2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)最新文献

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Nanofabrication of High Aspect Ratio Aerosol Particles for Deposition Studies in a Model Human Airway 高纵横比气溶胶颗粒的纳米制造及其在人体气道模型中的沉积研究
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.107
K. Gilbertson, W. Finlay, C. Lange, M. Brett, D. Vick
{"title":"Nanofabrication of High Aspect Ratio Aerosol Particles for Deposition Studies in a Model Human Airway","authors":"K. Gilbertson, W. Finlay, C. Lange, M. Brett, D. Vick","doi":"10.1109/ICMENS.2004.107","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.107","url":null,"abstract":"The ability to produce high aspect ratio particle aerosols (airborne fibres) is required in order to develop a thorough understanding of the parameters that affect the deposition of fibres in the mouth and throat. Such an ability is currently being developed. In this work, we produce monodisperse fibres from porous thin films by releasing small structures from a substrate. The development of a means to assay for these fibres is also discussed.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"196 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123274919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Improved Diagnosis and Monitoring of Cancer Using Portable Microfluidics Platforms 利用便携式微流体平台改进癌症诊断和监测
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.79
L. Pilarski, Sophia Adamia, P. Pilarski, R. Prakash, J. Lauzon, C. Backhouse
{"title":"Improved Diagnosis and Monitoring of Cancer Using Portable Microfluidics Platforms","authors":"L. Pilarski, Sophia Adamia, P. Pilarski, R. Prakash, J. Lauzon, C. Backhouse","doi":"10.1109/ICMENS.2004.79","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.79","url":null,"abstract":"Microfluidics chips offer the promise of fast and accurate diagnostic and monitoring tools that are inexpensive and automated. Tests that otherwise require expensive instrumentation and consume valuable reagents can be implemented on microfluidic chips for a fraction of the cost with dramatic improvement in speed. Minaturization offers multiple benefits, enabling multiple tests on one chip, requiring tiny tissue samples and fast reaction times for picoliter volumes. More complex microfluidics chips will be able to carry out sample processing followed by cell or molecule fractionation, molecular analysis and readout of the test result. Integrated platforms incorporating microfluidics offer portable testing devices for \"point of concern\" testing in health care facilities, in remote areas or in the home. These devices are likely to increase access to sophisticated testing within the health system while decreasing costs and improving the quality of care.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123153271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Delivery of Hydrophobic Drugs through Self-Assembling Nanostructures 通过自组装纳米结构递送疏水药物
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.47
G. Gaucher, E. Fournier, D. Garrec, M. Khalid, D. Hoarau, V. Sant, J. Leroux
{"title":"Delivery of Hydrophobic Drugs through Self-Assembling Nanostructures","authors":"G. Gaucher, E. Fournier, D. Garrec, M. Khalid, D. Hoarau, V. Sant, J. Leroux","doi":"10.1109/ICMENS.2004.47","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.47","url":null,"abstract":"Many potent therapeutic agents possess a high degree of hydrophobicity which can greatly impede their solubilization in aqueous media and thus hamper their oral or parenteral administration. In order to circumvent this limitation, novel drug delivery systems, such as polymeric micelles and lipid-based nanocapsules, are being developed. In general, these nano-sized carriers contain a hydrophobic core which provides the necessary environment to solubilize poorly water-soluble drugs. In addition, when administered intravenously, they can passively target inflamed or cancerous tissues due to the enhanced permeation and retention (EPR) effect, potentially improving the therapeutic efficacy of the drug while reducing its toxicity. Alternatively, the limited oral bioavailability of hydrophobic agents can be improved by selectively releasing the drug in its molecular form close to the absorption site. Polymeric micelles containing pH-sensitive moieties and loaded with a poorly water-soluble drug can dissociate and release their payload in the intestine. This presentation will focus on injectable polymeric and lipidic vectors for hydrophobic anti-cancer agents and on pH-sensitive polymeric micelles as promoters of the oral bioavailability of poorly water-soluble drugs [1].","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122651848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Surface Oriented Self Assembled Growth of Carbon Nanotubes 碳纳米管表面自组装生长研究
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.137
K. Sivakumar, B. Panchapakesan
{"title":"Surface Oriented Self Assembled Growth of Carbon Nanotubes","authors":"K. Sivakumar, B. Panchapakesan","doi":"10.1109/ICMENS.2004.137","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.137","url":null,"abstract":"We report the self assembled surface oriented growth of single walled carbon nanotubes along the surface of (100), (110) and (111) silicon wafers using thermal CVD. The nanotubes were grown using iron nanoparticles, 10 nm in diameter, as the catalyst. The growth was carried out at 1000oC in a methane atmosphere. The lattice matching of the silicon and iron crystal lattices led to the formation of self aligned silicides at a high temperature which helped orient the nanotubes. SEM, TEM and AFM characterization revealed single wall carbon nanotubes, about 10 nm in diameter and up to 10 μm in length, growing along the <111> direction of the silicon substrate. This process is easy, reliable and may enable the integration of nanotubes with CMOS processing technology.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124828092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
On the Design of an Electrohydrodynamic Ion-Drag Micropump 电流体动力离子拖动微泵的设计研究
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.119
M. Badran, M. Moussa
{"title":"On the Design of an Electrohydrodynamic Ion-Drag Micropump","authors":"M. Badran, M. Moussa","doi":"10.1109/ICMENS.2004.119","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.119","url":null,"abstract":"In this paper, several designs of an Electrohydrodynamic (EHD) Ion-Drag Micropump will be investigated. The goal is to determine the effect of several design parameters on the pressure-voltage relationship. The overall dimensions of the micropump channel are 500 µm x 480µm x 60µm. Four designs were tested in simulation with different combinations of the gap between the electrodes (S) and the gap between the electrode pairs (D) to examine their impact on the pumping performance. The design with small gap (S) and large gap (D) was found to have the best pumping performance.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125691751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
