{"title":"[Predictors of self-perception of the quality of life of people aged 60 years and older living in the Grodno region.]","authors":"M Y Surmach, P L Korneiko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Approaches to the classification and identification of boundaries of the elderly have been studied, the age structure of the population of the Republic of Belarus and the Grodno region has been calculated, using materials from a database representative of the Grodno region, and an analysis of the quality of life of persons aged 60+ has been carried out. It has been established that, in general, the state of medical and social predictors of self-perception of people 60 years of age and older in the Grodno region can be considered favorable, which is reflected in the maximum values of quality of life in the domains «Microsocial support» and «Social well-being» (95% CI 66,2±0,6%), and also that the integral level of quality of life corresponds to an increased level (64,26±0,52%). A demographically older population with expanded working capacity limits reduces the risk of stigmatization of the elderly. The domain «Physical and psychological well-being» revealed the lowest values (95% CI 61,52±0,55%). The domain has a direct connection with satisfaction with one's own health, with how a person in old age is able to compensate for accumulated disorders and what conditions he has for this. The measures taken in the Republic of Belarus in this direction in the healthcare system receive strong government support.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"156-162"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T V Tayutina, A V Lysenko, T M Kazaryan, E V Modebadze, M A Kaplunovskaya
{"title":"[The effect of arterial hypertension on the stimulation of angiogenesis and the severity of systemic inflammation in elderly patients with chronic obstructive lung disease.]","authors":"T V Tayutina, A V Lysenko, T M Kazaryan, E V Modebadze, M A Kaplunovskaya","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic obstructive pulmonary diseases occupy a significant place in the structure of diseases in the elderly and senile and contribute to the diversity and multiplicity of combined pathology, impaired quality of life and causes of mortality in the elderly. One of the leading tasks in the treatment of vascular disorders, which are of particular importance in arterial hypertension combined with COPD in elderly patients, is to improve macrohemodynamics and microcirculation by improving endothelial function, normalizing the relationship between the endothelium and blood cells, reducing the level of markers of chronic inflammation and angiogenesis. The aim of the work: to study the effect of arterial hypertension on the state of angiogenesis inducers in elderly patients with COPD. It has been established that in the development of isolated COPD, the activity of both platelet-derived growth factor AA and tumor necrosis factor α directly depends on age, smoking index and spirometric parameters, in particular, on the forced expiratory volume in first second. The development of concomitant arterial hypertension in elderly patients with COPD promotes stimulation of angiogenesis and an increase in the severity of systemic inflammation.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Joghataei, M Basakha, S Goharinezhad, M Ranjbar, H Rafiey, A Delbari, S H Mohaqeqi Kamal
{"title":"Well-being in old age: perspectives from older adults in Iran (a qualitative content analysis study).","authors":"F Joghataei, M Basakha, S Goharinezhad, M Ranjbar, H Rafiey, A Delbari, S H Mohaqeqi Kamal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The growing older adults' population made their well-being as a global concern. Considering the cultural and contextual differences across societies, it is essential to explore the dimensions of well-being within each specific context. This study aims to identify the dimensions of well-being from the perspective of Iranian older adults. This study employed a qualitative approach, conducting 21 in-depth interviews with older adults, selected through purposive sampling across different districts of Tehran. The interviews were analyzed based on directed content analysis. The findings were compared to a framework developed from a prior scoping review. Six dimensions of well-being identifies in the theoretical framework were confirmed through the interviews, though some subcategories differed. Key findings included: independence and autonomy in daily life and the burden of high healthcare expenditures under the Health dimension; warm family relationship and child's well-being in Social Relationships; inadequate income and financial hardship in Economic Status; recreational activities and trips in Environment and Leisure; and the role of education and literacy in Capabilities and Resources. Economic challenges were particularly impactful on the subjective well-being of older adults. Economic difficulties, peaceful family environment and children's well-being emerged as significant factors in the well-being of Iranian older adults compared to previous theoretical framework.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 2","pages":"197-206"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N M Agarkov, A S O Ibiev, T I Yakunchenko, A A Shorokhova
