{"title":"Dynamic left ventricular outflow tract obstruction induced by intra-aortic balloon pump in patient with angioedema.","authors":"Konstantin Yastrebov, Gregory Cranney","doi":"10.1186/s13089-025-00426-4","DOIUrl":"10.1186/s13089-025-00426-4","url":null,"abstract":"<p><strong>Background: </strong>Intra-aortic balloon pump is used for temporary mechanical support of failing left ventricle. It works by reducing the arterial afterload during ventricular systole to reduce myocardial work and increasing diastolic proximal aortic pressure to improve coronary perfusion. Rarely, intra-aortic balloon pump (IABP) can become the cause of severe haemodynamic compromise, causing dynamic left ventricular outflow tract obstruction.</p><p><strong>Case presentation: </strong>An 88-yo man presented with angiotensin converting enzyme inhibitor (ACEI) - induced angioedema. He received steroids and adrenaline, but progressed to the respiratory arrest, requiring emergency awake fiberoptic intubation and mechanical ventilation. Echocardiography revealed catecholamine-induced reversed Takotsubo cardiomyopathy. The patient suffered asystolic cardiac arrest on arrival to intensive care unit (ICU), requiring cardiopulmonary resuscitation (CPR). Bradycardia and hypotension were treated with atrial pacing and (IABP). Icatibant was administered for angioedema. After several hours of haemodynamic stability, severe hypotension returned. Bedside echocardiographic diagnosis of recovery from Takotsubo and new development of IABP-induced dynamic left ventricular outflow tract obstruction (DLVOTO) was made. Stopping IABP resulted in rapid haemodynamic recovery. Repeated doses of Icatibant were needed. The patient survived and returned to independent living.</p><p><strong>Conclusions: </strong>Immediate echocardiographic recognition of iatrogenic DLVOTO caused by IABP allows discontinuation of IABP support as a life-saving intervention. Dynamic application of spectral Doppler with changes in IABP settings is required for correct diagnosis.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"22"},"PeriodicalIF":3.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peripheral nerve ultrasound: a survival guide for the practicing radiologist with updates.","authors":"Mohamed Ragab Nouh, Hoda Mohamed Abdel-Naby, Tarek El Sakka, Mohamed El-Shafei","doi":"10.1186/s13089-024-00387-0","DOIUrl":"10.1186/s13089-024-00387-0","url":null,"abstract":"<p><p>Peripheral nerve injuries negatively impact patients' quality of life and healthcare resources. This review discusses using high-resolution neurosonography (HRNUS) for mapping peripheral nerves and detecting pathologic lesions. It emphasizes the importance of HRNUS in diagnosing nerve disorders and briefs the widely accepted schemes for peripheral nerve injury classification. It also highlights the non-intrusive, flexible, patient-friendly, and cost-effective nature of HRNUS, making it a valuable tool in managing nerve disorders. The authors recommend the use of HRNUS to enable precise diagnoses, prevent permanent disabilities, and contribute to the efficient utilization of healthcare resources.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"21"},"PeriodicalIF":3.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Konstantin Warneke, Stanislav D Siegel, Jonas Drabow, Lars H Lohmann, Daniel Jochum, Sandro R Freitas, José Afonso, Andreas Konrad
{"title":"Examiner experience moderates reliability of human lower extremity muscle ultrasound measurement - a double blinded measurement error study.","authors":"Konstantin Warneke, Stanislav D Siegel, Jonas Drabow, Lars H Lohmann, Daniel Jochum, Sandro R Freitas, José Afonso, Andreas Konrad","doi":"10.1186/s13089-025-00424-6","DOIUrl":"10.1186/s13089-025-00424-6","url":null,"abstract":"<p><p>Structural muscle properties are critical in health and athletic settings, with magnetic resonance imaging considered the gold standard assessment procedure under static conditions due to its reliability and objectivity. Practical limitations, including cost and accessibility, have led to the increasing use of ultrasound as an alternative for skeletal muscle morphological parameters. However, ultrasound measurements are sensitive to evaluation conditions and assessor experience, which has not been sufficiently explored, yet. Therefore, this study investigated the influence of assessor experience on the reliability of ultrasound measurements. A double-blind design was used, involving an experienced assessor (> 12,000 images for several years) and multiple inexperienced assessors (< 100 images) to collect data from 39 recreationally