Journal of Food and Drug Analysis最新文献

{"title":"Development and industrial application of geographical origin identification for Taiwanese oolong tea.","authors":"Tien-Lin Liu, Jia-Ru Dai, Tsung-Chen Su, Chun-Huo Chiu, Hsien-Tsung Tsai, Chui-Feng Chiu, Jin-Chih Lin, Chih-Yi Hu","doi":"10.38212/2224-6614.3523","DOIUrl":"10.38212/2224-6614.3523","url":null,"abstract":"<p><p>Taiwanese oolong tea is renowned for its excellent quality and enjoys a prestigious reputation both domestically and internationally. In recent years, there has been an issue with imported Taiwanese-style oolong tea being sold as genuine Taiwanese oolong tea, which has adversely affected the brand value of Taiwanese oolong tea. In this study, samples of domestic oolong tea (Taiwanese oolong tea) and Taiwanese-style oolong tea produced abroad (including China, Vietnam, Indonesia, Thailand, etc.) were collected. A multi-elements analysis method was applied to establish an elemental database of tea leaf samples. Subsequently, various widely used classification methods were employed to develop a discrimination model for identifying the origin of Taiwanese oolong tea. Utilizing the discrimination model established from a database of 727 samples to determine whether the tea leaves were Taiwanese or external, the statistical performances of classification models such as LDA, Ridge, Random Forest, Boosting, and SVM are nearly consistent. These models achieved an accuracy rate of 97.1%-97.8%, a recall rate (true positive rate) for Taiwanese origin of 98.4%-99.0%, and a precision value for predicting Taiwanese origin of 97.3%-97.8%. This identification technology has become an officially recognized and publicly recommended testing method in Taiwan (TFDAF0032.00, released on November 5, 2021) and has been effectively utilized in official administrative inspections for identification of origin, as well as providing evidence for investigative cases.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"498-505"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanobactericidal nanotopographies for food industry: A promising strategy for eradicating foodborne pathogens - progress and challenges.","authors":"Deepak Patil","doi":"10.38212/2224-6614.3532","DOIUrl":"10.38212/2224-6614.3532","url":null,"abstract":"<p><p>Nowadays, food preservation, quality maintenance, and safety are major emerging concerns in the food industry. Methods for removing pathogens from the outside surfaces of food products would be an effective way to prevent bacterial contamination. Nanotopographies found on natural surfaces have been shown to mechanically damage the membranes of foodborne bacteria. Thus, using bioinspired mechanobactericidal nanostructures in food packaging and processing materials has the potential to lower surface bacterial contamination while increasing food safety. However, putting this concept into practice remains a challenge. This review discussed recent advances in understanding mechanobactericidal mechanisms, issues concerning the durability of nanotopography under external forces, and the scalability of nanostructures over larger areas. Furthermore, this review provides insight into critical research on the long-term efficiency of mechanobactericidal nanostructures and their potential for implementation in the food industry.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"385-397"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of pharmacist-managed oncology ambulatory care for patients with non-small cell lung cancer in Taiwan.","authors":"Ding-Cheng Liu, Chuan-Lun Hung, Yi-Wen Chen, Li-Na Kuo, Yen-Chun Hsin, Chun-Nan Kuo","doi":"10.38212/2224-6614.3528","DOIUrl":"10.38212/2224-6614.3528","url":null,"abstract":"<p><p>Non-small cell lung cancer (NSCLC) is commonly treated with tyrosine kinase inhibitors (TKIs). However, adverse events from such treatment can lead to treatment discontinuation and additional medical expenditures. Ambulatory care from oncology pharmacists in patient education and symptom management can benefit patients with NSCLC. In this study, we evaluated the effectiveness of an oncology pharmacy service at a medical center in Taiwan. We retrospectively enrolled 137 patients with NSCLC who initiated treatment with afatinib, gefitinib, or erlotinib between January 2017 and December 2021; 40 of them utilized the oncology pharmacy service (intervention group), and the remaining 97 did not (nonintervention group). To determine the effectiveness of the oncology pharmacy service, we analyzed the following outcomes: adverse event rates, number of hospital visits (unexpected outpatient department visits, emergency department visits, and hospitalization), and medical expenditure. The intervention group had significantly more skin-related adverse events (acneiform rash: 75% vs. 49%; mucositis: 40% vs. 21%; dermatitis: 30% vs. 9%; and paronychia: 85% vs. 28%) but significantly fewer monthly emergency department visits (0.04 vs. 0.17) and unexpected outpatient department visits (0.15 vs. 0.34). The intervention group also had significantly lower expenditure for emergency department visits (NT$166.4 vs. NT$734.8) and nonsignificantly lower expenditure for outpatient department visits. Our findings indicate the value of pharmacist-managed ambulatory oncology care. Although this service did not reduce the incidence rates of adverse events, it reduced the number of unplanned outpatient and emergency department visits and reduced the emergency department expenditure of patients with NSCLC receiving TKIs.