Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru最新文献

[Lymphocytic esophagitis as a cause of dysphagia: a case report and brief literature review]. [淋巴细胞性食管炎引起吞咽困难：1例报告及简要文献复习]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Javier Perez-Valenzuela, Manuel Barrera, María Francisca Vergara, Javier Chahuán

{"title":"[Lymphocytic esophagitis as a cause of dysphagia: a case report and brief literature review].","authors":"Javier Perez-Valenzuela, Manuel Barrera, María Francisca Vergara, Javier Chahuán","doi":"","DOIUrl":"","url":null,"abstract":"Lymphocytic esophagitis (LyE) is a chronic inflammatory condition of the esophagus with a prevalence of ~0.1% among esophageal biopsies. The main clinical manifestations are dysphagia, heartburn, and chest pain; some endoscopic findings includes rings, strictures, and furrows. We present the case of a patient with diagnosis of LyE. A 63-year-old woman with Sjögren syndrome and treated hypothyroidism presented with a 1-year history of progressive solid-food dysphagia and 4-kg weight loss. Endoscopy and a barium esophagogram revealed a proximal esophageal web, which was treated with endoscopic dilation. A follow-up esophagogastroduodenoscopy showed esophageal rings and luminal narrowing. Biopsies confirmed LyE. She was treated with esomeprazole with good clinical response. LyE is a recently described entity in which clinicopathologic correlations are not always straightforward. Given overlap in symptoms and endoscopic features, eosinophilic esophagitis is the principal differential diagnosis. Management options include proton-pump inhibitors, swallowed topical corticosteroids, and esophageal dilation for fixed strictures. Clear, evidence-based clinical guidelines are still lacking.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"46 1","pages":"74-77"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Welcome the partnership between the Pan American Organization for Crohn's and Ulcerative Colitis and the Revista de Gastroenterología del Perú]. [欢迎泛美克罗恩病和溃疡性结肠炎组织与Gastroenterología del Perú杂志之间的伙伴关系]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Fabián Juliao-Baños

引用次数: 0

[Exocrine pancreatic insufficiency and hyperoxaluria: a preventable renal complication from gastroenterology]. [外分泌胰功能不全和高血氧症：一种可预防的胃肠病学肾脏并发症]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Ernesto Hornung, Ignacio Moratorio, Serena Amor, Mariana Seija, Adrián Canavesi

{"title":"[Exocrine pancreatic insufficiency and hyperoxaluria: a preventable renal complication from gastroenterology].","authors":"Ernesto Hornung, Ignacio Moratorio, Serena Amor, Mariana Seija, Adrián Canavesi","doi":"","DOIUrl":"","url":null,"abstract":"Exocrine pancreatic insufficiency (EPI) is the inability of the pancreas to produce essential digestive enzymes for fat metabolism, leading to systemic and nutritional repercussions. Although its manifestations are typically digestive, systemic complications such as enteric hyperoxaluria can occur. We present a 68-year-old man with insulin-dependent diabetes mellitus, who developed steatorrheic diarrhea and significant weight loss. Computed tomography revealed an atrophic pancreas with diffuse calcifications. Based on a diagnosis of chronic pancreatitis, pancreatic enzyme replacement therapy (PERT) was initiated empirically with clinical improvement. Three years later, while asymptomatic from a gastrointestinal perspective, he developed bilateral calcium oxalate nephrolithiasis progressing to end-stage renal disease, requiring hemodialysis. This was interpreted as oxalate nephropathy secondary to enteric hyperoxaluria, favored by suboptimal PERT dosing and poor follow-up adherence. PERT was optimized to 40,000 units per meal with good nutritional and digestive outcomes. The etiological study for EPI showed no obstructive or systemic causes. This case highlights the importance of suspecting EPI when systemic complications like secondary hyperoxaluria appear. Early diagnosis remains challenging and requires close monitoring, as specific guidelines to prevent irreversible renal damage are lacking; early recognition can significantly improve prognosis and quality of life.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"46 1","pages":"78-81"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of early rectal cancer with massive submucosal invasion using endoscopic intermuscular dissection: a case report. 内镜下肌间剥离术治疗早期直肠癌伴粘膜下肿大浸润1例。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Romario Ruiz, Paulo Bardalez-Cruz, Luis Marin-Calderón, Maria Kapsoli, Harold Benites-Goñi

