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Splanchnic ultrasound to guide unloading in VA-ECMO. 内脏超声引导VA-ECMO卸载。
IF 2.9
Ultrasound Journal Pub Date : 2026-05-07 DOI: 10.5826/tuj.2026.18796
Guido Tavazzi, Stefano Avondo, Francesco Corradi
{"title":"Splanchnic ultrasound to guide unloading in VA-ECMO.","authors":"Guido Tavazzi, Stefano Avondo, Francesco Corradi","doi":"10.5826/tuj.2026.18796","DOIUrl":"https://doi.org/10.5826/tuj.2026.18796","url":null,"abstract":"<p><p>Patients supported with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may require left ventricular (LV) unloading to prevent pulmonary congestion and adverse hemodynamic interactions. However, defining the need and timing of unloading remains challenging, as current approaches rely predominantly on cardiac and pulmonary parameters, often neglecting systemic and organ-level congestion. We report the case of a 53-year-old woman admitted with cardiogenic shock following pericardial drainage and mediastinal mass biopsy. Due to rapid hemodynamic deterioration, VA-ECMO was initiated, resulting in stabilization. Early echocardiographic assessment showed severe biventricular dysfunction but evidence of partial aortic valve opening without LV distension. To further characterize the hemodynamic profile, splanchnic Doppler ultrasound was performed, demonstrating preserved renal arterial flow (resistive index <0.72), continuous intrarenal venous flow, and low portal vein pulsatility (<30%), consistent with a non-congestive phenotype. Based on this integrated assessment, LV unloading was deferred. Subsequent pulmonary artery catheterization confirmed low filling pressures despite reduced cardiac output. A diagnosis of stress-induced cardiomyopathy was suspected, and levosimendan was administered, leading to rapid improvement in cardiac function and successful ECMO weaning. Final pathology revealed a thymic neuroendocrine carcinoma. This case highlights the limitations of relying solely on cardiac indices to guide LV unloading decisions during VA-ECMO. Splanchnic Doppler provided a non-invasive, real-time evaluation of the perfusion-congestion balance at the organ level, complementing echocardiographic and invasive hemodynamic data. The integration of multimodal monitoring may allow a more comprehensive understanding of patient-device interaction and support individualized management strategies. Further research is needed to validate the role of splanchnic ultrasound in guiding unloading decisions and optimizing outcomes in patients with cardiogenic shock supported by VA-ECMO.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 1","pages":"18796"},"PeriodicalIF":2.9,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of post-extubation stridor using ultrasound measurement of subglottic airway diameter. 超声测量声门下气道直径预测拔管后喘鸣。
IF 2.9
Ultrasound Journal Pub Date : 2026-05-07 DOI: 10.5826/tuj.2026.18517
Nichanan Jongthitinon, Kantara Saelim, Supika Kritsanepaiboon, Kanokpan Ruangnapa, Pharsai Prasertsan, Wanaporn Anuntaseree
{"title":"Prediction of post-extubation stridor using ultrasound measurement of subglottic airway diameter.","authors":"Nichanan Jongthitinon, Kantara Saelim, Supika Kritsanepaiboon, Kanokpan Ruangnapa, Pharsai Prasertsan, Wanaporn Anuntaseree","doi":"10.5826/tuj.2026.18517","DOIUrl":"https://doi.org/10.5826/tuj.2026.18517","url":null,"abstract":"<p><strong>Background: </strong>Post-extubation stridor (PES) is a common complication in children in the pediatric intensive care unit (PICU). Despite the evaluation of various predictive tests, no single method has consistently demonstrated strong predictive value for PES. We evaluated the diagnostic utility of subglottic diameter ultrasonography for predicting PES within 48-h post-extubation in children.</p><p><strong>Material and methods: </strong>The prospective observational study in university-affiliated PICU was done in children aged 1 month to 15 years who successfully passed a spontaneous breathing trial (SBT) and were scheduled for extubation were enrolled between January 2024 and January 2025. During SBT and cuff deflation, subglottic ultrasonography was performed at a peak inspiratory pressure (PIP) of 15 cmH2O, and the subglottic ratio (SR) and intracricoid peritubular free space (IPFS) were calculated. Leak percentage was calculated as the ratio of the difference between inspiratory and expiratory volumes over inspiratory volume at each PIP level.