Vision (Switzerland)最新文献

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Ocular and General Proprioception in Dyslexic Children: A Review of Their Diurnal and Nocturnal Dysfunctions and Their Repercussions. 阅读困难儿童的眼本体感觉和全身本体感觉:对其昼夜功能障碍及其影响的回顾。
Vision (Switzerland) Pub Date : 2025-05-20 DOI: 10.3390/vision9020044
Patrick Quercia, Kalvin Chavet, Jérémie Gaveau
{"title":"Ocular and General Proprioception in Dyslexic Children: A Review of Their Diurnal and Nocturnal Dysfunctions and Their Repercussions.","authors":"Patrick Quercia, Kalvin Chavet, Jérémie Gaveau","doi":"10.3390/vision9020044","DOIUrl":"10.3390/vision9020044","url":null,"abstract":"<p><p>We provide a summary of the research conducted in our laboratory on the relationship between ocular proprioception, general proprioception, and dyslexia. Dyslexic children show a marked proprioceptive deficit which affects motor control, attention and spatial perception. The spatial disturbances are expressed by the presence of a vertical microheterophoria which has very specific characteristics. It is associated with abnormal tone of the oblique muscles and can be modified by means of very low powered prisms and/or remote sensory stimulation. When ocular proprioception is modified, sounds cause stochastic visual losses. This may interfere with the association between phonemes and graphemes, which is necessary for learning to read. The effects of a generalized nocturnal proprioceptive disorder may play a role in the abnormal brain development that has been observed in dyslexic children.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception and Decision-Making in Virtual Telepsychology Spaces and Professionals. 虚拟远程心理空间与专业人员的感知与决策。
Vision (Switzerland) Pub Date : 2025-05-06 DOI: 10.3390/vision9020043
Luis-Lucio Lobato Rincón, Maria Ángeles Medina Sánchez, Rubén Tovar Bordón
{"title":"Perception and Decision-Making in Virtual Telepsychology Spaces and Professionals.","authors":"Luis-Lucio Lobato Rincón, Maria Ángeles Medina Sánchez, Rubén Tovar Bordón","doi":"10.3390/vision9020043","DOIUrl":"10.3390/vision9020043","url":null,"abstract":"<p><p>Humans interact with virtual environments for a variety of purposes, and the use of telemedicine services and e-health platforms has become increasingly significant in recent years. Telepsychology is an emerging service and is understood as the provision of psychological aid and counseling through the use of telecommunication technologies. This study investigates the impact of visual backgrounds in a mental health simulation app and explores the decision-making of potential patients for telepsychology. In this experimental study, we developed an instrument to assess the preferences for manipulated features of photomontages and portraits. A total of 310 participants from diverse backgrounds were surveyed about their preferences regarding visual backgrounds and silhouettes for this hypothetical service, with key independent variables such as complexity, naturalness, and color hues being manipulated. Our findings represent the first example of data collected on background preferences in telepsychology. The results suggest a preference for backgrounds with medium complexity and naturalness for clinical settings. Additionally, we observed variations in preferences based on gender and age. These findings highlight the importance of customizing visual elements to enhance patient engagement in telepsychology.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Latin American Prevalence of Glaucoma: A Systematic Review and Meta-Analysis. 拉丁美洲青光眼患病率:系统回顾和荟萃分析。
Vision (Switzerland) Pub Date : 2025-05-05 DOI: 10.3390/vision9020042
Denisse J Mora-Paez, Jaime Guedes, Dillan Cunha Amaral, Marcelo Alves Ferreira, Bruno F Fernandes, Sacha F Pereira, Bruno Botton, Alisha Desai, Helena Messinger Pakter, Fabio Lavinsky, Adroaldo Alencar Costa Filho