{"title":"Management of early rectal cancer with massive submucosal invasion using endoscopic intermuscular dissection: a case report.","authors":"Romario Ruiz, Paulo Bardalez-Cruz, Luis Marin-Calderón, Maria Kapsoli, Harold Benites-Goñi","doi":"","DOIUrl":"","url":null,"abstract":"The management of early rectal cancer is shifting toward organ-preserving strategies. Endoscopic submucosal dissection (ESD) achieves en bloc resections for low-risk T1 lesions, while surgery remains the gold standard for deep submucosal invasion due to the risk of nodal metastasis. Endoscopic intermuscular dissection (EID) has emerged as an alternative in selected high-risk patients. We report the case of a 71-year-old man with chronic kidney disease and ischemic heart disease, in whom a 15 mm sessile rectal lesion with features of deep invasion was detected. EID achieved complete resection without complications, and MRI confirmed cT1-2N0 disease. Histopathology revealed moderately differentiated adenocarcinoma with deep invasion, lymphovascular invasion, and grade 2 tumor budding. Given surgical contraindications, active surveillance was chosen after multidisciplinary discussion. At six months, the patient remains recurrence-free. Unlike conventional ESD, EID allows dissection between the inner circular and outer longitudinal muscle layers, improving deep margins in sm2-sm3 lesions. Evidence suggests that lymphovascular invasion, tumor budding, and poor differentiation are the strongest predictors of nodal metastasis. In selected patients, EID may provide curative resection while avoiding major surgery. Careful risk stratification and multidisciplinary evaluation are essential to balance oncologic safety and organ preservation.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"46 1","pages":"71-73"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Treatment patterns in inflammatory bowel disease in Panama: experience from a specialized center]. [巴拿马炎症性肠病的治疗模式：来自一个专业中心的经验]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Carlos Rettally, Valeria Orillac

{"title":"[Treatment patterns in inflammatory bowel disease in Panama: experience from a specialized center].","authors":"Carlos Rettally, Valeria Orillac","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Inflammatory bowel disease has shown a sustained increase in incidence in developing countries. In Panama, there are no previous reports describing treatment patterns or the use of biologic therapies. The objective is to describe the therapeutic patterns in patients with ulcerative colitis and Crohn's disease, including the use of conventional and advanced therapies, as well as prior exposure to biologic agents in real-world clinical practice.Materials and methods: This was an observational, descriptive, and retrospective study of adult patients with Crohn's disease or ulcerative colitis treated between 2009 and 2024 at a gastroenterology clinic in Panama City.Results: 140 patients were included, with the majority (65%) diagnosed within the last decade. At the time of the last evaluation, 35% were receiving immunomodulators, 33.6% aminosalicylates, 21.4% turmeric and Qing Dai, 7.9% corticosteroids, and 40.7% biologic therapies; 12.1% were not on active treatment. Among patients on biologic therapy, 63.2% were using anti-TNF agents, and 45.6% had received at least one previous biologic. Intestinal surgery was documented in 17.9% of the cohort.Conclusions: High penetration of biological therapies was observed, with significant use of non-anti-TNF agents and the need for multiple lines of treatment in refractory cases. The limited use of aminosalicylates and the pioneering incorporation of turmeric-Qing Dai differentiate this cohort from other Latin American cohorts and reflect the specific characteristics of a specialized private center.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"46 1","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cutaneous manifestations in patients with inflammatory bowel disease]. 【炎症性肠病患者的皮肤表现】。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Daniel Barquero-Orias, Ariana Ramirez-Zumbado, Keren Castro-López, Kenneth Ernest-Suárez

引用次数: 0

[Beyond the gut: articular involvement in inflammatory bowel disease]. [超越肠道：炎症性肠病的关节参与]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Viviana Parra Izquierdo, Juan Sebastián Frías-Ordoñez, María Consuelo Romero

{"title":"[Beyond the gut: articular involvement in inflammatory bowel disease].","authors":"Viviana Parra Izquierdo, Juan Sebastián Frías-Ordoñez, María Consuelo Romero","doi":"","DOIUrl":"","url":null,"abstract":"Extraintestinal manifestations (EIMs) are a key component of the clinical burden of inflammatory bowel disease (IBD), with articular involvement being the most common and one of the main contributors to functional impairment and reduced quality of life. Despite its clinical relevance, its pathogenesis remains incompletely understood. Current evidence supports the existence of a gut-joint axis, involving immune dysregulation, genetic susceptibility, and alterations in the intestinal microbiota. Articular involvement in IBD encompasses a broad spectrum of manifestations, including both peripheral and axial forms, with heterogeneous clinical presentations that may precede, accompany, or occur independently of intestinal activity. This variability contributes to diagnostic delays and under-recognition in clinical practice. In this context, early identification of clinical features and a deeper understanding of the underlying mechanisms are essential to improve diagnostic accuracy and therapeutic strategies. This article aims to provide an updated review of the literature on articular involvement in IBD, integrating recent advances in pathophysiology and highlighting key clinical aspects for its suspicion, diagnosis, and management.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"46 1","pages":"51-57"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality indicators for colonoscopy in Peruvian national hospitals: a multicenter cross-sectional study. 秘鲁国立医院结肠镜检查质量指标：一项多中心横断面研究。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Diego A Leon-Quispe, Patricia Valera-Luján, Edson Gudiel-Palomino, Grecia Claussen-Portocarrero, Luis Yllescas-Estela, Evelyn León Estela, Thessia Varona Luna, Sharon Z C Aldave Chirinos