{"title":"[Association of age-related viability with systemic inflammation in low-energy fractures.]","authors":"N M Agarkov, A S O Ibiev, T I Yakunchenko, A A Shorokhova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study of biomarkers of age-related viability (resilience) in gerontology and geriatrics is actively continuing, but it has practically not been considered in patients with low-energy fractures. The aim of the study was to analyze the association of age-related viability with systemic inflammation in low-energy fractures. Among 102 patients after 2,5-3 months of low-energy fractures, stability in the motor and cognitive domains of walking speed, the 6-minute walking test and MMSE, respectively, were studied. A decrease in the motor domain was found in 78,43±3,61% of cases and the cognitive domain in 67,65±3,12% of cases (p<0,01). In patients with a decrease in the motor domain, the content of all pro-inflammatory cytokines is significantly higher compared to representatives with a decrease in the cognitive domain. This is especially true for the level of IL-6, which in patients with decreased motor domain was 30,4±1,5 pg/ml versus 12,1±0,8 pg/ml, TNF-α was 41,2±2,3 and 17,6±0,9 pg/ml, and IL-1b was 24,8±1,6 and 10,6±0,7 pg/ml, respectively. Multiple beta regression coefficients show a negative association with pro-inflammatory cytokines among both patients with low-energy fractures with a decrease in the motor domain and a decrease in the cognitive domain. However, the association with IL-10 is positive and the β coefficient was +1,95 for a decrease in the motor domain and +1,32 for a decrease in the cognitive domain.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 2","pages":"251-255"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O V Filatova, D D Mamyshev, E I Romashko, I Y Voronina, N A Shishkina, E V Kutseva, R I Khalimov, D N Sherbakov
{"title":"[Influence of phytocomposition with nootropic properties on the quality of life and psychoemotional state of middle-age and early elderly people.]","authors":"O V Filatova, D D Mamyshev, E I Romashko, I Y Voronina, N A Shishkina, E V Kutseva, R I Khalimov, D N Sherbakov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The use of nootropic drugs is one of the approaches to improving the mental health of older people and preventing at least some cognitive disorders. The study participants were volunteers - conditionally healthy individuals. Volunteers (n=35, average age 53,4±1,21 years) took the phytocomposition «Memoris» 1 capsule 2 times a day for two weeks. Participants in the comparison group (n=35, average age 53,8±1,12 years) received a placebo (maltodextrin). The severity of anxiety/depression was assessed using the HADS questionnaire. A specialized questionnaire to determine well-being, activity, mood was used to assess the psychosomatic state. The quality of life was studied using the standardized SF-36 questionnaire. Under the influence of the phytocomposition «Memoris» statistically significantly decreased the results on anxiety scale (from 7,4±0,64 to 5,7±0,56 points, p<0,001) and depression scale (from 5,9±0,52 to 4,4±0,46 points, p<0,001), increased the results on well-being scale (from 4,9±0,19 to 5,5±0,16 points, p<0,001), as well as mood scale (from 5,5±0,16 to 5,8±0,16 points, p=0,009). After taking the phytocomposition «Memoris» an increase in scores was registered in all categories of the SF-36 questionnaire. Thus, the obtained results indicate a positive effect of the phytocomposition «Memoris» on the indicators of anxiety and depression, well-being, mood and a significant increase in the quality of life of respondents.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D N Bobunov, E O Bilyk, Y O Dudar, T P Zavyalova, E V Vaganova, A V Dolba, D M Gebekova, A R Protsenko
{"title":"[Method of treating obesity in elderly and senile patients (1st stage).]","authors":"D N Bobunov, E O Bilyk, Y O Dudar, T P Zavyalova, E V Vaganova, A V Dolba, D M Gebekova, A R Protsenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the work is to evaluate the efficiency of the method of treating obesity in elderly and senile patients. The patients were offered 2 nutrition programs, one based on the obtained data (insulin resistance, biliary dyskinesia, type 2 diabetes, etc.) and the final diagnosis in connection with the concomitant disease, and the second based on their taste preferences. The peculiarity of the development of the dietary program was to prepare a menu based on lean body mass, and not the total mass obtained from the results of bioimpedancemetry. The ratio of proteins, fats and carbohydrates (in grams per kg of lean body mass is 1:1:2(3). Based on stress echo and lactate testing, a program of dosed aerobic physical activity was developed for the patient. Training was carried out 3-4 times a week after the last meal, the training time was 90 minutes with the required heart rate (not higher than aerobic threshold). Against the background of using the proposed technique, a reliable decrease in total body mass, body fat mass, total water was observed according to the results of bioimpedancemetry. Also, a reliable decrease in blood parameters: ALT, AST, gamma-GT, glucose, insulin, leptin, an increase in the level of vitamin D. Thus, the selection of a personalized diet in combination with dosed aerobic physical activity and regular monitoring using heart rate monitors will not only reduce weight, but also improve health indicators (reduce weight due to adipose tissue, reduce insulin resistance, increase vitamin D levels, reduce blood pressure, liver transaminases, glucose), and also increase the effectiveness of therapeutic measures for obesity, preventing the progression of complications.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"28-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G I Semenova, I V Erkomaishvili, A V Lysenko, D S Lysenko, L M Dmitrenko
{"title":"[Preservation of elderly people cognitive abilities by means of physical culture.]","authors":"G I Semenova, I V Erkomaishvili, A V Lysenko, D S Lysenko, L M Dmitrenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of distance learning using a modified Pilates system on cognitive abilities and quality of life of the third age people was studied. The set of exercises proposed by the authors contributed to a reliable increase in the indicators of physical, social, intellectual and emotional health, and the psychological status of the experimental group of non-working pensioners. The distance format of combined optimization of the motor regime and correction of cognitive abilities can be recommended to ensure systematic training at any time of the year and in any weather, which is critically important for the age group studied.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"112-117"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E M Ivanova, K O Kosmina, A U Shumkov, A M Zabezhinsky, A M Mayorova, K P Raevskii
