Shubash Adhikari , Shabnam Tiwari , Jonathan Shakesprere , Suzanne Kemper , Elaine Davis , William Carter
{"title":"Predictors and timeline of spontaneous conversion to normal sinus rhythm: A single center retrospective cohort study of patients with symptomatic atrial fibrillation","authors":"Shubash Adhikari , Shabnam Tiwari , Jonathan Shakesprere , Suzanne Kemper , Elaine Davis , William Carter","doi":"10.1016/j.ipej.2023.09.002","DOIUrl":"10.1016/j.ipej.2023.09.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Annual healthcare expenditures associated with atrial fibrillation (AF) in the United States (US) continue to grow as more symptomatic patients present to emergency departments (ED). Predictors of spontaneous conversion to normal sinus rhythm (ScNSR) remain poorly understood, as well as the timeline of ScNSR remains unclear. We sought to 1) to assess the association of key demographics, anthropometric, and clinical factors to ScNSR and 2) to evaluate the timeline of ScNSR, and 3) determine clinical predictors of ScNSR.</p></div><div><h3>Methods</h3><p>This single center, retrospective cohort study analyzed patients aged ≥18 years with symptomatic AF as diagnosed and evaluated through the ED of a rural tertiary care center in West Virginia from September 2015 to December 2018.</p></div><div><h3>Results</h3><p>Our cohort consisted of 375 AF patients (mean age 65 years, 54% male). A total of 177 patients attained ScNSR either in the ED or after hospital admission with a mean conversion time of 14.7 h (±12). Onset of symptoms <24 hrs has strong positive association to ScNSR 3.97 (95% CI: 2.24–7.05; p < 0.0001). Male gender 0.55 (95% CI: 0.35–0.85; p = 0.007) and hypertension 0.48 (95% CI: 0.31–0.76; p = 0.002), showed a strong negative association to ScNSR. Of the patients that converted spontaneously (177), the majority, 136 (76.8%) achieved ScNSR within 24 h of ED triage without use of electrical or chemical cardioversion.</p></div><div><h3>Conclusion</h3><p>Most patients with AF in the ED converted spontaneously to sinus rhythm within the first 24 h which underscores the importance of earlier watchful waiting over interventions to achieve normal sinus rhythm (NSR).</p></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0972629223000967/pdfft?md5=8bc36f4746e770c0a2fb35c053c27a6f&pid=1-s2.0-S0972629223000967-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41153257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pacing for atrioventricular block with preserved left ventricular function: On-treatment comparison between his bundle, left bundle branch, and right ventricular pacing","authors":"Shunmuga Sundaram Ponnusamy , Pugazhendhi Vijayaraman","doi":"10.1016/j.ipej.2023.09.006","DOIUrl":"10.1016/j.ipej.2023.09.006","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0972629223001006/pdfft?md5=a264aa6db2976d72f17503e73fd21906&pid=1-s2.0-S0972629223001006-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41168603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Electrocardiographic lead reversals","authors":"Amal Paul , John Roshan Jacob","doi":"10.1016/j.ipej.2023.09.005","DOIUrl":"10.1016/j.ipej.2023.09.005","url":null,"abstract":"<div><p>Misplacement of cables during the recording of a 12-lead electrocardiogram [ECG] poses a non-negligible risk of creating panic and confusion at the bedside in daily clinical practice. Clinical awareness about the manifestations of commonly encountered electrode misplacements is imperative for avoiding misdiagnosis. A basic understanding of the electrophysiology behind these anomalous ECG tracings is likely to aid in prompt suspicion, accurate detection, and appropriate rectification in most cases. We discuss the abnormalities produced on 12-lead ECG tracings by the misplacement of electrode cables, with a focus on the clinical implications of the same. We suggest a mnemonic - ‘SPIRAL’ - as a quick screening criterion to detect commonly encountered lead reversals.</p></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0972629223000992/pdfft?md5=501aa349f4ba10f8f244ed5158b6ece9&pid=1-s2.0-S0972629223000992-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41180152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conduction system pacing embarking on a journey of preventive medicine","authors":"Ulhas M. Pandurangi","doi":"10.1016/j.ipej.2023.10.005","DOIUrl":"10.1016/j.ipej.2023.10.005","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0972629223001055/pdfft?md5=257c901e54d84baf9068067cafd25429&pid=1-s2.0-S0972629223001055-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arrhythmic and mortality outcomes in patients with dilated cardiomyopathy receiving cardiac resynchronization therapy without defibrillator","authors":"Mohammed Samy , Rehab M. Hamdy","doi":"10.1016/j.ipej.2023.08.002","DOIUrl":"10.1016/j.ipej.2023.08.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The routine implantation of cardiac resynchronization therapy with defibrillators in all patients who are candidates for this treatment is now being negotiated, mainly in patients with dilated cardiomyopathy<strong>.</strong></p></div><div><h3>Objective</h3><p>We investigated the arrhythmic and mortality outcomes following CRT implantation in DCM, as well as the necessity for defibrillator capabilities in that particular group of patients.</p></div><div><h3>Methods</h3><p>we included 67- patients with DCM with EF ≤ 35%, QRS duration >130 msec and NYHA class II-IV, or those with EF ≤ 35% with indications of permanent pacing for implantation of CRT-P. Patients were followed to obtain good CRT response. Improved clinical outcomes were defined as improvement in at least one NYHA class, ≥5% increase in LVEF, and ≥15% reduction in left ventricular end-systolic volume versus baseline. Patients were classified into responder and non-responder. Patients were followed for 36 months regarding all-cause morbidity mainly ventricular tachycardia and all-cause mortality.