Indian Pacing and Electrophysiology Journal最新文献

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Reversible cardiomyopathy due to ventricular arrhythmias in a |highly unusual syndrome. A novel phenotypical presentation. 由室性心律失常引起的可逆性心肌病在b|非常罕见的综合征。一种新的表型表现。
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-27 DOI: 10.1016/j.ipej.2026.10.012
Oscar A Pellizzón, Sebastián Nannini, Lucía I Vago, Fabio Blassi
{"title":"Reversible cardiomyopathy due to ventricular arrhythmias in a |highly unusual syndrome. A novel phenotypical presentation.","authors":"Oscar A Pellizzón, Sebastián Nannini, Lucía I Vago, Fabio Blassi","doi":"10.1016/j.ipej.2026.10.012","DOIUrl":"https://doi.org/10.1016/j.ipej.2026.10.012","url":null,"abstract":"<p><p>We present a 16-year-old female with multisystemic disorder characterized by cutaneous hyperpigmentation, hypertrichosis, hepatosplenomegaly, hearing loss, heart anomalies, hypogonadism, low height (short stature), hyperglycemia and hallux valgus and pathogenic variant in SLC29A3 gene (encoding the human equilibrate nucleoside transporter (hENT3), was referred for evaluation due to recurrent non-sustained pleomorphic ventricular tachycardia refractory to amiodarone and catheter ablation. Two-dimensional echocardiography and cardiac magnetic resonance with late-gadolinium enhancement showed reduced biventricular ejection fraction without signs of inflammation or fibrosis. The administration of propranolol and flecainide controlled her ventricular arrhythmias and improved ventricular function. To our knowledge, this the first time that this arrhythmic phenotype has been demonstrated in this unusual syndrome presenting probably as a cardiomyopathy secondary to recurrent non-sustained pleomorphic ventricular tachycardia that was reversed with administration of flecainide and propranolol.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149289044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LEFT BUNDLE BRANCH AREA PACING IN A POST TRANSPLANT HEART WITH MILD LV DYSFUNCTION- A CASE REPORT. 移植后心脏左束支区起搏伴轻度左室功能障碍1例。
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-27 DOI: 10.1016/j.ipej.2026.10.013
Athira Thomas, Arun Gopi, P P Muhammed Musthafa, Shunmuga Sundaram
{"title":"LEFT BUNDLE BRANCH AREA PACING IN A POST TRANSPLANT HEART WITH MILD LV DYSFUNCTION- A CASE REPORT.","authors":"Athira Thomas, Arun Gopi, P P Muhammed Musthafa, Shunmuga Sundaram","doi":"10.1016/j.ipej.2026.10.013","DOIUrl":"https://doi.org/10.1016/j.ipej.2026.10.013","url":null,"abstract":"<p><p>Left bundle branch pacing (LBBP) is increasingly used as a physiological alternative to right ventricular pacing, with stable thresholds and synchronized left ventricular activation. Its use in a transplanted heart is rarely described, and data on conduction system pacing in this setting is limited. We describe a 38-year-old woman who developed complete atrioventricular dissociation with a wide, LBBB-morphology escape rhythm immediately after orthotopic cardiac transplantation performed for peripartum cardiomyopathy with biventricular dysfunction. Baseline echocardiography showed global LV hypokinesia with an ejection fraction of 45%. Given high-grade AV block with LV dysfunction, we implanted a left bundle branch optimized dual-chamber pacemaker. The paced QRS showed a right bundle branch delay pattern with left axis deviation, in keeping with left posterior fascicular capture, and thresholds remained low and stable at follow-up. The patient has done well since, with a ventricular pacing burden of 100%, no device-related complications, and recovery of LV ejection fraction from 45% to 60% on serial echocardiography. As far as we are aware, this is the first reported instance of left bundle branch pacing in a post-transplant heart. The case suggests that LBBP is feasible in the transplanted heart and may support recovery of LV function even when the heart is denervated, though longer follow-up and further cases will be needed to confirm this. Written informed consent was obtained from the patient for publication of this report and the accompanying images.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149289079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing an Institutional Paediatric EP Practice in Hong Kong: our reflections. 在香港发展机构儿科EP实践:我们的反思。
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-23 DOI: 10.1016/j.ipej.2026.10.005
Tak-Cheung Yung, Sabrina Tsao
{"title":"Developing an Institutional Paediatric EP Practice in Hong Kong: our reflections.","authors":"Tak-Cheung Yung, Sabrina Tsao","doi":"10.1016/j.ipej.2026.10.005","DOIUrl":"10.1016/j.ipej.2026.10.005","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149246725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Matching Electrode Configuration to Signal Sensing for Cardiac Electroanatomic Mapping: A Critical Appraisal. 匹配电极配置信号感应心脏电解剖映射:一个关键的评估。
