Journal of Colloid and Interface Science最新文献

{"title":"Hard carbon with tailored microstructure via thermal regulation for high-efficiency sodium-ion batteries","authors":"Pengcheng Mao ,&nbsp;Jie Di ,&nbsp;Yuqi Liu ,&nbsp;Jingjing Chen ,&nbsp;Xiang Li ,&nbsp;Jie Liu ,&nbsp;Wenbin Hu ,&nbsp;Cheng Zhong","doi":"10.1016/j.jcis.2026.140026","DOIUrl":"10.1016/j.jcis.2026.140026","url":null,"abstract":"<div><div>Hard carbon (HC) is the most promising commercially available anode material for sodium-ion batteries (SIBs) due to the high specific capacity, low operation voltage and low cost. However, HC faces the problems of poor initial Coulombic efficiency (ICE) and ambiguous sodium storage mechanism. Furthermore, the relationship between solid electrolyte interphase (SEI) characteristics, particularly its chemical composition and microstructural features, and electrochemical performance remains poorly understood. To this end, HC with abundant closed pores and adjustable defect concentration was prepared in this study using cheap pine bark as raw material through precise thermal regulation. At high pyrolysis temperature, the carbon layer in HC fully grows and promotes the growth of closed pore. The optimized PHC-1300 exhibits a high ICE of 89.6% and an outstanding specific capacity of 347.62 mAh g⁻¹ at 0.1C. Moreover, the PHC-1300//Na₃V₂ (PO₄)₃ full-cells also exhibit excellent cycling performance. Based on the electrochemical performance and microstructure of the pine bark-based HC, it is proposed that the sodium storage mechanism is “adsorption-intercalation-filling”. Notably, it is found that the HC surface with suitable defect concentration can induce the formation of fluorine-rich organic SEI phase, which is beneficial to maintain the interfacial stable to improve the cycling stability.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 140026"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146123331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailorable MoS2 quantum dots nanofluids via coordination-confined growth for high-performance lubrication","authors":"Ru Yan,&nbsp;Hongyang Wang,&nbsp;Rui Dong,&nbsp;Ping Wen,&nbsp;Mingjin Fan","doi":"10.1016/j.jcis.2026.140049","DOIUrl":"10.1016/j.jcis.2026.140049","url":null,"abstract":"<div><div>Conventional solvent-free nanofluids hold promise as lubricants but often face challenges in intricate preparation and unadjustable performance. Herein, we developed a facile one-pot strategy for synthesizing MoS₂ quantum dots (QDs) nanofluids (MoNFs) <em>via</em> a coordination-confined growth approach, which features cyan-fluorescent with an average size of 3.8 nm, homogeneously dispersed in a tailored ionic liquid matrix. The resulting MoNFs exhibit tunable viscosity and desirable shear-thinning behavior. When evaluated as lubricants, the optimal formulation (3MoNFs) decreases wear volume by 73.8% compared to the base fluid. Comprehensive characterization of worn track reveals a triplex synergistic lubrication integrating an electric-double-layer film, tribochemical reaction film and solid-like nanofluid layer, concurrently assisted with repairing pre-existing wear scars. Impressively, blending merely 0.7 wt% 3MoNFs into commercial SN 0 W-30 engine oil enhances its anti-wear performance by 47.5%, demonstrating outstanding potential for high-performance lubricants.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 140049"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146130757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure–property relationships in saccharide-derived carbon dots: Tuning oxygen functionalities and sp2 domains for antioxidant performance","authors":"Agung Wibowo ,&nbsp;Mohd Jahir Khan ,&nbsp;Sopanat Sawatdee ,&nbsp;Warangkana Pornputthapitak ,&nbsp;Soontorn Tuntithavornwat ,&nbsp;Atthapon Srifa ,&nbsp;Pattaraporn Posoknistakul ,&nbsp;Soraya Pornsuwan ,&nbsp;Navadol Laosiripojana ,&nbsp;Yijiao Jiang ,&nbsp;Kanokwan Sansanaphongpricha ,&nbsp;Chularat