Eastern Journal of Medical Sciences最新文献

Bacteriological profile and their antimicrobial susceptibility pattern among clinical suspected adult septicemia admitted patients: A study from tertiary care and teaching hospital 临床疑似败血症成人患者的细菌学特征及其抗菌药敏感性模式：一项来自三级医疗教学医院的研究

Eastern Journal of Medical Sciences Pub Date : 2024-05-07 DOI: 10.32677/ejms.v9i1.4530

K. Nirmal, Priyanka Gupta, Nadeem Ahmad, Smita Nath, Narendra Pal Singh, Shukla Das

{"title":"Bacteriological profile and their antimicrobial susceptibility pattern among clinical suspected adult septicemia admitted patients: A study from tertiary care and teaching hospital","authors":"K. Nirmal, Priyanka Gupta, Nadeem Ahmad, Smita Nath, Narendra Pal Singh, Shukla Das","doi":"10.32677/ejms.v9i1.4530","DOIUrl":"https://doi.org/10.32677/ejms.v9i1.4530","url":null,"abstract":"Objectives: The objective of this study is to determine the bacteriological profile and their antimicrobial susceptibility pattern among clinically suspected adult septicemia admitted patients and to study the correlation between the clinical presentation and inflammatory biomarkers (C-reactive protein [CRP] and Procalcitonin [PCT]) in the final outcomes of nosocomial sepsis in adult septicemia patients. Material and Methods: This is a descriptive cross-sectional study of 1-year duration from November 2022 to November 2023. The study has been approved from the Institutional Ethical Committee. Adult patients with a clinical suspected diagnosis of sepsis were admitted to the medicine ward of the tertiary hospital. Blood samples of adult sepsis suspected patients samples were taken for as a part of septicemia screening. Blood culture and sensitivity were performed according to standard guidelines. The sepsis inflammatory prognostic markers CRP and PCT test were evaluated according to manufactures instruction. Results: Out of 300 clinically suspected adult septicemia patients, 93 (31%) patients were isolated culture-positive sepsis while 207 (69%) patients were culture-negative sepsis. Gram-positive organisms were more (69%) as compared to Gram-negative organisms (31%). Staphylococcus aureus was predominant among Gram-positive organisms while Acinetobacter baumanii complex (9%) followed by Enterobacter spp. (8%) isolated in Gram-negative bacilli. Culture-positive sepsis patients have CRP level ≥3.2 mg/dL (80%) and the majority (80%) of these patients have reactive PCT. Conclusions: Successful treatment of bloodstream infection depends on early diagnosis and appropriate use of antimicrobial agents. Rapid identification results and antimicrobial susceptibility tests are essential for guiding clinicians in the selection of the most appropriate treatment for patients with bloodstream infections.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular genetic analysis of cytosine-adenine-guanine repeats in huntingtin gene 亨廷基因中胞嘧啶-腺嘌呤-鸟嘌呤重复序列的分子遗传分析

Eastern Journal of Medical Sciences Pub Date : 2024-05-07 DOI: 10.32677/ejms.v9i1.4501

Pankaj Gadhia, Avani Sangani, S. Vaniawala

引用次数: 0

Eastern Journal of Medical Sciences Pub Date : 2024-03-16 DOI: 10.32677/ejms.v8i4.4451

A. Lutf, Anwar Ibrahi Joudeh, Salah M Mehdi

{"title":"IgG4-related disease presenting as a pancreatic mass: A case report","authors":"A. Lutf, Anwar Ibrahi Joudeh, Salah M Mehdi","doi":"10.32677/ejms.v8i4.4451","DOIUrl":"https://doi.org/10.32677/ejms.v8i4.4451","url":null,"abstract":"Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognized fibroinflammatory condition with characteristic clinical, serological, and histopathological features. It might involve any organ in the body with a special predilection for lymph nodes, salivary glands, the pancreas, and the retroperitoneum. Due to the non-specific features of the disease and the capability of mimicking many other medical conditions, the diagnosis of IgG4-RD could be delayed. Herin, we describe a case of a middle-aged man who presented with obstructive jaundice due to a pancreatic mass. Further evaluation revealed multiple cervical and inguinal lymphadenopathy, bilateral wedge-shaped lesions in the kidneys and substantial thickening of the aortic wall that was suggestive of aortitis/periaortitis. A histopathological examination of an inguinal lymph node showed increased infiltration of nodal immunoglobulin G4 (IgG4) plasma cells (>30/high-power field) with a high serum IgG4 immunoglobulin level. Based on that, the patient was diagnosed with IgG4-RD, and he was successfully treated with pulse steroid therapy with complete resolution of his symptoms and the radiological and laboratory findings. IgG4-RD is a protean condition with a large spectrum of clinical manifestations that could mimic many other serious medical conditions. Early recognition and management of immunosuppression are vital for complete recovery.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"100 s4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140236362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suprasellar granular cell tumor: A rare case report 星状上颗粒细胞瘤：罕见病例报告

Eastern Journal of Medical Sciences Pub Date : 2024-03-16 DOI: 10.32677/ejms.v8i4.4485

