Yari Nebel, Kurt Williams, Leslie A Lyons, Carol Reinero, Riccardo Ferriani, Roberto Toschi Corneliani, Ilaria Spalla
{"title":"Developmental lung disease in a cat associated with high probability of severe pulmonary hypertension: natural history, histopathology and genetic analysis.","authors":"Yari Nebel, Kurt Williams, Leslie A Lyons, Carol Reinero, Riccardo Ferriani, Roberto Toschi Corneliani, Ilaria Spalla","doi":"10.1177/20551169241249003","DOIUrl":"10.1177/20551169241249003","url":null,"abstract":"<p><strong>Case summary: </strong>This report describes the diagnostic findings, natural history and genetic analysis of the candidate gene <i>Forkhead Box F1</i> (<i>FOXF1</i>) in a young cat with developmental lung disease and high probability of pulmonary hypertension. A 1-year-old male entire Chartreux cat was referred for cardiac murmur investigation and exercise intolerance. Echocardiography identified a high-velocity tricuspid regurgitant jet with right-sided cardiac changes, supporting a high probability of pulmonary hypertension. No congenital cardiac shunts or left-sided cardiac changes were found to support a primary cardiac cause of pulmonary hypertension. Extensive laboratory work, thoracic radiographs and CT were performed. Histopathological characterisation (lung biopsy and later post mortem) was necessary to reach the final diagnosis. Eight months after diagnosis, the cat developed right-sided congestive heart failure, eventually leading to euthanasia. Survival from diagnosis to death was 12 months.</p><p><strong>Relevance and novel information: </strong>Developmental lung disease belongs to a group of diffuse lung diseases in humans associated with pulmonary hypertension. The veterinary literature describing lung growth disorders in cats is sparse, and the present report provides information on clinical presentation and progression alongside a thorough diagnostic workup, which may aid clinicians in identifying this condition. Lung biopsy was pivotal in reaching the final diagnosis. No causal variants in <i>FOXF1</i> were identified.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241249003"},"PeriodicalIF":0.7,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11141230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful medical management of a vaginal wall tear in feline dystocia.","authors":"Shaylan Meyer, Alexia Berg","doi":"10.1177/20551169241243016","DOIUrl":"10.1177/20551169241243016","url":null,"abstract":"<p><strong>Case summary: </strong>A 2-year-old domestic shorthair queen sustained a tear in the vaginal wall through which the queen herniated a fetus during parturition. An exploratory laparotomy was performed, the patient had an ovariohysterectomy and the fetus was removed vaginally. The tear was managed medically with antibiotics, analgesics and careful monitoring. Assessment of the injury site 2 weeks later confirmed successful healing without the need for surgical intervention in the vaginal wall.</p><p><strong>Relevance and novel information: </strong>This is the first report in veterinary medicine describing the successful medical management of a dystocia-related vaginal wall tear in a feline patient without surgical repair.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241243016"},"PeriodicalIF":0.7,"publicationDate":"2024-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atropine sulfate as a continuous intravenous infusion for the treatment of organophosphate toxicity in a cat.","authors":"Edward Baker, Carl Southern, Jennifer Martinez","doi":"10.1177/20551169241249637","DOIUrl":"10.1177/20551169241249637","url":null,"abstract":"<p><strong>Case summary: </strong>A 1-year-old male neutered domestic shorthair cat presented on an emergency basis with clinical signs suspected to be secondary to organophosphate (OP) toxicity. The control of clinical abnormalities (bradycardia, obtundation, tachypnea, anorexia) was achieved using high-dose continuous rate intravenous infusion (CRI) of atropine sulfate (maximum rate 0.1 mg/kg/h). After 5 days of hospitalization, the patient made a full clinical recovery without the development of atropine toxicity, intermediate syndrome or delayed polyneuropathy at 4 weeks after discharge.</p><p><strong>Relevance and novel information: </strong>Treatment of OP toxicity in cats is sparsely reported in veterinary literature. Current standards of treatment and published protocols recommend the use of atropine sulfate as intermittent boluses for the treatment of muscarinic signs of toxicity; however, there is a paucity of information regarding the safety and efficacy of atropine sulfate as a CRI for severe toxicosis as described in humans. This report includes the first published case using such a treatment protocol in a cat.