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"558-567"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorescent \"on-off-on\" sensor based on N, P co-doped carbon nanoparticles for specific detection of Fe³⁺ and ascorbic acid.","authors":"Li Li, Ming Zhang, Xiang Liu, Shaoqing Zhu","doi":"10.38212/2224-6614.3533","DOIUrl":"10.38212/2224-6614.3533","url":null,"abstract":"<p><p>Ascorbic acid (AA) is used as a food additive for its antibacterial and antioxidant properties. However, excessive intake of AA is harmful to humans. Therefore, the detection of Fe³⁺ and AA is generally recognized to be meaningful. In this work, a one-step hydrothermal tactics is developed for the preparing nitrogen and phosphorus co-doped carbon nanoparticles (N, P-CNPs) by using sucrose and ammonium orthophosphate as raw materials. The N, P-CNPs not only exhibited an enhanced fluorescent efficiency with a relatively high quantum yield up to 28%, but also showed satisfactory stability, water solubility and photostability. The fluorescence of N, P-CNPs can be effectively quenched by Fe³⁺ by a combination of inner filter effect (IFE) and static quenching and recovered upon the addition of AA due to the easy conversion of Fe³⁺ to reduced states Fe²⁺ by AA. Therefore, a turn-off-on fluorescent sensing strategy can be constructed for sequential detection of Fe³⁺ and AA with detection limits of 0.03 μM and 6 nM with the corresponding linear ranges of 0.05-500 μM and 0.01-500 μM respectively. The proposed fluorescent sensor exhibits excellent sensing performance and has been applied to the determination of Fe³⁺ in tap water and the analyses of AA in canned fruit soup with satisfactory results. Therefore, this fluorescent sensor expressed high potential in water quality monitoring, and could be further used to be a tool for practical food additives detection.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"544-557"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic approach of carbon nanotube: Revolutionize nanomaterial in biomedical and pharmaceutical sector.","authors":"Shovan Ghosh, Vivek Dave, Pranay Wal","doi":"10.38212/2224-6614.3531","DOIUrl":"10.38212/2224-6614.3531","url":null,"abstract":"<p><p>Carbon nanotubes (CNTs) has emerged as a promising nanomaterial with a wide range of potential applications due to their unique structural, mechanical, electrical, and thermal properties. However, numerous obstacles must be overcome for CNTs to be used successfully, including low solubility, aggregation, and a lack of specialized functions. Diverse techniques have been developed for the manufacture, purification, and functionalization of CNTs in order to overcome these issues. The main aim of this review article is to provide brief knowledge about CNTs and strategies to use this revolutionized nanomaterial in drug delivery. Prepare CNTs cannot be directly used as drug carrier molecules due to the presence of impurities, so purification is an essential aspect of their use. In addition, various functionalization procedures are used frequently for drug conjugation with other benefits, such as reduced toxicity and targeted delivery. Their nano needle structure can penetrate any cell without damaging it with improved efficiency in targeted drug delivery, cancer cell identification, anticancer molecule delivery, antifungal treatment, and transdermal approaches. This nanostructure also has some antimicrobial activity, and conjugation with some antimicrobial agents shows a synergistic response.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"412-427"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bio-inspired chitosan/polydopamine-nanoparticle based sorbent bead: A versatile platform for separation and HPLC analysis of tetracycline antibiotics from various sample matrix.","authors":"Emmanuvel Arputharaj, Yu-Hui Huang, Shivangi Singh, Chen-Han Zhuang, Kuei-Ying Lin, Sri Sudewi, You-Rong Wu, Yeou-Lih Huang","doi":"10.38212/2224-6614.3510","DOIUrl":"10.38212/2224-6614.3510","url":null,"abstract":"<p><p>This study introduces an innovative bio-based sorbent bead crafted by integrating chitosan (CS) biopolymers, Fe(NO3)3 and polydopamine nanoparticles (PDA NPs) via glutaraldehyde crosslinking. The primary focus of this study was the concurrent separation of diverse tetracycline antibiotics (TCs), followed by rigorous reversed-phase liquid chromatography analysis. The fabricated CS/Fe@PDA sorbent beads were comprehensively characterized using scanning electron microscopy and energy-dispersive X-ray spectroscopy, revealing a surface rich in active carbon (C), nitrogen (N), and oxygen (O) moieties. The proposed method demonstrated substantial analytical robustness, enabling the sorbent bead to detect low concentrations of TCs, with limit of detection values ranging from 142 to 303 μg L-1. Notably, the established linear range of 450-2000 μg L-1 extended the applicability of this approach to food and pharmaceutical product analysis. This study anticipated a paradigm shift in sample pre-treatment methodologies for TC analysis and envisions CS/Fe@PDA beads as a valuable tool for further advancements in separation science. The proposed bio-sorbent introduced a promising avenue for optimizing TC analysis, contributing to broader goals of food safety and pharmaceutical quality assurance. The results and insights from this study are expected to provide valuable inputs for ongoing efforts of the Food and Drug Administration to enhance analytical methodologies for food and drug safety.