{"title":"Atrial leadless pacemaker implant using Aveir VR in an adolescent with congenital heart disease","authors":"Daniel Cortez","doi":"10.1016/j.ipej.2024.10.004","DOIUrl":"10.1016/j.ipej.2024.10.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Pediatric patients with congenital heart disease repair may develop sinus node dysfunction. Leadless pacemakers have provided an alternative option to transvenous and epicardial device implants for pediatric patients in need of ventricular pacing. We describe the first adolescent patient to receive a leadless pacemaker in the atrium due to symptomatic sinus pauses.</div></div><div><h3>Methods</h3><div>The study was approved by the internal review board of the University of California at Davis. Femoral vein implant was performed of an Aveir VR due to the higher impedance and larger battery capacity.</div></div><div><h3>Results</h3><div>The 16-year-old male with dextro-transposition of the great arteries and ventricular septal defect repair had an uncomplicated atrial appendage implant of an Atrial Aveir VR, under transesophageal echocardiographic guidance. Three-month follow-up demonstrated stable threshold of 0.5 V @ 0.2 milliseconds, impedance of 720 Ω and sensing of 9.1 mV, with 10 % pacing and predicted battery longevity of 22.8 years.</div></div><div><h3>Conclusion</h3><div>Atrial implant of a leadless pacemaker is possible in the older pediatric population without complications, including of the Aveir VR.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 1","pages":"Pages 28-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IPEJ, a reflection of the IHRS. Speaking out my mind …","authors":"","doi":"10.1016/j.ipej.2025.02.001","DOIUrl":"10.1016/j.ipej.2025.02.001","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 1","pages":"Page 1"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrievable dual-chamber leadless pacemaker implant (Aveir DR) in an adult patient with congenital heart disease","authors":"Howard How-Peng Liu, Daniel Cortez","doi":"10.1016/j.ipej.2024.09.001","DOIUrl":"10.1016/j.ipej.2024.09.001","url":null,"abstract":"<div><div>Leadless pacemakers have demonstrated potential as a transvenous pacing option in Adult Congenital Heart Disease patients. Aveir™ single-chamber (VR) leadless pacemakers have demonstrated safety in patients without congenital heart disease in a dual chamber approach. We present a case of dual-chamber pacing using the Aveir dual-chamber (DR) leadless pacemaker in a patient with repaired dextro-transposition of the great arteries with ventricular septal defect (VSD) surgical closure.</div><div>A 26-year-old male patient with a history of transposition of the great arteries status post arterial switch and VSD repair neonatally had complicated second degree atrioventricular block and sinus node dysfunction necessitating pacemaker placement. Epicardial single-chamber ventricular pacemaker was placed neonatally, which was switched to dual-chamber pacemaker at age 17 due to malfunction. Recent fracture of pacemaker leads led to implantation of new dual chamber leadless pacemaker.</div><div>Removal of previous pacemaker leads via mechanical extraction occurred and implantation of Aveir DR leadless pacemaker was performed under anesthesia via right femoral vein access without complication. Follow-up demonstrated Aveir VR threshold of [email protected] ms, R-wave of 8.9mV, impedance of 490Ω, and the Aveir AR threshold of [email protected] ms, P-wave of 3.7mV, and impedance of 400Ω.</div><div>This case demonstrates safety and efficacy of dual chamber leadless pacemaker implantation in an ACHD patient.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 347-350"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Arthur Hansel Diniz da Costa , Gabriela Menichelli Medeiros Coelho, Rhanniel Theodorus Helhyas Oliveira Shilva Gomes Villar, Enia Lúcia Coutinho, Claudio Cirenza, Angelo Amato Vincenzo de Paola
