[Large Primary Hepatic Neuroendocrine Tumor with Right Trisectionectomy-A Case Report].

Q4 Medicine
Ryohei Aoyama, Takumi Miyamoto, Kentaro Yasuchika, Masaya Tsubakiyama, Hyoma Terawaki, Yusuke Sakura, Hideaki Tsujii
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引用次数: 0

Abstract

A large mass in the liver was incidentally observed on abdominal ultrasonography of a 75‒year‒old female during health surveillance. Computed tomography (CT) and magnetic resonance imaging revealed a tumor (φ>12 cm) in the medial segment of the liver. A liver biopsy was performed, and the tumor was histopathologically diagnosed as a neuroendocrine tumor (NET) G1. 18F‒fluorodeoxyglucose positron emission tomography‒CT (PET‒CT) and somatostatin receptor scintigraphy (SRS) revealed concomitant uptake in the hepatic tumor and no abnormal uptake in other organs; thus, the tumor was diagnosed as a primary hepatic NET (PHNET). Radical resection required right trisectionectomy of the liver, with little future remnant liver volume. The radical resection was performed 3 weeks post portal embolization. There were no surgical complications or obvious recurrence for 1 year post‒surgery. PHNETs are extremely rare and are difficult to diagnose using routine imaging modalities. PET‒CT and SRS are useful to exclude the presence of extrahepatic lesions and histopathological examination is required to diagnose PHNETs. Surgical resection is the first‒line treatment for PHNETs and even if the PHNET is large, a favorable prognosis can be achieved with radical resection.

【原发性肝脏大神经内分泌肿瘤伴右侧三节切除术1例】。
一位75岁女性在健康监护期间,腹部超声检查发现肝脏内有一大块肿块。计算机断层扫描(CT)和磁共振成像显示肝脏内侧段肿瘤(φ>12 cm)。行肝活检,病理诊断为神经内分泌肿瘤(NET) G1。18f -氟脱氧葡萄糖正电子发射断层扫描(PET-CT)和生长抑素受体显像(SRS)显示肝脏肿瘤同时摄取,其他器官未见异常摄取;因此,该肿瘤被诊断为原发性肝NET (PHNET)。根治性切除需要右肝三节切除术,未来剩余肝体积很小。门静脉栓塞后3周行根治性切除。术后1年无手术并发症,无明显复发。PHNETs极为罕见,难以用常规成像方式诊断。PET-CT和SRS有助于排除肝外病变的存在,诊断PHNETs需要组织病理学检查。手术切除是PHNETs的一线治疗方法,即使PHNET很大,根治性切除也能获得良好的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
0.20
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