Agustín Virgili, Ignacio Virgili, José María Sanguinetti
{"title":"[Duodeno-cava fistula secondary to metallic foreign body and inferior cava vein thrombosis].","authors":"Agustín Virgili, Ignacio Virgili, José María Sanguinetti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Duodeno-caval fistula (DCF) is an extremely rare entity that can have potentially lethal consequences. It is associated with infectious, neoplastic, traumatic processes, or foreign bodies. We report a case of DCF secondary to the migration of a metallic wire from the duodenum to the inferior vena cava (IVC), accompanied by extensive venous thrombosis. A 48-year-old male with no relevant medical history presented with fever and nonspecific abdominal pain. He was admitted with an initial diagnosis of acute dengue in the context of an ongoing epidemic. Computed tomography revealed a linear metallic foreign body crossing the second portion of the duodenum, penetrating the visceral wall, and lodging within the lumen of the IVC, with air inside and extensive venous thrombosis. Upper digestive video endoscopy (EGD) was performed, with successful extraction of the foreign body. The patient received intravenous antibiotic therapy for 10 days and oral anticoagulation for 6 months. Clinical evolution was favorable, and the patient recovered without complications. DCF due to a foreign body is extremely rare. Endoscopic management can be successful in selected cases, avoiding invasive surgical procedures.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 4","pages":"419-421"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harold Benites-Goñi, Diego Berrospi-Castillo, Paulo Bardalez-Cruz, Bryan Medina-Morales, Jairo Asencios-Cusihuallpa, Luis Marin-Calderón
{"title":"[Safety and efficacy of underwater endoscopic mucosal resection for non-pedunculated colorectal polyps larger than 10 mm].","authors":"Harold Benites-Goñi, Diego Berrospi-Castillo, Paulo Bardalez-Cruz, Bryan Medina-Morales, Jairo Asencios-Cusihuallpa, Luis Marin-Calderón","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Colorectal cancer (CRC) is one of the leading causes of cancer-related death in Peru. Endoscopic resection of colorectal polyps has been shown to reduce the incidence and mortality of CRC. Underwater endoscopic mucosal resection (UEMR) has emerged as a safe and effective technique for the management of non-pedunculated polyps.</p><p><strong>Objectives: </strong>To evaluate the efficacy and safety of UEMR for non-pedunculated colorectal polyps larger than 10 mm in a high-complexity hospital in Lima, Peru.</p><p><strong>Materials and methods: </strong>Observational, retrospective, and descriptive study of patients aged ≥18 years who underwent UEMR between January and December 2023. En bloc resection, R0 resection, recurrence, and complication rates were analyzed. Clinical, endoscopic, and histopathological data were collected.</p><p><strong>Results: </strong>A total of 119 UEMRs were performed in 91 patients, with a median age of 72 years. 60.5% of lesions were located in the right colon, and most measured between 10-19 mm. The en bloc resection rate was 80%, and the R0 resection rate was 78%. The complication rate was 15%, including one perforation and two delayed bleeding events. Most complications occurred in the right colon. Recurrence was 3.1%, observed only in piecemeal resections. Histopathological findings included low-grade (47.9%) and high-grade (28.6%) adenomas, as well as 7 carcinomas (5.8%).</p><p><strong>Conclusions: </strong>UEMR is an effective and safe technique for the treatment of non-pedunculated colorectal polyps larger than 10 mm, particularly for lesions ≤20 mm. Its advantages include a high en bloc resection rate, low complication risk, and low cost.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"265-272"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Muñoz-Urribarri, Kelly Angulo Arze, Carolina Llerena Luna, Diego Chipa Guillen, Cristina Ferrando Montoya, Jonathan Dávila Briones, Alex Delgado Godos, Michael Quispe Huarcaya, David Quiñonez Saif, Jackelyn Muñoz Sosa
