2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)最新文献_第2页

Variations of Tendon Tap Force Threshold needed to Evoke Surface Electromyogram Responses after Botulinum Toxin Injection in Chronic Stroke Survivors* 慢性中风幸存者注射肉毒杆菌毒素后，肌腱叩击力阈值的变化需要引起表面肌电反应*

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8717098

B. Afsharipour, Guijin Li, S. Chandra, W. Rymer, N. Suresh

{"title":"Variations of Tendon Tap Force Threshold needed to Evoke Surface Electromyogram Responses after Botulinum Toxin Injection in Chronic Stroke Survivors*","authors":"B. Afsharipour, Guijin Li, S. Chandra, W. Rymer, N. Suresh","doi":"10.1109/NER.2019.8717098","DOIUrl":"https://doi.org/10.1109/NER.2019.8717098","url":null,"abstract":"Botulinum toxin (BT) is a safe and effective neuromuscular blocking agent that is clinically utilized to reduce spasticity after stroke. It is often injected repeatedly at a minimum of 12-week intervals. BT targets the neuromuscular junction and chemically denervates muscle fibers from their corresponding spinal motoneurons (MN). We explored the effect of BT on the amplitude of the smallest tendon tap force (i.e. force threshold) required to elicit a detectable biceps brachii surface electromyogram (sEMG) reflex response. We hypothesized that after BT injection, the force threshold would increase due to a decrease in available efferent activation. Two chronic stroke survivors were recruited. Data were collected before and up to 18 weeks after BT injection. For each subject, sEMG responses were analyzed using high-density sEMG (HDsEMG) recordings, and the threshold tapping forces were identified and mapped for all channels. Unexpectedly, median threshold forces (MTF) decreased post-BT (B01: 30%, B02: 50%). However, after the initial decrease, MTF then increased progressively compared to pre-BT and peaked around 12 weeks (B01: ~4 folds, B02: 50%). This is likely because post-BT, fewer available muscle fibers would require larger tapping forces to evoke detectable sEMG responses. In the last recording session (> 12 weeks), MTF did not return to pre-BT levels, indicating that successive botulinum toxin injections may still be effective if spaced much further apart in time.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130980874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Inkjet-Printed Silver Electrode Array for in-vivo Electrocorticography 用于体内皮质电成像的喷墨印刷银电极阵列

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8717083

Preston D. Donaldson, Leila Ghanbari, Mathew L. Rynes, S. Kodandaramaiah, S. Swisher

{"title":"Inkjet-Printed Silver Electrode Array for in-vivo Electrocorticography","authors":"Preston D. Donaldson, Leila Ghanbari, Mathew L. Rynes, S. Kodandaramaiah, S. Swisher","doi":"10.1109/NER.2019.8717083","DOIUrl":"https://doi.org/10.1109/NER.2019.8717083","url":null,"abstract":"Electrocorticography (ECoG) is an important neuroscientific tool for acquiring information about brain states and mesoscopic neural activity. Additionally, the use of ECoG and the higher resolution technique micro-ECoG (µECoG) show promise in Brain-Machine Interface (BMI) applications for motor and speech prosthetics. Commercially available µECoG arrays made through photolithographic and vapor-deposition processes allow neuroscientists to incorporate µECoG into their studies, however, these electrode arrays can be expensive and do not lend themselves to easy reconfigurability for experiment-specific electrode layouts. Here we show a process for patterning µECoG electrode arrays using inkjet printing on a 50 µm thick PET substrate. With inkjet printing, we achieve electrode active areas with 300 µm diameters and interconnects with a 500 µm pitch. These electrode arrays demonstrate an average impedance of 2.5 kΩ at 100 Hz and were used to record local field potentials from the mouse somatosensory cortex with signal-to-noise ratios between 30-45 dB. Our results demonstrate the feasibility of using inkjet-patterned µECoG electrode arrays in future neuroscientific studies. Furthermore, we expect printed µECoG arrays to be compatible with roll-to-roll processing for high-throughput and low-cost manufacturing, decreasing the cost-barrier for neuroscientists seeking to incorporate customizable µECoG electrode arrays into their experimental design.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"799 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123004570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Direct Stimulation of Bladder Pelvic Nerve using Battery-Free Neural Clip Interface 利用无电池神经夹接口直接刺激膀胱盆腔神经

