Journal of Functional Foods最新文献

{"title":"Evaluation of swim bladder-derived oligopeptides on skin nutrition and health in vitro","authors":"Shi Zhihui ,&nbsp;Zheng Zhilong ,&nbsp;Zhang Yansheng ,&nbsp;Huang Kaiyue ,&nbsp;Bao Weiyang ,&nbsp;Qin Yanjie","doi":"10.1016/j.jff.2024.106500","DOIUrl":"10.1016/j.jff.2024.106500","url":null,"abstract":"<div><div>Human fibroblast cells (BJ cells) were used <em>in vitro</em> to study the skin-care effects of fish swim bladder oligopeptides (FSBOP). Wound healing results showed that cell migration was significantly enhanced in cells treated with 0.5 % FSBOP (<em>P</em> &lt; 0.05). SOD and GSH-Px activities in cells treated with 0.5 %, 1 % and 2 % FSBOP were significantly increased (<em>P</em> &lt; 0.05). In addition, 1 % vitamin E (VE) and fish collagen peptide (CP) significantly induced SOD and GSH-Px activitiy. The hydroxyproline (HYP) content increased after treatment with FSBOP, CP, and VE (<em>P</em> &lt; 0.05). The cells showed greater amounts of hyaluronic acid (HA) in the 1 % and 2 % FSBOP groups (<em>P</em> &lt; 0.05). The HA content in the 1 % VE and FSBOP groups was significantly higher (<em>P</em> &lt; 0.05). It was concluded that oligopeptides might be useful in the cosmetics industry as oligopeptides have good antioxidant, moisturizing, and anti-wrinkle effects, and promote wound repair.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106500"},"PeriodicalIF":3.8,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into inhibitory mechanisms: Unraveling the structure-activity relationship of dietary flavonoids on gut bacterial β-glucuronidase","authors":"Jialu Shen ,&nbsp;Qingyu Zhao ,&nbsp;Kai Zhang ,&nbsp;Junmin Zhang ,&nbsp;Huiyan Zhang","doi":"10.1016/j.jff.2024.106510","DOIUrl":"10.1016/j.jff.2024.106510","url":null,"abstract":"<div><div>Dietary flavonoids are regarded as potent inhibitors of gut bacterial β-glucuronidase (β-GUS), although the precise structure-activity relationship between dietary flavonoids and β-GUS remains elusive. In this study, 24 dietary flavonoids of 6 common different structural types were selected as model molecules to investigate this relationship through enzymatic inhibition kinetics and molecular docking simulations. The findings revealed that delphinidin (1) and baohuoside I (16) exhibited robust inhibitory activities, while the formation of ionic bond and hydrogen bonds was found to play crucial roles in these interactions. Moreover, the core structure, position, and quantity of hydroxyl groups; type and number of glycosyls, and the presence of isopentenyl group all played pivotal roles in influencing inhibitory activities against β-GUS derived from <em>Escherichia coli</em>. These results offer valuable insights into the relationship between flavonoid structure and enzyme inhibition, which could prove invaluable for the development of novel drugs and flavonoid dietary supplements.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106510"},"PeriodicalIF":3.8,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biologically synthesized 10-Hydroxy-2-Decenoic acid activates cornified envelope formation via PPARα signaling, and regulates oxidative respiratory chain to improve mitochondrial function","authors":"Chun-Ying Yuan,&nbsp;Su-Zhen Yang,&nbsp;Chun-Ming Gao,&nbsp;Tian-Ming Bai,&nbsp;Ting-Ting Han,&nbsp;Shan-Shan Jiang,&nbsp;San-Ling Liu,&nbsp;Kuan-Kuan Gao,&nbsp;Xin-Yu Mao,&nbsp;Hong Jiang,&nbsp;Yan Li","doi":"10.1016/j.jff.2024.106505","DOIUrl":"10.1016/j.jff.2024.106505","url":null,"abstract":"<div><div>10-Hydroxy-2-decenoic acid is a <em>trans</em>-unsaturated fatty acid exclusively found in royal jelly, known for its health and medical benefits. The current isolation and preparation methods have limitations such as low yield, high costs, difficult operation, and mixed products, which hinder its wider application. This study introduced P450 enzyme fusion gene into <em>S. cerevisiae</em> BY4741, then fermenting <em>trans</em>-2-decenoic acid could produce 10-Hydroxy-2-decenoic acid. With the biosynthesized 10-Hydroxy-2-decenoic acid, we explored its potential application in skin care. Transcriptomic results suggested that 10-Hydroxy-2-decenoic acid promoted epidermal barrier function and dermal energy metabolism. In vitro experiments revealed that within the epidermal layer, 10-Hydroxy-2-decenoic acid activated <em>PPARα</em> signaling and enhanced the expression of downstream genes <em>IVL</em>, <em>LOR</em>, <em>FLG</em>, and <em>TGM1</em>, thereby promoting epidermal differentiation. It upregulated the expression of <em>SPT</em>, <em>GBA</em>, and <em>ACACA</em>, increasing intercellular lipid