2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)最新文献

Activating a 2×2 Network of hNT Astrocytes with UV Laser Stimulation 紫外线激光刺激激活hNT星形胶质细胞2×2网络

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-20 DOI: 10.1109/NER.2019.8717185

Si Li, M. Simpson, E. S. Graham, C. Unsworth

引用次数: 3

Single Cell Grid Networks of Human Astrocytes On Chip 人类星形胶质细胞芯片的单细胞网格网络

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-20 DOI: 10.1109/NER.2019.8717032

Si Li, M. Simpson, E. S. Graham, C. Unsworth

引用次数: 4

Investigation of Insertion Method to Achieve Chronic Recording Stability of a Semi-Rigid Implantable Neural Probe 实现半刚性植入式神经探针长期记录稳定性的插入方法研究

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-20 DOI: 10.1109/NER.2019.8717128

M. Cavuto, T. Constandinou

{"title":"Investigation of Insertion Method to Achieve Chronic Recording Stability of a Semi-Rigid Implantable Neural Probe","authors":"M. Cavuto, T. Constandinou","doi":"10.1109/NER.2019.8717128","DOIUrl":"https://doi.org/10.1109/NER.2019.8717128","url":null,"abstract":"Brain machine interfaces notoriously face difficulties in achieving long term implanted recording stability. It has been shown that damage and inflammation, caused during insertion by electrodes that are too large and stiff, provoke a sustained inflammatory tissue response. This is commonly referred to as the foreign body response, resulting in encapsulation and thus increased electrode impedance over time. Accordingly, neural interfaces with ever smaller and more flexible electrodes are continually in development, but unfortunately face challenges of their own, first and foremost of which is buckling and bending during insertion. This work presents the development of a prototype insertion method, comprising an insertion device and novel probe architecture, that promotes straight insertion without buckling, while simultaneously minimizing the insertion force for multi-microwire electrode probes. When compared against insertion of probes with unsupported free electrodes, the prototype method achieved significantly straighter electrode insertion, resulting in both a smaller distance between electrode recording tips and a greater average insertion depth. While achieving less straight insertion than probes with sucrose coated electrodes, a common technique for promoting reliable insertion without buckling, the tested method was able to maintain significantly lower insertion forces.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121592817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Assistive Robot Arm Controlled by a P300-based Brain Machine Interface for Daily Activities 基于p300的脑机接口控制的辅助机械臂日常活动

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-20 DOI: 10.1109/NER.2019.8717042

David R. Achanccaray, Juan M. Chau, Jairo Pirca, F. Sepulveda, M. Hayashibe

引用次数: 9

Visual Temporal Perception in Parkinson’s Disease Analyzed Using a Computer-Generated Graphical Tool 使用计算机生成的图形工具分析帕金森病的视觉时间感知

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8717099

Matthew Bernardinis, S. F. Atashzar, M. Jog, Rajnikant V. Patel

{"title":"Visual Temporal Perception in Parkinson’s Disease Analyzed Using a Computer-Generated Graphical Tool","authors":"Matthew Bernardinis, S. F. Atashzar, M. Jog, Rajnikant V. Patel","doi":"10.1109/NER.2019.8717099","DOIUrl":"https://doi.org/10.1109/NER.2019.8717099","url":null,"abstract":"Non-motor symptoms of Parkinson’s Disease (PD) are present in all stages of the disease, significantly affecting patient quality of life. Some previous work on temporal perception has seen abnormalities occurring in PD, highlighting the Basal Ganglia’s (BG) role on this perception. However, these studies have not considered patient perceptual ability based on the tested time scale, even though the BG’s postulated influence on temporal processing is limited to certain time scales. Furthermore, it is not clear what effect Levodopa medication has on temporal perception for PD patients. This study examines the perception of vision-based temporal perception in different time scales for PD patients, and the effect of Levodopa medication via a two-forced alternative choice task using a computer-generated graphical tool. For this, perceptual ability (quantified using the subject’s difference threshold obtained through cumulative Gaussian functions) of 21 patients with PD was evaluated OFF and ON Levodopa medication, compared to 17 age-matched healthy participants. Individuals with PD displayed no impairments in perceiving time in the range of milliseconds, however in the range of seconds temporal perception was significantly impaired. This provides evidence for current timing models involving cerebellar control for millisecond timing, and BG influenced timing in the range of seconds to minutes. Furthermore, Levodopa showed no significant effects on visual temporal discrimination.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116734585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiclass Detection and Tracking of Transient Motor Activation based on Decomposed Myoelectric Signals 基于分解肌电信号的瞬态运动激活多类检测与跟踪

