International Symposium on Bioelectronics and Bioinformations 2011最新文献_第5页

Optimized inverse recovery pulse sequence improves contrast in magnetic resonance 优化的逆恢复脉冲序列提高了磁共振成像的对比度

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107684

Xiaodong Yang, Xiaoxia Du, Zhenwei Zhu, Yajie Xu, Haoran Tian, Daxiu Wei

引用次数: 0

Development of planar microelectrode array for extracellular characterization of action potentials in sinoatrial node cells 用于窦房结细胞外动作电位表征的平面微电极阵列的研制

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107630

Xin Zhang, Yulong Zhang, Yingxin Li, R. D. Nelson, J. LaRue

{"title":"Development of planar microelectrode array for extracellular characterization of action potentials in sinoatrial node cells","authors":"Xin Zhang, Yulong Zhang, Yingxin Li, R. D. Nelson, J. LaRue","doi":"10.1109/ISBB.2011.6107630","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107630","url":null,"abstract":"In this research work we prototyped a planar microelectrode arrays that utilize SU-8 as the insulating material for non-invasive chronically characterization of action potentials from SA node cells. The microelectrode arrays are fabricated to form a microchannel based extracellular action potential characterization system which comprises a 2 by 50 linear microelectrode array for acquiring the action potentials with the principle of capacitive coupling and a full customized CMOS analog bio-signal readout ASIC for bio-signal conditioning and processing. The prototyped multi-channel mixed signal fully-customized CMOS biosensor analog front-end serves as the low magnitude action potential signal readout circuitry, which is comprised of analog signal buffers, high gain amplifier and control/interface. The concept of using epoxy-based photoresist SU-8 as the insulator instead of the conventional silicon nitride or silicon dioxide is due to the high insulation property and bio-compatibility of the SU-8 material. This biocompatible planar microelectrode arrays with microchannels provides the biological scientists powerful tools for the long term non-invasive study of action potentials from SA node cells to screen libraries of chemical compounds for new drug candidates.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116196645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Low-power systematic integration of the instrumentation amplifier and the OTA-C filter for ECG acquisition systems 用于心电采集系统的仪表放大器和OTA-C滤波器的低功耗系统集成

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107643

T. Tsai, Yen-Cheng Chen

引用次数: 3

Monitoring dynamic characteristics of treated region during high intensity focused ultrasound (HIFU) treatment 高强度聚焦超声(HIFU)治疗过程中治疗区域动态特性监测

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107652

Hui Zhong, M. Wan, Siyuan Zhang

引用次数: 0

X-corner detection based on segment test applied in optical pose tracking system 基于片段测试的x角检测在光学姿态跟踪系统中的应用

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107671

Hao Xu, Bo Sun

引用次数: 4

Template matching based motion classification for unsupervised post-stroke rehabilitation 基于模板匹配的无监督脑卒中后康复运动分类

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107680

Zhe Zhang, Qiang Fang, Liuping Wang, Peter Barrett

{"title":"Template matching based motion classification for unsupervised post-stroke rehabilitation","authors":"Zhe Zhang, Qiang Fang, Liuping Wang, Peter Barrett","doi":"10.1109/ISBB.2011.6107680","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107680","url":null,"abstract":"Post-stroke rehabilitation training is proven clinically to be essential and effective on helping stroke patients to regain part of the functionality of their body. In recent years, cost-efficient rehabilitation training programs especially unsupervised training have become a popular research area due the increasing number of post-stroke hospitalizations and the high healthcare expenditure associated. In order to achieve unsupervised rehabilitation training, a reliable continuous monitoring measure is crucial. This paper proposed a motion classification system based on template matching technique that can constantly identify and record the quantity and quality of patient's rehabilitation exercise as a reference for the professionals to analyze patient's recovery progress. It can also integrate features like fall detection to improve safety in unsupervised training environment. In contrast to the conventional motion tracking system which are generally expensive and complicated to operate, the proposed system uses only low-cost non-visual based wireless sensors for acceleration data collection. Since the classification process is based on template matching, there are no additional sensors like gyroscope required for precise reconstruction of patient's motion. To test the system performance, a preliminary experiment involving an actual stroke patient has been conducted. Despite the movement performed by the patient was non-standard and inconsistent, the system was still able to identify the predefined exercises from a series of movements and count the number of repetition for each exercise accurately.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127944663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Freehand 3D ultrasound reconstruction for image-guided surgery 用于图像引导手术的徒手三维超声重建