</p><p><strong>Results: </strong>PES occurred in 33 of 176 (18.75%) patients. In children aged ≥1 year, SR was significantly associated with PES (adjusted OR, 3.78; 95% CI: 1.28-12.21). An SR <1.30 showed 70% sensitivity, 65% specificity, and 66% accuracy. IPFS <2.08 mm demonstrated 80% sensitivity, 65% specificity, and 68% accuracy. A leak percentage <36.77% at 25 cmH2O yielded 80% sensitivity, 47% specificity, and 53% accuracy. AUC values for SR, IPFS, and leak percentage were 0.664, 0.691, and 0.648, respectively.</p><p><strong>Conclusion: </strong>Among the evaluated parameters, IPFS showed the highest diagnostic performance for predicting PES, slightly outperforming the subglottic ratio in patients aged ≥1 year.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 1","pages":"18517"},"PeriodicalIF":2.9,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SPOT THE BOT: A comparative quality assessment of AI-generated written instructions for lung ultrasound training. SPOT THE BOT:对人工智能生成的肺部超声训练书面指令进行质量比较评估。
IF 2.9
Ultrasound Journal Pub Date : 2026-04-10 DOI: 10.5826/tuj.2026.18495
Adrian Wong, Nurul Liana Roslan, Serene Ho, Rou An Tan, Julina Noor, Gabriele Via, Francesco Corradi
{"title":"SPOT THE BOT: A comparative quality assessment of AI-generated written instructions for lung ultrasound training.","authors":"Adrian Wong, Nurul Liana Roslan, Serene Ho, Rou An Tan, Julina Noor, Gabriele Via, Francesco Corradi","doi":"10.5826/tuj.2026.18495","DOIUrl":"https://doi.org/10.5826/tuj.2026.18495","url":null,"abstract":"<p><strong>Background: </strong>The rapid proliferation of artificial intelligence (AI) in medical education has outpaced the development of quality assurance methods for AI-generated content. This study provides the first systematic evaluation of AI-generated instructional materials for lung ultrasound (LUS) training.</p><p><strong>Methods: </strong>The ATLAS study employed a cross-sectional, multi-rater evaluation design comparing six instruction sources (five AI systems and human-generated content) across ten LUS content sessions. Expert evaluators (n=39) assessed materials using five standardized domains: Medical Accuracy, Evidence Completeness, Clarity, Practical Utility, and Pedagogical Quality. Statistical analysis included Kruskal-Wallis tests and pairwise comparisons with Bonferroni correction.</p><p><strong>Results: </strong>Significant differences existed between instruction sources (H = 92.582, p < 0.001). Manus AI achieved the highest overall rating (4.55±0.83) and significantly outperformed human instructions in Medical Accuracy (p = 0.0002) and Evidence Completeness (p < 0.001). Gemini AI (3.94±0.97) performed statistically equivalent to human instructions (4.23±1.00). ChatGPT (2.62±1.35) and Meta (1.53±1.02) performed significantly worse than human instructions (p < 0.001). Clarity emerged as the most discriminating criterion with the widest performance range (1.53-4.54).</p><p><strong>Conclusions: </strong>Certain AI systems can generate high-quality LUS instructional materials that match or exceed human-generated content. However, significant quality variations across AI systems emphasize the critical importance of systematic evaluation before implementation. These findings support cautious but optimistic integration of high-performing AI systems into medical education with appropriate quality assurance measures.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 S1","pages":"18495"},"PeriodicalIF":2.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality evaluation of ultrasound images for fetal crown-rump length measurement at 11 to 14 weeks' gestation: A fusion model can be interpreted using SHAP method. 妊娠11 ~ 14周胎儿冠臀长测量超声图像质量评价:融合模型可以用SHAP方法解释。
IF 2.9
Ultrasound Journal Pub Date : 2026-04-09 DOI: 10.5826/tuj.2026.18334
Lu Liu, Ting Wang, Yanping Li, Hongyan Tian, Haidong Zhang, Chenyang Zhou, Wenjing Zhu, Wenjun Cai
