Inês Dias, Pedro Fonseca, D. Furtado, I. Figueira, Paulo Franco, Vanda Cláudio, Helena Antunes, J. Fragata, C. Quaresma, Carla Quintão
{"title":"Development of a Parameter Calculator in Cardiovascular Perfusion - BioMEP as a Tool for the Register of Physiological Parameters","authors":"Inês Dias, Pedro Fonseca, D. Furtado, I. Figueira, Paulo Franco, Vanda Cláudio, Helena Antunes, J. Fragata, C. Quaresma, Carla Quintão","doi":"10.5220/0006723502540257","DOIUrl":"https://doi.org/10.5220/0006723502540257","url":null,"abstract":"Technology has played an increasingly important role in the health sector, with new devices allowing for better real-time monitoring of patients’ biosignals. Among those, the ones developed with perfusion in mind are extremely useful, during cardiothoracic surgery, since they provide detailed information about the vital signs of the patient. However, doctors and technicians have often to calculate several physiological parameters, which help them make clinical decision during such surgical interventions. In this context, the authors present a software tool – BioMEP: Perfusion Calculator Application, built in a partnership between the Department of Cardiothoracic Surgery of Santa Marta Hospital and the Department of Physics of the Faculty of Sciences and Technology of the NOVA University of Lisbon, and which fulfils the needs of the surgical team. BioMEP Perfusion Calculator Application is a safe, intuitive and user-friendly tool that incorporates and integrates department-specific perfusion parameters and calculations, in a single platform, and allows for higher intervention efficiency, while minimizing the errors of the required calculation, with the concomitant improvement in patient safety.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125557340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elisabeth Borges, M. Sequeira, A. Cortez, H. Pereira, T. Pereira, V. Almeida, T. Vasconcelos, I. Duarte, N. Nazaré, J. Cardoso, C. Correia
{"title":"Bioimpedance Parameter as a Risk Factor to Assess Pine Decay - An Innovative Approach to the Diagnosis of Plant Diseases","authors":"Elisabeth Borges, M. Sequeira, A. Cortez, H. Pereira, T. Pereira, V. Almeida, T. Vasconcelos, I. Duarte, N. Nazaré, J. Cardoso, C. Correia","doi":"10.5220/0004230500350046","DOIUrl":"https://doi.org/10.5220/0004230500350046","url":null,"abstract":"Electrical impedance spectroscopy, EIS, has been proving efficacy and utility in a wide range of areas, from the characterization of biological tissues to living organisms. Several commercial solutions, with high precision and resolution, are available. Nonetheless, the typical equipments are expensive, unfeasible for in vivo and in field applications and unspecific for concrete applications. These features, together with the lately demands in the vegetal field, fundament this work. Actually, the fast spread of asymptomatic forest diseases, with no cure available to date, such as the pinewood disease, PWD, constitute a problem of economical and forestall huge proportions. Herein is proposed a portable EIS system, for biological applications, able to perform AC current or voltage scans within a selectable frequency range. The procedure and the results obtained for a population of 24 young pine trees (Pinus pinaster Aiton) are also presented. Pine trees were kept in a controlled environment and were inoculated with the nematode (Bursaphelenchus xylophilus Nickle), that causes the PWD, and also with bark beetles (Tomicus destruens Wollaston). Some degree of discrimination between different physiological states was achieved. These results may constitute a first innovative approach to the diagnosis of such types of diseases.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134626514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hardware Implementation for Edge Detection in cDNA Microarray Images","authors":"B. Belean, M. Borda, A. Fazakas","doi":"10.5220/0001536403590363","DOIUrl":"https://doi.org/10.5220/0001536403590363","url":null,"abstract":"The present paper proposes hardware implementation strategies for cDNA microarray image processing in order to overcome the main disadvantage introduced by the existing computational tools, the increased processing time. A hardware implementation of the Canny edge detection algorithm for microarray spots is described. The implementation takes advantage of spatial and temporal parallelism offered by FPGA technology. Results of the hardware implementation which prove time and cost efficiency are presented.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131258555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Yamasaki, H. Nakazawa, N. Misawa, M. Ishida, K. Sawada