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"520-531"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herbal nanoemulsions in cosmetic science: A comprehensive review of design, preparation, formulation, and characterization.","authors":"Benni Iskandar, Ta-Wei Liu, Hui-Ching Mei, I-Chih Kuo, Meircurius Dwi Condro Surboyo, Hsiu-Mei Lin, Ching-Kuo Lee","doi":"10.38212/2224-6614.3526","DOIUrl":"10.38212/2224-6614.3526","url":null,"abstract":"<p><p>The rapid development of delivery systems for cosmetics has revealed two critical challenges in the field: enhancing the solubility of active ingredients and ensuring the stability of natural materials used in cosmetics. Nanoemulsion technology has emerged as an indispensable solution for addressing these challenges, not only enhancing the stability of cosmetics but also improving the solubility of pharmaceuticals and active ingredients with poor solubility. Nanoemulsion formulations have reinforced stability and amended the bioavailability of hydrophobic drugs. Moreover, nanoemulsion exhibit excellent skin penetration and long-lasting effects, making them particularly appealing to consumers, especially in the cosmetic industry. This article aims to provide an overview of herbal nanoemulsion formulations as cosmetic products, covering formulation, production, and characterization. Herbal nanoemulsions is an effective, stable, and promising option for cosmetic delivery. The nanoemulsions were characterized by their key properties, such as particle size, polydisperse index (PDI), zeta potential, viscosity, stability and others. Techniques like zeta potential measurement, transmission electron microscopy (TEM) and scanning electronmicroscopy (SEM) were used to analyze the surface morphology, whereas stability tests were employed to evaluate nanoemulsion performance. This review also delves into the high-energy and the low-energy methods of manufacturing nanoemulsions. Additionally, we also explore the selection of appropriate surfactants, co-surfactants, and ingredients for creating herbal nanoemulsions with desirable attributes and qualities. Overall, this review consolidates the current knowledge on herbal nanoemulsion formulations for cosmetic preparations, designs, shedding light on their effectiveness, characteristics, and stability. These formulations hold promise in overcoming challenges related to meeting the increasing demand for effective herbal nanoemulsion and high-quality cosmetic products.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"428-458"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of fermentation by different species of lactic acid bacteria on betalains and polyphenol profile and in vitro bioactive potential of red beetroot juice.","authors":"Tomasz Sawicki, Monika Jabłońska, Małgorzata Starowicz, Lucyna Kłębukowska, Wioletta Błaszczak","doi":"10.38212/2224-6614.3515","DOIUrl":"10.38212/2224-6614.3515","url":null,"abstract":"<p><p>In the current study, the effects of fermentation by Lactobacillus acidophilus, Levilactobacillus brevis or Lactiplantibacillus plantarum (La/Lb/Lp, 1-2.5%) and incubation (30/37 °C, C1/C2) of red beetroot juice on the profile of betalains and polyphenols (UHPLC-DAD-MS), and antioxidant capacity using photochemiluminescence (PCL) and spectrophotometric assays (DPPH/ABTS) was investigated. Additionally, anti-glycaemic (anti-AGEs) and anticholinergic (anti-AChE) potential in vitro was analysed. Fermentation distinctly initiated isobetanin and neobetanin formation and enhanced flavonoid concentration, emphasising rutin, kaempferol and (+)-catechin. The fermented juices inhibited protein glycation in the BSA-GLU model and showed high DPPH and ABTS values. LP2.5% juice was the only one indicating anti-AChE potential.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"482-497"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledgment of reviewers.","authors":"","doi":"10.38212/2224-6614.3538","DOIUrl":"https://doi.org/10.38212/2224-6614.3538","url":null,"abstract":"","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"i"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aromatic compounds and organic acids identified from Ganoderma formosanum exhibit synergistic anti-melanogenic effects.","authors":"Chen-Che Hsieh, Chih-Yao Hou, Hsiao-Yun Lei, Darin Khumsupan, Huey-Jine Chai, Pek-Kui Lim, Cheng-Chih Hsu, Sz-Jie Wu, Kai-Wen Cheng, Yi-Chen Chen, Kuan-Chen Cheng","doi":"10.38212/2224-6614.3509","DOIUrl":"10.38212/2224-6614.3509","url":null,"abstract":"<p><p>This study reveals the anti-tyrosinase activity of Ganoderma formosanum extracts, pinpointing compounds including gluconic acid, mesalamine, L-pyroglutamic acid, esculetin, 5-hydroxyindole, and salicylic acid, as effective melanin production inhibitors in melanoma cells and zebrafish embryos. Furthermore, multiple molecular docking simulations provided insights into interactions between the identified compounds and tyrosinase, increasing binding affinity up to -16.36 kcal/mol. The enhanced binding of identified compounds to tyrosinase facilitated synergistic inhibitory effects on melanin production. This study highlights the potential of GFE-EA as a source of natural tyrosinase inhibitors and contributes to understanding the role of active compounds extracted from G. formosanum.</p>","PeriodicalId":358,"journal":{"name":"Journal of Food and Drug Analysis","volume":"32 4","pages":"532-543"},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}