Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru最新文献_第5页

[Real-world experience with upadacitinib induction for inflammatory bowel disease in Colombia: uparecol-induction]. [在哥伦比亚，upadacitinib诱导炎症性肠病的实际经验：uparecol诱导]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-07-01

Viviana Parra-Izquierdo, Juan Sebastián Frías-Ordoñez, Fabio Leonel Gil-Parada, William Otero-Regino, Jonathan Barreto Perez, German Manuel Tovar Fierro, Fabian Eduardo Puentes-Manosalva, Pedro Eduardo Cuervo Pico, María Teresa Galiano, Javier Riveros, Alvaro Andrés Gomez-Venegas, Carlos Andrés Medrano Almanza, Daniel Perea, Manuel Ballesteros, Carlos Augusto Cuadros Mendoza, Cristian Florez-Sarmiento

{"title":"[Real-world experience with upadacitinib induction for inflammatory bowel disease in Colombia: uparecol-induction].","authors":"Viviana Parra-Izquierdo, Juan Sebastián Frías-Ordoñez, Fabio Leonel Gil-Parada, William Otero-Regino, Jonathan Barreto Perez, German Manuel Tovar Fierro, Fabian Eduardo Puentes-Manosalva, Pedro Eduardo Cuervo Pico, María Teresa Galiano, Javier Riveros, Alvaro Andrés Gomez-Venegas, Carlos Andrés Medrano Almanza, Daniel Perea, Manuel Ballesteros, Carlos Augusto Cuadros Mendoza, Cristian Florez-Sarmiento","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: There are no studies on the efficacy and safety of upadacitinib for Inflammatory Bowel Disease (IBD) in Latin America. This study aims to describe its efficacy and safety during the induction phase in patients with moderate-to-severe IBD.Materials and methods: A multicenter observational descriptive study in IBD patients who received upadacitinib during the induction phase between July 2024 and January 2025.Results: A total of 26 patients were included, 53.8% female, with a mean age of 41.5 years (range 18.1-70.4; SD 17.5). Ulcerative colitis (UC) was present in 61.5% and Crohn's disease (CD) in 38.5%, with a mean disease duration of 6.4 years. In UC, 62.5% achieved clinical response, 37.5% clinical remission, and 56.3% biochemical remission. In CD, 70% achieved clinical response, 20% clinical remission, and 50% biochemical remission. Nine of 16 UC patients (56.3%) and 3 of 10 CD patients (30%) achieved clinical remission of stool frequency and abdominal pain. In UC, there was a trend towards greater efficacy in urgency (OR 2.87; 95% CI: 0.53-18.25; p=0.19). Among 12 patients with extraintestinal manifestations (EIMs), 75% achieved remission. Adverse events were reported in 5 patients (19.3%): three cases of acne, one mild infection, and one severe infection.Conclusions: This first Latin American study on upadacitinib in IBD demonstrates its efficacy and safety in patients with moderate-to-severe disease activity.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"255-264"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Endoscopic ultrasound-guided gastro-enteric anastomosis for malignant gastric outlet obstruction: Initial experience in an endoscopic center in Lima-Peru]. 【超声内镜引导下胃-肠吻合治疗恶性胃出口梗阻：利马-秘鲁内镜中心的初步经验】。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-07-01

Juan Antonio Chirinos-Vega, Oscar Eduardo Ponce de León Molina

引用次数: 0

[Rescue of a recurrence of rectal adenoma using the endoscopic intermuscular dissection technique]. 应用内窥镜肌间解剖技术抢救直肠腺瘤复发1例。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-07-01

Gonzalo Latorre, Javier Perez-Valenzuela, Felipe Silva, Antonio Pausin, Antonio Mercandino, José Tomás Peña, Javiera Torres, Felipe Bellolio, Andrés Donoso