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8716975

Sanghoon Lee, Hao Wang, W. Y. Peh, N. Thakor, S. Yen, Chengkuo Lee

引用次数: 6

Improving the Performance of SSVEP BCI with Short Response Time by Temporal Alignments Enhanced CCA 通过时序对齐增强型 CCA 提高短响应时间 SSVEP BCI 的性能

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8716985

Aung Aung Phyo Wai, Min-Ho Lee, Seong-Whan Lee, Cuntai Guan

引用次数: 6

Digital Implementation of the Retinal Spiking Neural Network under Light Stimulation 光刺激下视网膜脉冲神经网络的数字化实现

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8716932

Shuangming Yang, Jiang Wang, Bin Deng, Huiyan Li, Y. Che

{"title":"Digital Implementation of the Retinal Spiking Neural Network under Light Stimulation","authors":"Shuangming Yang, Jiang Wang, Bin Deng, Huiyan Li, Y. Che","doi":"10.1109/NER.2019.8716932","DOIUrl":"https://doi.org/10.1109/NER.2019.8716932","url":null,"abstract":"The visual system is one of the most important pathways of obtaining information for human being and other animals. The retina is responsible for initial processing of visual information and transmitting signals to the second processing system by using the spiking activity patterns. This paper implements a retinal spiking neural network based on field-programmable gate array (FPGA), and uses different scopes of light stimulation to stimulate the digital retinal network and induce different spiking activities. The retina neural network contains 96 neurons, which uses Hodgkin-Huxley type neuron model to build neural network using three-layer feedforward neural network structure. The neural network is implemented using Cyclone IV EP4CE115 FPGA, and uses OV7620 camera to obtain external signals. The state machine control the input information of the retina system, and the firing patterns are finally displayed on oscilloscope device. Experimental results show that the proposed digital retinal network can generate the dual-peak response of the retinal ganglion cells. This work is meaningful for the design of the retina prostheses and is helpful for the investigation of the underlying mechanisms of the retinal activities.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126156257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

P300 in the park: feasibility of online data acquisition and integration in a Mobile Brain/Body Imaging setting 园区P300:移动脑/体成像环境下在线数据采集与集成的可行性

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-03-23 DOI: 10.1109/NER.2019.8717141

F. Artoni, Elena Galeasso, S. Micera

{"title":"P300 in the park: feasibility of online data acquisition and integration in a Mobile Brain/Body Imaging setting","authors":"F. Artoni, Elena Galeasso, S. Micera","doi":"10.1109/NER.2019.8717141","DOIUrl":"https://doi.org/10.1109/NER.2019.8717141","url":null,"abstract":"In the last years Mobile Brain/Body Imaging (MoBI) has been increasingly used to study cognition in the real world to give more ecological validity to brain imaging studies currently carried out only inside the lab. To increase portability of the setup and reduce cabling it is possible to perform a unified and real-time synchronized recording of data from multiple sources. However, delays and jitter may impair the quality of the subsequent event-related potential (ERP) analyses. Here we used an online auditory oddball P300 paradigm on one subject to compare the quality of P300 ERPs obtained (i) with online synchronization and alignment and (ii) offline with conventional alignment (synchronization channel) while sitting. We showed that offline and online synchronization strategies provided comparable although slightly different P300 ERP. We also recorded the electroencephalogram (EEG) while walking indoors and outdoors. A decreasing P300 amplitude respectively from sitting to walking indoors and outdoors confirms the dual-task effect on P300. These results show that integrated real-time P300 protocols are feasible but it is also necessary to test delays and quantify the jitter among different signals when developing real-world MoBI applications.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122328491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Myoelectric activity imaging and decoding with multichannel surface EMG for enhanced everyday life applicability 肌电活动成像和解码与多通道表面肌电图增强日常生活的适用性

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-03-23 DOI: 10.1109/NER.2019.8717138