content and accelerating the formation of the cornified envelope. In the dermal layer, 10-HDA is capable of enhancing the mitochondrial membrane potential, reinforcing the proton gradient, thereby increasing the efficiency of the coupled electron transport chain and leading to the generation of more ATP. It also upregulates NADPH, providing a certain level of reductive power to reduce the production of oxidative by-products, improving mitochondrial functional efficiency. Taken together, these findings indicated that in addition to its application in food and health products, biologically synthesized 10-Hydroxy-2-decenoic acid could serve as an effective skincare ingredient, contributing to skin barrier repair and resistance against skin aging. However, the deeper mechanism by which 10-HDA functions still needs to be further explored.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106505"},"PeriodicalIF":3.8,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroprotective effects of Olea europaea L. leaf extract on neuroinflammation and memory impairment induced by toluene and noise exposure: Assessing brain changes in rat","authors":"Takoua Ben Attia ,&nbsp;Mabrouk Horchani ,&nbsp;Mariem Salhi ,&nbsp;Ridha Ben Ali ,&nbsp;Hichem Ben Jannet ,&nbsp;Linda Bel Haj Kacem ,&nbsp;Michèle Véronique El May ,&nbsp;Eduardo Alberto López-Maldonado ,&nbsp;Abada Mhamdi","doi":"10.1016/j.jff.2024.106489","DOIUrl":"10.1016/j.jff.2024.106489","url":null,"abstract":"<div><div>Our study aimed to investigate the impact of toluene and/or noise exposure on rat brains and assess the preventive effects of <em>Olea europaea</em> L. leaf extract (OLE) through biochemical, histopathologic analyses, behavior tests, and in silico study. Forty-eight male <em>Wistar</em> rats were randomly divided into eight groups: a control group, an OLE group, a noise-exposed group, a noise-exposed group treated with OLE, a toluene-exposed group, a toluene-exposed group treated with OLE, a co-exposed group to noise and toluene, and a co-exposed group to noise and toluene treated with OLE. OLE was orally administered at 40 mg/kg daily for six weeks. The results showed that noise and toluene exposure significantly disrupted brain tissue structure, causing oxidative damage, as evidenced by increased lipid peroxidation, decreased catalase and superoxide dismutase activities, and increased acetylcholinesterase (AChE) activity. However, OLE administration alleviated oxidative stress by restoring antioxidant biomarker levels, maintaining AChE close to normal, and preserving brain histology, while also improving rat behavior and learning. These findings suggest that OLE may protect brain tissue against simultaneous exposure to noise and toluene. Importantly, these results have significant implications for the prevention and treatment of neurotoxicity associated with exposure to toluene and noise, highlighting the potential practical applications of our research.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106489"},"PeriodicalIF":3.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sophora davidii Hance leaves total alkaloids (SDLTAs) alleviate asthma through inhibiting airway inflammation and regulating TLR4/MyD88/c-Jun pathway based on systematic pharmacology and molecular docking","authors":"Wenbing Zhi ,&nbsp;Xiaoyan Zhang ,&nbsp;Zongren Xu ,&nbsp;Shengnan Jiang ,&nbsp;Shuai Liu ,&nbsp;Jing Chen ,&nbsp;Tingting Sun ,&nbsp;Ye Li ,&nbsp;Xiaofeng Niu ,&nbsp;Yang Liu ,&nbsp;Hong Zhang","doi":"10.1016/j.jff.2024.106472","DOIUrl":"10.1016/j.jff.2024.106472","url":null,"abstract":"<div><div>Asthma is a complex heterogeneous and inflammatory disease with an increasing incidence worldwide. Here, UHPLC-Q-Exactive-MS^E analysis revealed that 21 alkaloids and 1 coumarin compound (Scopoletin) were identified in SDLTAs. In mouse model, SDLTAs treatment reduced the airway pathological damage, the levels of IL-4, IL-5, IgE, MUC5AC, and splenic index. In cell model, SDLTAs treatment significantly decreased IL-6, IL-8, MUC5AC, and mucus secretion induced by LPS. Network pharmacology studies revealed that the main active ingredients of SDLTAs, including oxysophoridine, oxymatrine, scopoletin and sophoridine, target TLR4, DPP4, IL6 and TNF, as well as regulate IL-17 signaling pathway, TNF signaling pathway, and toll-like receptor signaling pathway, leading to relief of asthma on an inflammatory basis. Docking results showed that the binding energy of the main active ingredients of SDLTAs to TLR4 and MyD88 varied from −5.38 kcal/mol to −4.01 kcal/mol. Further, SDLTAs down-regulated the expression of TLR4, MyD88 and p-c-Jun.