Case Reports in Veterinary Medicine最新文献

{"title":"French Bulldog Diagnosed With a Suspected Brain Tumor Shortly After Treatment for Spinal Arachnoid Diverticulum.","authors":"Yuya Nakamoto, Kyosuke Hidari, Mei Matsuo, Miwa Nakamoto","doi":"10.1155/crve/8302806","DOIUrl":"10.1155/crve/8302806","url":null,"abstract":"<p><p>An 8-year- and 8-month-old spayed female 8.8-kg French bulldog presented with a 4-month history of progressive deterioration, followed by paresis of both pelvic limbs. Orthopedic examination revealed no abnormalities. Neurological examination revealed no findings suggestive of brain dysfunction. However, abnormal findings, including impaired conscious proprioception in both pelvic limbs and hyperreflexia of patellar, cranial tibialis, and gastrocnemius reflexes, suggested a spinal segmental lesion in the T3-L3 region. The dog was diagnosed with a spinal arachnoid diverticulum in the T11-T12 vertebrae (Day 1) by magnetic resonance imaging (MRI) and underwent surgical treatment (dorsal laminectomy with dural marsupialization) on Day 27. The dog was presented to the referral hospital on a weekly basis and underwent neurological examinations at each visit. Initial neurological signs included persistent bilateral pelvic limb proprioceptive deficits; no other new neurological abnormalities were noted. Epileptic seizures occurred on Days 43 and 57. Brain MRI performed on Day 91 revealed findings suggestive of a glioma. The dog was administered prednisone (0.5 mg/kg SID, PO) and zonisamide (5 mg/kg BID, PO). Neurological abnormalities, such as circling and left forelimb ambulatory monoparesis, became more noticeable. The dog developed status epilepticus and died on Day 209. The owner said that the frequency of seizures was approximately twice a month and had not increased, and seizure duration did not appear to have lengthened until Day 209. In this case, no direct history or neurological abnormalities suggestive of a lesion in the forebrain region were noted until the onset of epileptic seizures; however, the glioma was diagnosed within 3 months of spinal arachnoid diverticulum diagnosis. Therefore, the brain tumor might have been detected if a brain MRI had been performed when spinal cord disease was initially diagnosed. This report indicates that simultaneous brain MRIs should be considered when performing MRI examinations for spinal cord diseases. However, this report describes a single case and lacks a histopathological evaluation for a definitive diagnosis of glioma, meningioma, or other types of brain tumors.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"8302806"},"PeriodicalIF":0.0,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Septic Endophthalmitis Following Suprachoroidal Cyclosporine Implant Placement in Two Horses With Equine Recurrent Uveitis.","authors":"Milena Sanchez-Garcia, Ria Chalder, Ben Blacklock, Claudia Hartley, Emma Scurrell, Rachel Neto, David Sutton, Richard J McMullen","doi":"10.1155/crve/7378792","DOIUrl":"10.1155/crve/7378792","url":null,"abstract":"<p><p>This article presents the clinical and histopathological findings from two horses that developed severe postoperative complications following suprachoroidal procedures routinely employed in the management of equine recurrent uveitis (ERU). Case 1 was a 5-year-old warmblood stallion that initially received a unilateral suprachoroidal triamcinolone injection, followed later by bilateral suprachoroidal cyclosporine implant (CSI) placement. At 9 weeks postoperatively, the right eye (which had undergone both procedures) developed secondary glaucoma necessitating enucleation. Case 2 was a 14-year-old Appaloosa mare that presented 9 days postoperatively with suspected bilateral CSI rejection. Due to poor visual prognosis, the horse was euthanized. Histopathologic examination of all three affected globes demonstrated findings consistent with severe, suppurative endophthalmitis of bacterial etiology.