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241249637"},"PeriodicalIF":0.7,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11119382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combination of TPLO, medial and lateral augmentation techniques for the treatment of traumatic stifle luxation in a cat.","authors":"Paula Bartolomé I Gadea, Mario Coppola","doi":"10.1177/20551169241247439","DOIUrl":"10.1177/20551169241247439","url":null,"abstract":"<p><strong>Case summary: </strong>An 11-year-old female neutered domestic shorthair cat was referred for surgical management of a traumatic right stifle luxation. Orthopaedic examination of the affected stifle under general anaesthesia revealed joint effusion and craniocaudal and rotational instability. Cranial displacement of the tibia with respect to the femur and infrapatellar pad sign were identified on radiography. Intraoperatively, complete rupture of both cruciate ligaments and marked disruption of the mid and caudal poles of the medial and lateral menisci were observed. Both collateral ligaments appeared intact. The remnants of the injured cruciate ligaments were removed, and medial and lateral caudal hemimeniscectomies were performed. A tibial plateau levelling osteotomy (TPLO) was performed to address the craniocaudal stifle instability. Intraoperative assessment of the stifle revealed persistent instability with cranial tibial translation, internal and external rotation, and a positive caudal draw test. A lateral augmentation suture was employed to address the persistent cranial tibial translation and internal rotation. To successfully neutralise caudocranial and external rotational instability secondary to the caudal cruciate ligament deficiency, a medial augmentation suture was placed with the aid of three interference screws. Stifle stability was achieved. A modified Robert-Jones bandage was kept on for 24 h postoperatively. An excellent outcome was achieved, with successful limb function restoration.</p><p><strong>Relevance and novel information: </strong>This case report represents the first documented instance of feline traumatic stifle luxation repair by combining a corrective tibial osteotomy and extra-articular augmentation. Notably, it introduces the novel technique of implementing a TPLO with medial and lateral augmentation sutures to address multidirectional stifle instability.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241247439"},"PeriodicalIF":0.7,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11113046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141088185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Choledochoduodenostomy combined with Billroth II procedure for extrahepatic biliary obstruction and duodenal perforation in a cat.","authors":"Shintaro Tomura, Taisuke Iwata, Taichi Sugimoto, Ko Nakashima, Kazuhiro Kojima, Kazuyuki Uchida, Atsushi Fujita","doi":"10.1177/20551169241246415","DOIUrl":"10.1177/20551169241246415","url":null,"abstract":"<p><strong>Case summary: </strong>A 5-year-old neutered Somali cat presented with a 2-week history of icterus. Diagnostic imaging revealed extrahepatic biliary obstruction (EHBO) due to a common bile duct (CBD) mass. During exploratory laparotomy, a duodenal perforation was discovered incidentally. Choledochoduodenostomy combined with the Billroth II procedure was performed after resection of the CBD mass and the proximal duodenum to treat the EHBO and duodenal perforation. Based on histological and immunohistochemical findings, the CBD mass was diagnosed as a neuroendocrine carcinoma with gastrin-producing cell differentiation. The cat recovered almost uneventfully and was discharged 11 days after surgery. The cat survived for nearly 100 days without recurrence of EHBO or duodenal perforation; however, intermittent vomiting and weight loss persisted despite supportive medications.</p><p><strong>Relevance and novel information: </strong>To the best of our knowledge, there is no detailed report on the application of choledochoduodenostomy combined with the Billroth II procedure in cats, as we used to treat the EHBO and duodenal perforation in the present case. As serum gastrin concentrations were elevated on the first day of hospitalisation, the CBD mass was diagnosed as a neuroendocrine carcinoma with gastrin-producing cell differentiation, which seemed to have caused not only EHBO but also duodenal perforation (Zollinger-Ellison syndrome). The cat survived for almost 100 days without any perioperative complications. However, this combined procedure might be considered as only a salvage option and not as a definitive treatment option in cats requiring simultaneous biliary and gastrointestinal reconstruction because postoperative supportive care could not improve the cat's condition or maintain its quality of life.