{"title":"Realization of a monitoring system of respiratory mechanics parameters based on sensors","authors":"Zhiwei Huang, D. Yin, Gaofei Cao, Bo Xiao","doi":"10.1109/ISBB.2011.6107682","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107682","url":null,"abstract":"We design a monitoring system of respiratory mechanical parameters based on flow and pressure sensors, discuss the key issues such as sensor selection, amplification circuit, three-way valve control circuit, and describe system's application procedures and the function that man-machine interface achieved. Then we compare and verify that the system can accurately monitor parameters in the laboratory and effectively meet the application needs of monitoring respiratory mechanical parameters in the clinical.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132535487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multi-region level set image segmentation based on image cartoon-texture decomposition model","authors":"XueMin Yin, Jianping Guo, Chong-Fa Zhong, Yukao Yao, Zhe Zhang, Yi Wei","doi":"10.1109/ISBB.2011.6107653","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107653","url":null,"abstract":"This paper presents a multi-region level set image segmentation method based on image cartoon - texture decomposition model. The image feature is extracted by using the image decomposition method. We represent the regions by the level set functions with constraint. The coupled Partial Differential Equations (PDE) related to the minimization of the functional are considered through a dynamical scheme. A modified region competition factor is introduced to guarantee no vacuum and non-overlapping between the neighbor regions, it also speed up the cure evolution functions, the final segmentation can be achieved after several iterations. Several experiments are conducted on both synthetic images and natural images, the results illustrate that the proposed multi-region segmentation method is fast and less sensitive to the initializations.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134375907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical simulation of T mixer for the study of protein folding","authors":"Hua Lu, Dacan Yang","doi":"10.1109/ISBB.2011.6107676","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107676","url":null,"abstract":"T mixers are widely used in protein folding experiments. In this paper, numerical simulation method was used to characterize the mixing performances of two T mixers. The results showed that these mixers could achieve efficient solution mixing from tens of microseconds to several hundreds of microseconds. It is concluded that numerical simulation will aid further optimization of mixer design.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122267078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Campbell, I. Campbell, P. Axford, Yaoyao Cui, Peter K. J. Robertson
{"title":"Application of ultrasound for sonodynamic photocatalysis","authors":"P. Campbell, I. Campbell, P. Axford, Yaoyao Cui, Peter K. J. Robertson","doi":"10.1109/ISBB.2011.6107650","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107650","url":null,"abstract":"Ultrasound has long been recognized as a means of effecting change at the cellular and tissue levels [1–3], which may be enhanced in the presence of photosensitive agents [4–6]. During insonation, the presence of bubbles can also play a role, creating strong microstreaming effects in solution and in more dramatic circumstances leading to the formation of energetic microjets [7], plasmas [8], and the production of other highly reactive species [9]. Such ‘sonodynamic activity’ has generated particular excitement in the medical community as it Moreover the dual role for microbubbles as both an adjunct to therapy and a diagnostic echogenicity enhancer has seen industry take a proactive role in their development. In the present paper we studied the role of ultrasound driven sonoluminescent light on the degradation of a fluorescent test species (rhodamine) in the presence of an archetypal photocatalyst material, TiO2, with a view to exploring its exploitation potential for downstream medical applications. We found that, whilst the efficiency of this process is seen to be low compared with conventional ultra-violet sources, we advocate the further exploration of the sonoluminescent approach given its potential for non-invasive applications. A strategy for enhancing the effect is also suggested.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130167737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng-Han Hsieh, Mario YuCheng Su, J. Kung, Shuenn-Yuh Lee, Q. Fang
{"title":"Low-power 13.56 MHz RF front-end circuit for body sensor network","authors":"Cheng-Han Hsieh, Mario YuCheng Su, J. Kung, Shuenn-Yuh Lee, Q. Fang","doi":"10.1109/ISBB.2011.6107635","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107635","url":null,"abstract":"The current paper presents a fully integrated CMOS RF front-end circuit with low-power consumption for passive 13.56 MHz biomedical implants. The 13.56 MHz carrier frequency of the binary phase shift keying (BPSK) signal is transmitted to the body through the external and internal coils. The full-wave bridge rectifier of biomedical implants rectifies the BPSK signal received from the internal coil, and it is converted into DC power supply by the linear regulator to generate a stable DC output of 1.8 V. The fully digital BPSK demodulator demodulates the received BPSK signal for the clock/data separator to recover clock and data, which are required by the back-end circuit. This chip is designed and fabricated in TSMC 0.18 μm 1P6M CMOS technology, with an area of 1.35 mm2 and power consumption of 632 μW.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127931158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Feng Guan, Ze-dong Nie, Wenchen Wang, Tengfei Leng, Lei Wang
