that VADT is an easy surgical procedure to perform, being its approach beneficial for the patient, when compared with other techniques, providing an effective clinical resolution; generating little tension on the sutures that correct the diaphragmatic defect, with low rate of complications, dehiscence or recurrences, as reported in the literature and observed in this case. It is concluded that VADT is a surgical technique that is not very demanding for the surgical team and allows the defect to be corrected effectively, confirming its efficacy; however, further clinical evidence is recommended to validate its reproducibility.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"9977947"},"PeriodicalIF":0.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13090536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Correction of Pulmonary Stenosis Using Beating-Heart Cardiopulmonary Bypass in a Dog With Persistent Left Cranial Vena Cava.","authors":"Shuji Suzuki, Sachiyo Tanaka, Nobuo Kanno, Takuya Yogo, Yasuji Harada, Yasushi Hara","doi":"10.1155/crve/6139084","DOIUrl":"10.1155/crve/6139084","url":null,"abstract":"<p><p>A 7-month-old female toy poodle was referred for corrective surgery of pulmonary stenosis with persistent left cranial vena cava (PLCVC). Thoracic radiographs showed right heart enlargement. Echocardiography revealed moderate right ventricular hypertrophy and severe pulmonic stenosis with PLCVC. Right ventricular outflow tract reconstruction of severe pulmonary artery stenosis was performed under cardiopulmonary bypass. Intraoperative ventricular fibrillation occurred and was successfully treated with defibrillation; no postoperative complications were appreciated at the 1-month recheck. At the 6-month follow-up, the dog was in good general condition without exercise intolerance, and an echocardiogram revealed that the pulmonary artery velocity at the narrow area had decreased. This case suggests that surgical correction using cardiopulmonary bypass is a feasible treatment option for severe pulmonary stenosis with PLCVC, particularly in small dogs in which catheter-based intervention is technically challenging.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"6139084"},"PeriodicalIF":0.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attenuation of Ascites Following Surgical Ligation of a Congenital Caudal Mesenteric Arteriovenous Fistula in a Dog.","authors":"Shuji Suzuki, Sachiyo Tanaka, Nobuo Kanno, Takuya Yogo, Yasuji Harada, Masaki Michishita, Yasushi Hara","doi":"10.1155/crve/8275438","DOIUrl":"10.1155/crve/8275438","url":null,"abstract":"<p><p>A 1-year-and-9-month-old intact female Pembroke Welsh Corgi (10.5 kg) was referred for abdominal distension, intermittent diarrhea, and ascites. Abdominocentesis yielded 1200 mL of transudate (specific gravity, 1.008). Serum biochemistry showed hyperammonemia (NH₃, 163 <i>μ</i>g/dL), increased bile acids, and mild hypoalbuminemia. Abdominal ultrasonography suggested a vascular anomaly, and contrast-enhanced computed tomographic angiography confirmed an arteriovenous communication between the caudal mesenteric artery and vein with marked venous dilation and multiple acquired portosystemic shunts, consistent with portal hypertension secondary to a congenital caudal mesenteric arteriovenous fistula. Surgical ligation was performed via ventral midline celiotomy. Portal venous pressure measured via a mesenteric vein decreased from 23/20 (21) mmHg to 19/16 (17) mmHg after occlusion; a 5-min test occlusion caused no gross intestinal congestion. Liver biopsy revealed portal vein hypoplasia with reduced portal triads. Ascites resolved by Postoperative Day 3, and the dog was discharged on Postoperative Day 6 (Day 22). Ascites recurred on Day 868, but follow-up computed tomography on Day 1191 confirmed persistent occlusion of the fistula. Under adjunct medical management, the dog remained clinically stable with only mild hyperammonemia (NH₃, 132 <i>μ</i>g/dL). This case suggests that surgical ligation can reduce portal hypertension and resolve ascites in dogs with caudal mesenteric arteriovenous fistulas, although long-term monitoring may be required.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"8275438"},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13086555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}