Chenyu Jiang, J. Cui, Yanbo Shi, Ning-ning Dong, Fan Wang, Huiming Tan
{"title":"LIBS: A new method for heavy metal in biomedical field and applied in plasma medical","authors":"Chenyu Jiang, J. Cui, Yanbo Shi, Ning-ning Dong, Fan Wang, Huiming Tan","doi":"10.1109/ISBB.2011.6107683","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107683","url":null,"abstract":"Laser induced breakdown spectroscopy (LIBS) is characterized by non-contract and real-time analysis, which can meet the need of high-speed and automatic in industry and agriculture production and biomedical field. In this paper, the lead concentrations of samples included in glass, pig blood and so on are determinate by LIBS, based on a Nd: YAG Q-switched pulse with wavelength 1064 nm as an exciting source and nongated CCD in common spectrograph as detector. The energy of pulse on the surface of samples is about 100mJ and the width of pulse is 12ns. By the detection of different samples, we definite the detection limit of lead in samples is found to be 0.0074% and the LOD in theory is 0.0074% based on the LIBS system of the instruments all made in China. We found that the difference between the common pig blood and the organic pig blood is the content of K. The results suggest that the accuracy of determination of lead meets the challenge of quantitative analysis and the CCD can displace the ICCD which is very expensive as detector. The feasibility and low cost of the method which uses common spectrometer and CCD to realize the LIBS detection is proved by the result and our investigation will be beneficial to the LIBS application in biomedical field and food safety.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133293801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shujuan Geng, Weidong Zhou, Qi Yuan, Zheneng-hua Ma
{"title":"Bifurcation phenomenon of wendling's EEG model","authors":"Shujuan Geng, Weidong Zhou, Qi Yuan, Zheneng-hua Ma","doi":"10.1109/ISBB.2011.6107658","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107658","url":null,"abstract":"In this paper, we present a mathematical analysis of an EEG model proposed by Wendling et al. We analyze the Hopf bifurcation and saddle-node bifurcation phenomenon of the model for explaining how it can produce several different types of EEG activity. We give a fairly detailed description of the behavior of the model by the bifurcation diagram. Study on bifurcations of Wendling's model provides further theoretical reference for understanding brain's nonlinear electric activity.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129543710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Small-world properties of human brain functional networks based on resting-state functional MRI","authors":"Wentao Huang, Youceng Feng","doi":"10.1109/ISBB.2011.6107657","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107657","url":null,"abstract":"Studying the resting state functional activities of healthy human brain will aid us to understand the patterns of functional activities of human brain in normal or disease states. Time series of 90 brain regions were extracted from resting state functional magnetic resonance imagines in 19 healthy volunteers. Functional correlations between brain regions were calculated, and the thresholds were set to establish the simple undirected graphs, then some measurements of brain functional networks were computed, finally the degree distribution was fitted. The results confirmed that the human brain functional networks have both big clustering coefficients like regular networks and small characteristic path lengths similar like random networks, degree distribution met exponentially truncated power-law distribution. Taken together, the brain functional networks have small world properties.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133789275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tengfei Leng, Ze-dong Nie, Wenchen Wang, Feng Guan, Lei Wang
{"title":"A human body communication transceiver based on on-off keying modulation","authors":"Tengfei Leng, Ze-dong Nie, Wenchen Wang, Feng Guan, Lei Wang","doi":"10.1109/ISBB.2011.6107645","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107645","url":null,"abstract":"This paper presents an on-off keying (OOK) human body communication (HBC) transceiver design method for wireless body-area network (WBAN). The HBC channel in shield chamber by adopting floating ground experiment setup is analyzed and the optimal carrier frequency of 30 MHz is chosen. A FPGA and a direct-digital synthesizer (DDS) are applied to achieve OOK modulation in the HBC transmitter. In the receiver part, the signal is firstly filtered by a band pass filter, and then converted to voltage through a logarithmic amplifier. Finally a comparator and a clock data recover (CDR) circuit are used to recovery the data. The proposed HBC transceiver is implemented in a PCB board and validated in human body. The result shows that the transceiver can transfer 2-Mbps none return zero (NRZ) data from forearm to finger through the human body successfully.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126676721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Ruixue, L. Dayu, Xiang Mingliang, Kong Ningning, Qi Yue, Zheng Xian-liang, Xuan Li