{"title":"[Prevalence of Helicobacter pylori diagnosed by endoscopy in children with gastrointestinal symptoms treated at a tertiary-level hospital in Lima, Peru].","authors":"Ana Muñoz-Urribarri, Kelly Angulo Arze, Carolina Llerena Luna, Diego Chipa Guillen, Cristina Ferrando Montoya, Jonathan Dávila Briones, Alex Delgado Godos, Michael Quispe Huarcaya, David Quiñonez Saif, Jackelyn Muñoz Sosa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Helicobacter pylori - is an infection acquired in childhood, especially in countries with high prevalence such as Peru, however, the number of studies in this population is scarce, so the need to describe its prevalence and the need for treatment is evident.</p><p><strong>Objectives: </strong>To determine, through endoscopy and biopsy, the current prevalence of this infection in Peruvian children with digestive complaints who attend the Hospital Nacional Edgardo Rebagliati Martins.</p><p><strong>Materials and methods: </strong>A retrospective descriptive study was conducted with 242 patients aged 0 to 14 years, using the electronic medical records from the hospital system.</p><p><strong>Results: </strong>The prevalence of Helicobacter pylori was 27.2%. There were no characteristic symptoms in the positive versus negative- group. The most relevant endoscopic findings in the positive group were a high frequency of antral nodular gastritis (72.1% vs. 9.8%, p<0.001) and a lower prevalence of endoscopic esophagitis (13.1% vs. 23.6%, p<0.001). Otherwise, histopathological analysis revealed a higher presence of lymphoid follicles (24.5% vs. 4.5%, p<0.001), while chronic inflammation was lower (54% vs. 87.5%, p<0.001).</p><p><strong>Conclusions: </strong>It is concluded that the histopathological findings associated with positive Helicobacter pyloriare characteristic in this group and prevalence of this bacteria in Peruvian children seen in a pediatric gastroenterology unit is apparently lower than similar previous studies. This highlights the need for further research to evaluate its relationship with the possibility of antimicrobial resistance and the rising of immune-mediated diseases.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"243-249"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Darío Portillo-Miño, Sandra Cifuentes, Javier Morales, Melissa Bastidas, William Otero, Paulo Pimentel de Assumpção, Gonzalo Latorre, Megan Neuman, Arnoldo Riquelme
{"title":"Gastric remnant cancer: a comprehensive narrative review from carcinogenesis to treatment.","authors":"José Darío Portillo-Miño, Sandra Cifuentes, Javier Morales, Melissa Bastidas, William Otero, Paulo Pimentel de Assumpção, Gonzalo Latorre, Megan Neuman, Arnoldo Riquelme","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Gastric remnant cancer is cancer secondary to partial gastrectomy after five years. Peculiarities due to the gastrectomy status may influence this type of GC. Modifications in the gastric microbiome, luminal pH, dietary habits, increased bile reflux, and Epstein-Barr virus infection, together with the traditional GC risk factors, cooperate to increase the risk of cancer in the remnant stomach. H. pylori infection has been widely associated with GC, and its role in the pathogenesis of the remnant stomach, as well as the preventive effect of its eradication after gastrectomy, are issues of great scientific interest. Bariatric surgery is another condition potentially related to increased GC risk and challenges to its diagnosis. In this scenario, this article aims to review the current evidence of the fundamental aspects involved in developing the gastric remnant cancer.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"282-294"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[How to publish a scientific article in a Journal?]","authors":"Hugo Guillermo Cedrón Cheng","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"227-228"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Barrera, Pedro Acuña, María Macarena Medina, José Tomás Peña, Javier Uribe, Javiera Torres, Chloe Jacomet, Gonzalo Latorre
{"title":"[Endoscopic findings in microscopic colitis: a diagnostic challenge in clinical practice].","authors":"Manuel Barrera, Pedro Acuña, María Macarena Medina, José Tomás Peña, Javier Uribe, Javiera Torres, Chloe Jacomet, Gonzalo Latorre","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Microscopic colitis (MC) is a chronic inflammatory bowel disease characterized by watery diarrhea and a macroscopically normal-appearing colonic mucosa on colonoscopy. It is classified into lymphocytic colitis (LC) and collagenous colitis (CC). Its incidence has increased in developed countries, but data from Latin America remain limited. We present the case of a 65-year-old woman with fibromyalgia and