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引用次数: 4
摘要
在本文中，我们首次展示了如何在聚苯乙烯- c /SiO2基质上绘制人类hNT星形胶质细胞的网格网络，直到单细胞水平。我们证明了星形胶质细胞网络的功能通过钙释放引入ATP，并表明这是类似的控制样本。因此，我们证明了聚苯乙烯- c /SiO2平台是在单细胞水平上研究胶质网络的可行方法。
Single Cell Grid Networks of Human Astrocytes On Chip
In this paper, we demonstrate, for the first time, how we can pattern grid networks of human hNT astrocytes on parylene-C/SiO2 substrates down to the single cell level. We demonstrate that the functionality of the astrocyte networks by calcium release on the introduction of ATP and show that this is similar to that of a control sample. Thus, we demonstrate that the parylene-C/SiO2 platform is a viable way to investigate glial networks at the single cell level.
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