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241246415"},"PeriodicalIF":0.7,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11100399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful treatment of non-pruritus, excessive hair shedding and scales in a cat due to <i>Demodex gatoi</i> with fluralaner topical spot-on.","authors":"Thapanee Chuenngam, Suttiwee Chermprapai","doi":"10.1177/20551169241246866","DOIUrl":"10.1177/20551169241246866","url":null,"abstract":"<p><strong>Case summary: </strong>A 1-year-old female intact Scottish Fold cat was presented with a 1-month history of excessive hair shedding with white scales on the coat without pruritus. The cat lived mostly indoors and had no history of any systemic disease. Dermatological examinations were performed step by step. Several <i>Demodex gatoi</i> were identified from cellophane tape impressions from the scales and examined under a low-power objective (10×) microscope. Skin cytology showed keratinocytes without any microorganisms. Based on the findings, fluralaner (Bravecto for cats; MSD) spot-on was used once every 12 weeks for ectoparasiticidal control. An essential fatty acid supplement was recommended to repair and restore the coat and skin barrier. After 4 weeks of treatment, the cat showed substantial improvement, with a normal coat and no scales. Re-examination using a cellophane tape impression for mites was negative. Ectoparasitic control is highly recommended regularly for the treatment and prevention of ectoparasites.</p><p><strong>Relevance and novel information: </strong>Feline demodicosis is an uncommon parasitic dermatosis with primary clinical signs that may cause generalised or localised dermatitis with frequent pruritus, erythema and alopecia. The aims of this study were to report on dermatological lesions with excessive hair shedding and scales in a cat that were caused by demodicosis, without presenting the main clinical sign of pruritus or overgrooming. In addition, to the authors' knowledge, this is the first report of the successful treatment of demodicosis due to <i>D gatoi</i> infestation with fluralaner single spot-on in an off-label use that was safe and easy to apply clinically.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241246866"},"PeriodicalIF":0.7,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140946265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Léa Bouccara, Antoine Dunie-Merigot, Laure Poujol, Laurent Blond, Franck Jolivet
{"title":"Long-lasting hypoaldosteronism after adrenalectomy in a cat with hyperaldosteronism.","authors":"Léa Bouccara, Antoine Dunie-Merigot, Laure Poujol, Laurent Blond, Franck Jolivet","doi":"10.1177/20551169241243012","DOIUrl":"10.1177/20551169241243012","url":null,"abstract":"<p><strong>Case summary: </strong>A 10-year-old neutered male domestic shorthair cat was presented with an abdominal mass, associated renal failure, chronic vomiting, anorexia and progressive polyuria/polydipsia lasting for 3 weeks. Clinical examination and initial blood work revealed azotaemia, hypokalaemia and hypertension. Abdominal ultrasound showed an adrenal mass with a diameter of 3 cm near the right kidney. High serum aldosterone suggested primary hyperaldosteronism. Surgery enabled identification of the mass and its excision along with the right adrenal gland. Histologically, carcinoma of the adrenal cortex was diagnosed. Postoperatively, an increase in serum creatinine and potassium, along with a low serum aldosterone, led to a diagnosis of hypoaldosteronism. Mineralocorticoid therapy for 6 months was necessary, resulting in clinical and biological improvement.</p><p><strong>Relevance and novel information: </strong>To our knowledge, this case describes the longest-lasting reported secondary hypoaldosteronism in a cat, after unilateral adrenalectomy for an adrenal carcinoma with hyperaldosteronism.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241243012"},"PeriodicalIF":0.7,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11092530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandros Bourbos, Francesco Piana, Sorrel Judith Langley-Hobbs
