Indian Pacing and Electrophysiology Journal最新文献

{"title":"Combination of cardiac MRI with conventional 3D-EAM to guide catheter ablation of ventricular arrhythmias in structural heart disease: A meta-analysis","authors":"Watsapon Chuanchai ,&nbsp;Patavee Pajareya ,&nbsp;Somkiat Phutinart ,&nbsp;Janista Kaewsrihawong ,&nbsp;Nuttawut Visaltanachoti ,&nbsp;Noppachai Siranart ,&nbsp;Jackson J. Liang ,&nbsp;Nithi Tokavanich ,&nbsp;Ronpichai Chokesuwattanaskul","doi":"10.1016/j.ipej.2026.02.006","DOIUrl":"10.1016/j.ipej.2026.02.006","url":null,"abstract":"<div><h3>Background</h3><div>Use of 3-dimensional electroanatomic mapping (3D-EAM) has become a standard when ablating ventricular arrhythmias (VA) in patients with structural heart disease (SHD). Integrating cardiac magnetic resonance imaging (CMR) with 3D-EAM might improve substrate detection and ablation outcomes. Our study aims to evaluate the outcomes of integrating CMR with 3D-EAM for VA ablation in patients with SHD.</div></div><div><h3>Methods</h3><div>A literature search was conducted up to December 2025, focusing on the integration of CMR into ablation procedures in patients with VA and SHD. CMR studies were categorized into <em>CMR-guided</em> (CMR data were merged with 3D-EAM) and <em>CMR-</em>aided (CMR data were used to assist in mapping or procedural approach). The control group was patients who received 3D-EAM alone. Primary endpoint was VA recurrence. Secondary endpoints were procedural success, procedural time, fluoroscopy time, radiofrequency ablation (RF) time, and major procedural-related complications.</div></div><div><h3>Results</h3><div>A total of 18 studies were included (1,243 participants, mean age 62.7 ± 12.5 years). Both the CMR-guided and CMR-aided had a VA recurrence of 25% and 26%, compared to 51% in 3D-EAM. The CMR-guided showed significantly lower VA recurrence (OR 0.26, 95% CI: 0.17–0.39, I² = 0%, τ² = 0) and higher procedural success (OR 2.27, 95% CI 1.16-4.41, I² = 0%, τ² = 0) compared to 3D-EAM. Major procedural-related complications were low across all groups with 3%, 4%, and 2% in CMR-guided, CMR-aided, and 3D-EAM, respectively. There were no differences in procedural time, fluoroscopy time, and RF time.</div></div><div><h3>Conclusion</h3><div>The CMR-guided ablation approach in patients with VA and SHD demonstrated a lower VA recurrence and higher procedural success with comparable safety to 3D-EAM alone.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 123-132"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146182813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pacemaker pocket histoplasmosis – A rarest of rare CIED infection","authors":"Mohd Iqbal Dar ,&nbsp;Sheikh Mohamad Tahir ,&nbsp;Zafirah Zahir ,&nbsp;Ajaz A. Lone","doi":"10.1016/j.ipej.2026.01.012","DOIUrl":"10.1016/j.ipej.2026.01.012","url":null,"abstract":"<div><div>Cardiac Implantable Electronic Device infections continue to pose a pivotal threat to the successful management of various cardiac electrical disturbances. We present a case of a 79-year-old male who had undergone a dual-chamber pacemaker implantation 10 years ago. Patient presented with a history of fluctuant swelling over the pacemaker pocket, which has been slowly increasing in size over the past 1 year. There were no other signs of infection. Patient was approaching the pacemaker generator replacement indication. The patient underwent complete enucleation of the pacemaker pocket and replacement of the pacemaker generator. On histopathological examination of the specimen, Histoplasma spores were seen within macrophages of the specimen, confirming the diagnosis of histoplasmosis. The patient was further treated with antifungal therapy.