Journal of Colloid and Interface Science最新文献

{"title":"Designing multifunctional artificial SEI layers for long-term stability of sodium metal anodes.","authors":"Wenwu Mo, Shaojie Hu, Huanyu Li, Xiaowei Zhu, Lijuan Zhang","doi":"10.1016/j.jcis.2024.12.100","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.100","url":null,"abstract":"<p><p>Sodium metal batteries, which are low-cost and have great potential for large-scale energy storage, face challenges such as shortened battery life and safety issues due to the uncontrolled growth of sodium dendrites and extensive side reactions during the cycling of sodium metal anodes. In this work, we address these challenges by introducing SnF₂ to the surface of the sodium metal, which in situ generates a stable composite interfacial layer (NaSn@NaF). This interfacial layer contains Na-Sn alloy with a potential gradient and electrically insulating NaF, which promotes uniform deposition of Na⁺ ions and effectively suppresses dendrite formation and side reactions. Additionally, In addition, the average Young's modulus of the modified artificial solid electrolyte interface layer (SEI) is about 6.9 Gpa, which is about 2.7 times higher than that of bare sodium (2.4GPa). This artificial/natural composite interfacial layer significantly enhances the performance of sodium electrodes. Symmetric battery cycling tests demonstrated that the electrode with the composite interfacial layer could sustain continuous charging and discharging for 870 h, a significant improvement compared to the 95 h achieved by the pristine sodium metal anode. Furthermore, the full-cell configuration (Na|NaSn@NaF||NVP) exhibited remarkable long-cycle stability, maintaining around 80 % capacity retention after 1100 cycles at a 2C rate, with minimal capacity degradation. This research presents a straightforward and efficient method that enhances the practical application potential of sodium metal anodes.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"600-609"},"PeriodicalIF":9.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing cobalt-nickel dual-atoms on boron, nitrogen-codoped carbon nanotubes for carbon dioxide electroreduction to syngas.","authors":"Dan Ping, Yapeng Li, Shide Wu, Zhiqiang Zhang, Weitao Liu, Dingsheng Wang, Shuqing Liu, Shiwen Wang, Xuzhao Yang, Guanglu Han, Junfeng Tian, Dongjie Guo, Huajun Qiu, Shaoming Fang","doi":"10.1016/j.jcis.2024.12.096","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.096","url":null,"abstract":"<p><p>Developing highly efficient electrocatalysts to produce syngas with a stable hydrogen/carbon monoxide (H₂/CO) ratio in a wide potential window via electrochemical carbon dioxide (CO₂) reduction is desperately required but still challenging. Herein, a dual-atomic site on boron, nitrogen-codoped carbon nanotubes (BCN) has been designed, containing both cobalt (CoN₅) and nickel (NiN₃B₂) sites. Benefiting from the structure advantage and the bifunctional Co/Ni sites, such designed catalyst (CoNi-BCN) demonstrates remarkable performance for syngas production, achieving a stable H₂/CO ratio of 1.5 over a broad potential window from -0.47 to -0.87 V vs. RHE. By tuning the Co/Ni molar ratio in CoNi-BCN, the H₂/CO ratio can be adjusted from 0.5 to 2. In addition, this electrocatalyst exhibits outstanding stability within a long-term 20 h electrolyzing. Both experimental and theoretical calculation results confirm the primary role of the Co sites in H₂ production and the Ni sites in CO production, as well as the preferred process for H₂ evolution. This work provides a strategy in the construction of dual-site catalysts for efficient syngas production, which is significant for practical applications.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"446-456"},"PeriodicalIF":9.