Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo最新文献_第8页

[Demographic and professional risks of depopulation among working population in Russia: 14 years later (analytical review).] [俄罗斯劳动人口减少的人口和职业风险：14 年之后（分析评论）]。

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

A S Bashkireva, A V Shishko, D Y Bogdanova, P P Anikeev

{"title":"[Demographic and professional risks of depopulation among working population in Russia: 14 years later (analytical review).]","authors":"A S Bashkireva, A V Shishko, D Y Bogdanova, P P Anikeev","doi":"","DOIUrl":"","url":null,"abstract":"The article presents a comparative analysis of the process of population aging in the context of demographic and professional risks of depopulation among working population in Russia. The values of the main medical and demographic indicators of population aging for Russia and developed countries were given. The results of UN forecasts, probabilistic forecasts of the total number and some characteristics of the age-sex structure for the population of the Russian Federation were analyzed. The state of demographic disadvantage in Russia and in the world was convincingly shown. Particular attention was paid to the consideration of the demographic risks of a reduction in the working-age population and an increase in the burden on the working-age population. The need for further research on the use of geroprotectors and modern gerontotechnologies as means and methods for preventing premature decline in work ability, slowing down the aging process of workers, reducing the mortality rate among working population and increasing professional longevity has been proven.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 3","pages":"198-207"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Peptidergic regulation of expression of cellular aging marker proteins in buccal epithelium.] 口腔上皮细胞衰老标志蛋白表达的肽能调控。

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

O M Ivko, S V Trofimova, A V Trofimov, Z Sharkovich, V A Mogilev

{"title":"[Peptidergic regulation of expression of cellular aging marker proteins in buccal epithelium.]","authors":"O M Ivko, S V Trofimova, A V Trofimov, Z Sharkovich, V A Mogilev","doi":"","DOIUrl":"","url":null,"abstract":"The review presents the results of long-term research conducted by the staff of the Saint-Petersburg Institute of Bioregulation and Gerontology, dedicated to the study of the biological activity of peptide bioregulators at all levels of a living organism's organization. This review compares the findings of domestic and international studies in this field. At the same time, the priority of Russian scientists in the use of buccal epithelium as a diagnostic marker of age-associated pathology is indicated. This topic is widely studied around the world, but the leading role belongs to domestic scientists. Over the last century, there has been a significant shift in the way aging is viewed. Unlike in earlier centuries, when aging was primarily seen through social and ethical lenses, modern science approaches it as a physiological process with specific mechanisms within the body. The study of the polypeptide complex in the epiphysis and AEDG peptide revealed an effect on human circadian rhythms, as well as an increase in melatonin secretion in elderly people and those with reduced melatonin-producing function. This effect is achieved at the cellular level by regulating the expression of genes involved in circadian rhythms (Cry2, AANAT, ASMT, CLOCK), reducing the synthesis of proteins promoting apoptosis (p16, p21, p53), and regulating the synthesis of markers of functional cell activity (TERF-1, prohibitin, SIRT1, SIRT6). The results of this research indicate the potential of peptides from the epiphysis as new biologically active compounds that can stimulate melatonin production and correct circadian rhythm disorders in elderly and senile individuals.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 5","pages":"516-524"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Research of medical social effectiveness of family care to elderly patients with chronic limb ischemia.] 老年慢性肢体缺血患者家庭护理的医学社会效果研究

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

R S Goloshchapov-Aksenov, A G Koledinsky, D I Kicha, S A Bagin, O V Rukodaynyy, P S Volkov, A G Uteva