F. Artoni, Stefan Kreipe, S. Micera

{"title":"Myoelectric activity imaging and decoding with multichannel surface EMG for enhanced everyday life applicability","authors":"F. Artoni, Stefan Kreipe, S. Micera","doi":"10.1109/NER.2019.8717138","DOIUrl":"https://doi.org/10.1109/NER.2019.8717138","url":null,"abstract":"Surface electromyography (sEMG) allows to evaluate neurophysiological aspects of movements. The traditional muscle-specific sEMG approach requires considerable expertise to correctly position bipolar derivations over each muscle of interest. This reduces the availability of myoelectric imaging tools for non-professional users in everyday life conditions. High-density EMG (HDsEMG) consists of recording the sEMG via a dense array of electrodes that restricts the imaging surface to a narrow area, thus limiting usability. Here we demonstrate the usability and advantages of a medium-density sEMG (MDsEMG). We recorded the muscle activity of a subject performing repeated arm flexion and extension using both muscle-specific sEMG (4 derivations over the biceps and triceps) and MDsEMG (28 monopolar derivations, positioned around the arm circumference). Grand-average dynamic-time-warped amplitudes showed similar activation patterns for both modalities. However, MDsEMG allowed to extract maps reflecting the spatial activation of muscles at different movement phases (minimum and maximum acceleration). MDsEMG also proved superior in decoding the elbow angle and allowed to map the regions of maximum significance. MDsEMG is a viable alternative to muscle-specific and HD sEMG. It does not require expertise in electrode positioning and is able to cover large surfaces. It thus can pave the way to easier myoelectric imaging in everyday life and more effective rehabilitation treatments.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133807166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroimaging Subjective Labeling Dichotomization and Class Imbalance Alleviation 神经影像学主观标记二分法与班级失衡缓解

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-03-20 DOI: 10.1109/NER.2019.8717181

Badar Almarri, Chun-Hsi Huang

引用次数: 0

Comparison of Common Artifact Rejection Methods applied to Direct Cortical and Peripheral Stimulation in Human ECoG 常用伪影抑制方法在人类脑电图直接皮层和外周刺激中的应用比较

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-03-20 DOI: 10.1109/NER.2019.8716980

K. Sellers, William L. Schuerman, Heather E. Dawes, E. Chang, Matthew K. Leonard

{"title":"Comparison of Common Artifact Rejection Methods applied to Direct Cortical and Peripheral Stimulation in Human ECoG","authors":"K. Sellers, William L. Schuerman, Heather E. Dawes, E. Chang, Matthew K. Leonard","doi":"10.1109/NER.2019.8716980","DOIUrl":"https://doi.org/10.1109/NER.2019.8716980","url":null,"abstract":"Invasive and non-invasive electrical stimulation are increasingly being used for the diagnosis and treatment of neurological disorders, and for characterizing neural circuits involved in a range of behaviors. However, there are substantial challenges in understanding the effects of stimulation on brain activity due to contamination of electrophysiological recordings by electrical stimulation artifacts. Here, we compare the performance of several artifact removal methods on electrocorticographic (ECoG) recordings with simultaneous cortical or peripheral stimulation in humans. We systematically evaluated the effects of stimulation modality, stimulation frequency, and neural recording frequency on the ability to reconstruct neural activity amplitude and phase data. We found that no single method was most effective for all situations, however it was possible to reconstruct key neural data features in every case. The development of optimized artifact removal procedures will facilitate clearer understanding of the biological effects of electrical stimulation and allow for improved therapeutic applications.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129515784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Neural network growth under heterogenous magnetic gradient patterns 异质磁梯度模式下的神经网络生长

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-03-20 DOI: 10.1109/NER.2019.8716902

D. Judge, A. Kunze

{"title":"Neural network growth under heterogenous magnetic gradient patterns","authors":"D. Judge, A. Kunze","doi":"10.1109/NER.2019.8716902","DOIUrl":"https://doi.org/10.1109/NER.2019.8716902","url":null,"abstract":"Magnetic nanoparticles are a versatile tool to modulate calcium signaling, alter intracellular vesicle dynamics, or interfere with gene expression in cerebral neurons through imposing magnetic field gradients on the nanoparticles. However, a lack of understanding of the underlying mechanism, costly experimental magnetic setups and the complexity of magnetic gradient design currently hinder advancements and further integrations into drug studies and clinical translation. Here, we present a robust, low-cost magnetic platform, which is compatible with standard cell culture assays and Petri dishes, in combination with a fully integrated computation of the superimposing magnetic field and force maps. Utilizing the magnetic Petri dish platform, we designed and studied the impact of different magnetic field patterns on force-mediated neurite growth in dissociated primary rodent cortical neurons. We found that neurite growth re-orients strongest within a symmetric bidirectional magnetic gradient pattern without impairing neurite growth. Our magnetic Petri dish platform provides convenient means to extend magnetic force studies into tissue engineering, pharmaceutical, and translational studies, bringing a variety of benefits to medical neuroengineering.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123798192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1