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Japanese Journal of Cancer and Chemotherapy最新文献

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[Invasive Ductal Carcinoma with Total Infarction and Necrosis-Case Report and Literature Review]. 浸润性导管癌伴全梗死及坏死1例报告及文献复习。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Makoto Nagahara, Koji Tezuka
{"title":"[Invasive Ductal Carcinoma with Total Infarction and Necrosis-Case Report and Literature Review].","authors":"Makoto Nagahara, Koji Tezuka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 71-year-old woman visited our hospital with pain and itching in her left breast which had commenced the day before admission. On palpation, we detected a 2.0 cm nodule, indicative of an elastic and hard tumor located centrally in the left breast. Mammography revealed an oval, microlobulated mass in the central quadrant of the left breast. Ultrasonography indicated a 1.5×1.3 cm hypoechoic lesion at the 12 o'clock position near the left nipple. Core needle biopsy revealed an invasive ductal carcinoma. Therefore, we mastectomized the left breast. Histologically, the tumor mass exhibited total necrosis, with viable carcinoma cells detected in a paramammary lymph node at the resected breast edge. Consequently, the tumor was diagnosed as a solid tubular carcinoma with total infarction and necrosis. Here, we present a rare case of breast cancer associated with infarction and necrosis.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1255-1258"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Long-Term Survival in Esophagogastric Junction Cancer with Multiple Lymph Node Metastasis Through Pre-and-Post Operative Chemotherapy]. [食管胃结癌伴多发淋巴结转移术后化疗的远期生存率]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Satoru Matono, Takafumi Ohchi, Sho Setojima, Takahiro Inutsuka, Atsushi Kaibara, Naoki Mori, Kohei Saisho, Masashi Nakagawa, Haruhiro Hino, Masahiro Fujisaki, Nobuya Ishibashi, Toshiaki Tanaka, Fumihiko Fujita
{"title":"[Long-Term Survival in Esophagogastric Junction Cancer with Multiple Lymph Node Metastasis Through Pre-and-Post Operative Chemotherapy].","authors":"Satoru Matono, Takafumi Ohchi, Sho Setojima, Takahiro Inutsuka, Atsushi Kaibara, Naoki Mori, Kohei Saisho, Masashi Nakagawa, Haruhiro Hino, Masahiro Fujisaki, Nobuya Ishibashi, Toshiaki Tanaka, Fumihiko Fujita","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 62-year-old man was diagnosed with Stage Ⅲ signet ring cell carcinoma of the lower thoracic esophagus. The patient underwent 2 courses of neoadjuvant cisplatin and 5-fluorouracil(SP therapy), demonstrating stable efficacy. Subsequently, the patient underwent subtotal esophagectomy with thoracoabdominal 2-field lymphadenectomy via right thoracotomy, followed by esophageal reconstruction using a gastric tube through a retrosternal route. Pathological examination revealed a signet ring cell carcinoma of the esophagogastric junction(pT3, pN2, sM0, and fStage Ⅲ). Postoperatively, the patient received chemotherapy with S-1 for 2 years owing to multiple lymph node metastases. Remarkably, the patient remained free of recurrence 6 years after surgery. We encountered a case of long-term survival in esophagogastric junction cancer with multiple lymph node metastases, typically associated with poor prognosis, following pre- and postoperative chemotherapy and radical surgery.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1259-1262"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Breast and Endocrine Tumor Best Practice of Adjuvant Therapy for Luminal Type Breast Cancer Based on either Clinico-Pathological Data Nor Genomic Analysis]. [乳腺和内分泌肿瘤基于临床病理数据和基因组分析的腔型乳腺癌辅助治疗的最佳实践]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Toshiaki Saeki
{"title":"[Breast and Endocrine Tumor Best Practice of Adjuvant Therapy for Luminal Type Breast Cancer Based on either Clinico-Pathological Data Nor Genomic Analysis].","authors":"Toshiaki Saeki","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1204"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Case of a Pleomorphic Carcinoma Successfully Treated with Nivolumab and Ipilimumab]. [尼武单抗与伊匹单抗联合成功治疗一例多形性癌]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Takashi Nishimura, Tsuyoshi Fujioka, Tadanobu Hatsu, Tadashi Okamoto, Naoto Takase, Nobuyuki Katakami, Shohei Matsuo
