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2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)最新文献

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Biological Transducers Based on Bacteriorhodopsin for Smart Biosensor Applications 基于细菌视紫红质的智能生物传感器
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.39
W. Wang, G. Knopf, A. Bassi
{"title":"Biological Transducers Based on Bacteriorhodopsin for Smart Biosensor Applications","authors":"W. Wang, G. Knopf, A. Bassi","doi":"10.1109/ICMENS.2004.39","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.39","url":null,"abstract":"In this study, a biological photoelectric transducer based on bacteriorhodopsin (bR) is described. Purple membrane (PM) containing bR are deposited on a TiO₂ electrode surface and electrically oriented. The dried bR purple membrane film is then utilized to investigate the photoelectric response. The latter is induced by charge displacement of bR molecules in the purple membranes. The response is affected by both the wavelength and intensity of the incident light sources. The experimental results indicate that the generated photo-voltage is proportional to the intensity of the illumination light, and the photo-voltage measured under different wavelengths correspond to the absorption spectrum of bR.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125894969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Lattice Boltzmann Simulations of Bubble Dynamics in Microchannels 微通道气泡动力学的晶格玻尔兹曼模拟
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.86
Junfeng Zhang, D. Kwok
{"title":"Lattice Boltzmann Simulations of Bubble Dynamics in Microchannels","authors":"Junfeng Zhang, D. Kwok","doi":"10.1109/ICMENS.2004.86","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.86","url":null,"abstract":"The moving contact line problem of liquid-vapor interfaces on solid surfaces was studied using a mean-field free-energy lattice Boltzmann method recently proposed [Zhang et al., Phys. Rev. E, 69, 032602, 2004]. We have examined the static and dynamic interfacial behaviors by means of the bubble and capillary wave tests and found that both the Laplace equation of capillarity and the dispersion relation were satisfied. Dynamic contact angles followed the general trend of contact line velocity observed experimentally and can be described by Blake's theory. The velocity fields near the interface were also obtained and are in good agreement with fluid mechanics and molecular dynamics studies. Our simulations demonstrated that incorporating interfacial effects into the lattice Boltzmann model can be a valuable and powerful alternative in interfacial studies.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122250436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cytotoxicity of Drug-Loaded Nanoparticles and Liposomes Carried by Aerosol "Cluster Bombs" in Lung Cancer Cells 气溶胶“集束炸弹”携带的载药纳米颗粒和脂质体在肺癌细胞中的细胞毒性
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.46
X. Tao, Hua Chen, Zhao-quan Wang, W. Finlay, R. Löbenberg, W. Roa
{"title":"Cytotoxicity of Drug-Loaded Nanoparticles and Liposomes Carried by Aerosol \"Cluster Bombs\" in Lung Cancer Cells","authors":"X. Tao, Hua Chen, Zhao-quan Wang, W. Finlay, R. Löbenberg, W. Roa","doi":"10.1109/ICMENS.2004.46","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.46","url":null,"abstract":"This study aims to identify the intracellular locations of nanoparticles and liposomes carried by aerosol \"cluster bomb\", and investigated the relative efficiencies of such drug delivery systems to kill cancer cells in vitro.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"160 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124891418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Finite Element-Based Analysis of Single-Crystal Si Contour-Mode Electromechanical RF Resonators 单晶硅等高线模机电射频谐振器的有限元分析
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.71
C. Maxey, S. Raman
{"title":"Finite Element-Based Analysis of Single-Crystal Si Contour-Mode Electromechanical RF Resonators","authors":"C. Maxey, S. Raman","doi":"10.1109/ICMENS.2004.71","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.71","url":null,"abstract":"Micron-scale electromechanical disk-shaped resonators have exhibited operational frequencies above 1 GHz and quality factors exceeding 1,500 at these frequencies. Additionally, such disk resonators can be potentially realized in current silicon CMOS and BiCMOS integrated circuit processes, making them attractive alternatives to traditional high-Q off-chip components. Accurate modeling of these devices is critical to predicting the mode-shape and, most importantly, the vibration frequency. This paper presents a finite element-based approach to modeling higher-order effects in disk-shaped resonators using ANSYS 7.0. An in-depth study of the mode-shapes for disk resonators of various sizes, and the effects of substrate anchors attached to the disks at various locations, is included. Effects on resonator operation due to metal layers, such as electroless plated copper, deposited on the disks are also simulated. All simulations are performed in a fully coupled electrical-mechanical environment so as to incorporate as many process and excitation variables as possible.