Eastern Journal of Medical Sciences最新文献_第9页

THE ROLE OF GLUTATHIONE IN MALE INFERTILITY 谷胱甘肽在男性不育中的作用

Eastern Journal of Medical Sciences Pub Date : 2019-03-15 DOI: 10.32677/ejms.2018.v04.i01.005

M. ., M. –

{"title":"THE ROLE OF GLUTATHIONE IN MALE INFERTILITY","authors":"M. ., M. –","doi":"10.32677/ejms.2018.v04.i01.005","DOIUrl":"https://doi.org/10.32677/ejms.2018.v04.i01.005","url":null,"abstract":"Background: Numerous research studies have attempted to determine the causes of male infertility with the objective of developing therapeutic approaches to effectively improve various semen parameters. Aim: The presented intervention is a quantitative approach that categorically assesses the therapeutic advantage of oral GSH (glutathione) administration on various semen parameters including sperm concentration, morphology, and motility in infertile males. Methods: The prospective placebo-controlled study included 101 infertile adult males through random selection between the timeframe of Jan 2017 to Mar 2018. We selected total 101 subjects who did not experience any chronic disease of the reproductive system and exhibited normal female factor. GSH oral therapy was administered between 0 to 6 months, 51 patients received GSH therapy and 50 patients received placebo in the form of glucose sachets. At the time of 0, 3 and 6 months, the blood and semen samples were taken for analyses for treatment and placebo groups. Results: The findings recorded at 0 weeks, 3 months, and 6 months interval revealed a significant p-value. At 0 week, there wasn’t any statistical significance for the results while at 3 months, GSH value was 4.55 mg/dl for GSH group therapy in comparison for 1.55 mg/dl for placebo group which was statistically significant. Conclusion: The study findings revealed a strong positive relationship between oral GSH therapy and the selected sperm parameters.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129718202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ASSOCIATION BETWEEN BODY MASS INDEX AND MENISCAL TEARS REQUIRING SURGERY 体重指数与半月板撕裂需要手术之间的关系

Eastern Journal of Medical Sciences Pub Date : 2019-03-15 DOI: 10.32677/EJMS.2019.V04.I01.001

V. Kızılgöz, G. R. Ulusoy, H. Aydin, K. Yildiz, T. Çeti̇n, Multehan Evran

{"title":"ASSOCIATION BETWEEN BODY MASS INDEX AND MENISCAL TEARS REQUIRING SURGERY","authors":"V. Kızılgöz, G. R. Ulusoy, H. Aydin, K. Yildiz, T. Çeti̇n, Multehan Evran","doi":"10.32677/EJMS.2019.V04.I01.001","DOIUrl":"https://doi.org/10.32677/EJMS.2019.V04.I01.001","url":null,"abstract":"Aim: This study evaluated the association between body mass index (BMI) and operated patients due to meniscal injuries of the knee. We also investigated the influence of BMI on meniscal tears with regard to age. Methods: We investigated 104 patients who had surgery for meniscal injuries and 111 patients who had knee magnetic resonance imaging (MRI) with no prior history of meniscal surgery. The relationship between BMI and meniscal injuries which required meniscal surgery was evaluated by independent samples T-test. A cutoff BMI value has been tried to find out by receiver operating characteristics (ROC). The odds ratio has been calculated with regard to this cutoff value. Patients were classified into three age groups ≤30, 31–50 and ≥51 years old. Chi-square was used to determine whether age affected the BMI relationship with meniscal injuries which required surgery. Results: BMI values were significantly higher in surgical patients compared to controls (p = 0.005). To compare surgical and non-surgical patients, ROC analysis was used and area under curve (AUC) value was calculated as 0.605. A BMI value of 27.90 had the highest specificity (92.0%) and sensitivity (40.4%), and the odds ratio calculated by Pearson chi-square was 3,08 for this BMI value. The most significant difference in BMI between surgical and non-surgical patients was observed in the 31–50 age group (p = 0.007). There was no significant difference in BMI between surgical and non-surgical patients in the <30 age group (p=0,404). Conclusion: Higher BMI increases the risk of meniscal tears requiring surgery, especially in the 31–50 age groups. Patients might benefit from weight regulation since BMI is thought to be an important modifiable risk factor for meniscal tears.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124452160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phenotypic detection of Metallo Beta Lactamase Producing Pseudomonas aeruginosa among Clinical Isolates from the intensive care unit of a tertiary care centre 某三级医疗中心重症监护室临床分离株中产生金属β -内酰胺酶的铜绿假单胞菌的表型检测

Eastern Journal of Medical Sciences Pub Date : 2018-12-31 DOI: 10.32677/EJMS.2018.V03.I04.003