{"title":"[Research of medical social effectiveness of family care to elderly patients with chronic limb ischemia.]","authors":"R S Goloshchapov-Aksenov, A G Koledinsky, D I Kicha, S A Bagin, O V Rukodaynyy, P S Volkov, A G Uteva","doi":"","DOIUrl":"","url":null,"abstract":"Forms of family assistance to elderly patients with chronic limb ischemia (CLI) are based on the communication motivation of the subjects of the system «patient-family-doctor» and activation of the medical function of the family. Objective - to research the medical social effectiveness of family care for elderly patients with CLI. Objects of the research (2017-2024): patients with stage 2A-3 CLI (n=615), average age 76±5,8 years; family members of patients participating in integrated (joint) consultations with the sick relative. Patients were divided into 2 groups: group A - 513 patients with stage 2B-3 CLI with indications for surgical treatment of CLI; group B - 102 patients with stage 2A-2B CLI without indications for surgical treatment of CLI. The research of the medical function of the family was carried out on the basis of the experience of the specialized department using a special questionnaire. The observation period was 24 months. The share of primary integrated consultations in group A was 42%, in group B - 17,6% (p=0,001). After 24 months follow up, increase of integrated consultations in group A was 16,7%, in group B - 161,4%. Medical social effectiveness of family care for elderly patients was achieved in the processes of accessibility of medical care, controlled dispensaryzation, compliance to physician's recommendations and survival. 2-year survival of patients was 98,05% (in group A - 97,9%, in group B - 100%). Medical social efficiency of pre-medical family care for elderly patients with CLI is based on the autonomous and controlled behavior of the system subjects «patient-family-doctor», professional competence of cardiovascular surgeons, information management of dispensarysation and activation of the medical function of the family.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 6","pages":"765-776"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ageism among medical trainees and interns in Turkey and related factors. 土耳其医疗培训生和实习生中的年龄歧视及其相关因素。

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

M Picakciefe, E Tiric, B Dede, S Yesilbas, R Guven Cengiz, D Mulayim Gullu

{"title":"Ageism among medical trainees and interns in Turkey and related factors.","authors":"M Picakciefe, E Tiric, B Dede, S Yesilbas, R Guven Cengiz, D Mulayim Gullu","doi":"","DOIUrl":"","url":null,"abstract":"The aim of this study was to determine the attitudes of medical trainees and interns towards ageism and the factors that influence their attitudes. The population of the descriptive and cross-sectional study consisted of 165 trainees and 495 interns, a total of 660 medical students. The Turkish version of the Fraboni Scale of Ageism was used to evaluate attitudes toward older adult among medical students. Students of male gender, medical trainees, not living with grandparents, not visiting nursing homes, those who do not intend to pursue a career in geriatric medicine, and no prior care experiences with older adults were more likely to have negative attitudes toward older adults (p<0,05). The conclusion of this study was that the students who took part were more likely to have slightly negative attitudes toward older adults. However, medical trainees have more positive attitudes than interns. It is recommended that medical students should have a geriatric rotation, that students should be counseled on this issue, that ageing and the ageing process should be included more in the curriculum, and that interaction with older people in clinical practice and field studies should be increased.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 5","pages":"491-498"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Association between anthropometric indices with the risk of hypoglycemia in elderly patients with type 2 diabetes mellitus]. [人体测量指数与老年 2 型糖尿病患者低血糖风险之间的关系]。

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

P Y Merzlova, S V Bulgakova, D P Kurmaev, E V Treneva, L A Sharonova, O V Kosareva, Y A Dolgikh

引用次数: 0

[The effect of various visual impairments on the daily activities of older patients.] [各种视力障碍对老年患者日常活动的影响]

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

E A Yaroshevich, A D Gnezdilova

{"title":"[The effect of various visual impairments on the daily activities of older patients.]","authors":"E A Yaroshevich, A D Gnezdilova","doi":"","DOIUrl":"","url":null,"abstract":"Visual impairment due to ophthalmological diseases significantly affects functional activity in everyday life, since good eyesight is crucial in daily activities. Data from 837 respondents were studied, allowing for analysis of such medical and demographic indicators as age, gender, level of education, visual acuity arterial hypertension and diabetes mellitus. To measure functional status, the main activities in daily life (ADL) and instrumental activities in daily life (IADL) were evaluated using a modified version of the Katz scale and the IADL OARS scale. Statistical methods of Mantel-Hansel Chi-squared analysis were used to assess differences in the prevalence of functional blindness and visual deficit. The study showed that medical and demographic factors have a relatively smaller impact on vision deficiency compared to functional blindness, with age being a significant factor in both cases. Among the medical and demographic factors, the age of patients, as well as diabetes mellitus, significantly increase the development of visual deficiency and functional blindness. Functional blindness, in comparison with visual deficiency, causes more significant restrictions on activities in everyday life and instrumental activities in everyday life, and also causes dependence on help from others.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 3","pages":"238-242"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Functional recovery in older inpatients with hypertension and ischemic heart disease post-COVID-19.] [COVID-19后高血压和缺血性心脏病老年住院患者的功能恢复]。