Sakdaronnarong","doi":"10.1016/j.jcis.2026.139939","DOIUrl":"10.1016/j.jcis.2026.139939","url":null,"abstract":"<div><div>Excessive reactive oxygen species (ROS) drive oxidative stress and disease progression, yet the structural determinants of antioxidant activity in carbon dots (CDs) remain unclear. In this study, the influence of oxygenated surface functional groups and carbon hybridization states on the performance of saccharide-derived CDs was elucidated. CDs were synthesized from five saccharide precursors via hydrothermal carbonization, and synthesis parameters were systematically optimized using response surface methodology combined with central composite design (200–240 °C, 6–12 h). Among the tested precursors, xylose yielded CDs (X-CDs) with the smallest size (2.17–4.38 nm), the strongest blue emission (427–450 nm), the highest negative surface charge (−38.5 to −84.6 mV), and the highest quantum yield (0.80–2.81%). Spectroscopic analyses revealed enriched oxygen functionalities (O/C ratio up to 0.32) and graphitic sp² domains with reduced sp³ content, correlating with enhanced electronic delocalization. Optimized X-CDs exhibited potent radical scavenging activity (EC₅₀ = 0.047 mg/mL for DPPH; 0.008 mg/mL for ABTS) while showing low cytotoxicity toward normal and cancer cells. These findings establish a mechanistic framework linking oxygenated groups and sp² hybridization to enhanced antioxidant properties and provide a green, tunable strategy for designing high-performance CDs from renewable precursors for biomedical, nutraceutical, and environmental applications.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 139939"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146130750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-redox cycling driven charge transfer in CuxO/CeO2 heterojunction for photocatalytic activation of peroxymonosulfate toward tetracycline degradation","authors":"Huijie Wang ,&nbsp;Jiaxin Li ,&nbsp;Zixiang Jiao ,&nbsp;Xiaodan Zheng ,&nbsp;Wei Ma ,&nbsp;Kesheng Cao ,&nbsp;Lingwei Xue ,&nbsp;Fu Xu ,&nbsp;Yang Wan ,&nbsp;Yangyang Yang ,&nbsp;Binrong Li ,&nbsp;Pengwei Huo","doi":"10.1016/j.jcis.2026.139996","DOIUrl":"10.1016/j.jcis.2026.139996","url":null,"abstract":"<div><div>The efficient removal of antibiotic residues such as tetracycline (TC) from water remains challenging. Research has demonstrated that heterogeneous systems utilizing photocatalysis to activate peroxymonosulfate (PMS) exhibit exceptional performance. However, preparing materials with strong charge transfer capabilities and stability still poses certain challenges. This study developed a Cu_xO/CeO₂ heterojunction composite with abundant oxygen vacancies (O_V) for visible-light-driven activation of peroxymonosulfate (PMS). The hierarchical flower-sphere structure of CeO₂ provides ample adsorption sites and mass transfer channels, while the synergy between the heterojunction interface and the dual redox cycles of Cu⁺/Cu²⁺ and Ce³⁺/Ce⁴⁺ significantly enhances visible-light absorption and accelerates the separation and transfer of photogenerated carriers. Femtosecond transient absorption (fs-TA) spectroscopy further confirms that the formation of the heterojunction effectively regulates the direction of carrier transfer and prolongs the charge lifetime. Density functional theory (DFT) calculations reveal that O_V markedly promote the adsorption and activation of PMS. Under visible light irradiation, the system achieves a TC degradation efficiency of 99.2% within 60 min, primarily driven by sulfate radicals (SO₄^•−) and hydroxyl radicals (•OH), with the intermediates exhibiting generally low toxicity. In addition, in-situ infrared spectroscopy (in-situ FT-IR) further confirmed the outstanding TC adsorption capacity and degradation activity of the Cu_xO/CeO₂ heterojunction composite. This work provides insightful perspectives for designing efficient and stable heterojunction catalysts through defect and interface engineering for water purification.