{"title":"A Simulated Visual Field Defect Impairs Temporal Processing: An Effect Not Modulated by Emotional Faces.","authors":"Mohammad Ahsan Khodami, Luca Battaglini","doi":"10.3390/vision9030079","DOIUrl":"10.3390/vision9030079","url":null,"abstract":"<p><p>Temporal processing is fundamental to visual perception, yet little is known about how it functions under compromised visual field conditions or whether emotional stimuli, as reported in the literature, can modulate it. This study investigated temporal resolution using a two-flash fusion paradigm with a static, semi-transparent overlay that degraded the right visual hemifield of opacity 0.60 and examined the potential modulatory effects of emotional faces. In Experiment 1, participants were asked to report if they perceived one or two flashes presented at either -6° (normal vision) or +6° (beneath a scotoma) across eight interstimulus intervals, ranging from 10 to 80 ms with a step size of 10 ms. Results showed significantly impaired temporal discrimination in the degraded vision condition, with elevated thresholds 52.29 ms vs. 34.78 ms and reduced accuracy, particularly at intermediate ISIs 30-60 ms. In Experiment 2, we introduced emotional faces before flash presentation to determine whether emotional content would differentially affect temporal processing. Our findings indicate that neither normal nor scotoma-impaired temporal processing was modulated by the specific emotional content (angry, happy, or neutral) of the facial primes.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Korolos Sawires, Brendan K Tao, Harrish Nithianandan, Larena Menant-Tay, Michael O'Connor, Peng Yan, Parnian Arjmand
{"title":"Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review of Ophthalmic Management and Treatment.","authors":"Korolos Sawires, Brendan K Tao, Harrish Nithianandan, Larena Menant-Tay, Michael O'Connor, Peng Yan, Parnian Arjmand","doi":"10.3390/vision9030078","DOIUrl":"10.3390/vision9030078","url":null,"abstract":"<p><p><b>Background:</b> Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare, life-threatening mucocutaneous disorders often associated with severe ophthalmic complications. Ocular involvement occurs in 50-68% of cases and can result in permanent vision loss. Despite this, optimal management strategies remain unclear, and treatment practices vary widely. <b>Methods:</b> A systematic review was conducted in accordance with PRISMA guidelines and prospectively registered on PROSPERO (CRD420251022655). Medline, Embase, and CENTRAL were searched from 1998 to 2024 for English-language studies reporting treatment outcomes for ocular SJS/TEN. <b>Results:</b> A total of 194 studies encompassing 6698 treated eyes were included. Best-corrected visual acuity (BCVA) improved in 52.2% of eyes, epithelial regeneration occurred in 16.8%, and symptom relief was reported in 26.3%. Common treatments included topical therapy (n = 1424), mucosal grafts (n = 1220), contact lenses (n = 1134), amniotic membrane transplantation (AMT) (n = 889), systemic medical therapy (n = 524), and punctal occlusion (n = 456). Emerging therapies included TNF-alpha inhibitors, anti-VEGF agents, photodynamic therapy, and 5-fluorouracil. <b>Conclusions:</b> Disease-stage-specific therapy is crucial in ocular SJS/TEN. Acute interventions such as AMT may prevent long-term complications, while chronic care targets structural and tear-film abnormalities. Further prospective studies are needed to standardize care and optimize visual outcomes.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raheem Remtulla, Patrik Abdelnour, Daniel R Chow, Andres C Ramos, Guillermo Rocha, Paul Harasymowycz
{"title":"Predicting Pattern Standard Deviation in Glaucoma: A Machine Learning Approach Leveraging Clinical Data.","authors":"Raheem Remtulla, Patrik Abdelnour, Daniel R Chow, Andres C Ramos, Guillermo Rocha, Paul Harasymowycz","doi":"10.3390/vision9030077","DOIUrl":"10.3390/vision9030077","url":null,"abstract":"<p><p>Visual field (VF) testing is crucial for the management of glaucoma. However, the process is often hindered by technician shortages and reliability issues. In this study, we leveraged machine learning to predict pattern standard deviation (PSD) using clinical inputs. This machine learning retrospective study used publicly accessible data from 743 eyes (541 glaucoma and 202 non-glaucoma controls). An automated neural network (ANN) model was trained using seven clinical input features: mean retinal nerve fiber layer (RNFL), IOP, patient age, CCT, glaucoma diagnosis, study protocol, and laterality. The ANN demonstrated efficient training across 1000 epochs, with consistent error reduction in training and test sets. Mean RMSEs were 1.67 ± 0.05 for training, and 2.27 ± 0.27 for testing. The <i>r</i> was 0.89 ± 0.01 for training, and 0.81 ± 0.04 for testing, indicating strong predictive accuracy with minimal overfitting. The LOFO analysis revealed that the primary contributors to PSD prediction were RNFL, CCT, IOP, glaucoma status, study protocol, and age, listed in order of significance. Our neural network successfully predicted PSD from RNFL and clinical data with strong performance metrics, in addition to demonstrating construct validity. This work demonstrates that neural networks hold the potential to predict or even generate VF estimations based solely on RNFL and clinical inputs.