有无裂孔疝的消化不良患者的组织病理学检查

S. Vural, Bekir Poyraz, A. Dulger
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引用次数: 0

摘要

背景:裂孔疝伴消化不良主诉是一种严重影响生活质量的疾病。内窥镜检查的病理结果是治疗这些患者的重要因素。目的:探讨消化不良患者裂孔疝的病理组织学差异。材料与方法:对116例消化不良患者进行回顾性研究。根据有无裂孔疝分为两组。比较各组生化指标和内镜活检结果。结果:我们研究人群的平均年龄为52.4岁,其中男性占50%,女性占50%。裂孔疝发生率为44.8%,肠化生发生率为22.4%。裂孔疝组肠上皮化生发生率明显低于裂孔疝组(p=0.011)。结论:本组裂孔疝患者肠化生发生率较低;这可能是由于这些患者有较早的消化不良症状,因此较早接受治疗和较早开始保护性胃饮食。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Histopathological Examination of Dyspeptic Patients With and Without Hiatal Hernia
Background: Hiatal hernia with dyspeptic complaints is a severe disease which disturbs the quality of life. Pathological findings in endoscopy are an important factor in the treatment of these patients. Objective: To investigate the histopathological differences related to hiatal hernia in dyspeptic patients. Material and Methods: A retrospective study was conducted of 116 patients with dyspeptic complaints. The patients were divided into two groups according to the presence of hiatal hernia. Biochemical tests and endoscopic biopsy results of these groups were compared. Results: The mean age of our study population was 52.4 years where, 50% were male and 50% were female. Hiatal hernia was found in 44.8% of the patients and 22.4% of the patients had intestinal metaplasia. The rate of intestinal metaplasia was found to be statistically lower in the hiatal hernia group (p=0.011). Conclusion: Intestinal metaplasia is less frequently found in patients with hiatal hernias in our study; it may be attributed to the fact that these patients had earlier dyspeptic complaints and therefore, earlier medical treatment and earlier initiation of a protective gastric diet.
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