Therapeutic approach of carbon nanotube: Revolutionize nanomaterial in biomedical and pharmaceutical sector.

IF 2.6 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY
Shovan Ghosh, Vivek Dave, Pranay Wal
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Abstract

Carbon nanotubes (CNTs) has emerged as a promising nanomaterial with a wide range of potential applications due to their unique structural, mechanical, electrical, and thermal properties. However, numerous obstacles must be overcome for CNTs to be used successfully, including low solubility, aggregation, and a lack of specialized functions. Diverse techniques have been developed for the manufacture, purification, and functionalization of CNTs in order to overcome these issues. The main aim of this review article is to provide brief knowledge about CNTs and strategies to use this revolutionized nanomaterial in drug delivery. Prepare CNTs cannot be directly used as drug carrier molecules due to the presence of impurities, so purification is an essential aspect of their use. In addition, various functionalization procedures are used frequently for drug conjugation with other benefits, such as reduced toxicity and targeted delivery. Their nano needle structure can penetrate any cell without damaging it with improved efficiency in targeted drug delivery, cancer cell identification, anticancer molecule delivery, antifungal treatment, and transdermal approaches. This nanostructure also has some antimicrobial activity, and conjugation with some antimicrobial agents shows a synergistic response.

碳纳米管的治疗方法:革新生物医学和制药领域的纳米材料。
碳纳米管(CNTs)由于其独特的结构、机械、电学和热性能,已成为一种具有广泛应用前景的纳米材料。然而,要成功使用碳纳米管,必须克服许多障碍,包括低溶解度、聚集性和缺乏专门功能。为了克服这些问题,人们开发了各种各样的技术来制造、纯化和功能化碳纳米管。这篇综述文章的主要目的是提供关于碳纳米管的简要知识和在药物递送中使用这种革命性纳米材料的策略。制备的CNTs由于存在杂质,不能直接用作药物载体分子,因此纯化是其使用的一个重要方面。此外,各种功能化程序经常用于具有其他益处的药物偶联,例如降低毒性和靶向递送。他们的纳米针结构可以穿透任何细胞而不破坏它,提高了靶向药物传递、癌细胞识别、抗癌分子传递、抗真菌治疗和透皮途径的效率。该纳米结构还具有一定的抗菌活性,与某些抗菌剂偶联后表现出协同反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Food and Drug Analysis
Journal of Food and Drug Analysis 医学-食品科技
CiteScore
6.30
自引率
2.80%
发文量
36
审稿时长
3.8 months
期刊介绍: The journal aims to provide an international platform for scientists, researchers and academicians to promote, share and discuss new findings, current issues, and developments in the different areas of food and drug analysis. The scope of the Journal includes analytical methodologies and biological activities in relation to food, drugs, cosmetics and traditional Chinese medicine, as well as related disciplines of topical interest to public health professionals.
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