{"title":"[Rescue of a recurrence of rectal adenoma using the endoscopic intermuscular dissection technique].","authors":"Gonzalo Latorre, Javier Perez-Valenzuela, Felipe Silva, Antonio Pausin, Antonio Mercandino, José Tomás Peña, Javiera Torres, Felipe Bellolio, Andrés Donoso","doi":"","DOIUrl":"","url":null,"abstract":"Endoscopic intermuscular dissection (EID) emerges as an alternative for the treatment of patients with rectal lesions with suspected deep invasion or with extensive fibrosis which are not candidates for endoscopic submucosal dissection (ESD). In EID the dissection is performed between the inner (circular) and outer (longitudinal) layers of the muscularis propia. We present the case of a patient successfully treated with EID technique. 54-year-old female patient with a history sessile adenomatous lesion of the rectum of approximately 40 mm resected with conventional endoscopic mucosal resection technique. She presented a recurrence of the lesion on the prior resection scar. EID was performed on the scar of prior endoscopic resection, accessing and exposing the intermuscular plane. En bloc resection of the lesion was achieved with negative histological lateral and deep margins, fulfilling criteria for curative resection. Endoscopic resection techniques offer advantages over radical proctectomy, allowing preservation of anorectal function with lower morbidity and mortality. EID has shown effectiveness and safety in prospective studies and case report when ESD is not feasible due to technical limitations. However, further studies are required to evaluate the long-term efficacy and its comparison with other resection techniques.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"295-299"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Abdominal tuberculosis in the era of inflammatory bowel disease: the diagnostic challenge of a forgotten disease]. 【炎症性肠病时代的腹部结核：一种被遗忘疾病的诊断挑战】。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-07-01

Gilberto Jaramillo Trujillo, Hernando Marulanda Fernández, Juan Sebastián Frías Ordoñez, Jean Sebastián Barrero, William Otero Regino

{"title":"[Abdominal tuberculosis in the era of inflammatory bowel disease: the diagnostic challenge of a forgotten disease].","authors":"Gilberto Jaramillo Trujillo, Hernando Marulanda Fernández, Juan Sebastián Frías Ordoñez, Jean Sebastián Barrero, William Otero Regino","doi":"","DOIUrl":"","url":null,"abstract":"Abdominal tuberculosis (ATB) represents a considerable diagnostic challenge due to its nonspecific clinical presentation and resemblance to conditions such as inflammatory bowel disease (IBD) or digestive neoplasms. In endemic regions, timely recognition is crucial to avoid inappropriate immunosuppression and therapeutic delays. Case description: Four immunocompetent adults with ATB were treated at a tertiary-level hospital in southwestern Colombia between January 2023 and May 2025. All presented with chronic diarrhea, abdominal pain, fever, and weight loss. The initial suspicion was Crohn's disease or infectious colitis. Imaging revealed ileocecal and colonic involvement; endoscopy showed ulcerated lesions, and histology demonstrated granulomatous inflammation with caseous necrosis. Tissue PCR confirmed Mycobacterium tuberculosis infection. In three cases, pulmonary tuberculosis coexisted. All patients received standard antituberculous therapy with favorable outcomes. This series highlights the ability of ATB to mimic IBD and the need to maintain a high index of suspicion in endemic contexts. An integrated approach combining clinical, endoscopic, histological, and molecular evaluation is essential for accurate diagnosis and timely treatment.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"322-330"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Gastro-gastric fistula following gastric bypass: a case report]. 胃分流术后胃瘘1例。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-07-01

Lázaro Antonio Arango Molano, Andrés Sánchez Gil, Herney Solarte Pineda, Adhara Marina Estrada Torres

引用次数: 0

[Peroral endoscopic myotomy as first-line treatment in pediatric esophageal achalasia: a case report and literature review]. [经口内窥镜下肌切开术作为儿童食管贲门失弛缓症的一线治疗：1例报告及文献复习]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-07-01

Carlos Augusto Cuadros Mendoza, Lizeth Karina Lozano Rivera, Juan Javier Acevedo Mantilla, Viviana Parra Izquierdo, Johon Francisco Garcés Camacho