recent use of duloxetine, who presented with chronic diarrhea. Colonoscopy revealed edematous mucosa with loss of vascular transparency, deep furrows with a cobblestone-like appearance, and an open dot-like surface pattern. Histopathological analysis confirmed a diagnosis of LC. After discontinuing duloxetine, the diarrhea resolved spontaneously without the need for corticosteroids. Although MC has traditionally been described as presenting with a normal-appearing colonic mucosa, studies have reported subtle and nonspecific findings such as edema, erythema, and vascular pattern abnormalities. Detection of these findings can be improved through the use of virtual chromoendoscopy and high-definition equipment. Recognizing these patterns may enhance biopsy targeting and increase the detection of this condition, especially in the evaluation of chronic diarrhea. However, endoscopic findings must be differentiated from other conditions, such as inflammatory bowel disease or ischemic colitis.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"307-311"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gustavo de Nardi Marçal, Rodrigo Bremer Nones, Eron Fábio Miranda, Fernanda da Silva Barbosa Baraúna, Daniela Oliveira Magro, Paulo Gustavo Kotze
{"title":"Serum infliximab concentrations and body mass index in patients with inflammatory bowel disease.","authors":"Gustavo de Nardi Marçal, Rodrigo Bremer Nones, Eron Fábio Miranda, Fernanda da Silva Barbosa Baraúna, Daniela Oliveira Magro, Paulo Gustavo Kotze","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic conditions associated with healthcare burdens. Advanced therapies, such as infliximab (IFX), have improved disease outcomes. However, the role of body mass index (BMI) in influencing IFX serum concentrations and treatment response remains unclear.</p><p><strong>Objective: </strong>This study aimed to evaluate the association between BMI and IFX serum concentrations during different disease activity phases.</p><p><strong>Materials and methods: </strong>This cross-sectional observational report categorized patients into eutrophic (BMI < 24.9kg/m²) and overweight/obese (BMI ≥ 25 kg/m²) groups. Serum IFX concentrations were measured, and disease activity was assessed using clinical, laboratory, endoscopic, and/or radiologic criteria.</p><p><strong>Results: </strong>The analysis included 102 patients (80 with CD, 22 with UC). The median serum IFX concentration in eutrophic CD patients was 3.84 μg/mL (1.66-8.82), while in overweight/obese patients was 6.00 μg/mL (1.90-10.34), with no significant difference (p=0.353). Among the 22 patients with UC, the median serum IFX concentration in eutrophic patients was 6.28μg/mL (0.860-13.66), compared to 4.23 μg/mL (2.33-12.91) in overweight/obese patients, with no significant difference (p = 0.920). No differences were found in IFX concentrations between patients in remission or active disease.</p><p><strong>Conclusions: </strong>this study did not confirm that BMI influences IFX concentrations. More studies are needed to explore the impact of BMI on IFX pharmacokinetics and therapeutic efficacy.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"229-235"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enrique Evans Rodríguez, Luis Carlos Araya Acero, Jorge Eduardo Vargas Madriga
{"title":"[Endoscopic ultrasound-guided hepatogastrostomy (EUS-HGS) as a rescue biliary drainage strategy: experience in a tertiary care hospital in Costa Rica].","authors":"Enrique Evans Rodríguez, Luis Carlos Araya Acero, Jorge Eduardo Vargas Madriga","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Endoscopic retrograde cholangiopancreatography (ERCP) is the standard treatment for biliary drainage, but it may fail in patients with advanced malignant obstruction. In such cases, endoscopic ultrasound-guided hepatogastrostomy (EUS-HGS) has emerged as an effective therapeutic alternative. This retrospective study describes the experience of Hospital San Juan de Dios, Costa Rica, with EUS-HGS as a rescue drainage strategy after failed ERCP.</p><p><strong>Objective: </strong>To describe the institutional experience with EUS-HGS as a biliary drainage technique in patients with unresectable malignant obstruction and failed ERCP, evaluating its technical feasibility, clinical efficacy, and safety in a high-complexity public center.