2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)最新文献_第5页

A Self-Organizing Bucket Brigade 一个自我组织的水桶队

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.22

J. Pelesko

引用次数: 5

In Vitro Gene Transfection with Surface-Modified Gelatin Nanoparticles 表面修饰明胶纳米颗粒的体外基因转染

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.81

Klaus Zwiorek, Julia Kloeckner, E. Wagner, C. Coester

{"title":"In Vitro Gene Transfection with Surface-Modified Gelatin Nanoparticles","authors":"Klaus Zwiorek, Julia Kloeckner, E. Wagner, C. Coester","doi":"10.1109/ICMENS.2004.81","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.81","url":null,"abstract":"With the development of the two step desolvation method for the preparation of gelatin nanoparticles, it is possible to reproducibly generate homogeneous colloidal spheres. After the establishment of a surface modification to achieve stable nucleotide loading onto the particles, the goal of this study was to test this new biodegradable and simple producible non-viral gene delivery system in vitro. Two different types of gelatin nanoparticles, referring to size and zeta (ζ) potential were investigated. Therefore, we varied conditions as for example the loaded DNA amount and the conjugation media to find a preferable setup. All preparations were tested on B16F10 murine melanoma cells using pCMVLuc as reporter gene. To evaluate our results, we used commonly known, but non-biodegradable, polyethylenimine (PEI) polyplexes as \"gold standard\" for in vitro transfection. Additionally, we performed accompanying cell viability assays and hemolysis studies with the preparations tested to substantiate the thesis of low cell toxicity of gelatin nanoparticles. Different setups resulted in efficient gene delivery. The achieved levels of gene expression were good but lower as with optimized PEI polyplexes. Nevertheless, the already achieved results show gelatin nanoparticles as promising biodegradable alternative to existing non-viral gene delivery systems.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132104048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Development of Inhalable Nanoparticles 可吸入纳米颗粒的发展

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.53

Leticia Ely, R. Löbenberg, Zhao-quan Wang, Yu Zhang, W. Finlay, W. Roa, Jeffrey O. H. Sham

引用次数: 3

Advanced MEMS and Integrated-Optic Components for Multifunctional Integrated Optical Micromachines 用于多功能集成光学微机器的先进MEMS和集成光学元件

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.27

R. Kruzelecky, B. Wong, Jing Zou, E. Haddad, W. Jamroz, A. Yelon, R. Beaudry, O. Grenier, Wanping Zheng, L. Phong

{"title":"Advanced MEMS and Integrated-Optic Components for Multifunctional Integrated Optical Micromachines","authors":"R. Kruzelecky, B. Wong, Jing Zou, E. Haddad, W. Jamroz, A. Yelon, R. Beaudry, O. Grenier, Wanping Zheng, L. Phong","doi":"10.1109/ICMENS.2004.27","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.27","url":null,"abstract":"Optical technologies can play a strategic role in improving the performance, functionality, and reducing the mass of various spacecraft technologies, such as true time-delay T/R modules for phased-array antennas and optical sensor systems for satellite navigation and systems status. However, current photonic and fiber-optic systems tend to be bulky relative to the requirements for space applications. Micro integrated-optic circuits increase the integration of optical components on a single substrate, to provide multi-function optical processing and switching similar to electronic integrated circuits. This minimizes the number of external optical interconnections required and sensitivity to external vibrations; maximizing the system information capacity, optical throughput, and reliability, while minimizing the overall system size and weight. This paper considers a systematic development of MEMS integrated-optic circuits on SOI for various space application. A unique blend of MEMS, smart-material and photonic technologies is employed to miniaturize the size of the basic components, while improving on the attainable performance.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114231360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Nanoparticulate Delivery Systems for Control of Immunity 用于免疫控制的纳米颗粒递送系统

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.109

J. Samuel, Praveen Elamanchili, M. Diwan, A. Haddadi, Anahita Dehmoobed

引用次数: 0

Optical Probing of Nanoscopic Insulating Layered Structures via Differential Characteristics of Specular Reflection of Light 基于光的镜面反射特性的纳米绝缘层状结构的光学探测

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.120

P. Adamson

引用次数: 3

The Concept of a 3-D Cubic Acoustical Sensor Microarray Cluster for Use in a Hearing Instrument 用于助听器的三维立方声学传感器微阵列集群的概念

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.140

S. Chowdhury, M. Ahmadi, W. Miller

引用次数: 1

Micro Evaporators 微型蒸发器

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.93

C. Rops, F. V. Graaf, J. Velthuis

{"title":"Micro Evaporators","authors":"C. Rops, F. V. Graaf, J. Velthuis","doi":"10.1109/ICMENS.2004.93","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.93","url":null,"abstract":"The use of micro evaporation for cooling electronic components on small satellites is very promising because of its great potential on heat transferring capacity and its low mass flow. Due to the size reduction, the energy density increases in a lot of applications in space industry. On top of this, the thermal specifications on micro devices are often more tight than in macroscopic applications. Therefore, a proper design is essential for devices to be capable of dealing with associated high heat fluxes. Using evaporation high heat fluxes can be obtained. However, a good understanding of the heat transfer and evaporation on micro scales is necessary since some physical phenomena become more (or less) important. The PhD research performed at TNO TPD (in collaboration with the Delft university of technology) leads to insight on the behaviour of two phase liquid- gas flow in micro channels. The knowledge on both the heat transfer and the two phase flow patterns can be used to formulate relationships which can be used to design micro fluidic systems. Since gravity plays a minor role on micro scales these engineering tools will be appropriate for designing space systems as well.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125191210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Microbolometer Spectrometer: Applications and Technology 微辐射热计光谱仪:应用与技术

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.95

J. Leijtens, A. Court, J. Hoegee

引用次数: 2

From the Pharmacokinetics to the Intracellular Dynamic Phase — Direct Introduction of Nanoparticles into Cytoplasm of Living Cells 从药代动力学到细胞内动力学阶段;纳米颗粒直接导入活细胞细胞质的研究

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.73

T. Mayumi

引用次数: 0