active participants. Measurements of muscle architecture were conducted in the leg muscles over two consecutive days, generating 1,248 ultrasound images. Relative and absolute reliability were analyzed using intraclass correlation coefficients (ICCs), standard error of measurement, minimal detectable change, mean absolute error (MAE), mean absolute percentage error (MAPE) and Bland-Altman analyses. Relative reliability was good to excellent in all measurement spots and time-points for muscle thickness (ICC = 0.76-0.98) irrespective of assessor experience, except for the inter-day comparison for the gastrocnemius lateralis by the inexperienced assessors, (ICC = 0.58). The pennation angle assessment ranged from insufficient to excellent reliability (ICC = 0.18-0.94) and experience contributed greatly to better results. The random error for the inexperienced assessors was reflected in two- to three-times higher MAEs/MAPEs and limits of agreement in the Bland-Altman analyses, respectively. The findings emphasize the importance of experience and standardization in achieving reliable ultrasound data, particularly for (a) sensitive parameters like the pennation angle and/or (b) inter-day, intra-subject comparisons.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"20"},"PeriodicalIF":3.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound-guided vs. Non-ultrasound-guided femoral artery puncture techniques: a comprehensive systematic review and meta-analysis.","authors":"Yi-Chen Huang, Yueh-Hsun Lu, Wei-Yi Ting","doi":"10.1186/s13089-025-00422-8","DOIUrl":"10.1186/s13089-025-00422-8","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the effectiveness of ultrasound-guided (US) versus non-US femoral artery puncture (FAP) methods, including fluoroscopy-guided (FL) and non-guided (NG) techniques.</p><p><strong>Materials: </strong>This meta-analysis included 11 randomized controlled trials and 1 non-randomized retrospective study, comprising a total of 12 studies involving 5534 patients across diverse clinical settings. Studies varied in operator experience, institutional settings, and procedural protocols. Key outcomes assessed included complication rates, vessel access time, first-pass success rates, number of attempts, and the risk of accidental venipuncture.</p><p><strong>Results: </strong>Analysis of the heterogeneous dataset showed that guided techniques were associated with reduced complication rates compared to NG methods (pooled odds ratio (OR): 0.45, 95% Confidence Interval (CI) 0.28-0.73). US guidance was associated with decreased vessel access time (mean difference: - 16.30 s, 95% CI - 29.83 to - 2.76), higher first-pass success rates (pooled OR: 3.54, 95% CI 2.36 to 5.30), and required fewer attempts compared to non-US techniques. US guidance also showed lower risk of inadvertent venipuncture (pooled OR: 0.22, 95% CI 0.14 to 0.34).</p><p><strong>Conclusion: </strong>This meta-analysis suggests potential benefits of US femoral artery puncture techniques over non-US methods, while acknowledging significant heterogeneity across studies. The observed advantages in procedural outcomes varied across different clinical settings and operator experience levels. These findings provide setting for institutional decision-making regarding the implementation of guided puncture methods, considering factors such as operator expertise, resource availability, and specific patient populations.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"19"},"PeriodicalIF":3.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11885736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephan Katzenschlager, Thomas Hamp, Maximilian Dietrich, Christopher T Edmunds, Nikolai Kaltschmidt, Markus A Weigand, Mario Krammel, Frank Weilbacher, Erik Popp
{"title":"Assess, improve, detect, guide: a narrative review and proposal for a standardized protocol for prehospital transesophageal echocardiography during out-of-hospital cardiac arrest.","authors":"Stephan Katzenschlager, Thomas Hamp, Maximilian Dietrich, Christopher T Edmunds, Nikolai Kaltschmidt, Markus A Weigand, Mario Krammel, Frank Weilbacher, Erik Popp","doi":"10.1186/s13089-025-00418-4","DOIUrl":"10.1186/s13089-025-00418-4","url":null,"abstract":"<p><p>While there are different protocols for in-hospital transesophageal echocardiography, there is no existing protocol for prehospital usage during out-of-hospital cardiac arrest. Herein, the \"assess-improve-detect-guide\" protocol is described. This protocol includes four mid-esophageal views to address the most time-sensitive aspects during out-of-hospital cardiac arrest. This protocol can be used in services with and without the capability for eCPR, with the benefit of profiting from additional diagnostic and personal resources. This protocol provides a standardized approach for performing transesophageal echocardiography during out-of-hospital cardiac arrest and reporting the results.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"18"},"PeriodicalIF":3.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafael Hortêncio Melo, Luciana Gioli-Pereira, Edielle Melo, Philippe Rola