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 162-165"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left atrial appendage edema and spontaneous echo contrast following pulsed field ablation for pulmonary vein isolation: A case report","authors":"Jefri Lim ,&nbsp;Beny Hartono ,&nbsp;Evan J. Gunawan ,&nbsp;Dian L. Munawar ,&nbsp;Firman Tedjasukmana ,&nbsp;Muhammad Munawar","doi":"10.1016/j.ipej.2025.10.006","DOIUrl":"10.1016/j.ipej.2025.10.006","url":null,"abstract":"<div><div>Pulsed Field Ablation (PFA) is a novel non-thermal ablation technique with several advantages and fewer complications. A 70-year-old male with persistent atrial fibrillation, heart failure with preserved ejection fraction, and prior ischemic stroke who underwent pulmonary vein isolation using PFA with planned left atrial appendage closure (LAAC). Post-ablation transesophageal echocardiography revealed significant dense spontaneous echo contrast in the left atrial appendage (LAA) and left atrial ridge edema, leading to LAAC postponement and anticoagulation initiation. While PFA has advantages over conventional ablation, its impact on LAA structures requires further study, especially when considering concomitant with LAAC.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 155-158"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in ventricular arrhythmias and sudden cardiac death: A guide for clinicians","authors":"Ibrahim Antoun ,&nbsp;Xin Li ,&nbsp;Ahmed Abdelrazik ,&nbsp;Mahmoud Eldesouky ,&nbsp;Kaung Myat Thu ,&nbsp;Mokhtar Ibrahim ,&nbsp;Harshil Dhutia ,&nbsp;Riyaz Somani ,&nbsp;G. André Ng","doi":"10.1016/j.ipej.2025.09.005","DOIUrl":"10.1016/j.ipej.2025.09.005","url":null,"abstract":"<div><div>Sudden cardiac death (SCD) from ventricular arrhythmias (VAs) remains a leading cause of mortality worldwide. Traditional risk stratification, primarily based on left ventricular ejection fraction (LVEF) and other coarse metrics, often fails to identify a large subset of patients at risk and frequently leads to unnecessary device implantations. Advances in artificial intelligence (AI) offer new strategies to improve both long-term SCD risk prediction and near-term VAs forecasting. In this review, we discuss how AI algorithms applied to the 12-lead electrocardiogram (ECG) can identify subtle risk markers in conditions such as hypertrophic cardiomyopathy (HCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), and coronary artery disease (CAD), often outperforming conventional risk models. We also explore the integration of AI with cardiac imaging, such as scar quantification on cardiac magnetic resonance (CMR) and fibrosis mapping, to enhance the identification of the arrhythmogenic substrate.</div><div>Furthermore, we investigate the application of data from implantable cardioverter-defibrillators (ICDs) and wearable devices to predict ventricular tachycardia (VT) or ventricular fibrillation (VF) events before they occur, thereby advancing care toward real-time prevention. Amid these innovations, we address the medicolegal and ethical implications of AI-driven automated alerts in arrhythmia care, highlighting when clinicians can trust AI predictions. Future directions include multimodal AI fusion to personalize SCD risk assessment, as well as AI-guided VT ablation planning through imaging-based digital heart models. This review provides a comprehensive overview for general medical readers, focusing on peer-reviewed advances globally in the emerging intersection of AI, VAs, and SCD prevention.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 195-203"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing a National Cardiopulmonary Resuscitation Program in Indian High schools and colleges: An expert collaborative call to action and implementation model","authors":"Dhanunjaya Lakkireddy ,&nbsp;Jiaqi Mi ,&nbsp;Aditya Kapoor ,&nbsp;Aashish Katapadi ,&nbsp;Jalaj Garg ,&nbsp;Rakesh Gopinathannair ,&nbsp;Deepak Padmanabhan ,&nbsp;Sana M. Al-Khatib ,&nbsp;Jagmeet P. Singh ,&nbsp;Vanita Arora ,&nbsp;Anil Saxena ,&nbsp;Christina Y. Miyaki ,&nbsp;Eduardo B. Saad ,&nbsp;Suresh Allamshetty ,&nbsp;Anoop Gupta ,&nbsp;Rakesh Yadav ,&nbsp;Suchit Mazumdar ,&nbsp;Nitish Naik ,&nbsp;David S. Frankel ,&nbsp;Ashish Nabar ,&nbsp;Mina K. Chung","doi":"10.1016/j.ipej.2025.11.011","DOIUrl":"10.1016/j.ipej.2025.11.011","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 92-102"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ibutilide: what's clinically proven, what's being investigated?","authors":"Nevin Britto,&nbsp;Mithilesh Das","doi":"10.1016/j.ipej.2026.02.013","DOIUrl":"10.1016/j.ipej.2026.02.013","url":null,"abstract":"<div><div>Ibutilide