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-21 DOI: 10.1016/j.ipej.2026.10.011
Francisco Castells, Samuel Ruipérez-Campillo, Miguel Rodrigo, Elisa Ramirez Candela, Jose L Merino, Jose Millet Roig, Sanjiv M Narayan
{"title":"Matching Electrode Configuration to Signal Sensing for Cardiac Electroanatomic Mapping: A Critical Appraisal.","authors":"Francisco Castells, Samuel Ruipérez-Campillo, Miguel Rodrigo, Elisa Ramirez Candela, Jose L Merino, Jose Millet Roig, Sanjiv M Narayan","doi":"10.1016/j.ipej.2026.10.011","DOIUrl":"https://doi.org/10.1016/j.ipej.2026.10.011","url":null,"abstract":"<p><p>The management of cardiac arrhythmias has been transformed by electroanatomical mapping, yet it is often underappreciated how dependent mapping is to electrode configuration, sensing modality, catheter geometry, and signal-processing characteristics. This review systematically evaluates how these features influence mapping, in the context of catheters in contemporary linear, circular, grid, star-shaped and basket configurations. We compare direct sensing strategies in unipolar and bipolar configurations, monophasic action potentials, and discuss post-processing approaches including omnipolar, multipolar, and Laplacian techniques. We gather evidence from computational, experimental and clinical studies to critically discuss how these considerations may influence signal acquisition and mapping resolution in the context of clinical mapping needs and, in particular, which may be most relevant for the complex arrhythmias of atrial fibrillation (AF) and ventricular tachycardia (VT). We conclude by pointing out future directions such as ultra-high-resolution mapping, adaptive catheter geometries, computational reconstruction, and AI-guided signal interpretation.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149239803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute lymphocytic myocarditis complicated by bidirectional ventricular tachycardia treated with early steroid use. 早期使用类固醇治疗急性淋巴细胞性心肌炎合并双向室性心动过速。
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-14 DOI: 10.1016/j.ipej.2026.10.009
Jessica Ross, Navya Vadlamudi, Mahmoud Houmsse
{"title":"Acute lymphocytic myocarditis complicated by bidirectional ventricular tachycardia treated with early steroid use.","authors":"Jessica Ross, Navya Vadlamudi, Mahmoud Houmsse","doi":"10.1016/j.ipej.2026.10.009","DOIUrl":"10.1016/j.ipej.2026.10.009","url":null,"abstract":"<p><p>Acute lymphocytic myocarditis can precipitate malignant ventricular arrhythmias, including the rare presentation of bidirectional ventricular tachycardia (BDVT), a rhythm associated with significant hemodynamic instability. Although BDVT is classically linked to catecholaminergic polymorphic ventricular tachycardia and digitalis toxicity, it is increasingly recognized in myocarditis, likely reflecting diffuse inflammatory involvement of the myocardium and Purkinje system. Emerging evidence suggests that early corticosteroid therapy may rapidly reduce arrhythmia burden and improve ventricular function in selected patients with active myocardial inflammation. We report the case of a 34-year-old woman who presented with palpitations and syncope and was found to have BDVT secondary to acute lymphocytic myocarditis. Despite typical medical management, she had refractory ventricular arrhythmias. Prompt initiation of corticosteroids led to marked suppression of arrhythmias and rapid recovery of left ventricular ejection fraction. While current data remain limited, this case supports the potential benefit of early immunosuppressive therapy when active lymphocytic inflammation is strongly suspected.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left pulmonary vein re-isolation and unexpected extensive posterior wall isolation with vein of Marshall ethanol infusion after cryoballoon pulmonary vein isolation and roof-line ablation. 低温球囊肺静脉分离和顶线消融后,左肺静脉再次隔离和意想不到的广泛后壁马歇尔乙醇输注静脉隔离。
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-12 DOI: 10.1016/j.ipej.2026.10.010
Yuhei Kasai, Takayuki Kitai, Junji Morita, Kazuhiro Satomi
{"title":"Left pulmonary vein re-isolation and unexpected extensive posterior wall isolation with vein of Marshall ethanol infusion after cryoballoon pulmonary vein isolation and roof-line ablation.","authors":"Yuhei Kasai, Takayuki Kitai, Junji Morita, Kazuhiro Satomi","doi":"10.1016/j.ipej.2026.10.010","DOIUrl":"https://doi.org/10.1016/j.ipej.2026.10.010","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence in Cardiac Electrophysiology Ethics, Explainability, Equity, and the Road Ahead. 人工智能在心脏电生理伦理,可解释性,公平性和未来的道路。