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8717077

Martyna Stachaczyk, S. F. Atashzar, S. Dupan, I. Vujaklija, D. Farina

{"title":"Multiclass Detection and Tracking of Transient Motor Activation based on Decomposed Myoelectric Signals","authors":"Martyna Stachaczyk, S. F. Atashzar, S. Dupan, I. Vujaklija, D. Farina","doi":"10.1109/NER.2019.8717077","DOIUrl":"https://doi.org/10.1109/NER.2019.8717077","url":null,"abstract":"Performance and efficacy of neuroprosthetic devices depend critically on the ability to detect the users motor intent with high temporal resolution. Delayed and incorrect responses significantly reduce usability, controllability and intuitiveness of prosthetic systems. Substantial efforts have been conducted to detect the steady-state phase of motor intention. However, detection, classification, and tracking of transient phases for one complete muscle contraction is still not possible. Clinically-established control systems rely mainly on surface electromyography (sEMG) signals in stationary, steady-state contractions, that have limited temporal resolution. Characterization of neural activities during different stages of a dynamic, transient contraction would allow for the development of a clinically-viable myoelectric system with a high temporal resolution that can significantly enhance the level of intuitiveness and usability of prosthetic devices. This could increase the response bandwidth and realize natural and dexterous control while avoiding exaggerated compensatory movements. For this purpose, in this paper, we explore the use of motor unit action potential trains (MUAPTs) for designing a movement intention detection technique. The goal is to classify and track the transient phases of muscle activation. Data collected from three subjects, during flexion tasks with four individual digits, is used to evaluate the algorithm. The performance is compared with that of the standard sEMG-based approach. Results showed a substantial advantage of the MUAPT-based phase detection algorithm over the conventional sEMG-based technique. It is confirmed that decoding, classification, and tracking of all stages of a dynamic, transient contraction is feasible using the proposed MUAPT-based approach, as a robust and efficient alternative for conventional sEMG-based algorithms.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128889444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Role of Cross-Frequency Coupling in the Frontal and Parieto-Occipital Subnetwork during Creative Ideation 创造性思维中交叉频率耦合在额叶和顶叶枕叶子网络中的作用

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8717163

R. Bose, Andrei Dragomir, F. Taya, N. Thakor, Anastasios Bezerianos

{"title":"Role of Cross-Frequency Coupling in the Frontal and Parieto-Occipital Subnetwork during Creative Ideation","authors":"R. Bose, Andrei Dragomir, F. Taya, N. Thakor, Anastasios Bezerianos","doi":"10.1109/NER.2019.8717163","DOIUrl":"https://doi.org/10.1109/NER.2019.8717163","url":null,"abstract":"In this study, we investigate the role of cross-frequency coupling (CFC) between the low frequency frontal (F) oscillations and high frequency parieto-occipital (PO) oscillations in creative ideation. These long distance brain interactions have been associated with cognitive processes like working memory (WM). We analyzed the α-γ, θ-α and θ-γ coupling for three different phases (early, mid and late) of creative ideation. We used Alternate Uses (AU) task as experimental paradigm for generating creative thinking and Object Characteristics (OC) task as the control. The results indicate significantly higher F to PO connection for AU compared to OC across all the three tested CFCs, in the early phase of creative ideation. Further, our results suggest that the late phase of creative ideation is associated with significantly lower θ-α and θ-γ coupling but higher α-γ coupling compared to OC. The results demonstrate that these F to PO cross-frequency interactions, associated with the WM subnetworks, play a major role in creative ideation. Further, our results suggest α-γ interaction in the early phase of creative ideation to be a potential biomarker for individual differences in creativity.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117010844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Information Transmission through Temporal Structure in Synchronous spikes 同步尖峰中时间结构中的信息传输