{"title":"Latin American Prevalence of Glaucoma: A Systematic Review and Meta-Analysis.","authors":"Denisse J Mora-Paez, Jaime Guedes, Dillan Cunha Amaral, Marcelo Alves Ferreira, Bruno F Fernandes, Sacha F Pereira, Bruno Botton, Alisha Desai, Helena Messinger Pakter, Fabio Lavinsky, Adroaldo Alencar Costa Filho","doi":"10.3390/vision9020042","DOIUrl":"10.3390/vision9020042","url":null,"abstract":"<p><p>We conducted a systematic review and meta-analysis to estimate the prevalence of all types of glaucoma in Latin America (LATAM) and evaluate potential demographic associations. This study followed PRISMA guidelines and was registered in PROSPERO (CRD42024506330). A comprehensive search of PubMed, SciELO, and Web of Science was conducted to identify population-based or cross-sectional studies reporting glaucoma prevalence in LATAM. Studies were categorized into two groups: Group 1 included general population studies without selection based on visual acuity (VA), and Group 2 included studies limited to individuals with VA < 20/60. Data from five studies in Group 1 (25,288 individuals) and eight studies in Group 2 (29,882 individuals) were analyzed using R software. The pooled prevalence of glaucoma was 4% (95% CI: 1-3%) in Group 1 and 1% (95% CI: 0-1%) in Group 2. No statistically significant associations were found between glaucoma prevalence and sex (<i>p</i> = 0.08) or age (<i>p</i> = 0.5669). Although our findings highlight the relevance of glaucoma as a public health concern in LATAM, the limited number of available studies and methodological variability reduce the certainty of the estimates.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence of the Level of Monovision upon Early Outcomes Following the Bilateral Implantation of an Enhanced Monovision Intraocular Lens. 单视水平对双侧增强型单视人工晶状体植入术早期预后的影响。
Vision (Switzerland) Pub Date : 2025-05-03 DOI: 10.3390/vision9020041
Richard N McNeely, Stephen Stewart, Niraj Mandal, Salissou Moutari, Allon Barsam, Jonathan E Moore
{"title":"The Influence of the Level of Monovision upon Early Outcomes Following the Bilateral Implantation of an Enhanced Monovision Intraocular Lens.","authors":"Richard N McNeely, Stephen Stewart, Niraj Mandal, Salissou Moutari, Allon Barsam, Jonathan E Moore","doi":"10.3390/vision9020041","DOIUrl":"10.3390/vision9020041","url":null,"abstract":"<p><p>This article provides an assessment of the impact of different levels of monovision upon early visual outcomes and quality of vision (QoV) following the bilateral implantation of enhanced monovision intraocular lenses (IOLs). Consecutive patients implanted bilaterally with the Rayone EMV (Rayner) were recruited. The dominant eye was targeted for emmetropia, and myopia was targeted in the nondominant eye. Patients were categorized based upon the postoperative refractive outcome in the nondominant eye as follows: Group A: -0.50 to -1.0 D (<i>n</i> = 40), Group B: <-1.00 = D (<i>n</i> = 46). Uncorrected distance (UDVA), intermediate (UIVA), and near (UNVA) visual acuity, and QoV were compared 3 months postoperatively. Binocular UIVA was 0.05 ± 0.10 and -0.01 ± 0.11logMAR (<i>p</i> = 0.03) in the two respective groups, and binocular UNVA was 0.23 ± 0.09 and 0.14 ± 0.09logMAR (<i>p</i> < 0.001). Day QoV was 8.77 ± 1.33 and 8.13 ± 1.34 for night QoV in group A, and 8.85 ± 0.99 and 7.85 ± 1.35, respectively, in group B. Group A had a lower spectacle independence rate of 55% compared to 89.1%. This IOL provides a satisfactory range of vision with high QoV satisfaction. A postoperative refractive error of -1.0 D or more in the nondominant eye significantly improves binocular UIVA, UNVA, and spectacle independence, without negatively impacting QoV.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association Between Sensory Impairment and Adherence to COVID-19 Prevention Measures in the Adult California Health Interview Survey Population. 加州成人健康访谈调查人群中感觉障碍与COVID-19预防措施依从性之间的关系
Vision (Switzerland) Pub Date : 2025-05-02 DOI: 10.3390/vision9020040