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"7378792"},"PeriodicalIF":0.0,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148449755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transnasal Esophagorumenoscopy and Laparoscopic Assisted Rumenostomy in a Cow With Digestive Distress-Case Report.","authors":"Luiz Henrique Vilela Araújo, Luis Gustavo E Silva Novais, Thiago da Silva Cardoso, Lucas Santos Carvalho, Pedro Henrique Lira Cerqueira, José Leandro da Silva Gonçalves, André de Medeiros Costa Lins, Tatiane Teles Albernaz Ferreira, José Alcides da Silveira, Marco Duarte Dutra, Felipe Masiero Salvarani, Francisco Décio de Oliveira Monteiro, Pedro Paulo Maia Teixeira","doi":"10.1155/crve/8183318","DOIUrl":"10.1155/crve/8183318","url":null,"abstract":"<p><p>A Girolando cow presented with signs suggestive of esophageal obstruction. The team performed diagnostic and therapeutic procedures. Transnasal esophagorumenoscopy with a flexible gastroscope revealed hyperemic erosions and later foamy ulcers in the esophageal mucosa, but no obstructive foreign body. Laparoscopic-assisted rumenostomy via a two-port technique identified intraperitoneal adhesions and ruminal impaction. Under laparoscopic guidance, we placed and secured a handmade cannula fashioned from a 10-mm cuffed endotracheal tube to the abdominal wall. This provided access for therapeutic transfaunation and fluid administration, facilitating short-term clinical stabilization. However, the cow ultimately died due to complications from traumatic reticuloperitonitis caused by a perforating metallic foreign body, leading to diffuse peritonitis and aspiration pneumonia, as confirmed by necropsy. The primary sequelae were diffuse peritonitis and aspiration pneumonia, the latter likely secondary to the esophageal dysfunction and/or therapeutic intervention, as confirmed by necropsy. Despite the fatal outcome, transnasal endoscopy offered valuable real-time assessment of esophageal integrity, and the laparoscopic-assisted placement of a ruminal cannula proved to be a functional, minimally invasive therapeutic alternative. This case illustrates the combined utility of these endoscopic techniques for diagnosing and managing complex digestive distress in cattle, while highlighting their limitations in reversing severe, established pathology.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"8183318"},"PeriodicalIF":0.0,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12969214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcoma at the Site of a Transponder Implant in a Standing's Day Gecko (<i>Phelsuma standingi</i>): A Case Report.","authors":"Madeleine V Thompson, Tessa Kell, Stefan M Keller, Jasmine Rosario, Jenessa Gjeltema","doi":"10.1155/crve/1376178","DOIUrl":"10.1155/crve/1376178","url":null,"abstract":"<p><p>A 26-year-old female Standing's day gecko (<i>Phelsuma standingi</i>) was presented for evaluation of a mass on the right caudolateral trunk and was subsequently euthanized. Necropsy revealed a neoplastic mass surrounding a passive integrated transponder at the body wall. Histopathology of the mass was consistent with a sarcoma and was characterized by whorls of fusiform neoplastic cells invading the muscle, adipose, and bone of the coelomic wall. Given its proximity to the transponder and the degree to which it encompassed the device, the sarcoma was inferred to be transponder-associated. However, further conclusions regarding a causal relationship between the transponder implant and the neoplastic mass cannot be drawn based on this single case. This report describes the clinical presentation and pathologic findings for a microchip-associated neoplasia in a reptile.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"1376178"},"PeriodicalIF":0.0,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12956844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147366598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Atypical Myelomonocytic Leukemia of Eosinophilic Lineage in a Cat With Feline Leukemia Virus: A First Case Report.","authors":"Morales Orozco Pablo José, Magaña Anzaldo Aida Evelyn, Bernal Muñoz Diana Betsabe, Saavedra Ruvalcaba Adolfo Giovanni, Rosales Camacho Paulina","doi":"10.1155/crve/6729159","DOIUrl":"10.1155/crve/6729159","url":null,"abstract":"<p><p>Feline hematopoietic neoplasms associated with retroviruses pose a diagnostic and therapeutic challenge, especially when they present with atypical morphological features that do not fit conventional classifications. This work describes the first reported case worldwide of atypical chronic myelomonocytic leukemia of eosinophilic lineage in a cat positive for feline leukemia virus, diagnosed through detailed cytomorphological analysis and the use of enzymatic cytochemical stains. The rarity of this case underscores the importance of documenting and studying uncommon presentations, with the goal of expanding clinical knowledge and strengthening diagnostic tools in feline veterinary medicine.