Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo最新文献

{"title":"[Prospects for the development of geriatric rehabilitation: A review of current trends and innovations.]","authors":"D N Bobunov, M D Didur, V I Kartashova, A A Chudina, R A Skorikov, S A Belskaya, A D Erastova, V O Gershenovich, A I Malik, A Y Bartsitskaya","doi":"10.34922/AE.2025.38.5.002","DOIUrl":"https://doi.org/10.34922/AE.2025.38.5.002","url":null,"abstract":"<p><p>Medical advances of the 20th-21st centuries have led to an unprecedented increase in life expectancy, giving rise to the phenomenon of global demographic aging. Yet this triumph is overshadowed by a new monumental challenge: ensuring not just long, but high-quality, active, and independent living in old age. Traditional healthcare models, primarily focused on treating acute conditions, prove inadequate in addressing age-related challenges - frailty, sarcopenia, multimorbidity, and cognitive decline - which lead to loss of functional autonomy. In this context, geriatric rehabilitation is undergoing a radical transformation. It is no longer merely a specialized «after-the-fact» service but is emerging as a cornerstone of healthy aging strategies. Its new mission is to sustain physical, cognitive, and social functioning for as long as possible, preventing or delaying dependency. This review examines the key modern trends and cutting-edge innovations shaping the future of geriatric rehabilitation - from digital technologies and personalized approaches to preventive strategies and integrated care systems.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 5","pages":"647-654"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147487405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Researching happiness and life satisfaction of the older adults: Results from bibliometric network analysis.]","authors":"I A Pavlova","doi":"10.34922/AE.2025.38.5.013","DOIUrl":"https://doi.org/10.34922/AE.2025.38.5.013","url":null,"abstract":"<p><p>The senior age group has become a focal point in interdisciplinary studies, with increasing attention on healthy and active aging, including happiness and life satisfaction in later life. This study presents the results of a bibliometric network analysis of scientific literature exploring the happiness of older adults. Relying on R.Veenhoven's concept of overall happiness, the study distinguishes between two strands of literature: happiness and life satisfaction. While these concepts are similar in their theoretical definitions, they yet differ in practical research approaches and empirical implications. This study aims at mapping the knowledge structure for these fields, analyzing keywords and constructing co-occurrence networks, as well as examining the most influential articles and popular publication sources. The results confirm the difference in research topics on happiness and life satisfaction among older people. Studies on happiness related to the senior age group are predominantly associated with the field of psychology, whereas life satisfaction research is more closely linked to aspects of quality of life.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 5","pages":"734-744"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147487463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Chronobiotics as potential geroprotectors.]","authors":"I A Solovev, D A Golubev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article analyses the impact of chronobiotics on aging processes and their potential role in geroprotection. Key mechanisms of circadian regulation and their association with age-related diseases, including neurodegenerative and metabolic disorders, are examined. Based on existing scientific data, promising chronobiotics such as melatonin, resveratrol, and their analogs are analysed in terms of their alignment with geroprotector criteria. The main challenges in implementing chronobiotics in clinical practice, including individual chronotypes, genetic factors, and the lack of standardized application protocols, are discussed. In conclusion, promising research directions and recommendations for integrating chronobiotics into healthy aging strategies are proposed.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 3","pages":"371-379"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between depression syndromе and functional disorders in elderly residents of the European North of Russia.]","authors":"A N Galushin, L V Poskotinova, E A Krieger, O A Kharkova, E V Krivonogova, O V Krivonogova, R N Zelentsov, A A Moiseeva, I A Novikova, A V Kudryavtsev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Depression syndrome is one of the most common syndromes among the elderly and is directly associated with functional independence and quality of life. This study aimed to investigate the association between the severity of depression syndrome and functional disorders among individuals aged 60 to 74 years. In 2023, a cross-sectional study was conducted on arandom-samplein Arkhangelsk (n=611). Participants were examined for depression syndrome using the Beck Depression Scale. Functional disorders were evaluated using hand dynamometry, the Short Physical Performance Battery, the Montreal Cognitive Assessment, visual and hearing acuity tests. Zero-inflated negative binomial regression was used to analyze the associations between the severity of depression syndrome and functional disorders. After adjustment for age, education, marital status, financial difficulties, low physical activity, and all functional disorders, higher depression syndrome severity was associated with preasthenia gravis (an early stage of frailty) in both men and women and with hearing loss in women only. These findings underscore the importance of taking a gender-sensitive approach to screening for and preventing depression syndrome in older adults, especially those with complex age-related functional disorders.