{"title":"Quality evaluation of ultrasound images for fetal crown-rump length measurement at 11 to 14 weeks' gestation: A fusion model can be interpreted using SHAP method.","authors":"Lu Liu, Ting Wang, Yanping Li, Hongyan Tian, Haidong Zhang, Chenyang Zhou, Wenjing Zhu, Wenjun Cai","doi":"10.5826/tuj.2026.18334","DOIUrl":"https://doi.org/10.5826/tuj.2026.18334","url":null,"abstract":"<p><strong>Objectives: </strong>To explore a fusion model designed for the quality evaluation of ultrasound images utilized in fetal crown-rump length (CRL) measurement, and to use SHapley Additive exPlanations (SHAP) method to elucidate the model's decision-making processes.</p><p><strong>Methods: </strong>We retrospectively collected 1149 images of midsagittal planes of the entire fetus during early pregnancy from two hospitals. Two senior radiologists categorized the images into standard and non-standard planes. Seven image segmentation models were trained to select the best model for automatically segmenting the region of interest. The radiomics features and deep transfer learning (DTL) features were extracted and selected to establish radiomics models and DTL models. We also constructed fusion models to enhance the classification performance and the optimal one underwent comparison with radiologists. The SHAP method was employed to interpret and visualize the model.</p><p><strong>Results: </strong>The DeepLabV3 ResNet101 segmentation model demonstrated the highest performance (DSC: 97.15%). The early fusion model exhibited superior classification performance in validation set (AUC: 0.947, 95% CI: 0.924-0.970, accuracy: 88.4%, sensitivity: 83.0%, specificity: 92.7%, PPV: 90.1%, NPV: 87.3%, precision: 90.1%). The model demonstrated performance commensurate with that of senior radiologists while surpassing junior radiologists. Notably, when leveraging the model's support, there was a substantial improvement in their overall performance.</p><p><strong>Conclusions: </strong>The early fusion model demonstrated satisfactory performance in the intelligent quality evaluation of ultrasound images for CRL measurement. It has the potential to enhance the professional skills of junior radiologists.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 S1","pages":"18334"},"PeriodicalIF":2.9,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Towards reduced ultrasound localization microscopy acquisition times by uncoupling a bi-disperse microbubble population. 通过解耦双分散微泡种群来减少超声定位显微镜采集时间。
IF 2.9
Ultrasound Journal Pub Date : 2026-04-01 DOI: 10.5826/tuj.2026.18060
Giulia Tuccio, Lisa Te Winkel, Corinne Bruggeman, Wim Van Hoeve, Libertario Demi
{"title":"Towards reduced ultrasound localization microscopy acquisition times by uncoupling a bi-disperse microbubble population.","authors":"Giulia Tuccio, Lisa Te Winkel, Corinne Bruggeman, Wim Van Hoeve, Libertario Demi","doi":"10.5826/tuj.2026.18060","DOIUrl":"10.5826/tuj.2026.18060","url":null,"abstract":"<p><strong>Background: </strong>Ultrasound Localization Microscopy (ULM) is a milestone in the medical vascular imaging context, enabling the precise characterization of micro-vascular structures using ultrasound imaging. By accurately localizing contrast microbubbles (MBs) flowing in the circulatory system, ULM generates micro-resolved vascular images, overcoming the ultrasonic diffraction limit. However, as ULM relies on precise localization and tracking of individual MBs, high MB concentrations yield to increased localization errors and, ultimately, ULM failure. This constraint limits ULM to low MB concentrations, resulting in long acquisition times that pose challenges in clinical settings.    Methods: Here, we show the feasibility of uncoupling a bi-disperse MB population, composed of two monodisperse MB populations. The uncoupling is performed through a signal processing pipeline that exploits the strong nonlinear response of MBs having resonance frequency tuned with the transmission frequency. After uncoupling, ULM density and velocity flow maps are generated.   Results: Density and velocity maps are generated after uncoupling, when injecting the bi-disperse population individually and simultaneously in a vascular 3D-printed phantom. Furthermore, density maps generated after uncoupling are compared with the one obtained using standard ULM. Results demonstrate the capability of the proposed uncoupling pipeline to separate the bi-disperse population.     