Medecine des Maladies Metaboliques最新文献

{"title":"De la recommandation à la pratique : les défis de la mise en œuvre dans la prise en charge du diabète","authors":"Pierre Yves Benhamou","doi":"10.1016/j.mmm.2025.10.001","DOIUrl":"10.1016/j.mmm.2025.10.001","url":null,"abstract":"","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 8","pages":"Pages 591-592"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145693208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prise de position du GCC-CSO sur les traitements médicamenteux de l’obésité (TMO) chez l’adulte et leur accompagnement en pratique","authors":"Judith Aron-Wisnewsky , Sopio Tatulashvili , Bérénice Segrestin , Cécile Bétry , Najate Achamrah , Blandine Gatta-Chérifi , Fabien Stenard , Jean Marc Catheline , Audren Dumotier , Sébastien Czernichow , Cécile Ciangura , Emmanuel Disse","doi":"10.1016/j.mmm.2025.10.003","DOIUrl":"10.1016/j.mmm.2025.10.003","url":null,"abstract":"","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 8","pages":"Pages 597-628"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145690396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L’examen clinique augmenté : voir et entendre autrement","authors":"Pierre-Yves Benhamou","doi":"10.1016/j.mmm.2025.09.011","DOIUrl":"10.1016/j.mmm.2025.09.011","url":null,"abstract":"","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 503-504"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quand l’intelligence artificielle fragilise les compétences médicales…","authors":"Michael Joubert","doi":"10.1016/j.mmm.2025.08.005","DOIUrl":"10.1016/j.mmm.2025.08.005","url":null,"abstract":"","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 566-567"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le diabète de type 1 est-il encore un diabète maigre ? L’excès pondéral un problème croissant et le risque de plus de complications","authors":"Serge Halimi","doi":"10.1016/j.mmm.2025.09.012","DOIUrl":"10.1016/j.mmm.2025.09.012","url":null,"abstract":"","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 505-508"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parodontopathie : une complication orpheline mais aggravante du diabète – enjeux cliniques, économiques et opportunités de dépistage","authors":"Sophie Schuldiner ,&nbsp;Bruce Plaut ,&nbsp;Affif Zaccaria","doi":"10.1016/j.mmm.2025.09.008","DOIUrl":"10.1016/j.mmm.2025.09.008","url":null,"abstract":"<div><div>La parodontopathie, souvent qualifiée de « sixième complication du diabète », demeure largement sous-diagnostiquée malgré sa prévalence accrue chez les patients diabétiques et son impact délétère sur l’équilibre glycémique et le risque de complications micro- et macrovasculaires. L’inflammation chronique induite par la parodontite contribue à la résistance à l’insuline et augmente la morbidité ainsi que la mortalité toutes causes confondues. À l’inverse, les données scientifiques montrent que le traitement parodontal non chirurgical améliore le contrôle glycémique et réduit les marqueurs inflammatoires systémiques. Pourtant, l’accès aux soins parodontaux reste limité dans la population diabétique, créant un angle mort de santé publique aux conséquences cliniques et économiques importantes. Cet article synthétise les données épidémiologiques et physiopathologiques disponibles, met en évidence les bénéfices médico-économiques du traitement parodontal et souligne le rôle clé du diabétologue dans le dépistage. Enfin, il explore de nouvelles approches, telles que la télé-expertise et l’intelligence artificielle, comme leviers pour intégrer l’évaluation parodontale au parcours de soins des patients diabétiques.</div></div><div><div>Periodontal disease, often referred to as the “sixth complication of diabetes”, remains underdiagnosed despite its high prevalence among people with diabetes and its detrimental impact on glycemic control and the risk of both micro- and macrovascular complications. Chronic inflammation associated with periodontitis contributes to insulin resistance, increased morbidity, and higher all-cause mortality. Conversely, robust evidence demonstrates that non-surgical periodontal treatment improves glycemic control and reduces systemic inflammatory markers. However, access to periodontal care remains limited in the diabetic population, representing a public health blind spot with significant clinical and economic consequences. This article reviews current epidemiological and pathophysiological evidence, highlights the clinical and economic benefits of periodontal treatment, and emphasizes the central role of diabetologists in screening. Finally, it discusses innovative approaches, including tele-expertise and artificial intelligence, as promising tools to integrate periodontal assessment into diabetes care pathways.</div></div>","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 531-539"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La main diabétique","authors":"L. Gillard","doi":"10.1016/j.mmm.2025.09.006","DOIUrl":"10.1016/j.mmm.2025.09.006","url":null,"abstract":"<div><div>La main diabétique représente une complication musculosquelettique fréquente chez les patients atteints de diabète, bien que moins reconnue que le pied diabétique. L’hyperglycémie chronique due au diabète est responsable de la glycation du collagène, ce qui entraîne une perte importante de la mobilité des articulations, des capsules tendineuses et des tendons. La main diabétique regroupe un ensemble d’affections classées sous le terme de <em>Limited Joint Mobility Syndrome</em> (syndrome d’enraidissement articulaire). Les conséquences fonctionnelles peuvent être majeures, avec un retentissement variable sur l’autonomie et la qualité de vie des patients.</div></div><div><div>The diabetic hand syndrome represents a frequent musculoskeletal complication in patients with diabetes, although it is less well recognized than the diabetic foot. Chronic hyperglycemia is responsible for the glycation of collagen, leading to a significant loss of mobility in joints, tendon sheaths, and tendons. The diabetic hand encompasses a set of conditions classified under the term Limited Joint Mobility Syndrome. Functional consequences can be severe, with a variable impact on patients’ autonomy and quality of life.