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrophilic/hydrophobic heterojunctions for enhanced photocatalytic hydrogen evolution via gas release dynamics.","authors":"Xiaoli Fan, Xin Song, Jingxue Sun, Yangpeng Zhang, Zhonghua Li","doi":"10.1016/j.jcis.2024.12.095","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.095","url":null,"abstract":"<p><p>Covalent-organic frameworks (COFs), characterized by their exceptional light absorption and ordered architecture, have emerged as potential candidates for photocatalytic hydrogen production. In this work, we discovered that the incorporation of fluorine into the sub-nanocavity of azine-linked COF (TF-COF) not only augments its hydrophobicity but also strengthens the interaction between Pt cocatalysts and COFs. In an effort to enhance photocatalytic water splitting efficiency, we integrated the hydrophobic TF-COF with the hydrophilic carbon nitride (CN) to construct a hydrophilic/hydrophobic heterojunction (CTF-x heterojunction). Both experimental results and density functional theory (DFT) calculations reveal that the hydrophilic side, CN, aids in the adsorption and transfer of water molecules, whereas the hydrophobic side, TF-COF, generates hydrogen and promotes its overflow, thereby achieving space charge separation. The hydrogen evolution activity of CTF-50 % (with a CN content of 50 %) reached an optimal value of 2428 μmol g^-1h^-1_, with an apparent quantum yield (AQY) of 2.6 % at 400 nm. This is approximately four times higher than that of pure CN and ten times greater than that of TF-COF. We believe this work will provide valuable insights for developing efficient heterojunction photocatalysts.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"531-541"},"PeriodicalIF":9.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Charge transport channel and nonmetallic plasmon synergistically augment surface reaction kinetics and charge separation for efficient photoelectrochemical hydrogen evolution of CdS/TiN-sensitized Fe₂V₄O₁₃ photoanode.","authors":"Zhiyuan Zheng, Canqun Sun, Mengjie Ma, Tianqi Wang, Lijuan Wang, Junli Fu, Qing Zhou, Yujie Liang, Wenzhong Wang","doi":"10.1016/j.jcis.2024.12.090","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.090","url":null,"abstract":"<p><p>Achieving simultaneous enhancement in the light energy utilization efficiency, bulk charge carrier separation and surface charge carrier injection efficiency as well as the surface reaction kinetics of water oxidation is a formidable challenge for photoanodes in photoelectrochemical (PEC) water splitting hydrogen generation. Herein, nanoparticle-assembled flower-like CdS spheres and nonmetallic plasmonic TiN nanoparticles are exploited to successively sensitize Fe₂V₄O₁₃ nanoporous film (NPF) photoanode for achieving efficient PEC hydrogen evolution. The sensitization of TiN and CdS simultaneously integrates type-II band structure, surface plasmon resonance and Schottky junction into Fe₂V₄O₁₃ NPF photoanode, synergistically achieving simultaneous enhancement in the light energy utilization efficiency, bulk charge carrier separation efficiency, surface reaction kinetics of water oxidation and surface charge carrier injection efficiency. As a result, the highest charge separation and injection efficiencies of CdS/TiN-sensitized Fe₂V₄O₁₃ NPF photoanode are respectively increased by 25.5 and 1.96 times to those of bare Fe₂V₄O₁₃ NPF photoanode. Furthermore, the designed and constructed CdS/TiN-sensitized Fe₂V₄O₁₃ NPF photoanode exhibits substantially boosted unbiased solar-light-driven PEC hydrogen evolution ability with a photocurrent density of 2.12 mA/cm², which is two orders of magnitude (662 times) higher than that of the unsensitized Fe₂V₄O₁₃ NPF photoanode. The findings in this work provide a novel and promising strategy to design and construct high-performance Fe₂V₄O₁₃-based nonmetallic plasmonic photoanodes for potential application in PEC hydrogen evolution.