Conclusion: This work presents a signal processing pipeline to uncouple a bi-disperse MB population, formed by two monodisperse MB populations. Results are validated in a 3D-printed phantom and demonstrate the feasibility of the uncoupling which, in turn, would enable higher concentrations and reduce acquisition times for micro-vascular imaging.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 S1","pages":"18060"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147595239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic right diaphragmatic herniation revealed by point-of-care ultrasound in hepatic hydrothorax. 肝性胸水患者动态右膈疝。
IF 2.9
Ultrasound Journal Pub Date : 2026-04-01 DOI: 10.5826/tuj.2026.18198
João Augusto Kops Simon, Gabriel Beilfuss Rieth, Tiago Severo Garcia, Diego Corsetti Mondadori, Augusto Wasielesky, José Augusto Santos Pellegrini
{"title":"Dynamic right diaphragmatic herniation revealed by point-of-care ultrasound in hepatic hydrothorax.","authors":"João Augusto Kops Simon, Gabriel Beilfuss Rieth, Tiago Severo Garcia, Diego Corsetti Mondadori, Augusto Wasielesky, José Augusto Santos Pellegrini","doi":"10.5826/tuj.2026.18198","DOIUrl":"https://doi.org/10.5826/tuj.2026.18198","url":null,"abstract":"","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 1","pages":"18198"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147595174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of paediatric point-of-care ultrasound in Spain: Present status and future perspectives. 儿科点护理超声在西班牙的作用:现状和未来的观点。
IF 2.9
Ultrasound Journal Pub Date : 2026-04-01 DOI: 10.5826/tuj.2026.18403
Luis Ortiz-González, Luis Ortiz-Peces, Carlos Ortiz-Peces
{"title":"The role of paediatric point-of-care ultrasound in Spain: Present status and future perspectives.","authors":"Luis Ortiz-González, Luis Ortiz-Peces, Carlos Ortiz-Peces","doi":"10.5826/tuj.2026.18403","DOIUrl":"https://doi.org/10.5826/tuj.2026.18403","url":null,"abstract":"<p><strong>Introduction: </strong>The use of ultrasound by physicians not specialized in diagnostic radiology, as an adjunct to physical examination, has been termed \"point-of-care ultrasound\". In the last decade, this technique has been implemented in various medical fields, particularly family medicine and in emergency and urgent care.</p><p><strong>Methodology: </strong>A descriptive, cross-sectional observational study was conducted, involving a survey of physicians (mostly pediatricians) who had attended a training course in pediatric point-of-care ultrasound organized by different scientific societies. The aim was to obtain feedback from the pediatricians on the use, usefulness, barriers and training in ultrasound.</p><p><strong>Results: </strong>A total of 126 physicians were interviewed, most of whom declared having access to ultrasound. However, less than half of them made use of such devices, due to considerable difficulties, including lack of time and training. A total of 96.8% of those surveyed considered that ultrasound should be part of the training protocol of physicians specializing in pediatrics. The vast majority believed ultrasound training to be very important but considered their level of experience with the technique to be basic.</p><p><strong>Discussion: </strong>The implementation of point-of-care ultrasound in pediatrics is still limited in Spain, though the professionals agree on highlighting its relevance in daily practice. Among the most prominent benefits are resource optimization and shortening of the time to diagnosis. The participants agree that competence in the technique should be incorporated in a structured manner to the training of physicians specializing in pediatrics.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 1","pages":"18403"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147595242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Description of an independently developed quality assessment tool to meet emergency department credentialing and Emergency Ultrasound Fellowship Accreditation Council guidelines. 描述独立开发的质量评估工具,以满足急诊科资格认证和急诊超声研究员资格认证委员会的指导方针。