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123738978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A Tunable RF MEMS Inductor 一种可调谐射频MEMS电感
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.24
I. Zine-El-Abidine, M. Okoniewski, J. McRory
{"title":"A Tunable RF MEMS Inductor","authors":"I. Zine-El-Abidine, M. Okoniewski, J. McRory","doi":"10.1109/ICMENS.2004.24","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.24","url":null,"abstract":"This paper reports a single-wafer micromachined radio-frequency (RF) inductor that can be integrated in a convetional RFIC device. The Inductor achieved a quality factor greater than 9 at 15 GHz and a self-resonance frequency well above 15 GHz. The inductor is tunable and the inductance variation is greater than 8%.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129296351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Developing and Testing of Drug Carrier Systems for Pulmonary Drug Delivery 肺给药药物载体系统的开发与测试
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.51
G. Borchard, M. Bivas-Benita, H. Junginger
{"title":"Developing and Testing of Drug Carrier Systems for Pulmonary Drug Delivery","authors":"G. Borchard, M. Bivas-Benita, H. Junginger","doi":"10.1109/ICMENS.2004.51","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.51","url":null,"abstract":"Pulmonary gene delivery is thought to play an important role in treating genetically related diseases and may induce immunity towards pathogens entering the body via the airways. We present here in vitro and in vivo methods developed at our laboratories to study carrier systems for pulmonary delivery of DNA vaccines.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128681613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
UV Nanoimprint Lithography Using an Elementwise Embossed Stamp 使用 Elementwise 压印印章进行紫外线纳米压印光刻技术
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.150
Jun‐ho Jeong, Y. Sim, H. Sohn, Eung-sug Lee
{"title":"UV Nanoimprint Lithography Using an Elementwise Embossed Stamp","authors":"Jun‐ho Jeong, Y. Sim, H. Sohn, Eung-sug Lee","doi":"10.1109/ICMENS.2004.150","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.150","url":null,"abstract":"Ultraviolet-nanoimprint lithography (UV-NIL) is a promising method for cost-effectively defining nanoscale structures at room temperature and low pressure. In an attempt to apply a large area stamp to UV-NIL in a low vacuum environment, we have proposed a new UV-NIL process using an element-wise embossed stamp (EES), which consists of a number of elements, each of which is separated by channels. Nano-scale patterns of each element were fabricated using e-beam lithography and an etching process in which a Cr film was employed as a hard mask for transferring nanostructures to a quartz plate. Before pressing the EES, low viscosity resin droplets with a nano-liter volume were dispensed on each element of the EES. Experiments on UV-NIL were performed on an EVG620-NIL. 380 nm - 1 µm features of the EES were successfully transferred to 4 in. wafers. We measured patterns and residual layers on the imprinted wafers to evaluate the potential of the proposed process. Experiments showed that the EES enables UV-NIL using a large-area stamp in a low vacuum environment.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128001680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Lipid/Polymer Nanoparticles as Tools to Improve the Therapeutic Activity of Existing and Emerging Anticancer Drug Combinations 脂质/聚合物纳米颗粒作为提高现有和新兴抗癌药物组合治疗活性的工具
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.88
E. Ramsay, D. Waterhouse, K. Gelmon, N. Santos, E. Wasan, Jehan Alnajim, M. Anantha, C. Tucker, R. Klasa, G. Bebb, Juliana Yeung, Karen Fang, L. Edwards, Yanping Hu, Corrina Warburton, V. Dragowska, Sheela A. Abraham, Gigi Chui, M. Bally