Catherine T Cascavita, Ahmad Santina, Ken Kitayama, Fei Yu, Victoria L Tseng, Anne L Coleman
{"title":"The Association Between Sensory Impairment and Adherence to COVID-19 Prevention Measures in the Adult California Health Interview Survey Population.","authors":"Catherine T Cascavita, Ahmad Santina, Ken Kitayama, Fei Yu, Victoria L Tseng, Anne L Coleman","doi":"10.3390/vision9020040","DOIUrl":"10.3390/vision9020040","url":null,"abstract":"<p><p>This study explores the association between vision/hearing impairment and COVID-19 prevention strategies in the 2020 and 2021 California Health Interview Survey (CHIS). This cross-sectional study used data from the 2020 and 2021 CHIS. The exposure of interest was self-reported history of sensory impairment. The outcome of interest was adherence to COVID-19 mitigation strategies defined as obtaining a COVID-19 vaccine, face mask adherence, hand washing, social distancing, and not gathering with non-household members. Logistic regression models examined the association between sensory impairment and adherence to COVID-19 mitigation strategies, controlling for age, sex, race and ethnicity, general health status, and household income. All analyses were weighted according to the CHIS sampling design. With 24,453 California adults representing 29,649,837 people, the weighted prevalence of sensory impairment was 6.1% (1,808,640/29,649,837). The regression revealed that adults with sensory impairment were 80% more likely not to maintain social distancing (odds ratio: 1.80, 95%CI: 1.03-3.13, <i>p</i> = 0.04) compared to those without impairment. No significant differences were found for adherence to other COVID-19 strategies. Individuals with sensory impairment may have increased difficulty with physical distancing due to their underlying impairment. Further studies are needed to explore risk reduction strategies for COVID-19 and the transmission of other infections for those with sensory impairment.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Training Improves Avoidance of Natural Sick Faces: Changes in Visual Attention and Approach Decisions. 训练提高对自然病态面孔的回避:视觉注意力和接近决策的改变。
Vision (Switzerland) Pub Date : 2025-05-02 DOI: 10.3390/vision9020039
Tiffany S Leung, Krisztina V Jakobsen, Sarah E Maylott, Arushi Malik, Shuo Zhang, Elizabeth A Simpson
{"title":"Training Improves Avoidance of Natural Sick Faces: Changes in Visual Attention and Approach Decisions.","authors":"Tiffany S Leung, Krisztina V Jakobsen, Sarah E Maylott, Arushi Malik, Shuo Zhang, Elizabeth A Simpson","doi":"10.3390/vision9020039","DOIUrl":"10.3390/vision9020039","url":null,"abstract":"<p><p>Humans evolved a behavioral immune system to avoid infectious disease, including the ability to detect sickness in faces. However, it is unclear whether the ability to recognize and avoid facial cues of disease is malleable, flexibly calibrated by experience. Thus, we experimentally tested whether we can improve adults' (<i>N</i> = 133) lassitude (sick) face perception, measuring their recognition, avoidance, and visual attention to naturally sick and healthy faces. Participants randomly assigned to a training about disease, but not a control group, were better at avoiding sick people. The disease-trained group also looked more equally between sick and healthy faces when identifying who was sick compared to the control group who looked longer at the sick faces than the healthy faces. Though we detected no group differences in time looking at the eyes and at the mouths, the disease-trained group used these features more to decide who was sick, reflecting key features of the lassitude expression. Our findings suggest that facial sickness perception may be flexible, influenced by experience, and underscore the need for future studies to test how to further strengthen this skill. Ultimately, developing interventions that use this sick face plasticity may reduce disease transmission.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Phenomenology of Offline Perception: Multisensory Profiles of Voluntary Mental Imagery and Dream Imagery. 离线感知的现象学:自愿心理意象和梦意象的多感官概况。