IF 2.9
Ultrasound Journal Pub Date : 2026-04-01 DOI: 10.5826/tuj.2026.18025
Michael Vu, Richard Gordon, Sara Miller, Katheryn Larimore, Carrie Bakunas, Victoria Morris, Ryan Walsh, Benjamin Karfunkle
{"title":"Description of an independently developed quality assessment tool to meet emergency department credentialing and Emergency Ultrasound Fellowship Accreditation Council guidelines.","authors":"Michael Vu, Richard Gordon, Sara Miller, Katheryn Larimore, Carrie Bakunas, Victoria Morris, Ryan Walsh, Benjamin Karfunkle","doi":"10.5826/tuj.2026.18025","DOIUrl":"https://doi.org/10.5826/tuj.2026.18025","url":null,"abstract":"<p><strong>Background: </strong>Quality assurance (QA) review is essential to any point-of-care ultrasound (POCUS) program that credentials emergency clinicians or hosts an Emergency Ultrasound Fellowship Accreditation Council (EUFAC) accredited fellowship. Commercially designed QA solutions exist but may not be accessible to all programs due to budgetary or institution-specific administration constraints.</p><p><strong>Objectives: </strong>The authors aimed to develop a robust, standalone, HIPAA-compliant POCUS QA database which satisfies both credentialing requirements and EUFAC review goals.</p><p><strong>Methods: </strong>An indexed, searchable electronic QA database was developed using Google workspace. The database was inspected reviewer disagreement trends that led to feedback at the individual and departmental level and was used to satisfy QA review requirements for ultrasound fellows.</p><p><strong>Results: </strong>Since deployment of the database in July 2021, 2742 studies have undergone QA review out of approximately 15,000 studies performed (18.3%). Reviewers disagreed with some portion of the interpretation in 848 (24.8%) exams, most commonly abdominal aortic aneurysm evaluation (n = 45 exams, 31.1%) and basic echocardiography (n = 1203 exams, 27.9%). Disagreement was least common for male genitourinary exams (n = 19 exams, 0%) and advanced echocardiograms (n=57, 15.8%), likely reflecting operator experience. For 209 (7.6%) studies, feedback to the clinicians was warranted and delivered via direct communication. This process has resulted in department-level education in consistently deficient areas.</p><p><strong>Conclusion: </strong>We present our lightweight, easily reproducible alternative to commercial POCUS QA solutions that has led to targeted feedback and department-level education while also satisfying accreditation requirements.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 1","pages":"18025"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147595153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Accuracy of Sonographic Signs of Extrapulmonary Tuberculosis and Treatment Response Monitoring in HIV-Positive and -Negative Populations. hiv阳性和阴性人群肺外结核超声征象诊断准确性及治疗反应监测。
IF 2.9
Ultrasound Journal Pub Date : 2026-03-17 DOI: 10.5826/tuj.2026.18222
Robert Ndege, Farida Bani, Omary Ngome, Mohamed Sasamalo, Dorcas Mnzava, Fiona Vanobberghen, Daniel Paris, Maja Weisser, Martin Rohacek
{"title":"Diagnostic Accuracy of Sonographic Signs of Extrapulmonary Tuberculosis and Treatment Response Monitoring in HIV-Positive and -Negative Populations.","authors":"Robert Ndege, Farida Bani, Omary Ngome, Mohamed Sasamalo, Dorcas Mnzava, Fiona Vanobberghen, Daniel Paris, Maja Weisser, Martin Rohacek","doi":"10.5826/tuj.2026.18222","DOIUrl":"https://doi.org/10.5826/tuj.2026.18222","url":null,"abstract":"<p><p>Background Diagnosis and monitoring of extrapulmonary tuberculosis (EPTB) remains challenging. Ultrasound such as the extended focused assessment for HIV-associated tuberculosis (eFASH) protocol might improve diagnosis and monitoring of treatment responses. This study determined the diagnostic accuracy of eFASH for EPTB and its value in monitoring EPTB treatment response compared with clinical signs and symptoms. Methods We performed a post-hoc analysis of a trial assessing eFASH impact on management of adults with suspected EPTB. Participants who had baseline and follow-up ultrasound examinations were included. We assessed the diagnostic accuracy of eFASH and compared the