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modulating Multisensory Processing: Interactions Between Semantic Congruence and Temporal Synchrony.","authors":"Susan Geffen, Taylor Beck, Christopher W Robinson","doi":"10.3390/vision9030074","DOIUrl":"10.3390/vision9030074","url":null,"abstract":"<p><p>Presenting information to multiple sensory modalities often facilitates or interferes with processing, yet the mechanisms remain unclear. Using a Stroop-like task, the two reported experiments examined how semantic congruency and incongruency in one sensory modality affect processing and responding in a different modality. Participants were presented with pictures and sounds simultaneously (Experiment 1) or asynchronously (Experiment 2) and had to respond whether the visual or auditory stimulus was an animal or vehicle, while ignoring the other modality. Semantic congruency and incongruency in the unattended modality both affected responses in the attended modality, with visual stimuli having larger effects on auditory processing than the reverse (Experiment 1). Effects of visual input on auditory processing decreased under longer SOAs, while effects of auditory input on visual processing increased over SOAs and were correlated with relative processing speed (Experiment 2). These results suggest that congruence and modality both impact multisensory processing.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lionel Moiroud, Ana Moscoso, Eric Acquaviva, Alexandre Michel, Richard Delorme, Maria Pia Bucci
{"title":"Gaze Dispersion During a Sustained-Fixation Task as a Proxy of Visual Attention in Children with ADHD.","authors":"Lionel Moiroud, Ana Moscoso, Eric Acquaviva, Alexandre Michel, Richard Delorme, Maria Pia Bucci","doi":"10.3390/vision9030076","DOIUrl":"10.3390/vision9030076","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this preliminary study was to explore the visual attention in children with ADHD using eye-tracking, and to identify a relevant quantitative proxy of their attentional control.</p><p><strong>Methods: </strong>Twenty-two children diagnosed with ADHD (aged 7 to 12 years) and their 24 sex-, age-matched control participants with typical development performed a visual sustained-fixation task using an eye-tracker. Fixation stability was estimated by calculating the bivariate contour ellipse area (BCEA) as a continuous index of gaze dispersion during the task.</p><p><strong>Results: </strong>Children with ADHD showed a significantly higher BCEA than control participants (<i>p</i> < 0.001), reflecting their increased gaze instability. The impairment in gaze fixation persisted even in the absence of visual distractors, suggesting intrinsic attentional dysregulation in ADHD.</p><p><strong>Conclusions: </strong>Our results provide preliminary evidence that eye-tracking coupled with BCEA analysis, provides a sensitive and non-invasive tool for quantifying visual attentional resources of children with ADHD. If replicated and extended, the increased use of gaze instability as an indicator of visual attention in children could have a major impact in clinical settings to assist clinicians. This analysis focuses on overall gaze dispersion rather than fine eye micro-movements such as microsaccades.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Brandão Fantozzi, Letícia Margaria Peres, Jogi Suda Neto, Cinara Cássia Brandão, Rodrigo Capobianco Guido, Rubens Camargo Siqueira
