Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru最新文献

{"title":"[Hepatitis and olmesartan-induced enteropathy: an uncommon association. A case report].","authors":"Miguel Ramírez Verdyguer, Eduardo Tavío Hernández, Amanda Rodríguez Villena, Cristian Perna Monroy, Daniel Alvarez de Castro, Francisco José Manzano Gómez, Sandra Pérez de la Iglesia, Agustín Albillos Martínez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Olmesartan is a widely prescribed antihypertensive agent. While the most frequent adverse reactions include headache, influenza-like symptoms, and dizziness, sprue-like enteropathy-characterized by chronic diarrhea and intestinal villous atrophy that does not improve with a gluten-free diet-has also been documented. Hepatic involvement attributable to olmesartan is far less well known: clinical trials reported mild aminotransferase elevations in fewer than 2% of participants, a rate comparable to placebo. Nevertheless, in recent years several cases of severe acute hepatitis with variable latency periods have been published. The simultaneous occurrence of both potentially serious adverse effects is exceptionally uncommon, with only two patients described in the literature to date. We report the case of a 66-year-old woman receiving long-term therapy with a fixed combination of olmesartan medoxomil, amlodipine, and hydrochlorothiazide. More than two years after treatment initiation she developed chronic diarrhea (4-6 bowel movements per day). Months later, during an exacerbation of the diarrhea that produced hydro-electrolyte disturbances requiring hospitalization, she experienced jaundice and profound liver function test abnormalities, prompting an exhaustive investigation of both clinical pictures. After an extensive work-up, concomitant olmesartan-induced enteropathy and hepatotoxicity was suspected. Cessation of the drug led to complete resolution of symptoms and normalization of all laboratory parameters.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"408-412"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Eosinophilic gastroduodenitis secondary to toxocariasis: a zoonosis simulating gastric lymphoma in children].","authors":"Carlos Augusto Cuadros Mendoza, Yennifer Fernanda Santander Díaz, Johon Francisco Garcés Camacho, Viviana Parra Izquierdo, José Antonio Vargas Soler, Kelly Johana Paz Amador, Adriana Patricia Pinilla Orejarena, Adriana Lucía Castillo Rincón, Silvia María Toscano Rodríguez, Camilo Andrés Pérez Montiel, Johana Andrea Navarro Mejía","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We describe the case of a pediatric patient with eosinophilic gastroduodenitis secondary to visceral toxocariasis, presenting with clinical, endoscopic, and histological features suggestive of gastric lymphoma. The patient, from a rural area, exhibited severe gastrointestinal symptoms, persistent hypereosinophilia, deep ulcerative lesions in the stomach and duodenum, as well as systemic involvement. After an extensive immunological, hematological, and infectious disease evaluation, the diagnosis was confirmed by positive serology for Toxocara canis. The patient showed favorable clinical evolution with antiparasitic therapy, immunomodulation, and intensive nutritional support. This case highlights the importance of considering infectious etiologies in the differential diagnosis of eosinophilic gastroduodenal disorders, particularly in pediatric patients with systemic involvement and a presentation mimicking malignant disease.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"413-418"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Anomalous biliopancreatic junction, a rare etiology of recurrent pancreatitis].","authors":"Dagoberto Rafael Duarte Misol, Mario Fernando Prada Rivera, Juliana Celedon Moy, Marco Antonio Medina Ortega, Jesús Maria Pérez Orozco","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Anomalous biliopancreatic junction is a very rare condition, with very low incidences in Asia, 1:1000 inhabitants and even lower in the West, up to 1:100,000. Endoscopic retrograde cholangiopancreatography is the diagnostic imaging technique of choice. This condition involves the junction of the biliary and pancreatic ducts outside the duodenal wall, predisposing patients to reflux of bile and pancreatic juice, which increases the risk of recurrent acute pancreatitis. Therefore, timely diagnosis and appropriate treatment are crucial.