{"title":"Basal Crux Ventricular Tachycardia in Ischemic Heart Disease.","authors":"Devendra S Bisht, Kamal Kishor","doi":"10.1016/j.ipej.2025.06.009","DOIUrl":"10.1016/j.ipej.2025.06.009","url":null,"abstract":"<p><strong>Background: </strong>Basal crux ventricular tachycardia (VT) is traditionally considered an idiopathic arrhythmia. However, its occurrence in patients with structural heart disease, especially ischemic heart disease (IHD), is often under recognised.</p><p><strong>Case summary: </strong>We report two patients with a history of myocardial infarction who presented with basal crux VT. In both cases, VT was rendered non-inducible, and both patients experienced recovery of their left ventricular ejection fraction (LVEF), indicating a significant burden of arrhythmia-induced cardiomyopathy.</p><p><strong>Discussion: </strong>It is unclear whether IHD is purely coincidental or contributes to the underlying substrate promoting arrhythmogenesis.</p><p><strong>Conclusion: </strong>Basal crux VT can occur in patients with IHD and may resemble idiopathic epicardial VT. Ablation in the proximal middle cardiac vein (MCV) may be potentially curative.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjeev S Mukherjee, Ashesh Halder, Anil Kumar Singhi, K Sivakumar
{"title":"2: 1 AV block post ASD device closure - What is the mechanism.","authors":"Sanjeev S Mukherjee, Ashesh Halder, Anil Kumar Singhi, K Sivakumar","doi":"10.1016/j.ipej.2025.06.005","DOIUrl":"10.1016/j.ipej.2025.06.005","url":null,"abstract":"<p><p>We report a case of atrioventricular (AV) block post successful percutaneous atrial septal defect (ASD) device closure. He had minimal fatigue and presented for his routine follow-up after intervention. His ECG showed 2:1 AV block. The interesting finding was appearance of varying PR interval in the conducted beats evoking possibility of complete heart block (CHB). We review the literature and conclude that changing PR is part of compensation to maintain R-R interval in a typical Wenckebach phenomenon.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimal strategy for very high-power short-duration atrial fibrillation ablation: Acute efficacy and safety of pulmonary vein and box isolation","authors":"Yusuke Sakamoto, Hiroyuki Osanai, Yoshihito Nakashima, Hiroshi Asano, Masayoshi Ajioka","doi":"10.1016/j.ipej.2025.04.007","DOIUrl":"10.1016/j.ipej.2025.04.007","url":null,"abstract":"<div><h3>Introduction</h3><div>The optimal strategy for very high-power short-duration (vHPSD) ablation for atrial fibrillation (AF) is unclear. Data regarding the application of box isolation (BOXI) and its complications, particularly, pulmonary vein stenosis (PVS), remain scarce. We aimed to determine the optimal strategy for vHPSD in AF ablation by focusing on pulmonary vein isolation (PVI) and BOXI and assessing the acute efficacy and safety.</div></div><div><h3>Methods</h3><div>Patients with drug-refractory AF (n = 97) were divided into two groups: Strategy 1 (n = 50; 90 W for 4 s with PVI for the bottom line and 50 W with an ablation index [AI] of 450 for the roof line) and Strategy 2 (n = 47; based on the outcomes of Strategy 1, using AI-guided ablation). The acute efficacy and safety were compared between the groups. Pre- and post-ablation imaging was conducted to assess PVS.</div></div><div><h3>Results</h3><div>Strategy 1 yielded first-pass isolation (FPI) rates of 62.5 % (PVI) and 72 % (BOXI). The weak points were the thick parts of the atrial wall and the parts with epicardial connections. Strategy 2, which was improved by AI guidance, increased the FPI rates to 97.5 % (PVI) and 95 % (BOXI) and reduced the procedural and fluoroscopy times, respectively. Follow-up imaging showed that the PVS incidence remained low and did not significantly differ between the strategies.</div></div><div><h3>Conclusion</h3><div>AI-guided ablation enhanced the efficacy of vHPSD for PVI and BOXI in Strategy 2. Furthermore, our assessment of PVS demonstrated that vHPSD maintains a favorable safety profile with a low PVS incidence.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 3","pages":"Pages 136-145"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Co-existence of RBM20 and KCNQ1 gene mutations in a patient with long QT syndrome and dilated cardiomyopathy. “Which came first: Chicken or the egg?”","authors":"Jithin S. Panicker, Sam Jacob Chiramel","doi":"10.1016/j.ipej.2025.03.005","DOIUrl":"10.1016/j.ipej.2025.03.005","url":null,"abstract":"<div><div>A 60-year-old female patient was taken to the emergency department with a history of syncope. ECG revealed polymorphic ventricular tachycardia which necessitated recurrent DC cardioversion. Post-reversion ECG showed sinus rhythm with prolonged corrected QTc. Bedside transthoracic echocardiogram revealed features suggestive of dilated cardiomyopathy (DCM) with severe left ventricular dysfunction. Next reversion to VT was managed with intravenous propranolol and DC cardioversion after which she remained in sinus rhythm. After the initiation of beta-blocker, she developed sinus bradycardia followed by complete heart block.