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107667

Tao Qiu, Tiexiang Wen, Wenjian Qin, Jia Gu, Lei Wang

{"title":"Freehand 3D ultrasound reconstruction for image-guided surgery","authors":"Tao Qiu, Tiexiang Wen, Wenjian Qin, Jia Gu, Lei Wang","doi":"10.1109/ISBB.2011.6107667","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107667","url":null,"abstract":"Three-dimensional (3D) ultrasound (US) is increasingly being introduced in the clinic, both for diagnostics and image guidance. Obtaining 3D volumes with 2D US probes is a two-step process. First, a positioning sensor must be attached to the probe; second, a reconstruction of a 3D volume can be performed into a regular voxel grid. Various algorithms have been used for performing 3D reconstruction based on 2D images. In this paper, we propose a new Hole-filling algorithm using Distance Weight interpolation, and we also apply it to generate the volume in our Image-guided for surgical robot. First, the ultrasound frames and position information are compounded into a 3D volume using the Bin-filling method. Then, the Hole-filling method is used to repair gaps in the volume. We define the empty voxels by sorting the neighboring voxels into three parts, and averaging them to obtain the value to fill the empty voxels according to distance weighted. The empty voxel estimation can be improved by thresholding the range width of its neighboring voxels and adjusting it to the average values. The method is tested on a Hole-manipulated volume derived from a cropped 3D ultrasound volume of chicken kidney. Our method shows improved result compared to several tested existing methods, including voxel nearest neighbour(VNN) and spline function interpolation.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116809623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Small-world properties of human brain functional networks based on resting-state functional MRI 基于静息状态功能MRI的人脑功能网络小世界特性研究

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107657

Wentao Huang, Youceng Feng

引用次数: 1

LIBS: A new method for heavy metal in biomedical field and applied in plasma medical LIBS:生物医学领域重金属检测新方法，在血浆医学中的应用

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107683

Chenyu Jiang, J. Cui, Yanbo Shi, Ning-ning Dong, Fan Wang, Huiming Tan

{"title":"LIBS: A new method for heavy metal in biomedical field and applied in plasma medical","authors":"Chenyu Jiang, J. Cui, Yanbo Shi, Ning-ning Dong, Fan Wang, Huiming Tan","doi":"10.1109/ISBB.2011.6107683","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107683","url":null,"abstract":"Laser induced breakdown spectroscopy (LIBS) is characterized by non-contract and real-time analysis, which can meet the need of high-speed and automatic in industry and agriculture production and biomedical field. In this paper, the lead concentrations of samples included in glass, pig blood and so on are determinate by LIBS, based on a Nd: YAG Q-switched pulse with wavelength 1064 nm as an exciting source and nongated CCD in common spectrograph as detector. The energy of pulse on the surface of samples is about 100mJ and the width of pulse is 12ns. By the detection of different samples, we definite the detection limit of lead in samples is found to be 0.0074% and the LOD in theory is 0.0074% based on the LIBS system of the instruments all made in China. We found that the difference between the common pig blood and the organic pig blood is the content of K. The results suggest that the accuracy of determination of lead meets the challenge of quantitative analysis and the CCD can displace the ICCD which is very expensive as detector. The feasibility and low cost of the method which uses common spectrometer and CCD to realize the LIBS detection is proved by the result and our investigation will be beneficial to the LIBS application in biomedical field and food safety.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133293801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression analysis of Mirna Isomirs from deep sequencing data 基于深度测序数据的Mirna Isomirs表达分析

International Symposium on Bioelectronics and Bioinformations 2011 Pub Date : 2011-12-19 DOI: 10.1109/ISBB.2011.6107686

Qi Yang, Jiafeng Lu, Shengqin Wang, Qinyu Ge, Zuhong Lu

{"title":"Expression analysis of Mirna Isomirs from deep sequencing data","authors":"Qi Yang, Jiafeng Lu, Shengqin Wang, Qinyu Ge, Zuhong Lu","doi":"10.1109/ISBB.2011.6107686","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107686","url":null,"abstract":"Recently, several researches have reported the novel phenomena of microRNA isoforms (isomiRs), that microRNAs (miRNAs) can exhibit heterogeneous ends in 5' and 3' end, both addition and subtractionof diverse oligonucleotide. With the benefit of high-throughput sequencing technology, the expression profiles of miRNAs were analyzed here in the samples of the placentas of pregnant women after their delivery. By analyzing the profiles of miRNAs in four samples, we found three notable results. (1) The phenomenas of isomiRs were ubiquitous in all four samples. (2) The heterogeneous ends in 3'end were more significantly than in 5' end, but showed no novel difference between the addition and subtraction of nucleotide in the ends. (3) The isomiRs with one and two nucleic acids heterogeneous took up approximately the same percentage with the mature miRNA in miRBase, and those isomiRs with more than 2 nt differences only took small part of the total miRNAs in the profiles. These results indicated the isomiRs maybe not just the inexact Dicer processing, but were the product of pre-miRNAs with some unknown but special bio-rules, which could give some impressing suspects for researches to better understand this novel phenomena ofisomiRs.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133549836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0