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"426-428"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Classifications for the endoscopic report: a practical guide for residents].","authors":"Harold Benites-Goñi, Dacio Cabrera, Mirko Espejo, Jaqueline Abad, Jessica Alférez, Milagros Dávalos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>At the conclusion of an endoscopic procedure, we must prepare a report of the observed findings. However, the generated report is not only intended to describe and list what was detected during the endoscopy. The endoscopy report should serve as a relevant tool that not only improves communication among medical staff, but also supports subsequent clinical decision-making through a clear diagnosis. This objective can be achieved by systematizing our reports through the routine use of validated classifications and scales. Nevertheless, their use is often complex and not regularly applied, particularly among endoscopists in training. For this reason, we present the following narrative review, aimed at providing gastroenterologists in training with the most important classifications, explained in a simple manner and accompanied by updated references.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"434-446"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance assessment of gastrointestinal tract inflammation in Crohn's disease using the simplified MaRIA score In a Colombian center: MAGNETIC study.","authors":"Viviana Parra Izquierdo, Juan Sebastián Frías-Ordoñez, Ginary Orduz Diaz, Oscar Mariano Pinto, Carlos Augusto Cuadros, Johon Francisco Garcés, Juan Javier Acevedo, Andrés Guillermo Barco, Danilo Solorzano, Julian Ferreira, Vanessa Duran, Cristian Fabián Flórez, Juancarlos Torres, Maria Stella Serrano, Samuel Cubillos Rodríguez","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Magnetic Resonance Enterography (MRE) is a valuable imaging modality for the evaluation and follow-up of patients with inflammatory bowel disease (IBD), particularly Crohn's disease (CD). This study describes MRE findings in patients with suspected or confirmed CD at a national reference center for IBD in Colombia.</p><p><strong>Materials and methods: </strong>A descriptive observational study was conducted in patients evaluated with MRE at a specialized IBD center.</p><p><strong>Results: </strong>Of the 20 patients evaluated, 18 (90%) underwent MRE due to clinical or endoscopic suspicion of Crohn's disease, while 2 patients (10%) had a previously confirmed diagnosis and were assessed for follow-up evaluation. Overall, 40% of the cohort showed findings compatible with acute inflammatory activity. Overall, 40% of the cohort showed findings compatible with acute inflammatory activity. Intestinal involvement was most frequent in the terminal ileum (40%), followed by the sigmoid colon (15%), and the descending, transverse, and cecum colon (10% each). The average ileal segment length was 37 mm, with mean parietal thickening of 5.7 mm. Mesenteric fat signal alteration was observed in 55% of patients, mesenteric lymphadenopathy in 35%, and vascular changes in 10%. Chronic fibrostenotic changes were found in 15%, and 20% showed subocclusive-type obstructions. Findings not related to IBD were noted in 35% of cases. Based on the simplified Magnetic Resonance Index of Activity (MaRIA) score, 50% had a score of 0-1, 5% scored 2, 40% scored 3, and 5% scored 5.</p><p><strong>Conclusions: </strong>The MAGNETIC study confirms MRE's role in identifying active inflammation, chronic sequelae, and complications in Crohn's disease. It supports the use of the MaRIA score for objective disease assessment, enhancing clinical decision-making in specialized IBD centers.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"374-380"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"White light imaging versus artificial intelligence-assisted white light imaging for colorectal neoplasia detection: a randomised trial.","authors":"Carlos Eduardo Oliveira Dos Santos, Cadman Leggett, Prateek Sharma, Gabriel Malaman Dos Santos, Ivan David Arciniegas Sanmartin, Júlio Carlos Pereira-Lima","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Adenoma detection rate (ADR) and sessile serrated lesion (SSL) detection rate (SDR) are crucial quality indicators for colonoscopy, as their improvement contributes to effective prevention of colorectal cancer. Artificial intelligence (AI) has been shown to significantly increase ADR. This study compared white light imaging (WLI) versus AI-assisted WLI for neoplasia detection.</p><p><strong>Materials and methods: </strong>This was a prospective, randomised trial of screening, surveillance, and symptomatic patients. Our primary objective was to evaluate ADR. Secondary objectives included SDR, mean number of adenomas per patient (MAP), neoplasia detection rate (NDR), advanced ADR (AADR), and colonoscope withdrawal time.