{"title":"Twelve-lead ambulatory ECG recording using a seven-electrode recorder: An alternative method for electrophysiological evaluation","authors":"Carlos Arthur Hansel Diniz da Costa , Gabriela Menichelli Medeiros Coelho, Rhanniel Theodorus Helhyas Oliveira Shilva Gomes Villar, Enia Lúcia Coutinho, Claudio Cirenza, Angelo Amato Vincenzo de Paola","doi":"10.1016/j.ipej.2024.10.005","DOIUrl":"10.1016/j.ipej.2024.10.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Conventional three-lead ambulatory electrocardiogram recording (3L-AECG) is used for the quantitative diagnosis of arrhythmias. However, the lack of crucial information, such as QRS morphology and orientation, renders the 3L-AECG incomplete for planning electrophysiological interventions. The 12-lead AECG (12L-AECG) merges the temporal resolution 3L-AECG with the spatial resolution of the standard electrocardiogram (S-ECG). Although it provides more detail, it is not widely used. This study aimed to verify whether the seven-electrode 12L-AECG and S-ECG have similar waveforms.</div></div><div><h3>Methods</h3><div>A questionnaire consisting of 240 side-by-side comparisons (12 leads from 20 patients) was created. These consisted of a QRS registered using the 12L-AECG and a QRS from the same patient, registered using the S-ECG. The questionnaire was submitted to cardiologists trained in electrophysiology. For each comparison, the evaluator assigned “similar” or “different” depending on their own judgment.</div></div><div><h3>Results</h3><div>Five cardiologists completed the questionnaire, resulting in 1200 answers. The AECG-12 was similar to the ECG in 84.50 % of the instances (95 % confidence interval [CI] 83.20–86.50). The interobserver agreement was moderate (0.542, p < 0.001). The similarity between specific leads ranged up to 98 % (95 % CI 92.96–99.76). No significant differences were found among patients (p = 0.407).</div></div><div><h3>Conclusion</h3><div>The seven-electrode 12L-AECG and S-ECG produced comparable waveforms. This similarity supports the use of 12L-AECG for accurate arrhythmia tracking and assists in planning electrophysiological procedures.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 309-314"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visualization of residual gaps after linear ablation using the LUMIPOINTTM module: A case report","authors":"Yasuyuki Egami, Yasuharu Matsunaga-Lee, Masamichi Yano, Masami Nishino","doi":"10.1016/j.ipej.2024.09.006","DOIUrl":"10.1016/j.ipej.2024.09.006","url":null,"abstract":"<div><h3>Background</h3><div>Macroreentrant atrial tachycardia (ATs) through epicardial conduction is depicted as a focal AT on 3-D mapping, i.e., pseudo-focal AT. A new feature of the Rhythmia mapping system (Boston Scientific), the \"LUMIPOINT module\", can highlight all electrocardiograms (EGMs) above a threshold determined by an adjustable confidence slider (CS). Lowering the CS (L-CS) may highlight undetected electrograms (EGMs) at the nominal CS setting, potentially enabling visualization of the critical isthmus of pseudo-focal ATs.</div></div><div><h3>Methods and results</h3><div>This study included 3 ATs after linear ablation of two left atrial roof-dependent ATs (cases 1 and 2) and one peri-mitral flutter (case 3). All ATs were diagnosed as pseudo-focal AT according to an electrophysiological study and the Rhythmia mapping system with the LUMIPOINT module. The L-CS method consisted of the following steps: 1. Set the LUMIPOINT activation window to the time difference before and after the linear ablation line. 2. Highlight the two regions before and after the linear ablation line. 3. Gradually lower the CS value from the nominal setting of 85 % by 5–10 %. By the L-CS method in cases 1–3, the 2-sided highlighted areas before and after the prior linear ablation lesion gradually expanded and eventually fused. EGMs at the fusion sites of the highlighted areas exhibited fragmented EGMs with a low voltage, where a single-shot ablation terminated the targeted ATs.</div></div><div><h3>Conclusion</h3><div>The L-CS method was useful for the visualization of residual gaps and identification of targeted ablation sites in cases of pseudo-focal AT after linear ablation of macroreentrant ATs.