evolution of eFASH and clinical signs and symptoms in participants with definite EPTB, stratified by favorable treatment outcomes at 6 months. Results In 296 included participants (95 with definite EPTB, 201 with no definite EPTB),  the most common eFASH signs were pleural effusion (47%) and pulmonary B-lines with subpleural granular artefacts (34%). Pleural effusion was the only sign that persisted beyond 6 months. eFASH had a sensitivity of 93.7% (95% CI, 86.8-97.6) and a specificity of 37.8% (95% CI, 31.1- 44.9) for definite EPTB. At 2 months, favorable outcomes were similar between participants with full and partial resolution of eFASH signs (83% versus 81%). In contrast, a higher proportion of favorable outcomes was seen in participants with full resolution of clinical signs and symptoms (90% versus 60%). Conclusion eFASH shows high sensitivity but low specificity for definite EPTB. Ultrasound can be used alongside clinical signs and symptoms to monitor treatment response in patients with EPTB.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 1","pages":"18222"},"PeriodicalIF":2.9,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147475808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of measuring left ventricular outflow tract velocity time integral as a predictor for stroke volume in pregnant women in labor. 测量左心室流出道速度时间积分作为临产孕妇脑卒中量预测指标的可行性。
IF 2.9
Ultrasound Journal Pub Date : 2026-03-10 DOI: 10.5826/tuj.2026.18246
Mohamed Eissa, George Dumitrascu, Elizabeth Miller, Jennifer Racine, Victoria Postnikova, Wesley Rajaleelan, Wesley Edwards, Hesham Talab, Daniel McIsaac
{"title":"Feasibility of measuring left ventricular outflow tract velocity time integral as a predictor for stroke volume in pregnant women in labor.","authors":"Mohamed Eissa, George Dumitrascu, Elizabeth Miller, Jennifer Racine, Victoria Postnikova, Wesley Rajaleelan, Wesley Edwards, Hesham Talab, Daniel McIsaac","doi":"10.5826/tuj.2026.18246","DOIUrl":"https://doi.org/10.5826/tuj.2026.18246","url":null,"abstract":"<p><strong>Background: </strong>Pregnancy is a time of significant hemodynamic changes. Maintaining adequate cardiac output (CO) and uteroplacental perfusion is a priority in parturients, for favorable maternal-fetal outcomes. Blood pressure is commonly used as a surrogate for CO, although it may poorly correlate with stroke volume (SV) and CO in some cases. An alternative approach is SV estimation using transthoracic echocardiography (TTE) based on the velocity-time integral (VTI) of the left ventricular outflow tract (LVOT). Although VTI has been validated as a tool to estimate SV and CO in acute care contexts, its feasibility and utility in obstetric anesthesia remain unexplored. Therefore, the objective of this study is to evaluate the feasibility and reproducibility of LVOT VTI measurements in parturients during labor.</p><p><strong>Methods: </strong>Following research ethics board approval, 55 full term pregnant female patients with a singleton pregnancy were recruited. TTE was used to calculate the LVOT VTI for each patient by the same anesthesiologist twice. Feasibility of obtaining the LVOT VTI was evaluated using time for image acquisition and the 3-Point Likert Scale for Imaging Quality. Intraclass correlation coefficients (ICC) were used to estimate intra-rater reliability.</p><p><strong>Results: </strong>LVOT VTI was obtained for all participants on both attempts. Mean time needed to obtain measurements was 63.7 seconds (95%CI 56.5 to 70.8) on the 1st attempt and 44.2 seconds (95%CI 38.7 to 49.8) on the 2nd attempt. Eighty-one (73.6%) images were rated as optimal, 29 (26.3%) were rated as suboptimal. Intra-rater reliability was excellent (ICC was 0.94 (95%CI 0.92 to 0.95).</p><p><strong>Conclusion: </strong>In singleton parturients, LVOT VTI measurements can be routinely obtained in a timely fashion with excellent intra-rater reliability during labor. These results support the feasibility of LVOT VTI to estimate and trend SV.</p>","PeriodicalId":36911,"journal":{"name":"Ultrasound Journal","volume":"18 1","pages":"18246"},"PeriodicalIF":2.9,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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