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

K F Borchev, E O Shirshova, A S Solodovnik, D V Bondarev

{"title":"[Functional recovery in older inpatients with hypertension and ischemic heart disease post-COVID-19.]","authors":"K F Borchev, E O Shirshova, A S Solodovnik, D V Bondarev","doi":"","DOIUrl":"","url":null,"abstract":"Understanding the recovery process of functional abilities post-COVID-19 in older inpatients with arterial hypertension and ischemic heart disease is important for optimising healthcare delivery and resources. Participants in this study were individuals undergoing hospital-based rehabilitation following COVID-19 (average age 66, n=183). They were categorised into groups with arterial hypertension (n=92), ischemic heart disease (n=18), both conditions (n=38), and a control group without these diseases (n=35). Functional abilities were assessed via the distance walked until signs of exhaustion (meters), handgrip strength (kilograms), and breath-holding time (seconds). Multiple regression analysis revealed that inpatients with arterial hypertension walked shorter distances (β=-19,183; p=0,050) but showed higher handgrip strength (β=3,735; p=0,025) compared to the control group. Post-rehabilitation, inpatients with hypertension demonstrated greater performance (β=40,435, p=0,024) and better improvement rates (β=47,337; p=0,016) in walked distance than those in the control group. Significant interaction effects between groups and pre-/post-rehabilitation changes were observed only for walking distance (β=34,74; p=0,02), with no significant interactions found for other measures. The findings indicate that older inpatients with arterial hypertension may experience comparable or enhanced recovery of functional abilities post-COVID-19. The presence of ischemic heart disease, alone or combined with hypertension, does not significantly impair rehabilitation outcomes compared to those without such conditions.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 1-2","pages":"122-129"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Chronic kidney disease and accelerated aging: the role of comprehensive geriatric assessment.] [慢性肾脏病与加速衰老：老年病综合评估的作用]

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

A L Ariev, E S Lapteva

{"title":"[Chronic kidney disease and accelerated aging: the role of comprehensive geriatric assessment.]","authors":"A L Ariev, E S Lapteva","doi":"","DOIUrl":"","url":null,"abstract":"This review presents data from the literature on the characteristics of the course of chronic kidney disease from the perspective of the geriatric patient. Chronic kidney disease and progression of renal failure is a prototype model of premature and accelerated aging. Many authors have stated that a better mechanistic understanding of the phenomenon of premature aging, early diagnosis of chronic kidney disease, and a geriatric approach to the patient can improve the effectiveness of management and prolongation of life in this category of patients. Comprehensive geriatric assessment is one of the most important tools used by geriatricians and their teams to globally assess elderly patients and plan effective interventions. It is concluded that the use of comprehensive geriatric assessment in patients with chronic kidney disease may improve the clinical status of patients and allow selection of patients who may benefit most from renal replacement therapy compared to a conservative approach. And even in the early stages of chronic kidney disease, a comprehensive geriatric assessment may be useful in formulating a complete intervention plan and optimizing quality of life, autonomy, and prognosis. However, despite recognition of the importance of comprehensive geriatric assessment, the means to implement this tool in nephrology departments have not been developed and require special training programs and appropriate skills. It is concluded that much more needs to be done to realize the continuity of nephrologists and geriatricians in the provision of meaningful skilled care to older patients with chronic kidney disease.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 1-2","pages":"111-121"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Possibilities of effective interaction in the system pharmacovigilance at registration of medicinal undesirable reactions at patients of the senior age groups.] [在登记老年患者的药物不良反应时，在药物警戒系统中进行有效互动的可能性]。