{"title":"[Case of a Pleomorphic Carcinoma Successfully Treated with Nivolumab and Ipilimumab].","authors":"Takashi Nishimura, Tsuyoshi Fujioka, Tadanobu Hatsu, Tadashi Okamoto, Naoto Takase, Nobuyuki Katakami, Shohei Matsuo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Case: </strong>A 70-year-old man was referred to our hospital for an abnormal chest X-ray shadow. A chest CT scan showed a mass shadow with a cavitary lesion in segment 6 of the right lung. One year after radical resection(resection of the lower lobe of the right lung; pT2aN0M0, pStage ⅠB), the patient exhibited enlarged mediastinal lymph nodes and liver metastases, and postoperative recurrence was determined. After treatment with the immune checkpoint inhibitors nivolumab(Nivo)and ipilimumab(Ipi), the mediastinal lymph nodes and liver metastatic lesions shrunk markedly, and a complete response was achieved. The complete response persisted for over 21 months after treatment cessation and 30 months after starting treatment. Therefore, Nivo/Ipi therapy is useful for metastatic pulmonary pleomorphic carcinoma with low programmed cell death ligand-1 expression.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1239-1241"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ⅳ. Predicting the Therapeutic Effect of Adjuvant Therapy with S-1 in Hormone Receptor-Positive, HER2-Negative Early Breast Cancer Based on Recurrence Risk-A Post-Hoc Exploratory Analysis of the POTENT Trial]. Ⅳ。基于复发风险预测S-1辅助治疗激素受体阳性、her2阴性早期乳腺癌的疗效[一项有效试验的事后探索性分析]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Masahiro Ohara
{"title":"[Ⅳ. Predicting the Therapeutic Effect of Adjuvant Therapy with S-1 in Hormone Receptor-Positive, HER2-Negative Early Breast Cancer Based on Recurrence Risk-A Post-Hoc Exploratory Analysis of the POTENT Trial].","authors":"Masahiro Ohara","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1216-1219"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[ACP and Ethics]. [ACP和道德]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Michio Miyasaka
{"title":"[ACP and Ethics].","authors":"Michio Miyasaka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since the 1970s, medical ethics has evolved from an informal approach to a more structured public discourse. The 4 principles proposed by Beauchamp and Childress in 1979 have gained international recognition and are useful for organizing ethical issues. However, this methodology has its limitations, and dialogue-based ethics are becoming increasingly important. Healthcare providers face 2 conflicting responsibilities: delaying death and ensuring a peaceful death, which are central to ethical considerations. Additionally, Japan's lack of legal clarity on life-shortening procedures introduces further ethical challenges. The ethical issues in advance care planning(ACP)include:(1)the shift from informal to public discourse ethics, (2)developing a methodology with dual focuses on ethical principles and dialogue, and(3)the acceptance of life-shortening procedures based on autonomy. While ACP as a public-opinion ethics approach will face challenges in creating forums for discussion, especially on the topic of death, improving proficiency in ethical principles and dialogue-based methodologies among medical professionals may address some of these issues. The extent to which life-shortening procedures should be tolerated remains a significant challenge and necessitates prompt legislative development.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1200-1203"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A Case of Primary Angiosarcoma of the Small Intestine Triggered by Gastrointestinal Bleeding]. 【消化道出血引发原发性小肠血管肉瘤1例】。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Kensuke Kakisako, Shumpei Mukai, Noriyuki Ogata, Chihiro Koike, Souta Komai, Shouhei Matsudo, Koki Shibata, Kei Tateno, Mihoko Nakagawa, Hiroaki Kobayashi, Yojiro Takano, Junichi Seki, Shoji Shimada, Kenta Nakahara, Yoshiaki Ozawa, Yusuke Takehara, Yuta Enami, Naruhiko Sawada, Fumio Ishida, Shinei Kudo
{"title":"[A Case of Primary Angiosarcoma of the Small Intestine Triggered by Gastrointestinal Bleeding].","authors":"Kensuke Kakisako, Shumpei Mukai, Noriyuki Ogata, Chihiro Koike, Souta Komai, Shouhei Matsudo, Koki Shibata, Kei Tateno, Mihoko Nakagawa, Hiroaki Kobayashi, Yojiro Takano, Junichi Seki, Shoji Shimada, Kenta Nakahara, Yoshiaki Ozawa, Yusuke Takehara, Yuta Enami, Naruhiko Sawada, Fumio Ishida, Shinei Kudo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An 87-year-old man with complaints of palpitations and digestive bleeding previously visited another hospital. He was referred to our hospital because of anemia. Small bowel endoscopy revealed an elevated lesion with bleeding from the ileum. Partial resection of the small intestine was performed, and small intestinal angiosarcoma was diagnosed. The patient was referred to another hospital upon his request. Radiotherapy was performed for tertiary chest metastases. Nine months after the surgery, the patient visited our hospital with hematochezia. Surgery was performed because of suspected recurrence at the anastomotic site. Histopathological examination confirmed the recurrence of angiosarcoma of the small intestine. The patient is currently undergoing outpatient observation. Angiosarcoma has a poor prognosis, although it is important to select the appropriate treatment according to the patient's age and general condition.