M. S. Deopa, R. Goyal, Mukesh Kumar, A. Kumar

{"title":"Phenotypic detection of Metallo Beta Lactamase Producing Pseudomonas aeruginosa among Clinical Isolates from the intensive care unit of a tertiary care centre","authors":"M. S. Deopa, R. Goyal, Mukesh Kumar, A. Kumar","doi":"10.32677/EJMS.2018.V03.I04.003","DOIUrl":"https://doi.org/10.32677/EJMS.2018.V03.I04.003","url":null,"abstract":"Background: Pseudomonas aeruginosa is an opportunistic pathogenic bacterium responsible for both, acute and chronic infection, causing serious infections in patients who are mechanically ventilated individuals, who are immunocompromised, and patients with malignancies or HIV infection. Objectives: The phenotypic screening of metallo beta-lactamases (MBL) in strains of Pseudomonas aeruginosa resistant to imipenem. Material and Methods: The study was carried out in the department of Microbiology, in a medical hospital, Bareilly, over a period 18 months from January 2013 to June 2014. A total of 103 Pseudomonas aeruginosa isolated from sputum, broncho alveolar lavage (BAL), urine, pus and blood from critically ill patients admitted in the intensive care unit of a tertiary care centre. Strain of P. aeruginosa resistant to imipenem, were tested for metallo beta-lactamase production by phenotypic methods. Result: Out of 103 Pseudomonas aeruginosa, 48 strains were found imipenem resistant, of which 43(89.6%) were MBL positive by imipenem -EDTA combined disc test and the rest 35(72.9%) were by modified Hodge test. Conclusion: Imipenem – EDTA combined disc test found to be the best phenotypic method for detection of MBL. The appearance of the MBL and their spread among bacterial pathogens is a matter of concern with regard to the future of antimicrobial therapy. Both the methods are simple and one of these phenotypic methods can be easily incorporated in routine lab procedures to detect MBL.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128266345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigational Biomarkers in Patients with Chronic Renal Failure 慢性肾衰竭患者的生物标志物研究

Eastern Journal of Medical Sciences Pub Date : 2018-12-31 DOI: 10.32677/ejms.2018.v03.i04.002

Derya Sahin ., H. .

引用次数: 0

Prediction of Low Factor V Levels in Patients with Herbal Medicine Related Acute Liver Injury 中草药相关性急性肝损伤患者低因子V水平的预测

Eastern Journal of Medical Sciences Pub Date : 2018-12-31 DOI: 10.32677/ejms.2018.v03.i04.005

A. ., M. –, Selahattin Vural ., Tugrul Kesicioglu ., Raziye Turan .

引用次数: 1

Histopathological Examination of Dyspeptic Patients With and Without Hiatal Hernia 有无裂孔疝的消化不良患者的组织病理学检查

Eastern Journal of Medical Sciences Pub Date : 2018-09-15 DOI: 10.32677/EJMS.2018.V03.I03.004

S. Vural, Bekir Poyraz, A. Dulger

{"title":"Histopathological Examination of Dyspeptic Patients With and Without Hiatal Hernia","authors":"S. Vural, Bekir Poyraz, A. Dulger","doi":"10.32677/EJMS.2018.V03.I03.004","DOIUrl":"https://doi.org/10.32677/EJMS.2018.V03.I03.004","url":null,"abstract":"Background: Hiatal hernia with dyspeptic complaints is a severe disease which disturbs the quality of life. Pathological findings in endoscopy are an important factor in the treatment of these patients. Objective: To investigate the histopathological differences related to hiatal hernia in dyspeptic patients. Material and Methods: A retrospective study was conducted of 116 patients with dyspeptic complaints. The patients were divided into two groups according to the presence of hiatal hernia. Biochemical tests and endoscopic biopsy results of these groups were compared. Results: The mean age of our study population was 52.4 years where, 50% were male and 50% were female. Hiatal hernia was found in 44.8% of the patients and 22.4% of the patients had intestinal metaplasia. The rate of intestinal metaplasia was found to be statistically lower in the hiatal hernia group (p=0.011). Conclusion: Intestinal metaplasia is less frequently found in patients with hiatal hernias in our study; it may be attributed to the fact that these patients had earlier dyspeptic complaints and therefore, earlier medical treatment and earlier initiation of a protective gastric diet.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114725182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Validation of a Scale for Measuring Family Happiness 家庭幸福量表的开发与验证

Eastern Journal of Medical Sciences Pub Date : 2018-09-15 DOI: 10.32677/EJMS.2018.V03.I03.002

Kenan Tastan, Pinar Fakirullah, C. Ardic

引用次数: 0

Comparative evaluation of the fit of ceramic inlay restorations fabricated with heat-press technique and CAD/CAM systems: A preliminary study 热压技术与CAD/CAM系统制备陶瓷镶嵌体修复体配合度的比较研究

Eastern Journal of Medical Sciences Pub Date : 2018-09-15 DOI: 10.32677/EJMS.2018.V03.I03.005