Vision (Switzerland) Pub Date : 2025-04-21 DOI: 10.3390/vision9020037
Maren Bilzer, Merlin Monzel
{"title":"The Phenomenology of Offline Perception: Multisensory Profiles of Voluntary Mental Imagery and Dream Imagery.","authors":"Maren Bilzer, Merlin Monzel","doi":"10.3390/vision9020037","DOIUrl":"https://doi.org/10.3390/vision9020037","url":null,"abstract":"<p><p>Both voluntary mental imagery and dream imagery involve multisensory representations without externally present stimuli that can be categorized as offline perceptions. Due to common mechanisms, correlations between multisensory dream imagery profiles and multisensory voluntary mental imagery profiles were hypothesized. In a sample of 226 participants, correlations within the respective state of consciousness were significantly bigger than across, favouring two distinct networks. However, the association between the vividness of voluntary mental imagery and vividness of dream imagery was moderated by the frequency of dream recall and lucid dreaming, suggesting that both networks become increasingly similar when higher metacognition is involved. Additionally, the vividness of emotional and visual imagery was significantly higher for dream imagery than for voluntary mental imagery, reflecting the immersive nature of dreams and the continuity of visual dominance while being awake and asleep. In contrast, the vividness of auditory, olfactory, gustatory, and tactile imagery was higher for voluntary mental imagery, probably due to higher cognitive control while being awake. Most results were replicated four weeks later, weakening the notion of state influences. Overall, our results indicate similarities between dream imagery and voluntary mental imagery that justify a common classification as offline perception, but also highlight important differences.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-Wavelength and Infrared Autofluorescence Imaging in Pachychoroid Neovasculopathy. 厚脉络膜血管病的短波长和红外自身荧光成像。
Vision (Switzerland) Pub Date : 2025-04-21 DOI: 10.3390/vision9020038
Norihiko Nakagawa, Takuya Shunto, Issei Nishiyama, Kohei Maruyama, Miki Sawa
{"title":"Short-Wavelength and Infrared Autofluorescence Imaging in Pachychoroid Neovasculopathy.","authors":"Norihiko Nakagawa, Takuya Shunto, Issei Nishiyama, Kohei Maruyama, Miki Sawa","doi":"10.3390/vision9020038","DOIUrl":"https://doi.org/10.3390/vision9020038","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this paper is to investigate the relationship between short-wavelength autofluorescence (SWAF) and infrared autofluorescence (IRAF) patterns in pachychoroid neovasculopathy (PNV) with serous retinal detachment (SRD).</p><p><strong>Methods: </strong>This study used an observational case series of 62 eyes of 58 consecutive patients diagnosed with symptomatic PNV from January 2019 and October 2021 at a single institution. SWAF and IRAF patterns were analyzed with disease chronicity, and autofluorescence changes in macular neovascularization (MNV) were assessed in two images.</p><p><strong>Results: </strong>SWAF patterns and the mean duration of symptoms were as follows: blocked (15 eyes, 24%), 1.0 months; mottled (8 eyes, 13%), 2.8 months; hyper (24 eyes, 39%), 5.0 months; hyper/hypo (10 eyes, 16%), 7.0 months; descending tract (5 eyes, 8%), 12.0 months (<i>p</i> < 0.01). IRAF patterns and the mean duration of symptoms were as follows: blocked (17 eyes, 27%), 1.0 months; hyper (22 eyes, 35%), 4.0 months; mixed/hyper dominant (9 eyes, 15%), 5.0 months; mixed/hypo dominant (9 eyes, 15%), 6.8 months; descending tract (5 eyes, 8%), 12.0 months (<i>p</i> < 0.01). Abnormal autofluorescence corresponding to MNV lesion was seen in 34 eyes (55%) with SWAF and 59 eyes (95%) with IRAF (<i>p</i> < 0.01).</p><p><strong>Conclusions: </strong>SWAF and IRAF show multiple patterns and are related to disease chronicity in symptomatic PNV. IRAF could be helpful in detecting the lesion of MNV.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Anxiety Sensitivity, Emotional States, and Dry Eye Disease Symptom Severity: A Cross-Sectional Study. 焦虑敏感性、情绪状态与干眼病症状严重程度的关系:一项横断面研究