is a class III antiarrhythmic drug used intravenously for the chemical cardioversion of atrial fibrillation (AF) and atrial flutter (AFL). It mainly acts by blocking the rapid component (I_kr) of delayed rectifier K⁺ channels, resulting in prolongation of action potential duration in the atrium. Ibutilide fumarate is a methanesulfonamide derivative that is structurally similar to sotalol without the β-adrenoreceptor blocking activity. The success rate of cardioversion of atrial flutter with ibutilide is in the range of 50–70%, whereas its efficacy for the conversion of atrial fibrillation is 30–50%. As compared to ibutilide monotherapy, coadministration with propafenone has a significantly higher success rate of AF termination. Ibutilide is also effective in pre-excited AF by reducing the risk of AF related ventricular tachycardia and thereby reducing the risk of sudden cardiac death. It is a safe drug to use for cardioversion in patients on chronic amiodarone therapy. The main side effect of dofetilide is torsade de pointes (tdp), which occurs in 4% patients, and monomorphic ventricular tachycardia, which occurs in 4.9% patients. Proadministration of magnesium reduces the risk of torsade de pointes. Patients should be monitored for at least 4 h for tdp. Targeting complex fractionated electrograms with the assistance of an ibutilide infusion during catheter ablation of persistent AF has shown mixed results. Conversion rate with an ibutilide infusion is only 30% in the presence of an enlarged left atrium (&gt;5 cm) and 37.7% in the presence of mitral valve disease (MVD), whereas the conversion rate was 82.5% in the absence of MVD and 85% in the absence of both an enlarged left atrium and mitral valve disease (p = &lt;0.001). Ibutilide can be used effectively in patients who are not a candidate for direct current cardioversion or who chose not to undergo electric cardioversion.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 179-183"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"9Th World Congress of Pediatric Cardiology and Pediatric Cardiac Surgery (Hongkong) – Highlights","authors":"Sabrina Tsao,&nbsp;Julia Shi","doi":"10.1016/j.ipej.2026.02.010","DOIUrl":"10.1016/j.ipej.2026.02.010","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 89-91"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Signature ECG part 6: Palpitations in a young male with a positive family history for Sudden cardiac death","authors":"Arthur AM. Wilde,&nbsp;Priya Chockalingam","doi":"10.1016/j.ipej.2026.02.012","DOIUrl":"10.1016/j.ipej.2026.02.012","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"26 2","pages":"Pages 177-178"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regular wide complex tachycardia: Sheep in Wolf's clothing.","authors":"Sampath Kumar Madapati, Krishna Prasad Akkineni, Enosh Katta, Mohan Prasad Akkineni","doi":"10.1016/j.ipej.2026.02.015","DOIUrl":"10.1016/j.ipej.2026.02.015","url":null,"abstract":"<p><p>A young male presented with palpitations and wide complex tachycardia with a rate of 250/min. The differential diagnoses of wide complex tachycardia are discussed and the limitations of current diagnostic algorithms are highlighted.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147345432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Irregularly irregular AVNRT misdiagnosed by smartwatch.","authors":"Yaanik B Desai, Nitish Badhwar","doi":"10.1016/j.ipej.2026.02.007","DOIUrl":"10.1016/j.ipej.2026.02.007","url":null,"abstract":"<p><p>A fifty-one-year-old woman presented with an irregularly irregular rhythm noted on a smartwatch. EP study revealed a narrow complex A-on-V tachycardia with significant cycle-length variability. Pacing maneuvers were consistent with atrioventricular nodal re-entry tachycardia (AVNRT), and we performed slow pathway modification. While AVNRT can have some degree of variability - particularly on warm up - the amount of irregularity here was striking, and much more than we have ever encountered or than has been previously reported in the literature.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}