</div><div>The concern we had while managing this case was whether the DCM caused the VT {then why long QTc?} OR was the long QTc causing DCM {due to same gene mutation}. Genetic analysis revealed the simultaneous occurrence of KCNQ1 and RBM20 mutation.</div><div>Regarding the treatment given to our patient, we continued beta-blocker, left bundle branch optimized implantable cardioverter defibrillator {LOT – Dx ICD} was done with atrial sensing, the right ventricular coil as the defibrillator, and left bundle branch area pacing.</div><div>In our patient, any of the two mutations could explain the occurrence of both DCM and long QTc. However genetic analysis revealed the simultaneous presence of both RBM20 and KCNQ1 mutation. To the best of our knowledge, this is the first report in the medical literature on the co-existence of RBM20 and KCNQ1 mutation.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 3","pages":"Pages 171-174"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Pereira Santos , André Alexandre , Maria João Sousa , Severo Torres
{"title":"Contralateral pneumothorax, pneumomediastinum, and pneumopericardium after dual-chamber pacemaker implantation","authors":"Mariana Pereira Santos , André Alexandre , Maria João Sousa , Severo Torres","doi":"10.1016/j.ipej.2025.05.005","DOIUrl":"10.1016/j.ipej.2025.05.005","url":null,"abstract":"<div><div>We present a rare case of a 79-year-old man who developed contralateral pneumothorax, pneumomediastinum, and pneumopericardium following dual-chamber pacemaker implantation for symptomatic second-degree atrioventricular block. The procedure itself was uneventful, with appropriate lead placement and good electrical parameters.</div><div>However, 30 minutes post-procedure, the patient developed right-sided pleuritic chest pain and dyspnea. Imaging revealed a right-sided pneumothorax, pleural effusion, pneumomediastinum, and pneumopericardium. A chest drain was inserted due to the significant pneumothorax volume, leading to symptom resolution. Electrocardiographic changes and inflammatory marker elevation suggested pericarditis, which was successfully treated with ibuprofen and colchicine. The patient was discharged after 13 days and remained stable at a 1-year follow-up.</div><div>The suspected mechanism of injury was atrial lead perforation, although other causes, such as pleural puncture or superior vena cava injury, were considered. Management of such cases varies, with lead revision being unnecessary in this patient due to stable pacing parameters. This case highlights an unusual complication of pacemaker implantation and underscores the importance of prompt diagnosis and individualized management.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 3","pages":"Pages 162-166"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramanathan Velayutham, Anish Bhargav, Raja J. Selvaraj
{"title":"A subtle pre-excitation playing hide and seek","authors":"Ramanathan Velayutham, Anish Bhargav, Raja J. Selvaraj","doi":"10.1016/j.ipej.2025.05.003","DOIUrl":"10.1016/j.ipej.2025.05.003","url":null,"abstract":"<div><div>24 years female presented with recurrent palpitations for one year. Sinus ECG showed preexcitation pattern suggestive of a posteroseptal accessory pathway. During the electrophysiology study, atrioventricular reciprocating tachycardia was induced with an atrial extra stimulus. Successful ablation was done in posteroseptal region. Post ablation, there was subtle preexcitation on alternate beats with mid septal pattern which showed short and fixed HV. Short fixed HV and preexcitation morphology remained the same both during atrial pacing and junctional beats. This case highlights the unusual finding of intermittent conduction in fasciculoventricular pathway.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 3","pages":"Pages 132-135"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiogenetics: Closing the knowledge gap in India","authors":"Priya Chockalingam, Arthur A.M. Wilde","doi":"10.1016/j.ipej.2025.05.006","DOIUrl":"10.1016/j.ipej.2025.05.006","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 3","pages":"Pages 175-176"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}