Vision (Switzerland) Pub Date : 2025-04-18 DOI: 10.3390/vision9020036
Marko Toth, Nataša Jokić-Begić, Sandro Krašić
{"title":"The Relationship Between Anxiety Sensitivity, Emotional States, and Dry Eye Disease Symptom Severity: A Cross-Sectional Study.","authors":"Marko Toth, Nataša Jokić-Begić, Sandro Krašić","doi":"10.3390/vision9020036","DOIUrl":"https://doi.org/10.3390/vision9020036","url":null,"abstract":"<p><p>Dry eye disease (DED) is often comorbid with psychiatric conditions and psychological disturbances like anxiety and depression. The psychological symptoms are mostly considered to be a consequence of DED or a side-effect of medication. However, the possible psychological etiology of DED is seldom explored. This study explores the relationship between anxiety sensitivity (AS), unpleasant emotional states, and the severity of DED symptoms in a healthy general population sample in Croatia. A total of 766 adults (62.27% females) aged between 18 and 88 years completed an online survey consisting of the Ocular Surface Disease Index (OSDI), Anxiety Sensitivity Index (ASI), and Depression Anxiety Stress Scales (DASS21) together with socio-demographic data. The results revealed significant positive correlations between ASI, emotional states, and OSDI (r = 0.25-0.29, <i>p</i> < 0.01). Mediation analysis showed that DASS21 significantly mediates the relationship between ASI and OSDI (B = 0.1, CI = [0.004, 0.2]). Highly anxiety sensitive people are more sensitive to DED symptoms, which additionally increases in a state of emotional stress. Thus, DED symptoms are perceived more intensely and frequently than in less sensitive people. Understanding these associations is crucial for comprehensive DED management, indicating potential benefits from addressing psychological health in DED patients and eye health in psychiatric patients.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Therapeutic Approaches for Treatment of Diabetic Retinopathy and Age-Related Macular Degeneration. 治疗糖尿病视网膜病变和老年性黄斑变性的新方法。
Vision (Switzerland) Pub Date : 2025-04-17 DOI: 10.3390/vision9020035
Deokho Lee, Soo Jin Kim, Junyeop Lee
{"title":"Novel Therapeutic Approaches for Treatment of Diabetic Retinopathy and Age-Related Macular Degeneration.","authors":"Deokho Lee, Soo Jin Kim, Junyeop Lee","doi":"10.3390/vision9020035","DOIUrl":"https://doi.org/10.3390/vision9020035","url":null,"abstract":"<p><p>Retina, a light-sensitive layer of tissue of the eye, requires high levels of oxygen for its physiology. Retinal ischemia occurs due to inadequate supply of blood to the retina and choroid. Retinal ischemia is implicated in the development or progression of many ocular diseases, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). To date, anti-vascular endothelial growth factor (VEGF) treatment has been widely used to manage neovascular diseases associated with retinal ischemia. Nonetheless, a substantial number of patients with DR or AMD still suffer from incomplete response and adverse effects related to its therapy with limitations. Therefore, research scientists have been developing and finding novel treatments to protect against or prevent vision loss in those diseases. In this review article, we summarize the recent novel therapeutic approaches for the treatment of ischemic retinopathy (e.g., cell therapy, advanced molecular targeting, or drug delivery). This summary enables further research to obtain more solid evidence of novel effective drug development in retinal ischemic diseases.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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