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"585-599"},"PeriodicalIF":9.4,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Responsive boronate ester lipid nanoparticles for enhanced delivery of veliparib and platinum (IV) prodrug in chemotherapy.","authors":"Wanyue Xiao, Rui Geng, Duohang Bi, Yufeng Sun, Zhilang Li, Yijing Liu, Jintao Zhu","doi":"10.1016/j.jcis.2024.12.081","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.081","url":null,"abstract":"<p><p>The chemotherapeutic effectiveness of breast cancer treatment is currently unsatisfactory due to inadequate drug delivery, suboptimal drug release, and drug inactivation. Herein, we present an innovative boronate ester lipid nanoformulation to improve the delivery of a platinum (IV) prodrug (Pt-C12) and veliparib (Veli), aiming to increase their therapeutic efficacy through a synergistic effect. We identify the optimal ratio of Pt-C12 to Veli for achieving synergy in vitro, followed by the encapsulation of Pt-C12 and Veli in lipid nanoparticles (NPs) incorporating responsive boronate ester lipids (LPC-PPE) to produce responsive lipid NPs (LPV NPs). These LPV NPs demonstrate high sensitivity to low levels of hydrogen peroxide (H₂O₂), enabling efficient drug release. In contrast, the nonresponsive lipid NP (DPV NP) control shows minimal responsiveness to H₂O₂. Furthermore, acidic tumor microenvironments trigger phenylboronic acid (PBA) generation from LPC-PPE in the LPV NPs. Compared with DPV NPs, the interaction between PBA on the LPV NPs and sugar components on tumor cells significantly improves LPV NP cellular uptake and lysosomal escape in vitro. Due to the enhanced cellular delivery and the synergistic drug combination, the LPV NPs induce an increase in apoptosis in 4 T1 cells compared with control groups. Moreover, the LPV NPs exhibit greater efficiency of drug delivery to tumors than the DPV NPs, and have a greater inhibitory effect on tumors than the controls. Overall, our findings highlight the potential of functional lipids and synergistic drug combinations in overcoming obstacles in breast cancer treatment and advancing the development of responsive delivery systems.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"375-386"},"PeriodicalIF":9.4,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Boosting of the piezoelectric photocatalytic performance of Bi₂MoO₆ by Fe³⁺ doping and construction S-scheme heterojunction using WO₃.","authors":"Jiamin Li, Changheng Chen, Jiangwen Bai, Yuehui Jin, Chongfeng Guo","doi":"10.1016/j.jcis.2024.12.086","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.086","url":null,"abstract":"<p><p>Although self-polarized piezoelectric semiconductor photocatalysts significantly enhance the separation of internally generated photocarriers, their photocatalytic performance is constrained by insufficient internal polarisation and a wide bandgap. Additionally, the low concentration of oxygen in contaminated water limits the effectiveness of such photocatalysts. To the best of our knowledge, this study was the first to determine that the piezoelectric properties of Bi₂MoO₆ (BMO), was due to the polarisation displacement of the MoO₆ octahedron that occurred along the x-axis, as revealed through density functional theory (DFT) calculations. Subsequently, the self-polarisation characteristics of BMO were enhanced and the bandgap was reduced through Fe³⁺ doping, as confirmed via atomic force microscopy, hysteresis loop measurements and DFT analysis, resulting in an increase in surface potential from 30.41 to 46.80 mV. Furthermore, an S-scheme WO₃/Bi₂MoO₆:Fe³⁺ heterojunction was developed to improve the surface separation of photoelectron-hole pairs. The piezoelectric photocatalytic performance of this sample was evaluated through the degradation of rhodamine B (RhB) and oxygen generation. Results indicated that the degradation rate of RhB reached 98.63 % within 25 min under the synergistic influence of light and ultrasound, which was 1.85 and 9.60 times higher than those of Bi₂MoO₆ and WO₃, respectively. Furthermore, the optimal oxygen production efficiency was 167.41 µmol·g^-1·h^-1. This study provides a novel approach for designing more efficient piezoelectric photocatalysts.