{"title":"A Comparative Study Between Clinical Optical Coherence Tomography (OCT) Analysis and Artificial Intelligence-Based Quantitative Evaluation in the Diagnosis of Diabetic Macular Edema.","authors":"Camila Brandão Fantozzi, Letícia Margaria Peres, Jogi Suda Neto, Cinara Cássia Brandão, Rodrigo Capobianco Guido, Rubens Camargo Siqueira","doi":"10.3390/vision9030075","DOIUrl":"10.3390/vision9030075","url":null,"abstract":"<p><p>Recent advances in artificial intelligence (AI) have transformed ophthalmic diagnostics, particularly for retinal diseases. In this prospective, non-randomized study, we evaluated the performance of an AI-based software system against conventional clinical assessment-both quantitative and qualitative-of optical coherence tomography (OCT) images for diagnosing diabetic macular edema (DME). A total of 700 OCT exams were analyzed across 26 features, including demographic data (age, sex), eye laterality, visual acuity, and 21 quantitative OCT parameters (Macula Map A X-Y). We tested two classification scenarios: binary (DME presence vs. absence) and multiclass (six distinct DME phenotypes). To streamline feature selection, we applied paraconsistent feature engineering (PFE), isolating the most diagnostically relevant variables. We then compared the diagnostic accuracies of logistic regression, support vector machines (SVM), K-nearest neighbors (KNN), and decision tree models. In the binary classification using all features, SVM and KNN achieved 92% accuracy, while logistic regression reached 91%. When restricted to the four PFE-selected features, accuracy modestly declined to 84% for both logistic regression and SVM. These findings underscore the potential of AI-and particularly PFE-as an efficient, accurate aid for DME screening and diagnosis.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Assaf Kratz, Tom Kornhauser, Eyal Walter, Ran Abuhasira, Ivan Goldberg, Aviel Hadad
{"title":"Effect of Acetazolamide on Intraocular Pressure After Uneventful Phacoemulsification Using an Anterior Chamber Maintainer.","authors":"Assaf Kratz, Tom Kornhauser, Eyal Walter, Ran Abuhasira, Ivan Goldberg, Aviel Hadad","doi":"10.3390/vision9030073","DOIUrl":"10.3390/vision9030073","url":null,"abstract":"<p><p><b>Background:</b> Transient intraocular pressure (IOP) elevations frequently occur after cataract surgery and may raise concerns, especially in patients susceptible to glaucomatous damage or pressure-related complications. These IOP spikes have also been linked to postoperative discomfort and headache. Oral acetazolamide is often used prophylactically, despite its known systemic side effects. <b>Objectives:</b> To evaluate the clinical benefit of routine prophylactic oral acetazolamide in reducing IOP after uncomplicated phacoemulsification performed with an anterior chamber maintainer (ACM). <b>Methods:</b> In this retrospective case-control study, 196 eyes from 196 patients were included. All underwent standard phacoemulsification with an ACM. Patients either received oral acetazolamide postoperatively (<i>n</i> = 98) or no IOP-lowering medication (n = 98). IOP was measured preoperatively, and on postoperative days one and seven. <b>Results:</b> On day one, mean IOP was 14.0 ± 3.8 mmHg in the acetazolamide group versus 15.4 ± 3.8 mmHg in controls (<i>p</i> < 0.005). By day seven, IOP was identical in both groups (13.5 mmHg), with no statistically significant difference (<i>p</i> = 0.95). No participant in either group reported headache or serious adverse effects, though 10% in the acetazolamide group experienced mild, transient systemic symptoms. <b>Conclusions:</b> In low-risk patients undergoing uneventful cataract surgery with ACM, routine use of oral acetazolamide yields only a modest, short-lived IOP reduction without evident clinical benefit. Its use may be unnecessary in this setting, though targeted prophylaxis could be considered for high-risk individuals.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Three-View Relative Pose Estimation Under Planar Motion Constraints.","authors":"Ziqin Dai, Weimin Lv, Liang Liu","doi":"10.3390/vision9030072","DOIUrl":"10.3390/vision9030072","url":null,"abstract":"<p><p>Vision-based relative pose estimation serves as a core technology for high-precision localization in autonomous vehicles and mobile platforms. To overcome the limitations of conventional three-view pose estimation methods that rely heavily on dense feature matching and incur high computational costs, this paper proposes an efficient three-point correspondence algorithm based on planar motion constraints. The method constructs trifocal tensor constraint equations and develops a linearized three-point solution framework, enabling rapid relative pose estimation using merely three corresponding points in three views. In simulation experiments, we systematically analyzed the robustness of the algorithm under complex conditions that included image noise, angular deviation, and vibration. The method was further validated in real-world scenarios using the KITTI public dataset. Experimental results demonstrate that under the condition of satisfying the planar motion assumption, the proposed method achieves significantly improved computational efficiency compared with traditional methods (including general three-view methods, two-view planar motion estimation methods, and classical two-view methods), with the single-solution time reduced by more than 80% compared to general three-view methods. In the public dataset, our algorithm achieves a median rotation estimation error of less than 0.0545 degrees and maintains a translation estimation error of less than 2.1319 degrees. The proposed method exhibits higher computational efficiency and better numerical stability compared to conventional algorithms. This research provides an effective pose estimation solution with real-time performance and high accuracy for planar motion platforms such as autonomous vehicles and indoor mobile robots, demonstrating substantial engineering application value.