{"title":"Laser beacon adaptive optics ophthalmoscope for retinal multilayer imaging","authors":"Li Ruixue, L. Dayu, Xiang Mingliang, Kong Ningning, Qi Yue, Zheng Xian-liang, Xuan Li","doi":"10.1109/ISBB.2011.6107664","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107664","url":null,"abstract":"A flood-illuminated adaptive optics ophthalmoscope for retinal multilayer imaging is introduced in this paper. By arranging an alterable stop in the illumination path, the illuminated area of retinal layer can be changed. A laser beacon for wavefront sensing is formed when the stop is a narrow aperture. The large aperture allows flood illumination and expands imaging field. A moveable imaging camera can focus on different layers of the retina. In the confirming experiment, a subject who was a 25-years-old normal health Chinese male was imaged. We got clear images of photoreceptor layer, blood vessels and nerve fiber layer.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129533389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tan Jian-wen, Liao Rui-jin, Wang Hua, Li Long, Qiang Sheng-ze
{"title":"Time domain electrical impedance measurement method for ultrasound transducer","authors":"Tan Jian-wen, Liao Rui-jin, Wang Hua, Li Long, Qiang Sheng-ze","doi":"10.1109/ISBB.2011.6107701","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107701","url":null,"abstract":"High intensity focused ultrasound transducer (HIFU) is a key part of HIFU treatment system, the electrical impedance characteristics of which is an important parameter. The currently adopted electrical impedance measurement methods are based on frequency-domain, which are expensive and difficult to realize on-line measurement. The time-domain measurement method for electrical impedance of high intensity focused ultrasound transducer based on impulse response is studied in this paper. The principle of measurement is theoretically analyzed and verified through simulation. The measurement platform is experimentally established and the measurement results of impedance analyzer and impulse response method are compared. The approaches of current sampling resistor correction and wavelet denoising to reducing measurement error are presented. The study results show that: the impulse response measurement method can obtain good measurement accuracy after current sample resistance correcting and wavelet denoising; the measurement method is cost-effective and convenient for integrating in equipment to realize on-line measurement. This measurement method also provides an effective means of researching electrical impedance characteristic of high intensity focused ultrasound transducer.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128672361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automated detection of plantar pressure ROIs based on multiple frame data","authors":"Z. Mei, G. Zhao, L. Wang","doi":"10.1109/ISBB.2011.6107638","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107638","url":null,"abstract":"Semi-automatic or manual method were usually used to define the region of interest (ROI) of dynamic plantar pressure for foot's biomechanical research. However, the existing methods are time-consuming, complicated, or unrepeatable. So, automatic method to extract ROIs is needed. Moreover, spatial adjacency of ROIs in the forefoot put forward the challenge for automatic methods. The objective of this study is to find out an automatic method for defining the ROIs using dynamic plantar pressure information of multiple frames. Twenty subjects were asked to participate in tests. The plantar pressure data and 3D kinematical data were collected. The maximal inter-frame difference during stand phase was calculated. Then the locations of ROIs were determined by using maximal inter-frame difference and priori knowledge about spatial relation of anatomical location of ROIs. Recognition accuracy by using our method was compared with by using Motion Analysis. The results indicated that using inter-frame difference was able to produce recognition accuracy 100%, 100%, 90%, 100%, 90%, 90% for halluces and metatarsus I to V, respectively, which had highly agreement with the result of 3D motion capture system. Furthermore, our method is simple and discreet, which could be employed in wider applications.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124743629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jia-Hua Hong, Ming-Chun Liang, Ming-Yang Haung, T. Tsai, Q. Fang, Shuenn-Yuh Lee