{"title":"Proposal for a Filterless Fluorescence Sensor for SNP Genotyping","authors":"K. Yamasaki, H. Nakazawa, N. Misawa, M. Ishida, K. Sawada","doi":"10.5220/0003774201850189","DOIUrl":"https://doi.org/10.5220/0003774201850189","url":null,"abstract":"This study describes a biosensor for single nucleotide polymorphism (SNP) genotyping based on the filterless fluorescence detection methods. The filterless fluorescence sensor is able to distinguish lights with more than two different wavelengths without optical filters, mirrors, and gratings. From the final results, we observed that emission lights form the “fluorescein isothiocyanate (i.e., FITC)” and the “sulforhodamine 101 acid chloride (i.e., Texas Red)”, which are kinds of fluorescent dyes commonly used in SNP genotyping, were detected with less interference using the filterless fluorescence sensor. Thus, our approach is effective for SNP genotyping with low cost and high portability.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124300675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
You-Lin Wu, Po-Yen Hsu, Chung-Ping Hsu, Wen-Cheng Liu
{"title":"Electrical Characterization of Sequence-specific Label-free DNA by using Polysilicon Wire","authors":"You-Lin Wu, Po-Yen Hsu, Chung-Ping Hsu, Wen-Cheng Liu","doi":"10.5220/0002712601700173","DOIUrl":"https://doi.org/10.5220/0002712601700173","url":null,"abstract":"In this paper we report the electrical measurement of sequence-specific and label-free deoxyribonucleic acid (DNA) by using poly-silicon (poly-Si) wire. Four single-strained (ss) DNA bases, adenine (A), thymine (T), cytosine (C) and guanines (G), as well as double-stranded (ds) DNA sequences, ds(A-T) and ds(C-G), with different lengths and concentrations were dropped onto the poly-Si wire surface, and currents flowing through the poly-Si wire channel were determined. It is found that the amount change of the channel current ΔI for ssDNAs with fixed length and fixed concentration is that T > C > G > A. For dsDNA sequence, we observe that ds(A-T) has higher ΔI than does ds(C-G). We also prove that single base change in ssDNA is feasible by using the poly-Si wire sensor.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124932097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Mattei, G. Calcagnini, M. Triventi, F. Censi, P. Bartolini
{"title":"MRI-induced SAR on Pacemaker Leads - Numerical Simulations on Three Human Phantoms","authors":"E. Mattei, G. Calcagnini, M. Triventi, F. Censi, P. Bartolini","doi":"10.5220/0003131501350139","DOIUrl":"https://doi.org/10.5220/0003131501350139","url":null,"abstract":"Numerical simulations were performed to evaluate the Specific Absorption Rate (SAR) induced at the tip of a pacemaker (PM) implant by the 64 MHz radiofrequency (RF) field used in 1.5T Magnetic Resonance Imaging (MRI) procedures. The analysis was performed by using a commercial FDTD software (SEMCAD X, SPEAG, Switzerland) and aimed at the evaluation of the impact that the patient ‘s morphology has on the induced local SAR at the implant tip. In particular three human phantoms were studied: a 34-year old man model, a 26-year old woman, and a 6-year old boy. The three phantoms reproduce more than 70 tissues of the human body with a resolution of 1 mm. Inside each phantoms, realistic implant configurations were modelled, considering both left and right pectoral implants, and atrial and ventricular stimulations. The local SAR values at the lead tip was compared for the three phantoms and sensible differences were observed: with a RF excitation set to produce an whole-body average SAR of 2 W/kg without any implants, local SAR values ranged from 641W/kg (woman model – right ventricular implant) to 3 W/kg (boy model – left atrium implant). We also observed that, in general, ventricular implants showed a higher SAR compared to atrial ones, as well as right pectoral implants compared to left ones. However, not always a higher implant area or a longer lead path implied higher SAR at the tip, indicating the coupling mechanisms between the implant and the RF field are likely to be more complex that the only area-dependent induction law.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129210309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Á. Marco, Héctor J. Gracia, Ángel Asensio, Carlos Guallar, J. I. Artigas, Roberto Casas