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Nusair, Hassan Asadigandomani, Hossein Farrokhpour, Fatemeh Moosaie, Zahra Bibak-Bejandi, Alireza Razavi, Kimia Daneshvar, Mohammad Soleimani
{"title":"Clinical Applications of Artificial Intelligence in Corneal Diseases.","authors":"Omar Nusair, Hassan Asadigandomani, Hossein Farrokhpour, Fatemeh Moosaie, Zahra Bibak-Bejandi, Alireza Razavi, Kimia Daneshvar, Mohammad Soleimani","doi":"10.3390/vision9030071","DOIUrl":"10.3390/vision9030071","url":null,"abstract":"<p><p>We evaluated the clinical applications of artificial intelligence models in diagnosing corneal diseases, highlighting their performance metrics and clinical potential. A systematic search was conducted for several disease categories: keratoconus (KC), Fuch's endothelial corneal dystrophy (FECD), infectious keratitis (IK), corneal neuropathy, dry eye disease (DED), and conjunctival diseases. Metrics such as sensitivity, specificity, accuracy, and area under the curve (AUC) were extracted. Across the diseases, convolutional neural networks and other deep learning models frequently achieved or exceeded established diagnostic benchmarks (AUC > 0.90; sensitivity/specificity > 0.85-0.90), with a particularly strong performance for KC and FECD when trained on consistent imaging modalities such as anterior segment optical coherence tomography (AS-OCT). Models for IK and conjunctival diseases showed promise but faced challenges in heterogeneous image quality and limited objective training criteria. DED and tear film models benefited from multimodal data yet lacked direct comparisons with expert clinicians. Despite high diagnostic precision, challenges from heterogeneous data, a lack of standardization in disease definitions, imaging acquisition, and model training remain. The broad implementation of artificial intelligence must address these limitations to improve eye care equity.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paula Yuri Sacai, Maria Cecília Saccomani Lapa, Rosana Fiorini Puccini, Nívea Nunes Ferraz
{"title":"Color Vision in Schoolchildren with Low Birth Weight and Those Born Full-Term with Appropriate Weight for Gestational Age.","authors":"Paula Yuri Sacai, Maria Cecília Saccomani Lapa, Rosana Fiorini Puccini, Nívea Nunes Ferraz","doi":"10.3390/vision9030070","DOIUrl":"10.3390/vision9030070","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate color discrimination in schoolchildren with low birth weight (LBW) and those born full-term and at a weight appropriate for gestational age (AGA).</p><p><strong>Methods: </strong>LBW children aged 5-11 years and school-, grade-, sex-, and age-matched full-term (birth weight ≥ 2500 g) AGA controls from 14 randomly selected schools from a low-income region were tested. Examinations included visual acuity, ocular motility, and color vision testing using the Farnsworth D-15 test. Color score and interocular color score difference (ICD) were compared between the groups. Multiple logistic regression was used to analyze associations between color vision deficit and group, adjusting for age, sex, visual acuity, strabismus, and amblyopia.</p><p><strong>Results: </strong>A total of 291 LBW children (age = 8.5 ± 1.3 yrs; 55.7% females) and 265 AGA children (age = 8.5 ± 1.4 yrs; 56.2% females) were examined. Dyschromatopsia was detected in 10.3% of LBW and 7.9% of AGA children, primarily involving tritan and non-specific defects. Color scores were comparable between the groups, and color deficit was significantly associated with younger age and worse visual acuity. The ICD was statistically larger (<i>p</i> = 0.004) in the LBW group, in which the frequencies of strabismus and amblyopia were also higher.</p><p><strong>Conclusions: </strong>Most LBW children demonstrated normal color discrimination, but their interocular color score difference was larger than that of AGA children.</p>","PeriodicalId":36586,"journal":{"name":"Vision (Switzerland)","volume":"9 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}