{"title":"[The role of changes in the intestinal microbiota in the development of metabolic syndrome in the elderly (literature review).]","authors":"E M Ivanova, K O Kosmina, A U Shumkov, A M Zabezhinsky, A M Mayorova, K P Raevskii","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the modern world, considerable attention is paid to cardiovascular diseases, which, according to WHO, remain the leading cause of death. One of the key risk factors for their development is metabolic syndrome (MS), the prevalence of which is steadily increasing. An increase in the number of people with obesity, changes in eating behavior and reduced physical activity contribute to the progression of MS, and also affect the composition and functional state of the intestinal microbiota. In recent years, more and more data indicate that the microbiota plays an important role not only in the pathogenesis of MS, but also in the aging process. Gerontology considers intestinal microflora as one of the targets for action in order to slow down age-related changes and reduce the risk of age-associated diseases, including cardiovascular pathologies. Intestinal dysbiosis can contribute to the development of systemic inflammation, insulin resistance and atherosclerosis, which makes the study of its mechanisms in the context of gerontology particularly relevant. The search for new links in the pathogenesis of MS and its relationship with changes in the microbiota opens up prospects for the development of effective prevention and treatment strategies, which, in turn, can contribute to an increase in the duration and quality of life. The purpose of the review is to analyze and systematize modern scientific data on the relationship between intestinal microbiota, metabolic syndrome and aging processes, to identify new pathogenetic mechanisms and potential therapeutic targets for the prevention and treatment of age-associated diseases. The work uses publications, mainly for the last 5 years, from the PubMed, eLIBRARY, ScienceDirect databases, including review articles, meta-analyses and clinical studies.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 2","pages":"243-250"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y E Filippova, A N Ilnitskiy, T N Malishevskaya, V V Bashuk, E V Renzyak
{"title":"[Vascular aging, vascularity in the progression of primary open-angle glaucoma.]","authors":"Y E Filippova, A N Ilnitskiy, T N Malishevskaya, V V Bashuk, E V Renzyak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the aging of the population, the prevalence of age-associated diseases, including glaucoma, increases. Despite the contribution of vascular disorders to the development and progression of primary open-angle glaucoma (POAG), knowledge about the relationship between the ocular vascular bed and systemic vessels and sensory aging in glaucoma is limited. Objective: to determine how vascular aging and vascularity changes contribute to POAG progression. A total of 177 elderly patients (350 eyes) were examined. All patients underwent standard ophthalmological examination, assessment of sensory aging (Md, PSD indices, GCS indices according to OCT data, age and frailty), assessment of vascular parameters (reactive hyperemia test (RHT), ocular pulse and blood flow in the vessels of the extremities, lipidogram). Data analysis showed statistically significant changes in vascularity and vascular aging in elderly patients with POAG progression. Vascular and sensory aging are risk factors for POAG progression. The most significant predictors of glaucoma progression were identified - hemodynamic disorders, vascularity indices against the background of vascular aging in elderly patients.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 2","pages":"222-228"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N A Pervyshin, S V Bulgakova, R A Galkin, P A Lebedev, Y A Dolgikh
{"title":"[The structure of hypoglycemic therapy in a comorbid elderly patient with type 2 diabetes mellitus according to the outpatient specialized registry.]","authors":"N A Pervyshin, S V Bulgakova, R A Galkin, P A Lebedev, Y A Dolgikh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objective - a comprehensive clinical assessment of the structure of hypoglycemic therapy in an elderly patient with type 2 diabetes mellitus (DM2) with an emphasis on concomitant manifestations of metabolic syndrome (obesity, hypertension, dyslipidemia). The study was carried out according to a retrospective design; the sample consisted of 462 comorbid elderly patients with DM2, whose primary clinical data were stored and systematized in an outpatient registry using developed digital tools and a specialized formalized protocol. Indicators of clinical and metabolic status and the structure of hypoglycemic therapy were studied. A high prevalence of concomitant diseases (hypertension - 92%, obesity - 63%, dyslipidemia - 86%) was revealed, the pathogenesis of which is closely interrelated with insulin resistance and is associated with age. A significant discrepancy between the average values of key indicators of therapeutic control of diabetes and the target ranges was noted: HbA1c (8,35±2,02%), systolic blood pressure (134,93±9,48 mmHg), LDL (2,60±1,19 mmol/L). A high proportion of prescribing insulins (46,3%), including short-acting ones (22,6%), as well as drugs that stimulate glucose-independent insulin secretion (39,8%), was determined in the structure of sugar-lowering therapy, which indicates that the clinical manifestations of metabolic syndrome are not always taken into account when choosing therapeutic tactics.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"96-104"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}