{"title":"Venous excess ultrasound score association with acute kidney injury in critically ill patients: a systematic review and meta-analysis of observational studies.","authors":"Rafael Hortêncio Melo, Luciana Gioli-Pereira, Edielle Melo, Philippe Rola","doi":"10.1186/s13089-025-00413-9","DOIUrl":"10.1186/s13089-025-00413-9","url":null,"abstract":"<p><strong>Background: </strong>Systemic venous congestion assessed by the venous excess ultrasound score (VExUS), has been associated with acute kidney injury (AKI) in patients undergoing cardiac surgery. However, there is a lack of evidence of this association in the general critically ill patients.</p><p><strong>Study design and methods: </strong>PubMed, Embase, and Cochrane databases were searched for observational prospective studies that included critically ill patients and analyzed VExUS score on the first day of admission to the ICU. The main outcome was occurrence of AKI. Secondary outcome was all-cause mortality. Statistical analysis was performed using Review Manager 5.4.1. Odds ratios (OR) with 95% confidence interval were pooled using a random-effects model. The Quality in Prognosis Studies (QUIPS) tool was used to assess risk of bias. Publication bias was assessed via funnel plot and heterogeneity was examined with I<sup>2</sup> statistics.</p><p><strong>Results: </strong>Our analysis included 1036 patients from nine studies, of whom 17.4% presented venous congestion according to VExUS definition. In critically ill patients presenting with venous congestion (VExUS score ≥ 2), the incidence of AKI was significantly higher as compared with those without congestion (OR 2.63, 95% CI 1.06-6.54; p = 0.04; I<sup>2</sup> = 74%). The association was notably stronger in cardiac surgery patients (OR 3.86, 95% CI 2.32-6.42; p < 0.00001; i<sup>2</sup> = 0%). There was no significant association between venous congestion and all-cause mortality (OR 1.25, 95% CI 0.71-2.19; p = 0.44; i<sup>2</sup> = 8%).</p><p><strong>Conclusions: </strong>These findings suggest that VExUS score may correlate with an elevation in the incidence AKI in critically ill patients, with a more pronounced effect observed within the subgroup of patients undergoing cardiac surgery. There was no statistically significant association between VExUS score and all-cause mortality.</p><p><strong>Clinical trial registration: </strong>PROSPERO under protocol number CRD535513.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"16"},"PeriodicalIF":3.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and utilization of obstetric ultrasound and associated factors among pregnant mother in Africa: a systematic review and meta-analysis.","authors":"Anteneh Gashaw, Zerihun Figa, Yonas Abebe, Abel Desalegn Demeke, Yohanes Sime","doi":"10.1186/s13089-025-00420-w","DOIUrl":"10.1186/s13089-025-00420-w","url":null,"abstract":"<p><strong>Background: </strong>Obstetric ultrasound (US) is a non-invasive imaging method that employs sound waves to explore the abdominal and pelvic areas of a pregnant woman. It is recommended to have at least two ultrasound scans during pregnancy, one in the first trimester and another in the second trimester, to identify potential complications and improve perinatal outcomes. While this practice is widely implemented in developed nations, its utilization in many African countries remains suboptimal. This systematic review and meta-analysis aims to examine the level of knowledge and utilization of obstetric ultrasound among pregnant women in Africa, providing insights into its awareness and utilization across the continent.</p><p><strong>Method: </strong>A systematic review and meta-analysis were conducted following PRISMA guidelines. Extensive literature searches were carried out across various databases, including PubMed, Google Scholar, ScienceDirect, Web of Science, Scopus, and African Online Journal databases. The pooled prevalence was estimated using a weighted inverse variance random-effects model. Heterogeneity among studies was assessed using the Cochrane Q-test and I<sup>2</sup> statistics, while publication bias was evaluated through a funnel plot and Egger's test. Stata v17 software was employed to analyze factors associated with the utilization of obstetric ultrasound among pregnant women in Africa.