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"6729159"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12940797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147327651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphocytosis and Mycobacteriosis in a 15-Year-Old Mixed-Breed Dog.","authors":"Bridgette J Murphy, Ashley A Smith, Erin M Kilbane, Francisco O Conrado","doi":"10.1155/crve/5288911","DOIUrl":"10.1155/crve/5288911","url":null,"abstract":"<p><p>A 15-year-old mixed-breed dog with T-cell lymphoid neoplasia with persistent CD8⁺ lymphocytosis and peripheral lymphadenopathy despite chemotherapy was referred to the Auburn University Veterinary Teaching Hospital Oncology service approximately 7 months after diagnosis. Lymph node aspirates were performed and assessed by a board-certified clinical pathologist, which revealed granulomatous inflammation and intracellular, negative staining bacilli. Bacilli were confirmed <i>Mycobacterium avium</i> and other species within the <i>M. avium</i> complex by polymerase chain reaction (PCR) testing. Chemotherapy was ceased and antimicrobial therapy was initiated; however, the lymphocytosis continued to progress, and the dog began to decline, leading to euthanasia around 2 months after referral. Although T-cell lymphoid neoplasia and mycobacteriosis are rare comorbidities, this case highlights the importance of thorough cytological assessment of lymph node aspirates as part of a complete workup to rule out differential causes of lymphadenopathy. This may have allowed for earlier diagnosis and treatment of mycobacteriosis.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"5288911"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12940798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147327621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pityriasis Versicolor in a Southern Ground Hornbill (<i>Bucorvus leadbeateri</i>).","authors":"Gonçalo N Marques, Miguel Lourenço, Miriam Leal, Nuno Urbani, Maria Conceição Peleteiro","doi":"10.1155/crve/5261490","DOIUrl":"10.1155/crve/5261490","url":null,"abstract":"<p><p>A 20-year-old southern ground hornbill (<i>Bucorvus leadbeateri</i>) developed hyperpigmented macules on its gular pouch, resembling the lesions typically seen in humans with pityriasis versicolor. Cytologic examination revealed over 100 budding yeasts per oil immersion field. Fungal culture showed rare growth of smooth, cream-colored yeast colonies, identified by PCR as <i>Malassezia slooffiae</i>. Histopathological analysis showed lymphocytic perivascular dermatitis. Periodic acid-Schiff staining revealed rare forms of yeasts between the layers of the stratum corneum. This clinical report provides further insights into the role of <i>Malassezia</i> spp. in the avian skin microbiome. To the authors' knowledge, this is the first report of <i>Malassezia</i> sp. as an agent of pityriasis versicolor in birds.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"5261490"},"PeriodicalIF":0.0,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12927905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Hepatic Hemangiosarcoma With Hemoperitoneum in a Dog: Clinical Course and Therapeutic Outcome.","authors":"Myeong-Yeon Lee, Jong-Hyun Moon, Jinsu Mok, Dowoo Lim, Ju-Yeong Kim, Seo-Yeong Jung, Eunbin Jeong, Hyomi Jang, Dong-In Jung","doi":"10.1155/crve/8709546","DOIUrl":"10.1155/crve/8709546","url":null,"abstract":"<p><p>A 14-year-old neutered male mixed-breed dog presented with hemoperitoneum secondary to rupture of a primary hepatic mass. Following stabilization with whole blood transfusion, a hepatic lobectomy was performed. Histopathological examination and CD31 immunolabeling confirmed a diagnosis of hemangiosarcoma. Two weeks postoperatively, multiple intra-abdominal metastases were identified. The multimodal therapeutic approach included one attempted VAC cycle (discontinued due to Grade 4 neutropenia), five cycles of single-agent doxorubicin, and subsequent administration of toceranib with dose reduction for anemia. The dog survived 201 days after diagnosis. Postmortem extended immunohistochemistry demonstrated heterogeneous receptor tyrosine kinase (RTK) expression: EGFR and VEGFR positivity, strong membranous HER2 labeling in approximately 60% of tumor cells, low KIT expression, and negative PDGFR. This case underscores the aggressive metastatic nature of primary hepatic hemangiosarcoma following rupture and highlights practical considerations for systemic therapy selection and adverse event monitoring in clinical practice.