</p><p><strong>Materials and methods: </strong>Twenty consecutive patients treated with EUS-HGS between April 2023 and March 2024 were included. Clinical success was defined as a ≥50% reduction in total bilirubin at 30 days. Adverse events, procedure time, and technical success were evaluated.</p><p><strong>Results: </strong>Technical success was achieved in 100% of cases (20/20). Nineteen patients (95%) reached clinical success. The mean procedure time was 18 minutes. No major complications or mortality were reported. Three patients (15%) presented mild adverse events (abdominal pain and minimal bleeding).</p><p><strong>Conclusion: </strong>EUS-HGS proved to be a safe, effective, and reproducible technique in patients with failed ERCP. The institutional experience supports its use in public centers with trained personnel, strengthening its role in the management of complex malignant biliary obstruction.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"250-254"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Martin Padilla-Machaca, Sergio Padilla Gonzales, Maria Grazia Venturelli Romero, Maria Cecilia Cabrera Cabrejos
{"title":"[Variceal gastrointestinal bleeding: epidemiology, pathogenesis, management and prophylaxis].","authors":"P Martin Padilla-Machaca, Sergio Padilla Gonzales, Maria Grazia Venturelli Romero, Maria Cecilia Cabrera Cabrejos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Variceal gastrointestinal bleeding is one of the main complications of portal hypertension in patients with cirrhosis. It affects those with decompensated cirrhosis, and its occurrence marks a turning point in the progression of liver disease. Despite therapeutic advances, challenges remain in comprehensive management, particularly in resource-limited settings. Treatment aims to control active bleeding, prevent early rebleeding, and reduce mortality. This review summarizes recent evidence on the pathophysiology, diagnosis, and updated management of variceal gastrointestinal bleeding, including emerging strategies such as early vasoactive therapy, rational use of transfusions, antibiotic prophylaxis, and the key role of timely endoscopy. It also highlights the importance of identifying clinically significant portal hypertension to prevent complications and improve clinical outcomes.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"273-281"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renatto Ruiz-Cortez, Mirko Damas-Valera, Grecia Galvez-Nino, Frine Samalvides-Cuba, Carlos Barreda-Costa, Jorge Espinoza-Ríos
{"title":"[Helicobacter pylori eradication and associated factors: dual therapy versus standard triple therapy in Lima, Peru].","authors":"Renatto Ruiz-Cortez, Mirko Damas-Valera, Grecia Galvez-Nino, Frine Samalvides-Cuba, Carlos Barreda-Costa, Jorge Espinoza-Ríos","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Helicobacter pylori (H. pylori) infection is the most important risk factor for gastric cancer development. Dual therapy can achieve higher eradication rates than standard triple therapy, and the factors associated with lower eradication rates have not been fully studied. The objective of our study was to evaluate the H. pylori eradication rate and its associated factors using dual therapy versus standard triple therapy.</p><p><strong>Materials and methods: </strong>This retrospective cohort study included 1,506 patients with H. pylori infection who received dual therapy or standard triple therapy. Eradication was confirmed with urea breath test. Chi-square (χ) test was used to analyze categorical variables, and relative risk (RR) was used to assess associations between eradication rates and clinical variables.</p><p><strong>Results: </strong>Eradication was higher with dual therapy, with 84.58% (384/454) versus 73.86% (777/1052) with standard triple therapy (p<0.001). The overall eradication rate with esomeprazole was 82.13% (648/789), followed by lansoprazole at 73.70% (213/289) and pantoprazole at 70.09% (300/428) (p<0.001). No significant differences were found regarding comorbidities such as diabetes, hypertension, or dyslipidemia.</p><p><strong>Conclusions: </strong>The H. pylori eradication rate with dual therapy was superior to standard triple therapy. The proton pump inhibitor with the highest eradication rate was esomeprazole. There were no significant differences in eradication according to sex, age, or comorbidities.</p>","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"236-242"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}