Merve Benli

{"title":"Comparative evaluation of the fit of ceramic inlay restorations fabricated with heat-press technique and CAD/CAM systems: A preliminary study","authors":"Merve Benli","doi":"10.32677/EJMS.2018.V03.I03.005","DOIUrl":"https://doi.org/10.32677/EJMS.2018.V03.I03.005","url":null,"abstract":"Objective: The objective of this in-vitro study was to evaluate the marginal and internal fit of a lithium disilicate inlays fabricated by two CAD/CAM systems (extra-oral and intra-oral scanning), and conventional heat-press technique. Materials and methods: Mandibular first molars were used for inlay restorations in a typodont model. Three groups (n=12 each) of inlays were fabricated by Computer Aided Design/ Computer Aided Manufacturing (CAD/CAM) technology using intraoral and extraoral scanning devices, and conventional heat-press method. Replica technique was used to assess the discrepancies. Internal and marginal gaps were measured at 4 points on each side with stereomicroscope at 200x magnification. One-way variance analysis test (ANOVA) and paired-samples t-test were used for analyzing the results. Results: The fit values were statistically significantly influenced by the production method in total discrepancy comparisons (p= .000). Intraoral scanner group demonstrated the lowest marginal and internal gap values whereas conventional heat-press group showed the highest results. Statistically significant differences were found for fit values with respect to the groups (p<.001). Conclusion: Within the limitations of the study, restorations fabricated via complete digital workflow demonstrated better marginal and internal accuracy than silicone impressions with conventional heat-press technique.‎","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131678187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Assessment of Knowledge and Behaviour of Pharmacy Services Students in Vocational School Of Health Services for Rational Drug Use 高职卫生服务专业药学专业学生合理用药知识与行为评价

Eastern Journal of Medical Sciences Pub Date : 2018-09-15 DOI: 10.32677/ejms.2018.v03.i03.001

Sultan Mehtap Buyuker, Gamze Odabaşı

{"title":"Assessment of Knowledge and Behaviour of Pharmacy Services Students in Vocational School Of Health Services for Rational Drug Use","authors":"Sultan Mehtap Buyuker, Gamze Odabaşı","doi":"10.32677/ejms.2018.v03.i03.001","DOIUrl":"https://doi.org/10.32677/ejms.2018.v03.i03.001","url":null,"abstract":"Objective: To evaluate the knowledge and behaviour of the students about the rational drug use studying in the pharmacy services program in Vocational School of Health Services (VSHS). Methods: This cross-sectional study, conducted between 2017 October and 2018 March, was conducted on the first and second year students of a University VSHS Pharmacy Services Program. In this study, questionnaire was applied to 115 students to assess their knowledge and behaviour about the rational drug use. Results: The average age of the 115 students who participated in the study was 19.54±1.79 years. Among the causes of drug use by the participants, influenza (64.6%) was in the first place. Participants were asked to propose medication competence and 30.7% of the participants stated that they suggested prescribed drugs. The prominence of commercial advertising was questioned and 58.8% of the participants said they did not use the advertised products. Conclusion: In our study, it was seen that pharmacy technicians studying in pharmacy services program did not have sufficient knowledge about rational drug use. The content of training programs should include more information on rational drug use.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132639089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Pre-operative Serum CEA and CA19-9 Levels in Patients with Gastric Cancer: A Single-Center Experience 胃癌患者术前血清CEA和CA19-9水平:单中心研究

Eastern Journal of Medical Sciences Pub Date : 2018-09-15 DOI: 10.32677/EJMS.2018.V03.I03.003

I. Atak, S. F. Yeğen, T. Atak, A. Guler, L. Polat, Veysi Samsa

{"title":"Pre-operative Serum CEA and CA19-9 Levels in Patients with Gastric Cancer: A Single-Center Experience","authors":"I. Atak, S. F. Yeğen, T. Atak, A. Guler, L. Polat, Veysi Samsa","doi":"10.32677/EJMS.2018.V03.I03.003","DOIUrl":"https://doi.org/10.32677/EJMS.2018.V03.I03.003","url":null,"abstract":"Introduction: To evaluate the preoperative CEA and CA19-9 levels and their association with clinicopathologic features and mortality. Methods: This retrospective study was conducted on patients who underwent gastric surgery due to gastric adenocarcinoma from 2008 to 2015. Preoperative serum CEA and CA19-9 levels were compared according to the TNM classification and survival data were compared. Results: A total of 335 patients were included in the study with the mean age of 66.1±11.0 years. CEA and CA19-0 positivity were 29.1% and 28.1%, respectively. According to the CEA groups, T stages of the cases were statistically significant (p = 0.013). The rates of T stage 1 in group 1 (CEA positive) were significantly higher than the group 2 (CEA negative) (p=0.007). According to the CA19-9 positivity; rate of stage 2 was significantly higher in the group 1 (CA19-9 positive) (p=0.001); however, rates of stage 2 and 3 were significantly higher in the group 2 (CA19-9 negative) (p=0.004 and p=0.007, respectively). Mortality information could be accessed for 309 cases and 108 deaths (36%) were observed. The mean survival time was 45.21±2.42 months. No significant difference was observed between the groups (p>0.05). Conclusion: Patients with higher levels of CEA and CA19-9 seem to have higher grades of gastric cancer. However, CEA and CA19-9 level does not seem to be in association in our study population.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127551196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1