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"8709546"},"PeriodicalIF":0.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12848542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146087276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cautionary Tale of <i>Exophiala spinifera</i> Infection in Two Cats: Case Reports and Literature Review.","authors":"Maryann D Makosiej, Stephanie Anderson, Mandy A Womble, Ashley Parsley, Hiroyuki Mochizuki, Petra Bizikova, Tim Chan, Ramón M Almela, Laura M Ribas, Lina C Bilhalva, Andrea P Santos, Fábio Brum-Rosa, Danielle Meritet, Francisco O Conrado","doi":"10.1155/crve/5572312","DOIUrl":"10.1155/crve/5572312","url":null,"abstract":"<p><p>This case series reports two independent cases of <i>Exophiala spinifera</i> infection in adult male neutered domestic cats, both referred following misdiagnosis. To date, only six cases associated with this organism have been reported in domestic cats, excluding those described herein. These also represent the first documented cases of <i>E. spinifera</i> infection in cats in the United States. In both cases, a definitive etiologic diagnosis could not be made by cytology, histology, or fungal culture. Moreover, histologic features did not allow for clear classification of the lesions as phaeohyphomycosis or chromoblastomycosis. Ultimately, accurate identification of the fungal pathogen was achieved through molecular diagnostic testing, rather than conventional mycologic or microscopic methods. These cases underscore the importance of molecular diagnostics and inter-institutional collaboration in the accurate identification of dematiaceous fungi, such as <i>E. spinifera</i>, particularly given their variable clinical and pathological presentations.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"5572312"},"PeriodicalIF":0.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12779925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145952807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Bacterial Septicemia in a Critically Endangered Roloway Monkey in a Primate Breeding Center at the Accra Zoological Garden, Ghana: A Case Report.","authors":"Richard Suu-Ire, Henry Abugri, Samuel Asumah, Richard Abbiw, David Turkson, Mustapha Ahmed, Peter Gathumbi","doi":"10.1155/crve/4924170","DOIUrl":"10.1155/crve/4924170","url":null,"abstract":"<p><p>This case report explains the cause of death of a roloway monkey (<i>Cercopithecus roloway</i>), a critically endangered primate native to the Upper Guinea forests of West Africa, that was kept for captive breeding and conservation at the Accra Zoological Garden's primate breeding center in Ghana. <i>Sweetpea</i>, a \"15-year-old\" female Roloway monkey, was found dead on September 21, 2018, without prior signs of illness. Gross and histopathological findings revealed acute fibrinous pneumonia, septicemia, and myocardial necrosis, while bacterial culture of lung tissue and thoracic fluid yielded <i>β</i>-hemolytic <i>Streptococcus</i> spp., implicating it as the likely cause of death. Whereas species-level identification was not performed due to resource limitations, isolation of this species in pure culture supports its implication in this case, leaning on the published knowledge of its primary role in bacterial septicemia and pneumonia and other soft tissue infections in monkeys, even in captivity. Roloway monkeys (<i>Cercopithecus roloway</i>) are critically endangered primates native to the Upper Guinea forests of West Africa. This report describes the sudden death of a 15-year-old female at the Accra Zoological Garden and the subsequent diagnostic investigation, which revealed <i>β</i>-hemolytic <i>Streptococcus</i> spp. as the causative agent of acute pneumonia and septicemia. This case underscores the need for structured health monitoring in captive breeding programs and highlights veterinary and husbandry measures crucial to conservation efforts. Additionally, a uterine leiomyosarcoma was detected, which may explain Sweetpea's failure to reproduce despite long-term pairing. This case highlights the importance of surveillance for beta-hemolytic streptococci in captive monkeys, more so the endangered species.</p>","PeriodicalId":37339,"journal":{"name":"Case Reports in Veterinary Medicine","volume":"2026 ","pages":"4924170"},"PeriodicalIF":0.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12775829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}