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 4","pages":"528-538"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Projectional anatomy of the kidneys in older age groups: comparative analysis of somatotypes.]","authors":"Y K Delalov, I U Vagabov, H M Bataev, K A Abduvosidov, Y V Dovgyallo, E S Kafarov, S T Huseynova, I N Yashina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the study was to conduct a comparative analysis of the projection anatomy of the kidneys in older individuals of various somatotypes with the determination of morphometric patterns and topographic and anatomical features to optimize diagnostic and therapeutic measures in geriatric practice. The study was carried out in accordance with the design of a one-stage cross-sectional study with a prospective recruitment of 516 participants aged 45-59 years. Somatotyping was carried out using the modified Heath-Carter method with a comprehensive assessment of endomorphy, mesomorphy and ectomorphy. The main visualization method was multispiral computed tomography with a slice thickness of 0,625-1,25 mm in native mode and with contrast enhancement. For a detailed analysis, specialized 3D Slicer software with automatic segmentation of the renal parenchyma and construction of three-dimensional models was used. Statistical analysis was performed using parametric and nonparametric methods depending on the nature of the data distribution. The results demonstrated statistically significant differences in the projection anatomy of the kidneys between somatotypes. The endomorphic type was characterized by maximum values of the angles of inclination of the renal axis with an average of 10,4±3,2° and a pronounced tendency towards age-related prolapse of the organ. The ectomorphic type demonstrated the greatest stability of anatomical relationships with minimum deviation angles of 7,8±1,9°. Progressive age-related dynamics of the angular parameters of the inclination of the renal axis was established with an increase in average values from 8,3±2,1° in mature age to 11,2±3,4° in old age. Significant gender differences in the nature of age-related changes were revealed with greater stability of morphometric parameters in men and more pronounced age-related transformation in women. The established morphometric patterns substantiate the need to take into account somatotypical features when interpreting radiation diagnostic data and planning surgical interventions in patients of older age groups. The results obtained can serve as a basis for developing personalized approaches to the diagnosis and treatment of urinary system diseases, taking into account the individual typological characteristics of the body.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 4","pages":"553-561"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The extracellular matrix of senescent stromal cells decreased secretion of SDF-1 and HGF by endothelium.]","authors":"D K Matveeva, D N Kashirina, A Y Ratushnyy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The process of mesenchymal stromal cells (MSCs) senescence is accompanied by alterations in their extracellular matrix (ECM), which has the potential to compromise cellular interactions within the perivascular niche. In this study, the effect of the ECM of senescent MSCs obtained in a «stress-induced model» on the paracrine activity of endothelial cells (ECs) in vitro was investigated. Senescent MSCs exhibited reduced production of structural and adhesive ECM proteins (including type I collagens, fibulins, perlecan, et al.) and increased deposition of senescence-associated molecules (PAI-1, GDF-15). When ECs were cultured on decellularized ECM of senescent MSCs, a significant decrease in the secretion of angiogenic and chemoattractant factors (SDF-1, HGF) was observed compared to young ECM. These findings highlight a potential role of ECM-mediated mechanisms in the development of age-related vascular pathologies and may provide a foundation for the design of anti-senescent therapeutic strategies.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 4","pages":"595-604"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Inflamaging in elderly patients with sarcopenic obesity.]","authors":"O A Osipova, E V Gosteva, S Y Popov, P G Osipov, M A Kuptsov, N I Klyushnikov, Y A Mezentsev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the study was to investigate the relationship between C-reactive protein (C-RP), platelet-to-lymphocyte ratio (PLR), and the presence of sarcopenic obesity (SO) among elderly patients. Out of 380 elderly participants, 46 had SO, accounting for 12,1% of those examined. Of these, 69,6% were female and 30,4% were male. The comparison group included 52 elderly individuals without SO. Patients with SO were more likely to experience chronic non-communicable diseases, reduced physical activity, falls, cognitive impairments such as age-related memory loss, smoke more frequently, and drink alcohol less frequently. A significant increase in PLR and CRP values was associated with the SO status. A strong correlation between PLR and CRP indices was found (p=0,735, p<0,001). CRP had a negative association with muscle mass, walking speed, hand compression strength, and overall performance. The PLR index also had a negative correlation with these variables. A positive relationship was found between pbf and both CRP and PLR. ROC analysis allowed us to identify the PLR index as a predictor of SO with an AUC of 0,862 and a threshold value of 217. The sensitivity of the model was 86,4% and the specificity was 88,5%. The diagnostic effectiveness was 87,5%. Therefore, the PLR index can serve as an accessible marker for identifying elderly patients at high risk of SO when combined with CRP assessment.