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 139996"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macropore engineering of MOF-derived carbon for superior microwave absorption","authors":"Zi Wang ,&nbsp;Junru Yao ,&nbsp;Jinlong Lv ,&nbsp;Yang Cao ,&nbsp;Biao Lv ,&nbsp;MinJie Liang ,&nbsp;Honghong Zhao ,&nbsp;Youyi Sun","doi":"10.1016/j.jcis.2026.139993","DOIUrl":"10.1016/j.jcis.2026.139993","url":null,"abstract":"<div><div>Regulating electromagnetic pollution has become significance as 5G communication and radar technologies rapidly progress. This study proposes a macroporous engineering method utilizing polystyrene microsphere templates to address the limitations of single pore size structure and the difficulties in achieving impedance matching and loss capability in traditional carbon materials derived from metal-organic frameworks (MOFs). Co-Zn-C/C composite materials with a multi-level pore structure have been successfully synthesized. Through meticulous regulation of the PS template's dimensions via PVP dosage modifications, Metal-organic framework-on-Metal-organic framework (MOF-on-MOF) epitaxial growth, and a high-temperature carbonization of ZIF-8/ZIF-67, a composite material featuring a multi-level pore architecture (macropore mesoporous carbon nanotube network) and tunable pore size was synthesized. The results indicate that the material contains uniformly dispersed Co nanoparticles, a substantial specific surface area, and many nitrogen-doped defects. The optimized CZCC-2 sample demonstrates superior impedance matching and multi-mechanism synergistic attenuation, achieving an effective absorption bandwidth of 6.59 GHz at a thickness of 2.1 mm and a minimum reflection loss of −59.48 dB at 9 GHz at 3.0 mm, as per electromagnetic performance testing. The exceptional capability for suppressing electromagnetic wave scattering in practical applications is further validated by finite element modeling and radar cross-section (RCS) analysis. This paper presents innovative methods for developing absorbent materials that are thin, lightweight, broadband, high-intensity.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 139993"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Halloysite nanotubes interacting with lipid vesicle membranes","authors":"Chiara Ferlito ,&nbsp;Lorenzo Lisuzzo ,&nbsp;Giuseppe Lazzara ,&nbsp;Marc Schmutz ,&nbsp;Antonio Stocco","doi":"10.1016/j.jcis.2026.140013","DOIUrl":"10.1016/j.jcis.2026.140013","url":null,"abstract":"<div><div>Halloysite nanotubes (HNTs), naturally occurring aluminosilicates with a tubular structure, are promising nanocarriers for drug delivery due to their biocompatibility and unique morphology. However, their interaction with lipid membranes remains not fully explored. In this work, we aim at elucidating on the adhesion of HNTs on unilamellar vesicles made of phospholipids used as model of biological membranes. The adhesion was modulated by varying the lipid composition, ionic strength, and the size ratio between HNTs and vesicles. The adhesion mechanism was also studied by trapping a single HNT with optical tweezers and let it interact with a single vesicle. These findings show a preferential adhesion of the HNT tip on the lipid bilayer, which represents an important step toward directional membrane targeting in biomedical applications.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 140013"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146103083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guided electron flow in anthraquinone-methoxy donor-acceptor1-acceptor2 covalent triazine frameworks enabling superior selective uranium capture","authors":"Ruoxuan Guo,&nbsp;Liping Song,&nbsp;Wencheng Yao,&nbsp;Yingzhong Huo,&nbsp;Lu Wang,&nbsp;Yang Liu,&nbsp;Yuejie Ai,&nbsp;Xiangke Wang","doi":"10.1016/j.jcis.2026.140012","DOIUrl":"10.1016/j.jcis.2026.140012","url":null,"abstract":"<div><div>Rational design and synthesis of stable and efficient photocatalysts for selective U(VI) capture in water remains a great challenge due to the complicated water