从药代动力学到细胞内动力学阶段;纳米颗粒直接导入活细胞细胞质的研究

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI:10.1109/ICMENS.2004.73

T. Mayumi

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引用次数: 0

摘要

我们开发了一种技术，可以一次直接将纳米颗粒导入活细胞的细胞质中，而无需使用微操纵器。此外，我们证实反义寡核苷酸作为模型药物可以从这些颗粒中缓慢释放到细胞质中。

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From the Pharmacokinetics to the Intracellular Dynamic Phase — Direct Introduction of Nanoparticles into Cytoplasm of Living Cells

We developed a technology to directly introduce nanoparticles into the cytoplasm of living cells at one time without using a micromanipulator. Moreover, we confirmed that antisense oligonucleotides as a model drug can be released slowly in cytoplasm from these particles.

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来源期刊

2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)

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