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 4","pages":"503-509"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Influence of phytocomposition with nootropic properties on the quality of life and psychoemotional state of middle-age and early elderly people.]","authors":"O V Filatova, D D Mamyshev, E I Romashko, I Y Voronina, N A Shishkina, E V Kutseva, R I Khalimov, D N Sherbakov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The use of nootropic drugs is one of the approaches to improving the mental health of older people and preventing at least some cognitive disorders. The study participants were volunteers - conditionally healthy individuals. Volunteers (n=35, average age 53,4±1,21 years) took the phytocomposition «Memoris» 1 capsule 2 times a day for two weeks. Participants in the comparison group (n=35, average age 53,8±1,12 years) received a placebo (maltodextrin). The severity of anxiety/depression was assessed using the HADS questionnaire. A specialized questionnaire to determine well-being, activity, mood was used to assess the psychosomatic state. The quality of life was studied using the standardized SF-36 questionnaire. Under the influence of the phytocomposition «Memoris» statistically significantly decreased the results on anxiety scale (from 7,4±0,64 to 5,7±0,56 points, p<0,001) and depression scale (from 5,9±0,52 to 4,4±0,46 points, p<0,001), increased the results on well-being scale (from 4,9±0,19 to 5,5±0,16 points, p<0,001), as well as mood scale (from 5,5±0,16 to 5,8±0,16 points, p=0,009). After taking the phytocomposition «Memoris» an increase in scores was registered in all categories of the SF-36 questionnaire. Thus, the obtained results indicate a positive effect of the phytocomposition «Memoris» on the indicators of anxiety and depression, well-being, mood and a significant increase in the quality of life of respondents.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Method of treating obesity in elderly and senile patients (1st stage).]","authors":"D N Bobunov, E O Bilyk, Y O Dudar, T P Zavyalova, E V Vaganova, A V Dolba, D M Gebekova, A R Protsenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the work is to evaluate the efficiency of the method of treating obesity in elderly and senile patients. The patients were offered 2 nutrition programs, one based on the obtained data (insulin resistance, biliary dyskinesia, type 2 diabetes, etc.) and the final diagnosis in connection with the concomitant disease, and the second based on their taste preferences. The peculiarity of the development of the dietary program was to prepare a menu based on lean body mass, and not the total mass obtained from the results of bioimpedancemetry. The ratio of proteins, fats and carbohydrates (in grams per kg of lean body mass is 1:1:2(3). Based on stress echo and lactate testing, a program of dosed aerobic physical activity was developed for the patient. Training was carried out 3-4 times a week after the last meal, the training time was 90 minutes with the required heart rate (not higher than aerobic threshold). Against the background of using the proposed technique, a reliable decrease in total body mass, body fat mass, total water was observed according to the results of bioimpedancemetry. Also, a reliable decrease in blood parameters: ALT, AST, gamma-GT, glucose, insulin, leptin, an increase in the level of vitamin D. Thus, the selection of a personalized diet in combination with dosed aerobic physical activity and regular monitoring using heart rate monitors will not only reduce weight, but also improve health indicators (reduce weight due to adipose tissue, reduce insulin resistance, increase vitamin D levels, reduce blood pressure, liver transaminases, glucose), and also increase the effectiveness of therapeutic measures for obesity, preventing the progression of complications.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"28-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Preservation of elderly people cognitive abilities by means of physical culture.]","authors":"G I Semenova, I V Erkomaishvili, A V Lysenko, D S Lysenko, L M Dmitrenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of distance learning using a modified Pilates system on cognitive abilities and quality of life of the third age people was studied. The set of exercises proposed by the authors contributed to a reliable increase in the indicators of physical, social, intellectual and emotional health, and the psychological status of the experimental group of non-working pensioners. The distance format of combined optimization of the motor regime and correction of cognitive abilities can be recommended to ensure systematic training at any time of the year and in any weather, which is critically important for the age group studied.</p>","PeriodicalId":35293,"journal":{"name":"Advances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo","volume":"38 1","pages":"112-117"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}