</div></div>","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 540-548"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pourquoi un dossier sur les complications orphelines du diabète ?","authors":"Pierre Yves Benhamou","doi":"10.1016/j.mmm.2025.09.007","DOIUrl":"10.1016/j.mmm.2025.09.007","url":null,"abstract":"","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 510-511"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabète et pathologies audio-vestibulaires","authors":"Raphaële Quatre ,&nbsp;Sébastien Schmerber ,&nbsp;Ashley Baguant","doi":"10.1016/j.mmm.2025.06.001","DOIUrl":"10.1016/j.mmm.2025.06.001","url":null,"abstract":"<div><div>Le lien de causalité entre le diabète et une atteinte du système audio-vestibulaire demeure encore incertain à ce jour. Toutefois, plusieurs études ont révélé une incidence deux fois plus élevée de surdités neurosensorielles chez les patients diabétiques, ainsi qu’une altération accrue des organes otolithiques et des canaux semi-circulaires, augmentant ainsi le risque de chutes chez ces patients, notamment en cas de rétinopathie ou neuropathie diabétique. La durée d’évolution du diabète, sa gravité et l’âge des patients apparaissent comme des facteurs de risque indépendants influençant l’atteinte de l’oreille interne. Des études sur les os temporaux et des modèles animaux ont également confirmé les lésions spécifiques de l’oreille interne associées à cette pathologie. Il est donc crucial de procéder à un dépistage des troubles auditifs et du risque de chute chez ces patients, surtout compte tenu de la durée prolongée et de la gravité du diabète.</div></div><div><div>The causal link between diabetes and damage to the audiovestibular system remains uncertain to this day. However, several studies have shown a twofold higher incidence of sensorineural hearing loss in diabetic patients, as well as increased damage to the otolithic organs and semicircular canals, thereby raising the risk of falls, particularly in patients with diabetic retinopathy or neuropathy. The duration of diabetes, its severity, and the age of the patients appear to be independent risk factors influencing inner ear damage. Studies on temporal bones and animal models have also confirmed specific inner ear damage related to this condition. Therefore, screening for auditory disorders and fall risk in these patients is essential, especially given the long duration and severity of diabetes.</div></div>","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 512-517"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surpoids et obésité : impact sur la fertilité et la grossesse des femmes à Tébessa, Algérie","authors":"Khalida Abla ,&nbsp;Nassima Toumi-Halaimia ,&nbsp;Sawssane Ziani ,&nbsp;Ines Benamer ,&nbsp;Asma Kraidia","doi":"10.1016/j.mmm.2025.02.003","DOIUrl":"10.1016/j.mmm.2025.02.003","url":null,"abstract":"<div><div>Le surpoids et l’obésité ont vu leur prévalence augmenter dans la population féminine en âge de procréer et sont de plus en plus fréquents lors des consultations pour infertilité. L’objectif de notre travail a été d’étudier l’impact de l’obésité sur la grossesse et la fertilité des femmes en surcharge pondérale vs une population à IMC normal. Ont été recrutées 180 femmes adultes, mariées, dont 90 normopondérales et 90 en surcharge pondérale, choisies de façon aléatoire. Ces femmes sont âgées de 20 à 49 ans (34,5<!--> <!-->±<!--> <!-->6,5 ans), pas de différence significative entre obèses et témoins. La majorité des femmes obèses présente une répartition androïde de la masse grasse. Sur le plan gynécologique, l’obésité est significativement associée aux spanioménorrhées, l’oligoménorrhée, l’anovulation, et l’altération de la qualité ovocytaire. Une corrélation positive a été retrouvée entre l’IMC et le délai normal à concevoir (DNC) des femmes obèses. La prévalence de l’infertilité retrouvée dans notre étude est de 31,1 %. Elle est significativement plus fréquente chez les femmes obèses (38,9 %) comparé aux témoins (23,3 %). Au cours des grossesses, l’obésité est significativement associée à des complications gestationnelles notamment l’HTA et l’accouchement par césarienne. Enfin, la relation obésité/infertilité, retrouvée dans notre étude, semble principalement être due aux troubles du cycle liés à la surcharge pondérale, qui semblent être le mécanisme prédominant impactant sur la fécondabilité des femmes.</div></div><div><div>Overweight and obesity have seen their prevalence increase in the female population of childbearing age and are increasingly frequent during consultations for infertility. The objective of our work was to study the impact of obesity on pregnancy and fertility in overweight women vs. a population with a normal BMI. We recruited 180 adult married women, including 90 normal weight and 90 overweight, chosen randomly. These women are aged 20 to 49<!--> <!-->years (34.5<!--> <!-->±<!--> <!-->6.5<!--> <!-->years), no significant difference between obese and controls. The majority of obese women have an android distribution of fat mass. On the gynecological level, obesity is significantly associated with spaniomenorrhea, oligomenorrhea, anovulation, and alteration of oocyte quality. A positive correlation was found between BMI and normal time to conceive (NTC) of obese women. The prevalence of infertility found in our study is 31.1%. It is significantly more frequent in obese women (38.9%) compared to controls (23.3%). During pregnancy, obesity is significantly associated with gestational complications including hypertension and cesarean delivery. Finally, the obesity/infertility relationship found in our study seems to be mainly due to cycle disorders related to excess weight, which seem to be the predominant mechanism impacting on the fecundability of women.</div></div>","PeriodicalId":35047,"journal":{"name":"Medecine des Maladies Metaboliques","volume":"19 7","pages":"Pages 568-573"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}