{"title":"A low noise amplifier for human body communication RF front-end design","authors":"Feng Guan, Ze-dong Nie, Wenchen Wang, Tengfei Leng, Lei Wang","doi":"10.1109/ISBB.2011.6107695","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107695","url":null,"abstract":"A Low Noise Amplifier (LNA) for Human Body Communication (HBC) RF front-end was presented in this paper. The circuit was designed with SMIC 0.18um process and simulated with Cadence Spectre. HBC characteristics, such as channel pass band and attenuation were investigated prior to the design. An active noise cancellation technique was employed to achieve low noise figure. And resistor feedback technique was introduced to meet the design specifications. Post-annotated simulations showed that the LNA with an active area of 60μm×50μm worked as intended. Within the frequency band from 100 KHz to 100MHz, the minimum noise figure was 1.82 dB and the S21 value was 19.5 dB, respectively.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"96 13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127990789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bin Liu, Lingling Guo, Yan Deng, Bobo Zhang, N. He
{"title":"Research of temperature control algorithm in PCR gene amplify instrument","authors":"Bin Liu, Lingling Guo, Yan Deng, Bobo Zhang, N. He","doi":"10.1109/ISBB.2011.6107660","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107660","url":null,"abstract":"To achieve stable and accurate temperature control in PCR gene amplify instrument, A complex PID control algorithm, including Bang-Bang control and Fuzzy-PID control algorithm, was proposed in this paper to improve the control dynamical and stable ability. The hardware of PCR gene amplify instrument and PID controller and fuzzy logic reasoning are introduced in this paper. The process of PID controller, fuzzy logic PID controller and fuzzy logic velocity PID controller controls nonlinearity system are emulated respectively with MATLAB SIMULINK, so that the control result can be compared. Experiments in the self-made PCR gene amplify instrument manifest fuzzy logic velocity PID is the most stable and accurate temperature control algorithm.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122781487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantification of collagen alteration in mid-dermis of skin lesion with mucinosis using second harmonic generation imaging","authors":"Lihang Lin, Xiaoqin Zhu, Haibo Yu, Jianxin Chen","doi":"10.1109/ISBB.2011.6107670","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107670","url":null,"abstract":"Cutaneous mucinoses are a heterogeneous group of diseases characterized by abnormal deposition of dermal mucin. Considering the collagen disorder due to the mucin deposition, collagen microstructure was visualized by second harmonic generation (SHG) microscopy to gain structural and diagnostic information. High resolution images of collagen in the dermis of skin lesion with mucinosis and healthy skin showed differences in their microstructures. SHG density as well as depth dependant decay coefficient was analyzed to quantitatively characterize the microstructure. Our results demonstrated the possibility of SHG imaging to in vivo tracking the pathological process of mucinoses and evaluate the therapeutic efficacy.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114171797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design of motor function restoration system based on myoelectric signals recognition","authors":"Zonghao Huang, Zhigong Wang, Xiaoying Lv, Yuxuan Zhou, Xintai Zhao, Jingdong Yang","doi":"10.1109/ISBB.2011.6107665","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107665","url":null,"abstract":"In this paper, a system aiming at motor function restoration based on myoelectric signals recognition has been presented. This system contains four main components: analog front, AD converter, digital signal processor, and functional electrical stimulator. Functions and designing consideration of each component, and a myoelectric signals recognition algorithm with low computational complexity have been introduced. Finally, the testing results of the system will be presented and the qualified performance for the further animal experiment is demonstrated.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121831905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perylene diimide-based organic fluorescent nanorods for live cell imaging","authors":"Meng-Meng Song, Hong Bi, Liang Wang, Le Yu","doi":"10.1109/ISBB.2011.6107672","DOIUrl":"https://doi.org/10.1109/ISBB.2011.6107672","url":null,"abstract":"Cell imaging with fluorescent, magnetic or bimodal nanoparticles is currently undergoing a rapid development. The goal of this study was to evaluate the feasibility and efficiency of cell imaging by using a novel kind of organic fluorescent nanorods without any other dye staining or antibody labeling. Perylene-3, 4, 9, 10-tetracarboxdiimide (PDI) nanorods with uniform diameters (ca. 50 nm) and in a length range of 100–600 nm were fabricated by a template-assisted self-assembly method. The PDI nanorods showed a strong fluorescent emission in the visible range and favorable dispersity in aqueous solution. Human hepatoma (HepG2) cells, Hela cells and human embryonic fibroblasts (HEFs) were chosen as models to investigate the cytotoxicity and the cell imaging effect. MTT assays demonstrated the cytotoxicity of PDI nanorods was concentration-dependent and the 72 h IC50 value were in the range of 42–55 μg/mL which is much higher than that of reported quantum dots (QDs). Particularly, con-focal laser scanning microscopy (CLSM) and transmission electron microscopy (TEM) observations indicated PDI nanorods were able to be internalized into the cells very readily and mostly located in the cytoplasm. Moreover, they were found exhibiting a stable, bright fluorescence as long as several hours within the cells. Besides, the uptake of PDI nanorods was found through an energy-dependent, endocytosis-mediated process.","PeriodicalId":345164,"journal":{"name":"International Symposium on Bioelectronics and Bioinformations 2011","volume":"379 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123440098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}