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8717154

Chaofei Hong, Jiang Wang, Y. Che

引用次数: 0

Modulation of neuronal input-output function by subthreshold electric fields from dendritic sublinear integration 树突亚线性积分的阈下电场对神经元输入输出函数的调制

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8716930

Yaqin Fan, Xile Wei, Meili Lu, Jiang Wang, Guo-sheng Yi, Y. Che

{"title":"Modulation of neuronal input-output function by subthreshold electric fields from dendritic sublinear integration","authors":"Yaqin Fan, Xile Wei, Meili Lu, Jiang Wang, Guo-sheng Yi, Y. Che","doi":"10.1109/NER.2019.8716930","DOIUrl":"https://doi.org/10.1109/NER.2019.8716930","url":null,"abstract":"Electrical field (EF) is a popular tool for both basic research and clinical applications, its actions on neuronal activities have been investigated from physiological mechanism and dynamics. However, few studies explore its modulatory influence on neuronal computation from the point of view of dendritic sublinear integration caused by passive dendrites which play an important role in neuronal computation. Here with a reduced biophysical model this problem is explained by observing the impact of EF on neuronal computation and dendritic sublinear operation. It is found that the positive EF results in more linear dendritic sublinear integration because of hyperpolarization in distal dendrites together resulting in higher neuronal excitability in neuronal computation but negative EF inhibits this ability due to more pronounced dendritic sublinear operation resulting from the hyperpolarization in distal dendrites. Further, we explain the modulation of positive EF on dysfunctional neuron combining with Feature Binding Problem. This work builds the gap between neuronal computation and dendritic sublinear operation, which is helpful to understand the modulation of EFs on brain functions.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116651738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Computationally Efficient Model for Predicting Successful Memory Encoding Using Machine-Learning-based EEG Channel Selection 基于机器学习的脑电通道选择预测成功记忆编码的高效计算模型

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER) Pub Date : 2019-05-16 DOI: 10.1109/NER.2019.8717057

Krishnakant V. Saboo, Y. Varatharajah, Brent M. Berry, M. Sperling, R. Gorniak, K. Davis, B. Jobst, R. Gross, B. Lega, S. Sheth, M. Kahana, M. Kucewicz, G. Worrell, R. Iyer

{"title":"A Computationally Efficient Model for Predicting Successful Memory Encoding Using Machine-Learning-based EEG Channel Selection","authors":"Krishnakant V. Saboo, Y. Varatharajah, Brent M. Berry, M. Sperling, R. Gorniak, K. Davis, B. Jobst, R. Gross, B. Lega, S. Sheth, M. Kahana, M. Kucewicz, G. Worrell, R. Iyer","doi":"10.1109/NER.2019.8717057","DOIUrl":"https://doi.org/10.1109/NER.2019.8717057","url":null,"abstract":"Computational cost is an important consideration for memory encoding prediction models that use data from dozens of implanted electrodes. We propose a method to reduce computational expense by selecting a subset of all the electrodes to build the prediction model. The electrodes were selected based on their likelihood of measuring brain activity useful for predicting memory encoding better than chance (in terms of AUC). A logistic regression prediction model was built using spectral features of intracranial electroencephalography (iEEG) from the selected electrodes. We demonstrate our method on iEEG data from 37 human subjects performing free recall verbal short-term memory tasks. The method achieves a 36.3% reduction in the number of electrodes used for prediction, resulting in a 64.9% reduction in inference computation time with just a 0.3% loss in prediction performance compared to the case when all electrodes were used. The electrodes selected using our method provided improved prediction performance compared to those electrodes that were not selected in 31 out of 37 patients. Building upon this observation, we also developed a method to identify the subjects for whom the proposed electrode selection method would be beneficial.","PeriodicalId":356177,"journal":{"name":"2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126178041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4