{"title":"在两只患有重症肌无力的猫身上观察到的头部定位倾斜。","authors":"Shinji Tamura, Yuya Nakamoto, Yasuhiro Sozu, Yumiko Tamura","doi":"10.1177/20551169231224534","DOIUrl":null,"url":null,"abstract":"<p><strong>Case series summary: </strong>A 1-year-old castrated male domestic shorthair cat was suspected with myasthenia gravis (MG) based on neurological examination, complete blood count (CBC), serum biochemistry, radiography and electrophysiological examination. In addition, a 9-year-old spayed female domestic shorthair cat was diagnosed with MG based on neurological examination, CBC, serum biochemistry, radiography, ultrasonography and increased acetylcholine receptor antibody titre. Positioning head tilt (PHT) was observed at the time of diagnosis in both cats.</p><p><strong>Relevance and novel information: </strong>Although the pathophysiology of PHT in cats is not fully understood, the mechanism for PHT in cats with MG may be similar to that of cats with hypokalaemic myopathy, supporting our hypothesis that muscle spindle dysfunction causes PHT.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"10 1","pages":"20551169231224534"},"PeriodicalIF":0.7000,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10865950/pdf/","citationCount":"0","resultStr":"{\"title\":\"Positioning head tilt observed in two cats with myasthenia gravis.\",\"authors\":\"Shinji Tamura, Yuya Nakamoto, Yasuhiro Sozu, Yumiko Tamura\",\"doi\":\"10.1177/20551169231224534\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Case series summary: </strong>A 1-year-old castrated male domestic shorthair cat was suspected with myasthenia gravis (MG) based on neurological examination, complete blood count (CBC), serum biochemistry, radiography and electrophysiological examination. In addition, a 9-year-old spayed female domestic shorthair cat was diagnosed with MG based on neurological examination, CBC, serum biochemistry, radiography, ultrasonography and increased acetylcholine receptor antibody titre. Positioning head tilt (PHT) was observed at the time of diagnosis in both cats.</p><p><strong>Relevance and novel information: </strong>Although the pathophysiology of PHT in cats is not fully understood, the mechanism for PHT in cats with MG may be similar to that of cats with hypokalaemic myopathy, supporting our hypothesis that muscle spindle dysfunction causes PHT.</p>\",\"PeriodicalId\":36588,\"journal\":{\"name\":\"Journal of Feline Medicine and Surgery Open Reports\",\"volume\":\"10 1\",\"pages\":\"20551169231224534\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10865950/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Feline Medicine and Surgery Open Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/20551169231224534\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Feline Medicine and Surgery Open Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/20551169231224534","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Positioning head tilt observed in two cats with myasthenia gravis.
Case series summary: A 1-year-old castrated male domestic shorthair cat was suspected with myasthenia gravis (MG) based on neurological examination, complete blood count (CBC), serum biochemistry, radiography and electrophysiological examination. In addition, a 9-year-old spayed female domestic shorthair cat was diagnosed with MG based on neurological examination, CBC, serum biochemistry, radiography, ultrasonography and increased acetylcholine receptor antibody titre. Positioning head tilt (PHT) was observed at the time of diagnosis in both cats.
Relevance and novel information: Although the pathophysiology of PHT in cats is not fully understood, the mechanism for PHT in cats with MG may be similar to that of cats with hypokalaemic myopathy, supporting our hypothesis that muscle spindle dysfunction causes PHT.
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