</p><p><strong>Result: </strong>A total of 622 articles were initially identified, with 23 ultimately meeting the inclusion criteria for this review, including five studies that addressed both knowledge and utilization of obstetric ultrasound. The overall knowledge level among pregnant women in Africa regarding obstetric ultrasound was estimated at 74.33% (95% CI 63.27-85.38%), while the pooled proportion of utilization was 63.3% (95% CI 51.59-75.02%). Subgroup analysis revealed that both knowledge and utilization levels were highest in Western Africa, whereas knowledge was lowest among pregnant women in Eastern Africa. Pregnant women with good knowledge of obstetric ultrasound were significantly more likely to utilize the service, with a pooled odds ratio (POR) of 8.41 (95% CI 4.66-12.16).</p><p><strong>Conclusion: </strong>This systematic review and meta-analysis revealed a moderate utilization of obstetric ultrasound among pregnant mothers in Africa, with an increasing trend over time, particularly after 2020. The overall level of knowledge about obstetric ultrasound among mothers was 74.33%, and knowledge was identified as the key factor significantly associated with ultrasound utilization.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"17"},"PeriodicalIF":3.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Ruste, Quentin Delas, Rehane Reskot, Jean-Luc Fellahi, Matthias Jacquet-Lagrèze
{"title":"Relationship between point-of-care ultrasound venous congestion assessment parameters, intravenous pressure, and venous return: a post-hoc analysis of a prospective cohort study.","authors":"Martin Ruste, Quentin Delas, Rehane Reskot, Jean-Luc Fellahi, Matthias Jacquet-Lagrèze","doi":"10.1186/s13089-025-00421-9","DOIUrl":"10.1186/s13089-025-00421-9","url":null,"abstract":"<p><strong>Background: </strong>A recent study suggested that point-of-care ultrasound (POCUS) venous congestion assessment poorly describes the changes in venous return during a fluid challenge. The aim of the present study was to explore the relationship between POCUS venous congestion assessment parameters and the determinants of venous return in steady state and during a fluid challenge.</p><p><strong>Methods: </strong>This study is a post-hoc analysis of a single-centre prospective cohort study of patients presenting acute circulatory failure and venous congestion. The protocol consisted in a fluid administration of 4mL/kg over five minutes, just preceded and followed by the acquisition of haemodynamic data and POCUS venous congestion assessment parameters (VExUS score and portal pulsatility index, PPi). Venous return (dVR) was defined as the difference between mean systemic filling pressure analogue estimated by the mathematical approach of Parkin and Leaning (Pmsa) and central venous pressure (CVP). Relationships between Pmsa, CVP, dVR, and VExUS score and PPi were analysed using linear regression and Jonckheere-Terpstra test for trend.</p><p><strong>Results: </strong>Thirty-two patients were included in the analysis. Fluid challenge induced a significant increase in CVP, Pmsa, dVR, and VExUS score. In steady state, there was a significant association of VExUS score and PPi with CVP (P-value = 0.006 and 0.002, respectively) and Pmsa (P-value = 0.004 and 0.003, respectively) but not with dVR (P-value = 0.943 and 0.408, respectively). The variations induced by fluid challenge in CVP, Pmsa and dVR were not associated with variations in PPi (P-value = 0.844, 0.912 and 0.716, respectively). Patients without VExUS score increase during the fluid challenge presented a higher increase in Pmsa than patients with an increase in VExUS score.</p><p><strong>Conclusion: </strong>In steady state, POCUS venous congestion assessment parameters are associated with CVP and Pmsa but not with dVR. After fluid administration, changes in POCUS venous congestion assessment parameters were not associated with changes in CVP, Pmsa, and dVR.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"15"},"PeriodicalIF":3.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun Wang, Christopher G Scott, Garvan C Kane, Sorin V Pislaru, Jared G Bird, Patricia A Pellikka, Vidhu Anand