environment. Herein, considering the synergistic interaction between anthraquinone (−AQ, electron acceptor) and methoxy (–OCH₃, electron donor), a series of ternary donor-acceptor-acceptor (D-A1-A2) covalent triazine frameworks named as OCH₃(x)-AQ(y) (x and y represent different content ratios) were rationally designed and synthesized via molecular regulation. This work not only constructed a directional charge-transfer pathway, but also greatly improved the utilization efficiency of photogenerated electrons in OCH₃(x)-AQ(y) framework, which was also further verified by density functional theory (DFT) calculations. Finally, OCH₃(2)-AQ(3) could reach nearly 100% removal efficiency of U(VI) within 240 min under visible light irradiation in air. Meanwhile, OCH₃(2)-AQ(3) showed an extremely high distribution coefficient (K_d, 1.07 × 10⁶ mL·g⁻¹) for U(VI) under multicomponent ion competition and further performed high removal efficiencies (&gt;98%) in real water environments, such as seawater and groundwater. Importantly, the machine learning results also demonstrated that the structural characteristics would greatly influence the catalytic performance of CTF catalysts. The component tuning of donor-acceptor groups achieved synergistic effects in stepwise charge transport and target-selective site accessibility, which offered an effective photocatalytic strategy for U(VI) extraction in complex water environment.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 140012"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engineered hollow cubic structures CoS/NiS heterojunctions enable high-performance magnesium-ion batteries","authors":"Runjing Xu ,&nbsp;Han Xiao ,&nbsp;Yuan Fang ,&nbsp;Ya Chen ,&nbsp;Pengfei Zhang ,&nbsp;Kailin Li ,&nbsp;Yuxuan Li ,&nbsp;Huinan Yu ,&nbsp;Jiayun Zhang ,&nbsp;Chaoxin Wu ,&nbsp;Xin Gao ,&nbsp;Tao Meng ,&nbsp;Xiaodong Chen ,&nbsp;Lifeng Cui","doi":"10.1016/j.jcis.2026.139992","DOIUrl":"10.1016/j.jcis.2026.139992","url":null,"abstract":"<div><div>Rechargeable magnesium-ion batteries (RMBs) demonstrate notable benefits, including higher theoretical energy density, cost-effectiveness, and improved safety characteristics, positioning them as a viable substitute for conventional energy storage solutions. Nevertheless, the ongoing development of high-performance RMBs continues to face inevitable challenges, such as unsatisfactory practical capacity, inadequate cycle durability, swift energy degradation, and a comparatively limited-service life. Herein, CoS/NiS nanomaterials with cubic-shaped morphology were prepared by a two-step metal sulfide template-free solvothermal synthesis method. The material with internal cavity structure effectively mitigates the large expansion of magnesium-ion battery cathode material due to Mg²⁺ embedding during the charging and discharging process, and provides a robustness electrode-electrolyte interface, thus greatly improving the cycle life. Besides, the introduction of Ni elements into CoS materials may form heterojunctions thereby lowering the potential barrier of the conversion reaction and improving the reaction kinetics and redox reversibility. In addition, the abundance of highly electronegative S<img>S bonds in the CoS/NiS material, which also provides many electrochemically active sites and smooth transport paths for the embedding of Mg²⁺, leads to the reduction of its polarization and the improvement of its reaction kinetics, which makes the CoS/NiS as a RMBs cathode material with a high specific capacity and a long cycling life. Thus, this research presents a feasible and effective strategy for enhancing the Mg²⁺ storage capability of engineered CoS nanomaterials, with potential applicability and adaptability to other electrode materials.