Vipal H Parmar, Prashant Mahendrabhai Parikh, Bhavana Asit Mehta, Sandip Chandrakant Shah, Ankita Girish Murnal

{"title":"Suprasellar granular cell tumor: A rare case report","authors":"Vipal H Parmar, Prashant Mahendrabhai Parikh, Bhavana Asit Mehta, Sandip Chandrakant Shah, Ankita Girish Murnal","doi":"10.32677/ejms.v8i4.4485","DOIUrl":"https://doi.org/10.32677/ejms.v8i4.4485","url":null,"abstract":"Granular cell tumor (GCT) originating from the sellar and suprasellar regions, specifically from the neurohypophysis, is a rare neoplasm. Symptomatic GCT of the neurohypophysis is exceedingly rare, being <70 cases described so far. GCTs predominantly exhibit benign behavior, while the malignancy rate remains at 2%. Imaging is quite unspecific and diagnosis is difficult to establish preoperatively. Histopathology and immunohistochemistry serve as the definitive diagnostic approach for GCTs and help in distinguishing GCT from other pituitary tumors, including pituitary adenoma, pituicytoma, and spindle cell oncocytoma. These tumors are resistant to radiotherapy and chemotherapy, necessitating surgical resection as the primary treatment modality. Due to the potential absence of distinct tumor masses and local tissue infiltration by tumor cells, complete excision is crucial, with resection extent extending beyond areas of infiltration. Here, we present a rare case of GCT originating from the posterior pituitary in the suprasellar region. On immunohistochemistry, tumor cells expressed diffusely thyroid transcription factor-1, S-100 protein, and vimentin confirming the diagnosis of supra-sellar GCT. The reported case is noteworthy for the rarity of the clinicopathological entity.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"57 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review exploring the effectiveness of Hypnotherapy as an intervention for the cessation of smoking in individual 探索催眠疗法作为个人戒烟干预措施的有效性的系统性综述

Eastern Journal of Medical Sciences Pub Date : 2024-02-29 DOI: 10.32677/ejms.v8i3.4197

Rimjhim Agrawal, Shania Aldons, Rabia Sabreen, Rekha Wagani

{"title":"A systematic review exploring the effectiveness of Hypnotherapy as an intervention for the cessation of smoking in individual","authors":"Rimjhim Agrawal, Shania Aldons, Rabia Sabreen, Rekha Wagani","doi":"10.32677/ejms.v8i3.4197","DOIUrl":"https://doi.org/10.32677/ejms.v8i3.4197","url":null,"abstract":"A significant number of individuals who smoke understand the risks of smoking but are unsuccessful when it comes to implementing smoking cessation. Hypnotherapy is often described as a tool that helps individuals shift their self-image from that of a smoker to a non-smoker. The purpose of this systematic review was to examine the status of existing research on the impact of hypnotherapy on smoking cessation in terms of type of hypnotherapy, type of application, relapse rate, duration of intervention, extent, and safety of smoking cessation, along the effectiveness in comparison with other pharmacological and non-pharmacological interventions. For this study, the authors used databases such as APA, Scopus, PubMed, JSTOR, and Frontiers for studies that used hypnotic interventions for smoking cessation. The Preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines were adhered to for screening of the research papers and finalizing of data, from which the PRISMA flowchart was constructed. The authors extracted data on the nature and characteristics of the studies, the types of interventions used [hypnotherapy as a sole intervention or paired with other interventions], characteristics of the sample population [sample size, control groups, and demographic details of the sample], duration of the interventions, and the method of assessment of smoking abstinence. The results show that there is inconclusive effect of hypnotherapy on smoking cessation in the target population. Hypnotherapy has an apparent effect on behavior formation and change; this review paper will consequently serve to provide a holistic understanding of smoking cessation and hypnotherapy as a tool for it.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"3 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140410502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Food microbiology 食品微生物学

Eastern Journal of Medical Sciences Pub Date : 2024-02-29 DOI: 10.32677/ejms.v8i3.4433

Sayan Bhattacharyya

{"title":"Food microbiology","authors":"Sayan Bhattacharyya","doi":"10.32677/ejms.v8i3.4433","DOIUrl":"https://doi.org/10.32677/ejms.v8i3.4433","url":null,"abstract":"Background: Food is imperative for continuation of life. However, it is also an important vehicle of entry of infections. Bacterial, viral and parasitic agents, causing these infections can all spread by food. Bacteria can produce many toxins and also be invasive sometimes, which can lead to diarrhoea and dysentery, respectively. This contamination takes place by risks like cooking food at improper temperature and keeping food open after cooking. These risks lead to various hazards. Also, microbes can help prepare different foods like fermented foods and kombucha tea. Modern society relies heavily on processed and ready-to eat foods, both of which can cause foodborne infections. Keeping all these things in mind, the science of food microbiology becomes very important in modern times. Aim: All these aspects of food microbiology and food safety have been discussed in this chapter. Objectives: Many points like food safety, cleanliness and other aspects like chilling of cooked food minimize risks of microbial food contamination and resultant hazards, have been elaborated upon. Methods: Scientific literature search was carried out to study the risk factors and related reports with respect to food microbiology, by food scientists and others. Results: Food contamination can be of microbial origin and a multitude of factors may lead to microbial contamination of food. These factors could be improper cooking, leaving cooked food uncovered, and other things. Conclusion: Food microbiology is a very important aspect of public health and quite neglected too. It should be given its due importance to mitigate microbial contamination of food and consequent foodborne infections.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"13 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140410215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An unusual presentation of epidermoid cyst in an adult male in India: A case report 一例不寻常的表皮样囊肿在印度的一个成年男性:一个病例报告