{"title":"One size doesn't fit all: exploring the influence of body size, age, and sex on right ventricle size measurements.","authors":"Yun Wang, Christopher G Scott, Garvan C Kane, Sorin V Pislaru, Jared G Bird, Patricia A Pellikka, Vidhu Anand","doi":"10.1186/s13089-025-00407-7","DOIUrl":"10.1186/s13089-025-00407-7","url":null,"abstract":"<p><strong>Background: </strong>The assessment of right ventricular (RV) size is an important part of 2-dimensional transthoracic echocardiography. Current chamber quantification guidelines provide reference values as unindexed numbers, similar for men and women. We sought to evaluate normal ranges of RV dimensions based on age, sex, body surface area (BSA), and height. Consecutive patients with \"normal echocardiogram\" between January 2011 and August 2022 at our center were retrospectively included. RV dimensions including diameter at the base and mid-ventricle level, and base-to-apex length were measured.</p><p><strong>Results: </strong>Of 1389 patients (median 43 years, 53% female) with all three measurements available, the median RV measurements, both unindexed and indexed to BSA, were: basal diameter 35.0 mm (31.0-39.0) and 18.4 mm/m<sup>2</sup> (16.5-20.3); mid diameter 28.0 mm and 14.8 mm/m<sup>2</sup> (13.1-16.6); RV length 73.0 mm (67.0-78.0) and 37.6 mm/m<sup>2</sup> (34.9-40.9). RV dimensions were larger in men than women across all age groups but similar when indexed to BSA (for basal and mid dimensions). RV length was best indexed to height. Our indexed normal values by age and sex were similar to World Alliance Societies of Echocardiography (WASE) cohort.</p><p><strong>Conclusions: </strong>RV measurements should be indexed to BSA, considering sex and age, to determine RV size and enlargement.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"14"},"PeriodicalIF":3.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan M Fernandez, Carmen Rosa Hernández-Socorro, Lucas Omar Robador, Francisco Rodríguez-Esparragón, Daniela Medina-García, Juan Carlos Quevedo-Reina, Mercedes Lorenzo-Medina, Elena Oliva-Dámaso, Patricia Pérez-Borges, José C Rodríguez-Perez
{"title":"Ultrasound versus magnetic resonance imaging for calculating total kidney volume in patients with ADPKD: a real-world data analysis.","authors":"Juan M Fernandez, Carmen Rosa Hernández-Socorro, Lucas Omar Robador, Francisco Rodríguez-Esparragón, Daniela Medina-García, Juan Carlos Quevedo-Reina, Mercedes Lorenzo-Medina, Elena Oliva-Dámaso, Patricia Pérez-Borges, José C Rodríguez-Perez","doi":"10.1186/s13089-025-00400-0","DOIUrl":"10.1186/s13089-025-00400-0","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to compare Total kidney volume (TKV) measurements using US-ellipsoid (US-EL) and MRI-ellipsoid (MRI-EL) in patients with autosomal-dominant-polycystic-kidney-disease (ADPKD). It also evaluated whether the agreement between right (RKV) and left (LKV) kidney volume measurements differed.</p><p><strong>Methods: </strong>Retrospective analysis of a prospective data-base that included consecutive patients diagnosed with ADPKD. Total kidney volumes by 3D-US-EL were compared with those by MRI-EL. Bland-Altman-plots, Passing-Bablok-regression, and the concordance-correlation-coefficient (CCC) were used to compare right (RKV), left (LKV), and TKV measurements.</p><p><strong>Results: </strong>Thirty-two ADPKD patients, 14(43.7%) women, were included. Mean measured (mGFR) and estimated (eGFR) glomerular-filtration-rate (GFR) were 86.5 ± 23.9 mL/min and 78.9 ± 23.6 mL/min, respectively. Compared with MRI-EL, TKV (Mean difference: - 85.9 ± 825.6 mL; 95%CI - 498.5 to 326.7 mL; p = 0.6787), RKV (Mean difference: - 58.5 ± 507.7 mL; 95%CI - 312.2 to 195.2 mL; p = 0.6466), and LKV (Mean difference: - 27.4 ± 413.5 mL; 95%CI - 234.1 to 179.2 mL; p = 0.7918) were lower with US-EL than with MRI-EL, although without significant differences. According to Passing and Bablok-regression analysis, the Spearman correlation-coefficient was 0.96 (95%CI 0.92 to 0.98); 0.91 (95%CI 0.82 to 0.96), and 0.94 (95%CI 0.87 to 0.97) in the RKV, LKV, and TKV, respectively; p < 0.0001 each, respectively. CCC of RKV, LKV, and TKV measurements were 0.95, 0.89, and 0.94, respectively. The mGFR and eGFR showed statistically significant negative correlations with TKV measured by both MRI-EL (p = 0.0281 and p = 0.0054, respectively) and US-EL (p = p = 0.0332 and p = 0.0040, respectively).</p><p><strong>Conclusions: </strong>This study found that ultrasound-based ellipsoid kidney volume measurements strongly correlated with MRI-based measurements, suggesting that ultrasound is a reliable, accessible alternative for assessing kidney volume, particularly when MRI is unavailable.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"17 1","pages":"13"},"PeriodicalIF":3.4,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11814422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}