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"574-584"},"PeriodicalIF":9.4,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zinc cadmium sulphide-based photoreforming of biomass-based monosaccharides to lactic acid and efficient hydrogen production.","authors":"Ermiao Liang, Ke Cheng, Xue Liu, Mingcong Xu, Sha Luo, Chunhui Ma, Zhijun Chen, Yahui Zhang, Shouxin Liu, Wei Li","doi":"10.1016/j.jcis.2024.12.082","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.082","url":null,"abstract":"<p><p>Approaches that add value to biomass through the use of photoreforming reactions offer great opportunities for the efficient use of renewable resources. Here, we constructed a novel zinc cadmium sulphide/molybdenum dioxide-molybdenum carbide-carbon (Zn_xCd_1-xS-y/MoO₂-Mo₂C-C) heterojunction which was applied to photoreforming of biomass-based monosaccharides for hydrogen and lactic acid production. Bandgap engineering effectively modulated the redox capacity of Zn_xCd_1-xS-y and exposed more (101) crystalline surfaces, which improved the lactic acid selectivity. The MoO₂-Mo₂C-C (MC) co-catalysts had unique microstructures that increased the light absorption range and the number of active sites of Zn_xCd_1-xS-y. These features effectively promoted the separation and migration of photogenerated carriers, which in turn enhanced the photoreforming activity. The optimised Zn_0.4Cd_0.6S-0/MC composites exhibited superior photocatalytic activity with a hydrogen yield of 12.2 mmol/g/h. Conversion of biomass-based monosaccharides was approximately 100 %, where xylose had the greatest lactic acid selectivity (64.1 %). Active species, including h⁺, ⋅O₂^-, ⋅OH, and ¹O₂, all favoured lactic acid production, where ⋅O₂^- played a major role in the conversion. This study demonstrates that rational design of photocatalysts can achieve the selective conversion of biomass into high value-added chemicals as well as the generation of clean energy.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"432-445"},"PeriodicalIF":9.4,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LaF₃@SiO₂ yolk-shell heterostructure nanofiber-modified separator enhances the long-cycling performance of lithium-sulfur batteries.","authors":"Yingying Bao, Bin Yue, Lin Li, Hong Shao, Yunrui Xie, Qianli Ma, Wensheng Yu, Jinxian Wang, Xiangting Dong","doi":"10.1016/j.jcis.2024.12.093","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.093","url":null,"abstract":"<p><p>High-energy-density lithium-sulfur (Li-S) cells are identified as one of the most prospective next-generation energy storage appliances owing to their numerous advantages. Nonetheless, their widespread applications are restricted by the unwanted shuttling effect and tardy conversion reaction kinetics of lithium polysulfides (LiPSs). To address these puzzles, we present an innovative strategy for the one-pot synthesis of LaF₃@SiO₂ yolk-shell heterostructure nanofibers (YSHNFs) through a straightforward uniaxial electrospinning process coupled with fluorination, avoiding the complexities of traditional methods. The specially designed LaF₃@SiO₂ YSHNFs are utilized as an interlayer to modify a polypropylene (PP) film, creating a LaF₃@SiO₂/PP separator for long-cycle Li-S batteries. Peculiar \"3 + 1\" mode anchoring (quadruplex anchoring) and \"3 + 1\" mode catalysis (quadruplex catalysis) are present in the LaF₃@SiO₂ YSHNFs, effectively inhibiting the LiPSs shuttling and enhancing their conversion reaction kinetics. Furthermore, the yolk-shell cavity acts as a nanoreactor, advancing the conversion of LiPSs on the LaF₃@SiO₂ heterostructure. Owing to the strategic design of components and the distinctive structure of LaF₃@SiO₂ YSHNFs, the combination of the quadruplex anchoring, the quadruplex catalysis, and the nanoreactor collectively contributes to a long-cyclic Li-S battery with high performances. The bare sulfur cathode using the LaF₃@SiO₂/PP separator exhibits an impressive incipient discharge capacity of 1514 mAh g^-1 at 0.2 C and displays a decay rate of only 0.034 % per cycle at 2 C over 600 cycles with a distinguished stability. Density functional theory calculations offer insights into the mechanisms of quadruplex anchoring and catalytic conversion reactions involving the LaF₃@SiO₂ heterostructure for LiPSs redox process. The strategies for interlayer design, concepts and techniques proposed in this study provide valuable guidance for developing yolk-shell structured materials for advanced long-cyclic Li-S batteries.