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-09 DOI: 10.1016/j.ipej.2026.10.008
Jiaqi Mi, Ami Bhatt, Rajesh Kabra, Dhanunjaya Lakkireddy
{"title":"Artificial Intelligence in Cardiac Electrophysiology Ethics, Explainability, Equity, and the Road Ahead.","authors":"Jiaqi Mi, Ami Bhatt, Rajesh Kabra, Dhanunjaya Lakkireddy","doi":"10.1016/j.ipej.2026.10.008","DOIUrl":"https://doi.org/10.1016/j.ipej.2026.10.008","url":null,"abstract":"<p><p>Artificial intelligence (AI) is rapidly transforming cardiac electrophysiology (EP) by enabling automated interpretation of electrocardiograms, intracardiac electrograms, wearable sensor data, and imaging modalities. These technologies promise improved diagnostic accuracy, procedural efficiency, and personalized risk stratification across a wide spectrum of arrhythmia care. However, the integration of AI into clinical EP raises important ethical, practical, and regulatory concerns. Many current models function as opaque systems with limited explainability, while training datasets often lack adequate representation across sex, race, geography, and socioeconomic status. These limitations raise the risk of biased performance, reduced generalizability, and erosion of clinician trust. Furthermore, cost, infrastructure requirements, and regulatory complexity threaten equitable global adoption. This review examines the ethical foundations of AI in electrophysiology, focusing on dataset bias, fairness, explainability, and accountability. We discuss the clinical consequences of black box models, outline strategies to improve transparency, and explore emerging regulatory and legal frameworks. Finally, we highlight future horizons including digital twins, multimodal risk engines, and real time procedural guidance systems. Responsible deployment of AI in EP will require rigorous validation, continuous monitoring, clinician oversight, and intentional efforts to ensure equitable access across diverse populations.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Back to the back wall: An issue with target, technique or patient selection? 回到后墙:目标,技术或患者选择的问题?
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-08 DOI: 10.1016/j.ipej.2026.10.006
Nayani Makkar, Abhishek Deshmukh
{"title":"Back to the back wall: An issue with target, technique or patient selection?","authors":"Nayani Makkar, Abhishek Deshmukh","doi":"10.1016/j.ipej.2026.10.006","DOIUrl":"10.1016/j.ipej.2026.10.006","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can tissue impedance reduce impediments to contact assessment during pulse field ablation procedures? 组织阻抗能否减少脉冲场消融过程中接触评估的障碍?
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-08 DOI: 10.1016/j.ipej.2026.10.007
Sheldon M Singh, Sharath K Kaup
{"title":"Can tissue impedance reduce impediments to contact assessment during pulse field ablation procedures?","authors":"Sheldon M Singh, Sharath K Kaup","doi":"10.1016/j.ipej.2026.10.007","DOIUrl":"10.1016/j.ipej.2026.10.007","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tafamidis: is it truly a game changer for transthyretin amyloid cardiomyopathy? 他法米底斯:它真的是甲状腺转蛋白淀粉样心肌病的改变者吗?
Indian Pacing and Electrophysiology Journal Pub Date : 2026-10-06 DOI: 10.1016/j.ipej.2026.10.002
Sarena Yang, Justin Hyun, Mandar A Aras
{"title":"Tafamidis: is it truly a game changer for transthyretin amyloid cardiomyopathy?","authors":"Sarena Yang, Justin Hyun, Mandar A Aras","doi":"10.1016/j.ipej.2026.10.002","DOIUrl":"10.1016/j.ipej.2026.10.002","url":null,"abstract":"<p><p>Transthyretin cardiac amyloidosis (ATTR-CM) is an increasingly recognized condition caused by the misfolding of transthyretin (TTR) protein, leading to amyloid deposits in various tissues and organs. In 2019, tafamidis was the first FDA-approved disease-modifying therapy to address an unmet need for patients with ATTR-CM, stabilizing TTR proteins and preventing dissociation. Tafamidis has been shown to reduce all-cause mortality and slow decline in functional capacity and quality of life and is generally considered a safe treatment because of its minimal major drug interactions. However, tafamidis has several well-recognized limitations, including high cost, reduced effectiveness in advanced disease stages, limited ability to address established amyloid burden, and limited evidence for advanced polyneuropathy. As new therapies and advancements emerge, further research is needed to compare their relative effectiveness. In this review, we explore the development of tafamidis, pivotal clinical trial results, clinical applications, safety considerations, and future therapeutic directions for ATTR-CM.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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