</p><p><strong>Results: </strong>A total of 621 adenomas were diagnosed in 711 patients, with 310 adenomas in the WLI group and 311 adenomas in the WLI+AI group (p=0.65). Eighty-three SSLs and two intramucosal carcinomas were also detected, totalling 706 neoplasms. ADR was 45.9% in the WLI group and 50.8% in the WLI+AI group (p=0.20). ADR was 54.4% for screening, 49.0% for surveillance, and 40.0% for symptomatic patients (p=0.01). Marginal significance was observed in the WLI+AI group for screening patients (61.5% vs. 49.2%, p=0.06). SDR was 9.0% for both groups. MAP (0.9 vs. 0.9, p=0.34), NDR (51.0% vs. 56.8%, p=0.13), and AADR (8.4% vs. 7.6%, p=0.78) did not differ significantly between the groups. Withdrawal time was similar for the WLI (12.4 ± 5.1 min) and WLI+AI (12.2 ± 4.1 min) groups (p=0.32).</p><p><strong>Conclusions: </strong>AI-assisted colonoscopy demonstrated high ADR and NDR. While without statistical relevance overall, marginal significance was observed for screening patients.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"359-366"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Multidisciplinary approach to dysphagia: literature review and clinical perspectives].","authors":"Natalia M Barrón Cervantes, Jorge Espinoza-Ríos, Carla Guerrero, Luis R Valdovinos García","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dysphagia is defined as an alteration in the swallowing process, which is divided into two phases: oropharyngeal and esophageal. Identifying the location of the disorder is essential for guiding the diagnostic evaluation. Oropharyngeal dysphagia is mainly associated with chronic neurological diseases, as well as structural causes such as Zenker's diverticulum, certain neoplasms, or medication-related factors. Esophageal dysphagia, on the other hand, may result from obstruction (strictures, Schatzki rings, cancer), motility disorders (achalasia, distal esophageal spasm), or inflammatory processes, with gastroesophageal reflux disease and eosinophilic esophagitis being the most common causes. The initial clinical assessment, based on symptoms, helps guide further diagnostic studies. If oropharyngeal dysphagia is suspected, laryngoscopy should be performed and the patient referred to an otolaryngologist or a speech-language pathologist. In cases of suspected esophageal dysphagia, endoscopy and esophagography are recommended. Impedance pH monitoring, manometry, and computed tomography are indicated when specific diagnoses are suspected.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"390-397"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Perception of work-life balance and professional performance among Venezuelan female gastroenterologists: a pioneering study].","authors":"Carla Dias, Suhey Pérez, Mercedes De Sousa, Yolette Martínez, Nina Colina, Maria Laura Salazar, Michelina Lafigliola, Lisbeth Mendoza, Yaritza Méndez, Yulidza Hurtado, Evelin Spitali, Solangel Rodriguez, Solangel Diaz, María Alejandra Chauran, Yaneth Flores, Antoinette Khoury","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Worldwide, women represent a significant part, and even the majority, of medical personnel, evidencing a global trend towards the feminization of the profession. However, challenges persist in gender equality in leadership and academic roles. Understanding how women endoscopists manage the delicate balance between their demanding careers and personal lives is crucial to ensuring equitable professional environments.</p><p><strong>Objective: </strong>This research thoroughly explored these dynamics, seeking to understand the unique challenges, coping strategies and factors that influence the successful integration of personal and professional life for these specialists.</p><p><strong>Materials and methods: </strong>a survey was designed that addressed aspects of personal life, academic training, incorporating the Maslach Burnout Inventory (MBI) and the adapted MacDonald and MacIntyre job satisfaction scale.</p><p><strong>Results: </strong>The non-probabilistic sample included 202 female endoscopists aged between 29 and 73 years. It was found that those with children perceived difficulties in career advancement and a lack of workplace support during child-rearing. Nevertheless, there were no significant differences between women with and without children in the perception of workplace discrimination, professional advancement opportunities, or specialized training capabilities. A negative relationship was found between age and the perception of burnout. Job satisfaction, in turn, showed no correlation with any personal variables.</p><p><strong>Conclusion: </strong>These results suggest that, while motherhood imposes work-life balance challenges, professional experience may mitigate burnout, regardless of job satisfaction. Support and mentorship policies are required to achieve an inclusive environment.