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106472"},"PeriodicalIF":3.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting suppression of AKT activation boosts chemosensitivity of hepatocarcinoma cells via regulation of inflammation and metastasis: Functional protection of Rehmapicroside","authors":"Xiulei Zhao ,&nbsp;Zhushuang Bai ,&nbsp;Yixiang Song","doi":"10.1016/j.jff.2024.106487","DOIUrl":"10.1016/j.jff.2024.106487","url":null,"abstract":"<div><div>Hepatocellular carcinoma (HCC) is the most common malignant tumors with poor prognosis and few effective therapeutic strategies. Although cisplatin (cDDP) is the first-line chemotherapy for HCC, its application has been limited due to drug resistance and side effects. Rehmapicroside (Reh) is a major active principle of the root of <em>Radix Rehmanniae</em> that has anti-tumor effects. In the present study, we uncovered the role of Reh in modulating chemosensitivity of cDDP in HCC. We found that combinational treatments of Reh and cDDP significantly reduced the cell proliferation of HCC cells at relatively lower concentrations for each drug. Cell cycle arrest in G2/M phase was markedly induced in HCC cells co-treated with Reh and cDDP compared with cDDP alone group. In addition, Reh dramatically enhanced the capacity of cDDP to induce apoptosis in HCC cells through increasing Caspase-3 cleavage. Co-treatment with Reh and cDDP effectively suppressed tumor growth in xenograft mouse models of HCC without adverse effects. Moreover, migration and invasion of HCC cells were significantly restrained by combinational treatments of Reh and cDDP. Mechanistically, tripartite motif protein 21-phosphatidylinositol 3-kinase/protein kinase B (TRIM21-PI3K/AKT) signaling pathway was considerably impeded in HCC cells and tumor tissues by Reh and cDDPco-treatment. Notably, we found that constitutive activation of AKT almost completely abrogated the capacity of Reh plus cDDP to inhibit cell proliferation, migration, and invasion. Collectively, our results demonstrated that combinational therapy of Reh and cDDP may be a novel and effective therapeutic strategy for HCC treatment.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106487"},"PeriodicalIF":3.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the protection on islet β-cells and hypoglycemic effect of Moringa oleifera stem based on network pharmacology and experimental validation","authors":"Xilin Jiang ,&nbsp;Jian Tang ,&nbsp;Zhiqiang Gao ,&nbsp;Caixia Chen ,&nbsp;Wenjun Li ,&nbsp;Lu Peng ,&nbsp;Hongwei Li ,&nbsp;Hongying Zhao ,&nbsp;Yun Zhao","doi":"10.1016/j.jff.2024.106499","DOIUrl":"10.1016/j.jff.2024.106499","url":null,"abstract":"<div><div><em>Moringa oleifera</em> Lam. (<em>M. oleifera</em>) has been used as a remedy for diabetes clinically. To discover the underlying mechanism, we investigated its hypoglycemic compounds and shed light on its regulatory targets and pathways using network pharmacology. A total of 13 active compounds of stem were shot, and they may relieve diabetes through 122 core intersecting targets, mainly regulating the biological processes of inflammatory response and apoptosis. Molecular docking showed binding advantages of the active compounds with proteins in apoptosis process. In experiments conducted on MIN6 cells, an islet β-cell line, the extract of <em>M. oleifera</em> stem was validated to protect cells from apoptosis through reducing cellular ROS and endoplasmic reticulum stress. And consistently with its protective effect on islet β-cells, <em>M. oleifera</em> stem alleviated hyperglycemia in Type 2 diabetes mellitus (T2DM) mice. These results offer novel evidence for the development of functional foods to treat T2DM with <em>M. oleifera</em> stem.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106499"},"PeriodicalIF":3.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Grifola frondosa-derived ACE inhibitory peptide attenuated the exosomes-mediated phenotype transformation of vascular smooth muscle cells","authors":"Tianyuan Song ,&nbsp;Tiantian Zhang ,&nbsp;Qiaolin Cai ,&nbsp;Yin-Yi Ding ,&nbsp;Qing Gu ,&nbsp;Zhenyu Gu","doi":"10.1016/j.jff.2024.106502","DOIUrl":"10.1016/j.jff.2024.106502","url":null,"abstract":"<div><div><em>Grifola frondosa</em>, a high-protein edible mushroom, exhibited potential antihypertensive effects through ACE inhibition. The ACE was expressed in vascular smooth muscle cells (VSMCs) and transported via exosomes. This study prepared low molecular weight GFP through enzymatic hydrolysis, showing strong ACE inhibition. Ang II increased ACE expression and activity in VSMCs, inducing phenotype switching by up-regulating α-SMA and OPN. GFP reduced Ang II’s stimulating effects. Exosomes from Ang II-treated (Ang II-Exos) or GFP-treated (GFP-Exos) VSMCs had particle sizes under 200 nm with positive biomarkers CD63 and Tsg101. Co-culture experiments revealed higher ACE loading in Ang II-Exos than in VSMCs, but significantly lower in GFP-Exos. Ang II-Exos promoted VSMC proliferation, migration, inflammation, and phenotypic switching, while GFP-Exos significantly reduced these effects by inhibiting ACE activity and regulating the NF-κB pathway. GFP effectively mitigated Ang II-induced VSMC dysfunction by modulating exosome-mediated ACE loading and phenotypic transformation.