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 361-365"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Premature ventricular contraction arising from the left coronary sinus cusp: Which signal is the target of ablation?","authors":"Takashi Nakashima , Masaru Nagase , Shigekiyo Takahashi , Takuma Aoyama","doi":"10.1016/j.ipej.2024.09.003","DOIUrl":"10.1016/j.ipej.2024.09.003","url":null,"abstract":"<div><div>We described a premature ventricular contraction arising from the left coronary sinus cusp, in which we discussed about the interpretations of the signals recorded there. Our case provided further insights into the interpretation of signals recorded at the coronary sinus cusp during premature ventricular contraction ablation.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 355-357"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rabbia Siddiqi , Anas Fares , Mona Mahmoud , Kanwal Asghar , Ragheb Assaly , Ehab Eltahawy , Blair Grubb , George V. Moukarbel
{"title":"Comparison of rhythm versus rate control of atrial fibrillation in heart failure subgroups: Systematic review and meta-analysis of randomized controlled trials","authors":"Rabbia Siddiqi , Anas Fares , Mona Mahmoud , Kanwal Asghar , Ragheb Assaly , Ehab Eltahawy , Blair Grubb , George V. Moukarbel","doi":"10.1016/j.ipej.2024.09.004","DOIUrl":"10.1016/j.ipej.2024.09.004","url":null,"abstract":"<div><div>Patients with concurrent heart failure (HF) and atrial fibrillation (AF) have poor outcomes. Randomized clinical trials comparing rhythm control approaches to rate control of AF have yielded conflicting results and there is a paucity of updated and comprehensive evidence summaries to inform best practice in HF patients. We therefore conducted a systematic review and meta-analysis to compare outcomes with rhythm versus rate control of AF in various subgroups of HF patients. In HF patients overall, we found high certainty evidence that rhythm control decreased all-cause and cardiovascular mortality (hazard ratio [HR, 95 % confidence interval] 0.64 [0.43–0.94]) and HR 0.50 [0.34–0.74] respectively). Rhythm control was associated with decreased HF hospitalization (risk ratio [RR] 0.79 [0.63–0.99], moderate certainty), but did not significantly decrease thromboembolic events (RR 0.67 [0.32–1.39], low certainty). The mean difference in left ventricular ejection fraction [LVEF] from baseline to last follow-up was greater in rhythm control group by 6.01 % [2.73–9.28 %] compared with rate control. Subgroup analyses by age, HF etiology (ischemic or non-ischemic), LVEF, presence of diabetes and hypertension did not reveal any significant differences in treatment effect. The survival and hospitalization reduction benefit of rhythm control of AF in HF patients likely reflects the success of catheter ablation especially in HF with reduced ejection fraction. These data are important to guide shared decision-making when managing AF in HF patients.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 321-329"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benedikt Seither , Alexander Schober , Raphael Allgaier , Christine Meindl , Michael Paulus , Ute Hubauer , Andreas Schober , Ekrem Ücer , Sabine Fredersdorf , Petra Lehn , Andreas Keyser , Andreas Luchner , Lars Maier , Stefan Wallner , Carsten Jungbauer
{"title":"Urinary NT-proBNP compared head-to-head to plasmatic NT-proBNP in a real life collective with an ICD","authors":"Benedikt Seither , Alexander Schober , Raphael Allgaier , Christine Meindl , Michael Paulus , Ute Hubauer , Andreas Schober , Ekrem Ücer , Sabine Fredersdorf , Petra Lehn , Andreas Keyser , Andreas Luchner , Lars Maier , Stefan Wallner , Carsten Jungbauer","doi":"10.1016/j.ipej.2024.10.006","DOIUrl":"10.1016/j.ipej.2024.10.006","url":null,"abstract":"<div><h3>Aims</h3><div>Plasma NT-proBNP is an established marker of heart failure. Previous studies suggested urinary NT-proBNP has potential as marker of chronic heart failure as well. The objective of this study was to compare urinary NT-proBNP to plasma NT-proBNP in a real-life collective of patients with an ICD, especially regarding ICD-therapies.