Eastern Journal of Medical Sciences Pub Date : 2023-07-24 DOI: 10.32677/ejms.v8i2.4115

H. Singh, S. Dua, A. Dhar, A. Goel, S. Mahajan, Priyanshi Srivastava

{"title":"An unusual presentation of epidermoid cyst in an adult male in India: A case report","authors":"H. Singh, S. Dua, A. Dhar, A. Goel, S. Mahajan, Priyanshi Srivastava","doi":"10.32677/ejms.v8i2.4115","DOIUrl":"https://doi.org/10.32677/ejms.v8i2.4115","url":null,"abstract":"The epidermoid cysts are true cysts that are often found in the face and less commonly in the trunk and back of the human body. These cysts often have a predilection toward the male gender with the third and fourth decades of age group. They generally arise from the follicular infundibulum, primarily due to plugging of the follicle. Often a part of genetic syndromes, they can also be post-traumatic where the ectodermal cells get stuck or reimplanted. Epidermoid cysts are often a slow-growing and painless lesion with few exceptions. The proper neurological examination, clinical examination, and investigations such as magnetic resonance imaging help in confirming the diagnosis and proceeding with the management. Clinically, epidermoid cysts may or may not present with the neurological impairment. The preferred intervention is total or subtotal resection with minimal chances of complications such as recurrence, swelling, and infection. However, these can very well be avoided by regular follow-up assessments. The clinical presentation in the lower back with massive dimensions is relatively uncommon, and therefore, authors have presented here an unusual case from the outpatient department of neurosurgery, where the patient presented with a large, soft, exophytic lesion at the level of (S4/S5), which gave rise to the suspicion of meningocele and meningomyelocele, but after complete local assessment and radiological investigations, it was diagnosed finally as an epidermoid cyst. Keeping in mind, the clinical profile, socioemographic factors, and metabolic profile, the intervention of surgical total resection was planned, and the patient was managed.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121772402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A holistic framework for interpreting positive clinical outcomes in biotechnology 解释生物技术中积极临床结果的整体框架

Eastern Journal of Medical Sciences Pub Date : 2023-07-23 DOI: 10.32677/ejms.v8i2.4022

Nikil Varma

引用次数: 0

Methods for detection of biofilms in bacteria and fungi 细菌和真菌中生物膜的检测方法

Eastern Journal of Medical Sciences Pub Date : 2023-07-20 DOI: 10.32677/ejms.v8i2.4156

Sayan Bhattacharya

引用次数: 0

Free gingival grafting technique for gingival recession coverage: A 6-month follow-up interventional study 游离牙龈移植技术修复牙龈萎缩:6个月随访的介入研究

Eastern Journal of Medical Sciences Pub Date : 2023-06-29 DOI: 10.32677/ejms.v8i2.4124

Poornima Rajendran, R. Namburi

{"title":"Free gingival grafting technique for gingival recession coverage: A 6-month follow-up interventional study","authors":"Poornima Rajendran, R. Namburi","doi":"10.32677/ejms.v8i2.4124","DOIUrl":"https://doi.org/10.32677/ejms.v8i2.4124","url":null,"abstract":"Background: Both the practitioner and the patient frequently deal with gingival recession. In Miller’s Classes I and II mandibular gingival recession, the goal of this study was to evaluate the predictability of the free gingival graft (FGG), as a single-step operation in terms of root coverage and esthetics. Materials and Methods: 10 patients between the ages of 25 and 50 who were sent to the Department of Periodontics (3 men and 7 women) made up the study group. There were a total of 14 mandibular recession sites that were chosen. Recession depth (RD), recession width, probing depth (PD), clinical attachment level (CAL), width of attached gingiva (WAG), and visual analog scale (VAS) were assessed at baseline, 3 months, and 6 months post-operatively. Results: The mean RD was 3.13±2.0 mm at the baseline and decreased to 0.80±0.78 mm after 6 months. At baseline, the VAS was 3.52±0.81, and at 6 months after surgery, it had improved to a mean of 6±2.14. From a baseline WAG of 0.35±0.38 to 2.83±0.68 mm, there wasa significant increase with p<0.0001. Six months after surgery, there was an increase in CAL, from 5.63±1.12 to 1.28±0.76 mm. In addition, PD improved from 1.98±0.54 to 0.97±0.36 mm. Conclusion: FGG showed statistically significant gain in recession coverage and had good esthetic score. The technique produced a reliable single-step gain in WAG as well as root coverage in cases of Miller’s Classes I and II gingival recession.","PeriodicalId":363370,"journal":{"name":"Eastern Journal of Medical Sciences","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134201248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0