{"title":"Synchronization Issues in Surgical Training","authors":"Á. Marco, Héctor J. Gracia, Ángel Asensio, Carlos Guallar, J. I. Artigas, Roberto Casas","doi":"10.5220/0001052000820086","DOIUrl":"https://doi.org/10.5220/0001052000820086","url":null,"abstract":"Surgical training systems allow novel surgeons to acquire the required skills to successfully carry out an operation without harming a real patient. These systems emulate the situation of a real operation, replicating the information gathered by sensors, movements of the surgeon, patient response, etc. All this information must be synchronized to provide an experience to the novel surgeon as closest to reality as possible. A special case of information synchronization is when using video images from the operation. In this paper, we analyze these synchronization issues —video, movements, sensors, etc. — and show a particular case that bring all together: an endoscopic video-surgery learning system.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"52 45","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113933350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Towards Personalized Drug Delivery - Preparation of an Encapsulated Multicompartment System","authors":"M. Hadorn, P. E. Hotz","doi":"10.5220/0002691400050012","DOIUrl":"https://doi.org/10.5220/0002691400050012","url":null,"abstract":"Single liposomes and vesicles are successfully utilized as delivery vehicles of pharmaceuticals. However limitations of these unilamellar, single compartments led to the development of encapsulated multicompartment systems that establishes the prospect of multicomponent or multifunctional drug delivery systems. So far compartmentalization is restricted to binary systems. To realize a personalized drug delivery, a programmable linkage of n-entities of different content will be needed. Here we present both a programmable DNA-mediated linkage of three distinct vesicle populations and a novel encapsulation protocol. We discuss how the techniques established in this study might be used in personalized healthcare based on customtailored encapsulated multicompartment vesicular drug delivery systems.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127753939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. J. Fuertes, V. Naranjo, P. González, Á. Bernabeu, M. A. Raya, Javier Sánchez
{"title":"Multivoxel MR Spectroscopy Tool for Brain Cancer Detection in Neuronavigation - Performance","authors":"J. J. Fuertes, V. Naranjo, P. González, Á. Bernabeu, M. A. Raya, Javier Sánchez","doi":"10.5220/0003770501670172","DOIUrl":"https://doi.org/10.5220/0003770501670172","url":null,"abstract":"This work presents a simple and interactive spectroscopic tool to help clinicians for brain cancer detection. Firstly, Magnetic Resonance Spectroscopy (MRS) and Magnetic Resonance Imaging (MRI) are registered to perform brain analysis. After processing the spectroscopic signals with HLSVD method for water suppression, zero-filling and phase-correction algorithms, and apodization functions to improve the signalto-noise ratio (SNR), the metabolite brain maps are generated in order to analyze brain composition. A 3Dspatial distribution of the anatomical and spectroscopic images and how they are registered are presented to facilitate surgery planning. The goal is to generate metabolite brain maps which can be merged with anatomical images in the neuronavigator to provide the surgeon with the exact point where performing the","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122903606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Leong, P. Machado, V. Bexiga, João Paulo Teixeira, I. Teixeira, J. Rego, P. Neves, F. Piedade, P. Lousã, P. Rodrigues, A. Trindade, R. Bugalho, J. Pinheiro, M. Ferreira, J. Varela
{"title":"Data Acquisition Electronics for PET Mammography Imaging","authors":"C. Leong, P. Machado, V. Bexiga, João Paulo Teixeira, I. Teixeira, J. Rego, P. Neves, F. Piedade, P. Lousã, P. Rodrigues, A. Trindade, R. Bugalho, J. Pinheiro, M. Ferreira, J. Varela","doi":"10.5220/0001533001920197","DOIUrl":"https://doi.org/10.5220/0001533001920197","url":null,"abstract":"The purpose of this paper is to present recent developments in the off-detector electronics of a PET (Positron Emission Tomography) system for mammography imaging. In particular, problems and solutions associated with the integration of its Data Acquisition Electronics are targeted. Synchronism is a critical issue in the DAE system. A resynchronization module is proposed to solve communication problems with the internal asynchronous busses with limited degradation of the communication rate, as compared with fully synchronous solutions. Data processing refers to 64 dual-channels, 11bit/channel, at a frequency of 100MHz. The maximum of the DAE output rate is 220 MB/s corresponding to 1 MCoincidence/s. The robustness of the proposed solutions has been validated with software simulation and hardware implementation. Results of test and validation on FPGA, boards and buses are presented.","PeriodicalId":357085,"journal":{"name":"International Conference on Biomedical Electronics and Devices","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131125755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}