</div></div><div><h3>Methods & results</h3><div>NT-proBNP was assessed in plasma and fresh spot urine (the latter related to urinary creatinine) from 322 patients of our ICD outpatient clinic. 54 healthy individuals served as a control group. Follow-up regarding mortality and ICD therapies was performed after 32 months (IQR 5–35 months). Plasma and urinary NT-proBNP was positively correlated (r = 0.89, p < 0,001). According to ROC analysis urinary NT-proBNP detected LV dysfunction (EF<35 % vs. healthy CTRL) with very satisfying predictive values (AUC 0.95), but plasma NT-proBNP showed slightly better values (AUC 0.99). Patients who received appropriate ICD-shock-therapies showed significantly higher plasma (p < 0.001) as well as urinary NT-proBNP levels (p = 0.011) compared to patients without shock-therapy. In Kaplan-Meier analysis, plasma as well as urinary NT-proBNP levels > Youden-Index showed significantly higher event rates for appropriate ICD-shock therapies (p < 0.001 and p = 0.016) and the combined endpoint of all-cause-mortality and shock therapies (each p < 0.001). Urinary and plasma NT-proBNP were independent predictors for appropriate ICD-shock-therapies and for the combined endpoint of all-cause mortality and appropriate ICD-shock-therapies (each p < 0.001).</div></div><div><h3>Conclusion</h3><div>Urinary NT-proBNP as a marker for LV dysfunction and symptomatic heart failure showed promising predictive values. Associations between plasma as well as urinary NT-proBNP and ICD shock-therapies could be shown.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 315-320"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Janus Heads of ventricular Tachycardia: Single-circuit with dual exits","authors":"Devendra S. Bisht, Kamal Kishor","doi":"10.1016/j.ipej.2024.08.005","DOIUrl":"10.1016/j.ipej.2024.08.005","url":null,"abstract":"<div><div>In the setting of ischemic heart disease (IHD), ventricular tachycardia (VT) commonly originates from areas of incomplete scar tissue. High-density electroanatomic mapping has enhanced our understanding of VT circuits, predominantly characterised by dense scar and surviving myocyte bundles. We present a case of a 58-year-old male with IHD and sustained monomorphic VT, successfully treated with radiofrequency ablation following high-density mapping and entrainment techniques. Two inducible VT phenotypes were identified, with ablation at one site effectively terminating both VT morphologies. This case illustrates the importance of precise circuit localisation and targeted ablation in managing post-infarction VT, leading to a satisfactory patient outcome.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 337-346"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergei Viktorovich Nemtsov , Roman Borisovich Tatarskiy , Sergei Arturovich Termosesov , Dmitriy Sergeevich Lebedev
{"title":"A case report of a combined implantation technique of a cardioverter-defibrillator in an infant with long QT syndrome type 8 (Timothy's syndrome)","authors":"Sergei Viktorovich Nemtsov , Roman Borisovich Tatarskiy , Sergei Arturovich Termosesov , Dmitriy Sergeevich Lebedev","doi":"10.1016/j.ipej.2024.09.002","DOIUrl":"10.1016/j.ipej.2024.09.002","url":null,"abstract":"<div><div>We present a case of successful implantation of a cardioverter-defibrillator (ICD) using combined technique in a child with Timothy's syndrome. Due to high risk of sudden cardiac death (SCD) such patients often need ICD for primary or secondary prevention but implantation technique in young children remains controversial. The subcutaneous cardioverter-defibrillators could be an option in some cases, however, reliable cardiac pacing should be implemented for patients with bradyarrhythmias. An ICD implantation technique with the epicardial pacing lead placement and subcutaneous tunnel formation for endocardial defibrillation lead seems to be promising in SCD prevention also providing the opportunity for permanent pacing.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"24 6","pages":"Pages 351-354"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}