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1267-1270"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ⅱ. Recurrence Score in Patients with BRCA1/2 Mutation from the OlympiA and TAILORx Trial Results]. Ⅱ。来自OlympiA和TAILORx的BRCA1/2突变患者的复发评分[a]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Yuko Takahashi, Takahiro Tsukioki, Tsuguo Iwatani, Tadahiko Shien
{"title":"[Ⅱ. Recurrence Score in Patients with BRCA1/2 Mutation from the OlympiA and TAILORx Trial Results].","authors":"Yuko Takahashi, Takahiro Tsukioki, Tsuguo Iwatani, Tadahiko Shien","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1209-1211"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A Case of Hepatocellular Carcinoma with Simultaneous Bone Metastasis Successfully Treated with Multidisciplinary Therapy]. [1例肝细胞癌合并骨转移经多学科治疗成功]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Toshihiko Goto, Susumu Sawada, Kunpei Ishida, Rina Ko, Yuta Iwasaki, Nozomu Nakanishi, Koshiro Morino, Norihiro Shimoike, Hirokazu Tanaka, Ryo Matsusue, Michihiro Yamamoto, Takafumi Machimoto
{"title":"[A Case of Hepatocellular Carcinoma with Simultaneous Bone Metastasis Successfully Treated with Multidisciplinary Therapy].","authors":"Toshihiko Goto, Susumu Sawada, Kunpei Ishida, Rina Ko, Yuta Iwasaki, Nozomu Nakanishi, Koshiro Morino, Norihiro Shimoike, Hirokazu Tanaka, Ryo Matsusue, Michihiro Yamamoto, Takafumi Machimoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The patient was a 52-year-old male, who, after experiencing lower back pain, underwent further investigation and was diagnosed with hepatocellular carcinoma with sacral metastasis. The hepatocellular carcinoma was a 9 cm tumor with a risk of rupture. Liver resection was performed, and lenvatinib was initiated at a dose of 4 mg/day postoperatively. Radical radiation therapy was then administered to address bone metastases. Lenvatinib was discontinued after 15 months due to skin disorders. Seven months have passed since the discontinuation of lenvatinib and 2 years since surgery. The patient's condition has progressed without any recurrence.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1243-1245"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A Case of Pathological Complete Response after Nivolumab Therapy in Unresectable Advanced Gastric Cancer]. [尼武单抗治疗不能切除的晚期胃癌病理完全缓解1例]。
Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-12-01
Rei Ogura, Kazuhiro Migita, Ayumi Nishioka, Yusuke Komeda, Tadashi Nakagawa, Takashi Inoue, Yasuyuki Nakata, Takahiro Yoshikawa, Naoki Kamitani, Daiki Nezu, Hiromi Kanai, Tomohiro Kubo, Manabu Matsushita, Hideki Matsuo, Kei Moriya, Saiho Ko
{"title":"[A Case of Pathological Complete Response after Nivolumab Therapy in Unresectable Advanced Gastric Cancer].","authors":"Rei Ogura, Kazuhiro Migita, Ayumi Nishioka, Yusuke Komeda, Tadashi Nakagawa, Takashi Inoue, Yasuyuki Nakata, Takahiro Yoshikawa, Naoki Kamitani, Daiki Nezu, Hiromi Kanai, Tomohiro Kubo, Manabu Matsushita, Hideki Matsuo, Kei Moriya, Saiho Ko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 70-year-old man was admitted to a local hospital with epigastric pain and diagnosed with type-2 gastric cancer. Contrast-enhanced CT scan showed metastases in S3 and S8 of the liver, and the tumor was classified as type cT4aN2H1, cStage ⅣB. Nivolumab monotherapy was initiated after failure of treatment with S-1 plus oxaliplatin and ramucirumab. After 6 courses, the primary tumor, lymph nodes, and liver metastases had shrunk to a remarkable degree. The patient underwent a proximal gastrectomy with D2 lymph node dissection and partial liver resection. Histopathological examination revealed no remaining tumor cells, with a histological response Grade 3.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 12","pages":"1263-1265"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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