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

E O Kochkina, N V Verlan, G N Kovalskaya, E V Katamanova, L O Bessonova, A A Konovalova

{"title":"[Possibilities of effective interaction in the system pharmacovigilance at registration of medicinal undesirable reactions at patients of the senior age groups.]","authors":"E O Kochkina, N V Verlan, G N Kovalskaya, E V Katamanova, L O Bessonova, A A Konovalova","doi":"","DOIUrl":"","url":null,"abstract":"In recent years, complications of drug therapy are an important medical problem. Data on adverse drug reactions (ADR) in patients of older age groups were analyzed. The object of the study was notification cards for unwanted reactions received from medical organizations of the Irkutsk region for period 2009-2020 years. The Narangio scale was used to assess the causality between ADR and medicines. Of the 1021 ADR notifications in patients over 65 years of age, 2/3 (668) are presented with ADR notifications in women, 353 (34,6%) in men. The presence of background diseases was registered in 915 notifications (89,6%). There were no gender differences except for a higher incidence of chronic obstructive pulmonary disease in men (7,2 and 3,5% respectively, p<0,05) and diabetes mellitus in women (14 and 3,5% respectively, p<0,05). ADRs for antibacterial agents amounted to 31,8%, drugs for the treatment of cardiovascular diseases - 10,5%, cases of therapeutic inefficiency - 5,1%. The ADR data statement was in line with the recommended form of 76%. The most common filling defect was incomplete patient information. The validity of the Narango causation was high. The deadlines for reporting data were observed in 89,1%. For effective interaction in the pharmacovigilance system, it is necessary in each medical organization to constantly inform about the procedure for pharmacovigilance, types of ADRs, the rules for their detection and the timing of data reporting. The work should be supervised by a trained specialist.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 1-2","pages":"33-39"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Epidemiological analysis of comorbid diseases determining the prognosis of an elderly patient with type 2 diabetes mellitus.] [决定老年 2 型糖尿病患者预后的合并疾病流行病学分析]。

Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo Pub Date : 2024-01-01

N A Pervyshin, S V Bulgakova, A A Ladygina

{"title":"[Epidemiological analysis of comorbid diseases determining the prognosis of an elderly patient with type 2 diabetes mellitus.]","authors":"N A Pervyshin, S V Bulgakova, A A Ladygina","doi":"","DOIUrl":"","url":null,"abstract":"The article presents a detailed comparative analysis of the medical and demographic indicators of diseases and conditions that determine the prognosis of an elderly patient with type 2 diabetes mellitus (DM2) according to domestic and foreign sources. A systematic review of the results of epidemiological studies on the databases PubMed, Google Scholar, Elibrary, WHO, IDF sites, materials from Rosstat, the Ministry of Health of the Russian Federation and NMRC of Endocrinology for the following keywords: type 2 diabetes mellitus, chronic kidney diseases, heart failure, comorbidity, accompanying pathology, morbidity, prevention, mortality structure, complete epidemiological study, multicenter randomized trial. 51 relevant articles were selected from the 107 sources found according to the criteria of compliance. A quantitative assessment of the differences in the prevalence of comorbid diseases and individual syndromes between samples of elderly people, patients with DM2 and the general population in the Russian Federation and foreign countries was performed, as well as an analysis of the structure of mortality by causes in a cohort of patients with DM2, general trends were identified, and their detailed assessment from the standpoint of pathogenesis was given. It was revealed that the prevalence of CHF, CKD and significant comorbid diseases in the samples of elderly people and patients with DM2 significantly exceeds that in the population in the Russian Federation and foreign countries; in the DM2 cohort, mortality from cardiovascular causes and CKD in the Russian Federation is lower than abroad; concomitant hypertension in an elderly DM2 patient significantly increases the risk of an adverse cardiovascular outcome.","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"37 4","pages":"363-372"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0