</p></div><div><h3>Results</h3><p>CRT responder patients had better clinical outcomes than CRT non-responder patients (post NYHA, 1.3 ± 0.5 vs. 2.5 ± 0.6, p < 0.0001; post LVEF 30.0 ± 1.6 vs. 20.3 ± 2.2%, p < 0.0001; LVESV, 151.7 ± 7.6 vs. 190.4 ± 9.0 ml, p < 0.0001), with lower ventricular arrhythmia (p < 0.0001), lower mortality (p = 0.015) and lower all-cause morbidity (p < 0.001). This survival advantage may be related to the response to CRT response determined by clinical and echocardiographic parameters over a 36-month period of follow-up.</p></div><div><h3>Conclusions</h3><p>Our findings suggest that CRT-P implantation without defibrillation backup is an encouraging treatment option for patients with DCM, principally those who responded to it. It may result in cost savings, a decrease in complications, and an improvement in all-cause morbidity, particularly ventricular arrhythmia and survival.</p></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0972629223000785/pdfft?md5=26c1f1de2f57971e6c7f4f50d829f1ee&pid=1-s2.0-S0972629223000785-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10002949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resynchronization for shifting conduction patterns - When a coronary sinus lead is not enough","authors":"Karol Curila , Pavel Jurak , Niraj Varma","doi":"10.1016/j.ipej.2023.08.005","DOIUrl":"10.1016/j.ipej.2023.08.005","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0972629223000931/pdfft?md5=20159e193f9bb271dd8bc1b8a2e70443&pid=1-s2.0-S0972629223000931-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10481288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Premature atrial contraction induced cardiomyopathy: A case report","authors":"Devendra Singh Bisht","doi":"10.1016/j.ipej.2023.10.002","DOIUrl":"10.1016/j.ipej.2023.10.002","url":null,"abstract":"<div><p>This case report describes the successful management of a 45-year-old female patient with incessant premature atrial complexes (PACs) leading to left ventricular dysfunction. Despite initial treatment with beta-blockers, the patient's PACs persisted, prompting catheter ablation. Mapping in the left atrium identified the site of earliest atrial activation near the right superior pulmonary vein, and radiofrequency energy successfully terminated the PACs. Follow-up assessments showed the patient remained asymptomatic, with normalized left ventricular function. This case highlights the efficacy of catheter ablation in resolving PAC-induced cardiomyopathy and emphasizes the need for further research in this area.</p></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S097262922300102X/pdfft?md5=def4dd28938e6e64700d270490bde6d1&pid=1-s2.0-S097262922300102X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41172058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intra-septal radiofrequency ablation within the transseptal puncture hole targeting an interatrial connection during a bi-atrial tachycardia","authors":"Takehito Sasaki , Kohki Nakamura , Kentaro Minami , Shigeto Naito","doi":"10.1016/j.ipej.2023.08.001","DOIUrl":"10.1016/j.ipej.2023.08.001","url":null,"abstract":"<div><p>A 74-year-old man after multiple mitral valve surgeries underwent catheter ablation of a bi-atrial tachycardia (BiAT). Ultra-high resolution activation mapping exhibited a reentrant circuit propagating around the inferior to anterior mitral annulus and right atrial (RA) septum with two interatrial connections. At the transeptal puncture site, continuous fractionated electrograms were recorded during the BiAT, and entrainment pacing revealed a post-pacing interval similar to the tachycardia cycle length, which suggested that the interatrial conduction from the RA to the left atrium (LA) was located just at the transseptal puncture site. A radiofrequency application inside the transseptal puncture hole could successfully eliminate the BiAT. The ablation target for BiATs propagating around the mitral annulus and RA septum is generally the anatomical mitral isthmus (MI). Since the present case had multiple incisions on both the RA and LA septum due to mitral valve surgeries, there was the possibility of the occurrence of a BiAT including the RA and LA septum after performing an MI linear ablation. Therefore, the preferable ablation target for the BiAT in the present case appeared to be the interatrial connection. Ultra-high resolution detailed mapping not only on the atrial endocardium but also in the transseptal puncture hole may be useful for identifying a critical interatrial connection of BiAT circuits.</p></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/39/main.PMC10491961.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10263641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left ventricular septal pacing – can we trust the ECG?","authors":"Karol Curila , Haran Burri","doi":"10.1016/j.ipej.2023.07.001","DOIUrl":"10.1016/j.ipej.2023.07.001","url":null,"abstract":"<div><p>In contrast to left bundle branch pacing, the criteria for left ventricular septal pacing (LVSP) were never validated. LVSP is usually defined as deep septal deployment of the pacing lead with a pseudo-right bundle branch morphology in V1. The case report describes an implant procedure during which this definition of LVSP was fulfilled in four of five pacing locations within the septum, with the shallowest of them present in less than 50% of the septal thickness. The case highlights the need for a more precise definition of LVSP.</p></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/ec/main.PMC10491966.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10558833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}