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"381-389"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence of Barrett's esophagus and factors associated with the diagnosis of dysplasia or adenocarcinoma in patients evaluated at a Chilean university endoscopy center].","authors":"Alberto Espino, María Jesús Fuenzalida, Gonzalo Latorre, Felipe Silva, Oscar Corsi, Renato Palma, Javiera Torres, Rodrigo Nieto, Valentina Constanzo, Gabriela Fuentes, Mario Nilo, Leonardo Salgado, Cristóbal Vargas, José Ignacio Vargas","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Esophageal adenocarcinoma (EAC) is increasing in Western countries, and Barrett's esophagus (BE) represents its only known premalignant condition. BE affects approximately 1-2% of the general population and up to 14% of patients with gastroesophageal reflux disease (GERD). Data from Latin America and Chile remain limited.</p><p><strong>Objectives: </strong>To determine the prevalence of BE, the neoplasia detection rate (NDR), and the endoscopic quality criteria associated with neoplasia detection in a Chilean university center.</p><p><strong>Materials and methods: </strong>A longitudinal cohort study including all patients with BE identified among upper gastrointestinal endoscopies performed at the Red de Salud UC CHRISTUS between January 2015 and December 2022. Patients with a history of other digestive neoplasms or referred with previously diagnosed BE/EAC were excluded. Demographic, endoscopic, and histopathological variables were analyzed. BE prevalence was defined as the number of histologically confirmed BE cases over the total diagnostic endoscopies performed during the study period. NDR was defined as the presence of high-grade dysplasia (HGD) or EAC on index endoscopy among BE patients. Multivariable logistic regression was applied to identify factors independently associated with NDR.</p><p><strong>Results: </strong>A total of 422 patients were diagnosed with BE (62% men; mean age 58 years, range 17-87). The overall prevalence of BE was 0.46% (422/91,723), increasing from 0.33% in 2015 to 0.72% in 2022. The low-grade dysplasia detection rate was 3.8% (16/422) and the NDR 1.7% (7/422). The mean BE length was 3,7 cm (range 1-18 cm). The Prague classification and chromoendoscopy were reported in 66% (280/422) and 44% (185/422) of procedures, respectively. Factors independently associated with neoplasia detection were age (OR 1.08; 95% CI 1.01-1.16), use of chromoendoscopy (OR 10.1; 95% CI 1.03-96), and presence of a visible lesion (OR 43.7; 95% CI 4.9-393).</p><p><strong>Conclusion: </strong>The prevalence of BE in this Chilean cohort was 0.46%, showing an upward trend approaching international reports. The use of chromoendoscopy and the detection of visible lesions were independently associated with higher neoplasia detection, underscoring the importance of adherence to endoscopic quality standards in BE evaluation.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"367-373"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Unusual presentation of Crohn disease associated with hemophagocytic lymphohistiocytosis syndrome: a case report].","authors":"Carlos Augusto Cuadros Mendoza, Johon Francisco Garces Camacho, Liz Mary Lacouture Acuña, Viviana Parra Izquierdo, Adriana Lucia Castillo Rincón, Silvia María Toscano Rodríguez, Delbert Giovany Beltrán Avendaño, José Antonio Vargas Soler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Crohn's disease (CD) is a chronic, multifactorial inflammatory condition that can affect any part of the gastrointestinal tract and is associated with systemic, extraintestinal, and atypical manifestations. Hemophagocytic lymphohistiocytosis (HLH), also known as macrophage activation syndrome, is a rare and severe inflammatory disorder that may occur secondary to infections, malignancies, or autoimmune diseases. Its association with CD is extremely uncommon. We report the case of an 8-year-old male who initially presented with nonspecific symptoms including lower limb pain, lumbalgia, and progressive abdominal pain, evolving into respiratory failure and cardiogenic shock, which required admission to the intensive care unit (ICU). He developed bicytopenia, persistent fever, rash, bilateral pleural effusion, hyperferritinemia, hypertriglyceridemia, and signs of systemic inflammation, raising clinical suspicion for HLH. Infectious and hematologic malignancies were ruled out. The patient received intravenous immunoglobulin, broad-spectrum antibiotics, antifungal agents, and immunomodulatory treatment. Gastrointestinal symptoms included melena-like diarrhea, hematochezia, abdominal distension, and elevated fecal calprotectin levels. Abdominal CT imaging showed colonic wall thickening and mesenteric lymphadenopathy. Esophagogastroduodenoscopy, colonoscopy, and histopathological analysis confirmed the diagnosis of CD. Treatment with infliximab was initiated, leading to a favorable clinical response. This case underscores an atypical presentation of CD associated with HLH, posing significant diagnostic and therapeutic challenges.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"429-433"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}