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 139992"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Light-driven host-guest supramolecular transport engineering an antibacterial trap switch","authors":"Xuejiao Wang ,&nbsp;Zhi Su ,&nbsp;Lan Zheng ,&nbsp;Kaifa Zhao ,&nbsp;Qiyang Cai ,&nbsp;Xiangyu Wei ,&nbsp;Yaqing Zhao ,&nbsp;Yan Ke ,&nbsp;Yuelu Fan ,&nbsp;Hu Zhu","doi":"10.1016/j.jcis.2026.139982","DOIUrl":"10.1016/j.jcis.2026.139982","url":null,"abstract":"<div><div>Inspired by nature's sophisticated use of light energy, we report a bioinspired antibacterial trap switch operating without exogenous competitors. This work engineers a light-gated supramolecular system where host-guest conformational reorganization between cucurbit[8]uril (CB[8]) and dicationic symmetric azobenzene derivative (Azo-<em>E</em>) enables precise control over antimicrobial agent release. Upon ultraviolet (UV) irradiation triggers <em>E</em>-<em>Z</em> isomerization, enhancing its binding affinity to CB[8] and resulting in steric displacement of the encapsulated antibacterial agent through conformational reorganization. This system achieves &gt;99.9% bacterial eradication, supports reversible switching across four conventional antibacterial agents, and reduces mammalian cell cytotoxicity. Spray-coatable on different biomaterial surfaces, it demonstrates spatial precision for localized disinfection. This molecular engineering establishes a general platform for spatiotemporally precise regulation of bioactive cargoes, enabling adaptive supramolecular systems with infection control.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 139982"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146123299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engineered PtAgCu/MoS2 and hexagonal star-like nitrogen-doped carbon enabling highly efficient sandwich-type electrochemical immunosensing via multiple signal enhancement","authors":"Xiaofei Sun ,&nbsp;Ning Chen ,&nbsp;Shujun Wang ,&nbsp;Yushu Lin ,&nbsp;Jie Zhang ,&nbsp;Shuo Xing ,&nbsp;Qing Liu ,&nbsp;Yueyun Li ,&nbsp;Daopeng Zhang ,&nbsp;Kai Feng ,&nbsp;Jongnam Park ,&nbsp;Feng Tang","doi":"10.1016/j.jcis.2026.139984","DOIUrl":"10.1016/j.jcis.2026.139984","url":null,"abstract":"<div><div>Cardiac troponin I (cTnI), recognized as the gold-standard biomarker for acute myocardial infarction (AMI), plays a crucial role in the early diagnosis and clinical management. Herein, we present a rationally designed multiple signal enhancement strategy for an ultrasensitive electrochemical immunoassay of cTnI. This work integrates the superior catalytic activity of a wrinkled MoS₂-supported PtAgCu ternary alloy (PtAgCu/MoS₂) with the excellent conductivity of hexagonal star-like nitrogen-doped carbon (HS-NC) modified by gold nanoparticles (Au@HS-NC). The PtAgCu alloy, featuring maximized atomic utilization and optimized d-orbital coupling, exhibits outstanding hydrogen peroxide (H₂O₂) electroreduction activity and a large electrochemically active surface area, thereby effectively amplifying the sensing signal. Meanwhile, the precisely designed MoS₂ carrier not only offers abundant anchoring sites and facilitates charge transfer but also enriches H₂O₂ reactant, thereby promoting the catalytic performance of the PtAgCu alloy. Furthermore, as an ideal substrate, the morphologically engineered HS-NC, enriched with nitrogen functionalities, offers a highly conductive framework with ultralarge surface area (1121.80 m² g⁻¹), enabling efficient immobilization of primary antibodies (Ab₁) and stable, accelerated charge transfer, thereby synergistically amplifies the signal output. Benefiting from this multiple amplification strategy, the proposed immunosensor achieves a remarkably low limit of detection of 0.51 fg mL⁻¹, and an exceptionally broad dynamic range (from 10 fg mL⁻¹ to 100 ng mL⁻¹), while exhibits excellent selectivity in complex matrices, maintaining high reproducibility and stability. This work demonstrates a rational multi-amplification design paradigm for constructing high-performance immunosensors and highlights its promising application in AMI early diagnosis.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"710 ","pages":"Article 139984"},"PeriodicalIF":9.7,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}