{"title":"Quality indicators for colonoscopy in Peruvian national hospitals: a multicenter cross-sectional study.","authors":"Diego A Leon-Quispe, Patricia Valera-Luján, Edson Gudiel-Palomino, Grecia Claussen-Portocarrero, Luis Yllescas-Estela, Evelyn León Estela, Thessia Varona Luna, Sharon Z C Aldave Chirinos","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To evaluate colonoscopy quality indicators in Peruvian national public hospitals and to estimate the polyp detection rate (PDR) corresponding to adenoma detection rate (ADR) benchmarks of 25% and 35%.Materials and methods: A multicenter retrospective study was conducted using colonoscopy reports from July 2023 to June 2024. Rates of adequate bowel preparation and cecal intubation, as well as withdrawal time, polypectomy technique, PDR, and ADR were evaluated.Results: A total of 3,758 colonoscopies performed by 63 endoscopists were analyzed. The rate of adequate bowel preparation was 91.1%, and the cecal intubation rate was 95.6%. The withdrawal time was not reported in 75% of procedures without polyp detection. Only 30.2% of polyps measuring 4-9 mm were removed using cold snare polypectomy. The overall PDR was 41.3%, and the overall ADR was 22.8%. The adenoma-to-polyp detection rate quotient was 0.56; a PDR of 62.5% corresponded to an ADR of 35%, and a PDR of 44.7% to an ADR of 25%.Conclusions: Colonoscopy quality in Peruvian national public hospitals showed adequate rates of bowel preparation and cecal intubation but suboptimal ADR values and deficient documentation practices, underscoring the need to implement targeted strategies to improve colonoscopy quality.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"46 1","pages":"34-40"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cholestatic jaundice revealing pylephlebitis associated with mesenteric venous thrombosis]. 胆汁淤积性黄疸显示肾盂炎伴肠系膜静脉血栓形成。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Siomara Aransuzú Chávez-Sánchez, Rubén Hessen Escobar-Montes, Álvaro Bellido-Caparó, Fernando Alonso Mejía-Cordero, Carmen Anita Del Villar-Alarcón, José Antonio Chávez-Peche

引用次数: 0

Access barriers and ethical challenges of therapeutic decision-making in patients with inflammatory bowel disease and prior malignancy: a case series. 炎性肠病和既往恶性肿瘤患者治疗决策的准入障碍和伦理挑战：一个病例系列。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2026-01-01

Larissa Leandro Medeiros, Thales Queiroz Souza, Maria Luiza Cronemberger de Faria, Ricardo Jacarandá de Faria, Zuleica Barrio Bortoli, Ana Carolina Benvindo Lopes, Bruno Augusto Alves Martins, Marcos de Vasconcelos Carneiro, Caio Cardozo Jorge

{"title":"Access barriers and ethical challenges of therapeutic decision-making in patients with inflammatory bowel disease and prior malignancy: a case series.","authors":"Larissa Leandro Medeiros, Thales Queiroz Souza, Maria Luiza Cronemberger de Faria, Ricardo Jacarandá de Faria, Zuleica Barrio Bortoli, Ana Carolina Benvindo Lopes, Bruno Augusto Alves Martins, Marcos de Vasconcelos Carneiro, Caio Cardozo Jorge","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To report a case series of patients with inflammatory bowel diseases and a history of malignancy and to analyze how this condition influenced therapeutic decision-making presents a challenging scenario.Materials and methods: This was a retrospective observational study analyzing 11 patients with inflammatory bowel disease and malignant neoplasms followed at an inflammatory bowel disease outpatient clinic of a university hospital. Clinical, therapeutic, and oncologic findings are reported descriptively based on medical record review.Results: Seven patients (64%) had ulcerative colitis, and six (55%) were female, with a mean age of 47 years. Extra-intestinal neoplasms predominated. Six patients (55%) received advanced therapy near the time of cancer diagnosis; reintroduction was possible in four cases. Judicial action was required for two patients.Conclusions: Clinical decision-making in patients with inflammatory bowel disease and a history of malignancy is an individualized process, based on multidisciplinary discussion, bioethical considerations, and the most reliable available evidence, even in the face of state-imposed logistical obstacles. Continuous updating of Clinical Protocols and Therapeutic Guidelines is essential to ensure equitable access to the most appropriate and non-harmful treatment for this patient group.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"46 1","pages":"14-19"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0