{"title":"Lipid/Polymer Nanoparticles as Tools to Improve the Therapeutic Activity of Existing and Emerging Anticancer Drug Combinations","authors":"E. Ramsay, D. Waterhouse, K. Gelmon, N. Santos, E. Wasan, Jehan Alnajim, M. Anantha, C. Tucker, R. Klasa, G. Bebb, Juliana Yeung, Karen Fang, L. Edwards, Yanping Hu, Corrina Warburton, V. Dragowska, Sheela A. Abraham, Gigi Chui, M. Bally","doi":"10.1109/ICMENS.2004.88","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.88","url":null,"abstract":"Cancer is a complex disease and virtually all chemotherapy regimens for treating cancer utilize drug combinations selected to affect several targets that contribute to cancer cell survival and disease progression. Although drug combinations are the standard of care for patients with advanced cancer, new anticancer drugs are typically first introduced in patients as single agents and only after many years of clinical trials are these single agents combined with other drugs to determine their optimal role in cancer treatment. This process needs to change if patients are going to receive the full benefit of the arsenal of approved cytotoxic/cytostatic agents and emerging molecularly targeted therapeutics. It is clear that drug delivery systems will play an important role in the development and use of drug combinations for the treatment of cancer and the objective of this discussion is to highlight how existing and emerging drug carriers can be used as an enabling technology to create fixed ratio anticancer drug combination products for the treatment of systemic disease.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122544604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental Measurements and Theoretical Estimation of Temperature in ECDM Process ECDM过程温度的实验测量与理论估计
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.63
A. V. Kulkarni, M. Karnik
{"title":"Experimental Measurements and Theoretical Estimation of Temperature in ECDM Process","authors":"A. V. Kulkarni, M. Karnik","doi":"10.1109/ICMENS.2004.63","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.63","url":null,"abstract":"Electrochemical discharge can be effectively and economically used for machining of a wide range of conducting and non-conducting materials, ceramics, and composites. This can be also used for selective deposition of metals and micro welding. Its potentials for rapid prototyping of small metallic parts have been vindicated. All these processes require generation of temperatures above the melting temperature of the metal under consideration. In the present work, experimentally measured and theoretically estimated temperature results are presented for electro chemical discharge machining (ECDM) process. In situ temperature measurements are performed for the first time in ECDM, especially, in the machining zone with various temperature sensing schemes. The temperatures at different radii of the work piece are calculated by considering the spark as a constant, circular heat source on the surface of the work piece and considering the heat balance of each discretised element of the work piece. Experimentally measured and theoretically estimated temperature results are comparable.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133385125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Finite Element Simulations of Transient Droplet Deformation in an Electrical Field 电场作用下液滴瞬态变形的有限元模拟
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.70
Graeme Supeene, C. Koch, S. Bhattacharjee
{"title":"Finite Element Simulations of Transient Droplet Deformation in an Electrical Field","authors":"Graeme Supeene, C. Koch, S. Bhattacharjee","doi":"10.1109/ICMENS.2004.70","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.70","url":null,"abstract":"Deformation of droplets in an externally imposed electrical field is a widely studied phenomenon, and is an important component of microfluidic operations involving electrical actuation of droplets. In this study, we explore a general numerical formulation for the deformation of droplets under an imposed electrical field. The solution is presented for two perfect dielectrics carring no free charge. The numerical solutions are first compared with an asymptotic analytic result for small deformations to assess the accuracy of the method. Following this, the dynamics of the deformation are presented to characterize the typical response times of droplets subjected to a step change in the electric field. The results provide the basis for modeling the dynamic response and control strategies for manipulating the droplets, and may provide considerable insight into microfluidic operations based on electrowetting.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125500340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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