{"title":"Theory and Practice of Present Clinical Use of Quinidine in the Management of Cardiac Arrhythmias.","authors":"Bernard Belhassen, Anat Milman","doi":"10.1016/j.ipej.2025.07.017","DOIUrl":"https://doi.org/10.1016/j.ipej.2025.07.017","url":null,"abstract":"<p><p>At the beginning of the last century, quinidine had been shown to be highly effective in the management of atrial fibrillation and soon after of ventricular arrhythmias. At the end of the same century, quinidine was quickly abandoned, and its manufacturing ceased, resulting in limited accessibility across numerous countries. Paradoxically, this decline in use occurred alongside accumulating evidence supporting quinidine's therapeutic benefit in managing rare, life-threatening ventricular arrhythmias occurring in patients with no organic heart disease (Idiopathic ventricular fibrillation, Brugada syndrome, Early repolarization syndrome, Short QT syndrome, Multifocal ectopic Purkinje-related premature contractions), as well as those with organic heart disease involving the Purkinje network such as those occurring after acute myocardial infarction or in patients with hypertrophic cardiomyopathy. The present review will extensively deal with all these topics.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of sinus node dysfunction after the Fontan operation: Time to pick up the pace?","authors":"Jeremy P Moore","doi":"10.1016/j.ipej.2025.07.016","DOIUrl":"https://doi.org/10.1016/j.ipej.2025.07.016","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erick Sánchez-Rodriguez, Jose Luis Morales-Velázquez, Pio Iran Coria Sandoval, Hugo Enrique Coutiño Moreno
{"title":"ECG CHALLENGE: Focal Atrial Tachycardia Mimicking Flutter: Diagnosis Clarified by Ladder Diagrams.","authors":"Erick Sánchez-Rodriguez, Jose Luis Morales-Velázquez, Pio Iran Coria Sandoval, Hugo Enrique Coutiño Moreno","doi":"10.1016/j.ipej.2025.07.014","DOIUrl":"https://doi.org/10.1016/j.ipej.2025.07.014","url":null,"abstract":"<p><p>We present the case of a 75-year-old man with a history of hypertension, type 2 diabetes, and concentric left ventricular hypertrophy who presented with palpitations. The initial electrocardiogram suggested atrial flutter; however, detailed analysis using a ladder diagram revealed a focal atrial tachycardia with alternating 2:1 and 3:1 conduction. Some deflections initially interpreted as flutter waves were identified as T waves, highlighting the importance of differentiating true atrial activity from ventricular repolarization. The presence of exit block further supported a focal origin. This case underscores the value of ladder diagrams in accurately interpreting complex supraventricular arrhythmias.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anand Manickavasagam, Priya Chockalingam, Arthur Am Wilde
{"title":"Signature ECG 3: A case of long QT 3 syndrome (LQT3).","authors":"Anand Manickavasagam, Priya Chockalingam, Arthur Am Wilde","doi":"10.1016/j.ipej.2025.07.015","DOIUrl":"10.1016/j.ipej.2025.07.015","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endocardial Transvenous Atrial Pacing in Lateral Tunnel Fontan Guided by Electroanatomical Mapping.","authors":"Carlotta Sembenini, Alessandro Locatelli, Luca Tomasi, Giacomo Mugnai","doi":"10.1016/j.ipej.2025.07.012","DOIUrl":"https://doi.org/10.1016/j.ipej.2025.07.012","url":null,"abstract":"<p><p>The Fontan circulation is a palliative surgery used to treat cardiac abnormalities with only one well-developed ventricle. Although the surgical epicardial pacing is usually preferred, in a few cases the transvenous placement of a permanent atrial lead can be considered. The transvenous endocardial pacing is challenging because most of the right atrium is fibrotic and the lead positioning needs to be supported by a long sheath. We report a case of a transvenous lead placement from a typical left pre-pectoral pocket guided by electro-anatomical mapping.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rethinking ventricular tachycardia ablation: Insights and innovations in ischemic vs. non-ischemic cardiomyopathy.","authors":"Rajeev K Pathak, Prashanthan Sanders","doi":"10.1016/j.ipej.2025.07.013","DOIUrl":"10.1016/j.ipej.2025.07.013","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marianne Tétreault-Langlois, Mehrdad Golian, Martin S Green
{"title":"Analyzing unipolar electrograms when interpreting device interrogation tracings.","authors":"Marianne Tétreault-Langlois, Mehrdad Golian, Martin S Green","doi":"10.1016/j.ipej.2025.07.010","DOIUrl":"https://doi.org/10.1016/j.ipej.2025.07.010","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inherited arrhythmia syndromes - Cardiogenetics.","authors":"Fenna Tuijnenburg, Ahmad S Amin, Arthur A M Wilde","doi":"10.1016/j.ipej.2025.07.004","DOIUrl":"10.1016/j.ipej.2025.07.004","url":null,"abstract":"<p><p>The inherited arrhythmia syndromes long QT syndrome, Brugada syndrome and catecholaminergic polymorphic ventricular tachycardia are rare cardiac channelopathies associated with a higher risk for malignant arrhythmias and sudden cardiac death. Adequate and timely clinical management of patients remains a challenge and is often based on expert opinions and (small) cohort studies. Particularly, identification of high-risk patients continues to be difficult due to limitations in diagnostic tools and risk prediction models. Importantly, underlying causes determining the large variability in disease severity, even within families, are still unknown. A combination of rare variants in causal genes associated with the arrhythmia syndromes, non-genetic factors (i.e. age, sex) and genetic modifiers (i.e. single nucleotide polymorphisms) are thought to be of influence on the clinical phenotype and variability. Although, our knowledge regarding these rare arrhythmia syndromes has grown over the past decades, there are still gaps in knowledge that remain to be elucidated. In this review, we aim to provide an overview of the current knowledge and guidance for the clinical management of the three main arrhythmia syndromes.</p>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum regarding missing Ethical statements in previously published articles.","authors":"","doi":"10.1016/j.ipej.2025.07.007","DOIUrl":"10.1016/j.ipej.2025.07.007","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}