{"title":"Analog front-end circuit with low-noise amplifier and high-pass sigma-delta modulator for an EEG or ECoG acquisition system","authors":"Jia-Hua Hong, Ming-Chun Liang, Ming-Yang Haung, T. Tsai, Q. Fang, Shuenn-Yuh Lee","doi":"10.1109/ISBB.2011.6107634","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107634","url":null,"abstract":"The present paper proposes an analog front-end (AFE) circuit, including only one low-noise amplifier with chopping techniques and one high-pass sigma-delta modulator (HPSDM), which can be applied as a sensing circuit for electroencephalogram or electrocorticogram (ECoG) signal acquisition systems. The low-noise amplifier, which has a close-loop gain of 20 V/V and CMRR of 109.6 dB, is implemented by a differential difference amplifier with feedback pseudo-resistors and capacitors. The HPSDM is implemented in a feed-forward architecture with an order of 3, an oversampling ratio of 128, and a 1-bit quantizer under a sampling frequency of 51.2 kHz. The TSMC 0.18 μm 1P6M CMOS process is used in the entire AFE circuit with a supply voltage of 1.2 V and power consumption of 28.7 μW. Within the maximum range of ECoG signals, the simulated SNR and SFDR of the entire AFE circuits are 70.8 and 73 dB, respectively.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134296181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automated detection and quantification of early caries lesions on images captured by intraoral camera","authors":"Jiayong Yan, Yongjia Xiang, X. Jian","doi":"10.1109/ISBB.2011.6107694","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107694","url":null,"abstract":"In recent years, quantifying the severity of early caries lesions based on white light and/or fluorescence images captured by intraoral camera has been becoming a hot spot in caries research field. In order to quantify the severity of the early caries lesions, it needs to detect and segment the caries lesions accurately first. However, to date, the published methods are mainly based on threshold techniques, and it is difficult to obtain desirable results because the intensity of the teeth changes significantly. To solve this problem, this paper presents an automated detection and quantification algorithm by using a morphological top-hat/bottom-hat method along with a multi-resolution surface reconstruction technique, which is based on local intensity and morphological characteristics of caries images captured by the intraoral oral camera, for early caries lesions. The preliminary experimental results on ex vivo data demonstrated the potential of the proposed algorithm.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122841343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei-zhong Wang, Yanwei Guo, Bang-yu Huang, Guo-ru Zhao, Bo Liu, Lei Wang
{"title":"Analysis of filtering methods for 3D acceleration signals in body sensor network","authors":"Wei-zhong Wang, Yanwei Guo, Bang-yu Huang, Guo-ru Zhao, Bo Liu, Lei Wang","doi":"10.1109/ISBB.2011.6107697","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107697","url":null,"abstract":"Development of denoising algorithm for 3D acceleration signals is essential to facilitate accurate assessment of human movement in body sensor networks (BSN). In this study, firstly 3D acceleration signals were captured by self-developed nine-axis wireless BSN platform during 12 subjects performing regular walking. Then, acceleration noise was filtered using four common filters respectively: median filter, Butterworth low-pass filter, discrete wavelet package shrinkage and Kalman filter. Finally, signal-to-noise ratio (SNR) and correlation coefficient(R) between filtered signal and reference signal were determined. We found that (1) Kalman filter showed the largest SNR and R values, followed by median filter, discrete wavelet package shrinkage and finally Butterworth low-pass filter; whereas, after correcting waveform delay for Butterworth low-pass filter, its performance was a little better than that of Kalman filter; (2) Real-time performance of median filter related to its window length; Decomposition level influenced real-time performance of discrete wavelet package shrinkage; Butterworth low-pass filter could bring large waveform delay if filter order and cut-off frequency were not properly selected. The algorithms of these filters would be further investigated to achieve best noise reduction of 3D acceleration signals in future.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115853524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}