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106502"},"PeriodicalIF":3.8,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of astaxanthin on physical activity factors, lipid profile, inflammatory markers, and antioxidants indices in athletic men: A systematic review and meta-analysis","authors":"Motahareh Hasani ,&nbsp;Zahra Arabpour ,&nbsp;Mahdis Hasani ,&nbsp;Amin Saeedi ,&nbsp;Adeleh Khodabakhshi","doi":"10.1016/j.jff.2024.106477","DOIUrl":"10.1016/j.jff.2024.106477","url":null,"abstract":"<div><div>Studies have shown that oral supplementation with astaxanthin may have a potential role on physical activity-related factors in athletes during exercise training, but the evidence is still inconclusive. Therefore, in this systematic review, we investigate all randomized controlled trials which assessed the effect of astaxanthin on various physical activity factors in athletes. International databases including PubMed, Embase, Scopus, and Web of Science were searched up to 1 June 2024. There was no limitation in the time of publication and language. A random-effects <em>meta</em>-analysis was performed to estimate the pooled effect sizes. Possible sources of heterogeneity were explored by <em>meta</em>-regression analysis. Nine studies were included in our <em>meta</em>-analysis based on our desired outcomes. The results showed that astaxanthin supplementation may improve cycling time trial performance and it can significantly increase total antioxidant capacity (TAC) (SMD: 1.1, 95 % CI: 0.43–1.77, P-value = 0.046). Thus, astaxanthin may improve performance and increase TAC in athletes.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106477"},"PeriodicalIF":3.8,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative investigation of the potential impacts of Pilosocereus gounellei (A. Weber ex K. Schum. Bly. Ex Rowl) cladodes on the human intestinal microbiota","authors":"Sabrina Radames Ferreira da Silva ,&nbsp;Sara de Sousa Rocha ,&nbsp;Jaielison Yandro Pereira da Silva ,&nbsp;Viviane Priscila Barros de Medeiros ,&nbsp;Flávia Figueira Aburjaile ,&nbsp;Rodrigo Dias de Oliveira Carvalho ,&nbsp;Marcelo Sobral da Silva ,&nbsp;Josean Fechine Tavares ,&nbsp;Yuri Mangueira do Nascimento ,&nbsp;Marcos dos Santos Lima ,&nbsp;Cristiane Francisca Costa Sassi ,&nbsp;Mariana Monteiro ,&nbsp;José Luiz de Brito Alves ,&nbsp;Thatyane Mariano Rodrigues de Albuquerque ,&nbsp;Maria Elieidy Gomes de Oliveira ,&nbsp;Evandro Leite de Souza","doi":"10.1016/j.jff.2024.106501","DOIUrl":"10.1016/j.jff.2024.106501","url":null,"abstract":"<div><div><em>Pilosocereus gounellei</em> A. Weber ex K. Schum. Bly. Ex Rowl (xique-xique) is a cactus native to the Brazilian Caatinga biome and considered a non-conventional food plant. This study evaluated the physicochemical characteristics, antioxidant capacity, and impacts on the composition and metabolic activity of human intestinal microbiota of freeze-dried <em>P. gounellei</em> cladodes (FDPg) during 48 h of <em>in vitro</em> colonic fermentation. FDPg had a high nutritional value, the presence of bioactive compounds, and antioxidant capacity. The colonic fermentation of FDPg decreased the <em>Firmicutes/Bacteroidetes</em> ratio and increased bacterial diversity. It also increased the relative abundance of bacterial groups considered beneficial, such as <em>Mitsuokella</em>, <em>Bacteroides</em>, <em>Megasphaera</em>, and <em>Acidaminococcus</em>, and decreased the relative abundance of bacterial groups considered non-beneficial, such as <em>Succinivibrio</em>, <em>Citrobacter</em>, <em>Escherichia-Shigella</em>, <em>Faecalibacterium</em>, and <em>Blautia</em>. The colonic fermentation of FDPg induced the production of various metabolites related to host health promotion. The results show the potential beneficial impacts of FDPg on human intestinal microbiota.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"122 ","pages":"Article 106501"},"PeriodicalIF":3.8,"publicationDate":"2024-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}