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"358-374"},"PeriodicalIF":9.4,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electron effect regulation: A study on the influence of electron-donating and withdrawing group modification on the performance of metal-coordinated catalysts for electrochemical carbon dioxide reduction.","authors":"Jiaqi Yu, Hongsen Zhang, Qi Liu, Jing Yu, Dalei Song, Chu-An Xiong, Ying Li, Rumin Li, Jun Wang","doi":"10.1016/j.jcis.2024.12.085","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.085","url":null,"abstract":"<p><p>Electron effect regulation is a crucial factor influencing the activity and selectivity of Cu-based coordination compound catalysts in the electrochemical carbon dioxide reduction reaction (CO₂RR). Despite significant progress, the structure-activity relationship and the underlying regulatory mechanisms warrant further in-depth investigation. In this study, three types of Cu-[ONNO] tetradentate coordination molecular catalysts with varying electron densities, namely Cu-N₂O₂, methoxy-modified Cu-N₂O₂ (Cu-EDG-N₂O₂), and nitro-modified Cu-N₂O₂ (Cu-EWG-N₂O₂), were prepared using a substituent regulation strategy. The prepared catalyst's micromorphology and structural characteristics were analyzed using various characterization methods. Systematic electrocatalytic CO₂RR experiments were conducted to evaluate the performance of these catalysts. Compared to the unmodified Cu-N₂O₂, the Cu-EDG-N₂O₂ catalyst exhibited superior reduction performance for CH₄ and C₂H₄ products. At an applied potential of -1.7 V vs. the reversible hydrogen electrode, the Faradaic efficiencies for CH₄ and C₂H₄ of Cu-EDG-N₂O₂ were 37.8 ± 2.2 % and 25.0 ± 0.5 %, respectively. In contrast, the Cu-EWG-N₂O₂ catalyst demonstrated higher activity towards the production of H₂ as a by-product. The effects of electronic properties of substitutions on catalyst performance were revealed by combining experimental characterization and theoretical simulation. The results showed that the conjugation effect of the -OCH₃ group facilitates faster electron transfer between Cu and CO₂, thereby enhancing CO₂RR activity. Additionally, the introduction of different substituents modulates the local microenvironment around the Cu active centers, significantly influencing the catalytic performance. This study provides valuable theoretical and experimental insights into the design of efficient Cu-N₂O₂-type metal coordination electrocatalysts for CO₂RR processes.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"387-397"},"PeriodicalIF":9.4,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photothermally-enhanced ferroptotic-chemo therapy enabled by ZIF-derived multizyme.","authors":"Changyu Cao, Da Bao Zha, Chencheng Sun, Nan Yang, Shi Tao, Peng Jiang, Yan Ling Li, Zheye Zhang, Dong-Sheng Li, Xuejiao Song, Peng Chen, Xiaochen Dong","doi":"10.1016/j.jcis.2024.12.088","DOIUrl":"https://doi.org/10.1016/j.jcis.2024.12.088","url":null,"abstract":"<p><p>A multi-functional single-Fe-atom nanozyme (Fe-SAzyme) is designed, integrating the near-infrared photothermal property, the ability to carry chemoagent (doxorubicin - DOX), and nanocatalytic activities mimicking peroxidase, oxidase, and glutathione oxidase. The nanocatalytic activities act cooperatively to effectively produce cytotoxic radicals in the tumor microenvironment (TME), thereby leading to ferroptosis of cancer cells. The photothermal effect not only enhances the nanocatalytic therapy but also enables photothermal therapy. And release of DOX upon triggering by TME and the Fe-SAzyme activities enables chemotherapy to induce apoptosis of cancer cells. Such targeted and synergistic multi-modality treatment achieves complete tumor elimination without obvious side effects. Further, the underlying working mechanism is carefully revealed both theoretically and experimentally.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"683 Pt 1","pages":"398-407"},"PeriodicalIF":9.4,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}