{"title":"Total hip replacement in a cat with contralateral pelvic limb amputation.","authors":"Alexandros Bourbos, Francesco Piana, Sorrel Judith Langley-Hobbs","doi":"10.1177/20551169241232297","DOIUrl":"https://doi.org/10.1177/20551169241232297","url":null,"abstract":"<p><strong>Case summary: </strong>A 10-year-old male neutered domestic shorthair cat, which had previously had its contralateral pelvic limb amputated, was treated for coxofemoral degenerative joint disease (DJD) with a total hip replacement. The long-term outcome was favourable and no complications were recorded. Interestingly, the contralateral coxofemoral joint left at the time of the previous amputation developed DJD and became a source of pain for the cat and was subsequently excised.</p><p><strong>Relevance and novel information: </strong>This case report shows that total hip replacement is a viable option in cats with coxofemoral DJD and a contralateral limb amputation. Retained joints in amputated limbs may develop osteoarthritis and be a source of pain for a cat.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169241232297"},"PeriodicalIF":0.7,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of <i>Toxoplasma gondii</i> IgM and IgG positive cats in Los Angeles County, California.","authors":"Roubina Honarchian, Tracy Yen, Eva Ganz, Gie Kang","doi":"10.1177/20551169231222107","DOIUrl":"10.1177/20551169231222107","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to determine the prevalence of <i>Toxoplasma gondii</i> IgM and IgG positive cats in Los Angeles County, California. <i>T gondii</i> antibodies are common in sera from cats in most reported studies around the world. Although the majority of infected cats never develop clinical disease, development of acute infection and recrudescence of latent infection secondary to immunosuppression has been reported. Knowledge of the serologic status of <i>T gondii</i> may be important when considering immunosuppressive treatments.</p><p><strong>Methods: </strong><i>T gondii</i> IgM and IgG antibody titers were measured in 225 cats. Sera from owned cats tested at a multispecialty veterinary hospital were included both retrospectively and prospectively (n = 125). Sera from feral cats tested through a collaborating humane society were included prospectively (n = 100).</p><p><strong>Results: </strong>Of the 13 (5.8%) cats with IgM titers, 10 were positive at the minimal cut-off titer (1:64), one cat was clinically ill and none were currently positive for IgG antibodies, suggesting false-positive results for nine cats, giving an adjusted IgM prevalence rate of 1.8% (95% CI 0.7-4.5). A total of five (2.2%) cats were positive for IgG antibodies and no cat was positive for both antibodies.</p><p><strong>Conclusions and relevance: </strong>Most studies of <i>T gondii</i> antibodies in cat sera from California have shown higher prevalence rates, suggesting the cats in this municipality have a low risk of exposure. The study emphasizes that serological test results do not necessarily correlate to the presence of clinical illness.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169231222107"},"PeriodicalIF":0.7,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139991377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Positioning head tilt observed in two cats with myasthenia gravis.","authors":"Shinji Tamura, Yuya Nakamoto, Yasuhiro Sozu, Yumiko Tamura","doi":"10.1177/20551169231224534","DOIUrl":"10.1177/20551169231224534","url":null,"abstract":"<p><strong>Case series summary: </strong>A 1-year-old castrated male domestic shorthair cat was suspected with myasthenia gravis (MG) based on neurological examination, complete blood count (CBC), serum biochemistry, radiography and electrophysiological examination. In addition, a 9-year-old spayed female domestic shorthair cat was diagnosed with MG based on neurological examination, CBC, serum biochemistry, radiography, ultrasonography and increased acetylcholine receptor antibody titre. Positioning head tilt (PHT) was observed at the time of diagnosis in both cats.</p><p><strong>Relevance and novel information: </strong>Although the pathophysiology of PHT in cats is not fully understood, the mechanism for PHT in cats with MG may be similar to that of cats with hypokalaemic myopathy, supporting our hypothesis that muscle spindle dysfunction causes PHT.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169231224534"},"PeriodicalIF":0.7,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10865950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}