{"title":"[Peroral endoscopic myotomy as first-line treatment in pediatric esophageal achalasia: a case report and literature review].","authors":"Carlos Augusto Cuadros Mendoza, Lizeth Karina Lozano Rivera, Juan Javier Acevedo Mantilla, Viviana Parra Izquierdo, Johon Francisco Garcés Camacho","doi":"","DOIUrl":"","url":null,"abstract":"Esophageal achalasia (EA) is a primary motility disorder characterized by the inability of the lower esophageal sphincter (LES) to relax properly. It is a rare condition in the pediatric population and therefore requires a high index of clinical suspicion. Delayed diagnosis can lead to significant morbidity. Treatment is aimed at reducing LES pressure, which helps relieve symptoms. We present the case of a 10-year-old male patient, with a history of IgE-mediated food allergy to dairy and peanuts, born and raised in the Turks and Caicos Islands, who was referred to our institution with a six-month history of progressive dysphagia for solids, postprandial vomiting, and significant weight loss. A barium esophagram revealed severe dilation of the esophageal body, with a distal esophagus showing the classic \"bird's beak\" appearance. High-resolution esophageal manometry confirmed the diagnosis of type I EA. The patient underwent a peroral endoscopic myotomy (POEM), an innovative procedure that has proven to be effective, safe, and durable in the management of pediatric achalasia. This technique is available in experienced centers with specialized equipment and may represent a first-line treatment option in children with esophageal achalasia. To our knowledge, this is the youngest patient reported in Colombia with esophageal achalasia who achieved a successful clinical outcome following POEM.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 3","pages":"312-317"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chromoendoscopy innovation: Could purple corn solution be a potential natural contrast agent for detecting colonic lesions? 色内窥镜的创新：紫玉米溶液是否可能成为检测结肠病变的天然造影剂？

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-04-01

Gustavo Kishimoto, Tamy Yamamoto

引用次数: 0

[Esophageal metastasis from primary colon adenocarcinoma: presentation of an unusual clinical case]. 原发性结肠腺癌食管转移一例罕见的临床表现。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-04-01

Fabian Eduardo Puentes Manosalva, Lázaro Arango Molano, Santiago Salazar Ochoa, Herney Solarte Pineda, Gian Núñez Rojas

引用次数: 0

[From the stethoscope to ultrasound: POCUS (point-of-care ultrasound) in gastroenterology and hepatology]. [从听诊器到超声：POCUS （point-of-care ultrasound）在胃肠病学和肝病学中的应用]。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-04-01

Hugo Guillermo Cedrón Cheng

引用次数: 0

[Diagnostic strategy following failed colonoscopy: endoscopic ultrasound-guided fine needle biopsy in colon cancer]. 【结肠镜检查失败后的诊断策略：内镜下超声引导的结肠癌细针活检】。

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru Pub Date : 2025-04-01

Calixto Duarte-Chang, Julio Zúñiga Cisneros, Ramiro Da Silva Rodriguez

{"title":"[Diagnostic strategy following failed colonoscopy: endoscopic ultrasound-guided fine needle biopsy in colon cancer].","authors":"Calixto Duarte-Chang, Julio Zúñiga Cisneros, Ramiro Da Silva Rodriguez","doi":"","DOIUrl":"","url":null,"abstract":"Endoscopic ultrasound (EUS)-guided sampling is a safe and reliable method for obtaining pathological results of gastrointestinal and adjacent gastrointestinal lesions. Some colon lesions are located in the muscular layer or even in the serosa beneath the mucosa, so conventional colonoscopy with forceps biopsy is often negative. In patients with colon cancer, forceps biopsy during colonoscopy is the current standard diagnostic modality. However, there are cases that are difficult to confirm with forceps biopsy, such as stenosing tumors, or those originating from deep layers. Endoscopic ultrasound (EUS)-guided fine needle biopsy (FNB) is a useful alternative for diagnosis in these cases. We present the successful case of a 62-year-old male with a history of progressive weight loss and a colonic mass at the splenic flexure, whose colonoscopy was unsuccessful, therefore a FNB puncture by EUS was performed, via transgastric route, reaching a histological diagnosis of colon adenocarcinoma. This case highlights the feasibility of FNB by EUS in the acquisition of colonic lesions through the stomach in cases of inconclusive colonoscopy.","PeriodicalId":35807,"journal":{"name":"Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru","volume":"45 2","pages":"180-183"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0