By-Pass Transition in Microchannels under EDL Effect EDL效应下微通道的旁路转换
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.40
S. Tardu
{"title":"By-Pass Transition in Microchannels under EDL Effect","authors":"S. Tardu","doi":"10.1109/ICMENS.2004.40","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.40","url":null,"abstract":"The effect of the electric double layer (EDL) on the bypass transition mechanism in the linear evolution stage is explored through direct numerical simulations. An initial perturbation velocity field consisting of a pair of counter-rotating vortices is introduced in Poiseuille and EDL flows and the time-space evolution of the perturbed field is analysed for short times at half the critical Reynolds numbers (3000 for Poiseuille and 300 for EDL). The wall normal and spanwise perturbation velocities development are both quantitatively and qualitatively similar in macro and micro flows. The streamwise velocity, which is initially zero and set up by the generation of the wall normal vorticity is twice larger under the EDL effect. Both flows develop inclined strong streamwise shear layers. Overall is the close similarity of the disturbance evolution showing that the three dimensional linear mechanism in EDL flow lead to the structures that are at least as strong as in Poiseuille flow.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134416089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rapid Performance Assessment Method for Microfluidic Chips 一种微流控芯片性能快速评估方法
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.21
Rubin Ma, K. Kaler, C. Backhouse
{"title":"A Rapid Performance Assessment Method for Microfluidic Chips","authors":"Rubin Ma, K. Kaler, C. Backhouse","doi":"10.1109/ICMENS.2004.21","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.21","url":null,"abstract":"We present a method to assess microchip performance for on-chip electrophoretic separations. The assessment is realized through electrophoretic manipulation of a DNA size standard using specially designed electric voltage programs. Results achieved from the assessment could be used as an indicator of microchip \"aging\" in terms of lowered resolutions and fluctuations in electro-osmotic flow (EOF).","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129723693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Conformations of Super-Elastic Carbon Micro/Nano-Springs and Their Properties 超弹性碳微/纳米弹簧的构象及其性能
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.45
Shaoming Yang, Xiuqin Chen, M. Hasegawa, S. Motojima
{"title":"Conformations of Super-Elastic Carbon Micro/Nano-Springs and Their Properties","authors":"Shaoming Yang, Xiuqin Chen, M. Hasegawa, S. Motojima","doi":"10.1109/ICMENS.2004.45","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.45","url":null,"abstract":"Double-helix carbon micro-springs were prepared by the Ni catalyzed pyrolysis of acetylene containing a small amount of H2S, in high purity (almost 100% among the deposits) and yield (about 20% versus acetylene feed). The conformation and some properties of the carbon micro-springs were examined, and the potential applications were discussed. It was found that they have super-elastic properties, and could be extended to 3-15 times of the original spring axis length and contracted to original state after the load was released. The resistivity increased with increasing extension length, and then got recovery after the load was released. This property enables the microsprings to be used as an advanced bulk sensor material in MEMS. Furthermore, the micro-springs exhibited outstanding electromagnetic wave absorption properties in GHz regions. The conformation of novel single-helix carbon nano-springs prepared by Fe-containing alloys as the catalyst will be also presented.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114826086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Dielectrophoretic Membrane Filtration Process by Integrating Microelectrode Array 集成微电极阵列的介电泳膜过滤过程
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.54
Shahnawaz Molla, S. Bhattacharjee, J. Masliyah
{"title":"Dielectrophoretic Membrane Filtration Process by Integrating Microelectrode Array","authors":"Shahnawaz Molla, S. Bhattacharjee, J. Masliyah","doi":"10.1109/ICMENS.2004.54","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.54","url":null,"abstract":"A coupled AC dielectrophoretic membrane filtration technique is proposed in this paper.This technique utilizes ACdielectrophoresis and preferential transport through a semi-permeable membrane. Simultaneous application of ACdielectrophoresis and membrane filtration can be used for separation of trace amounts of a target species from an emulsion. This can be achieved by embedding inter-digitated microelectrode arrays on a membrane surface used in a cross flow filtration system. The electrode array, when actuated by an AC signal, will create a dielectrophoretic force field to capture the target species onto the membrane surface from the flowing emulsion during cross flow filtration. This paper explains the theoretical principles underlying such a process, and describes a simple mathematical framework based on trajectory analysis for assessing the separation efficiency of the technique. Simulation results indicate that preferential transport of the emulsified water through themembrane in a cross flow filtration device can be significantly enhanced by incorporating an AC dielectrophoretic field in the process. The novel technique proposed here can lead to a highly efficient continuous separation process for dilute emulsions.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115937974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Recognition System Controlled by Thermosensitive Complexation Using Cyclodextrin-Conjugated Poly(ε-lysine)s 环糊精共轭聚(&#949;-赖氨酸)热敏络合控制的分子识别系统
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04) Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.102
A. Takahashi, H. Choi, T. Ooya, N. Yui
{"title":"Molecular Recognition System Controlled by Thermosensitive Complexation Using Cyclodextrin-Conjugated Poly(&#949;-lysine)s","authors":"A. Takahashi, H. Choi, T. Ooya, N. Yui","doi":"10.1109/ICMENS.2004.102","DOIUrl":"https://doi.org/10.1109/ICMENS.2004.102","url":null,"abstract":"Molecular recognition in chemistry and biology is a kind of host-guest phenomena, which concerns inclusion complexes formed through noncovalently controlled interactions between the host and guest. Possessing well-defined hydrophobic cavities of cyclodextrins (CDs), which can bind various organic, inorganic, and biological molecules to form stable inclusion complexes or supramolecular species, have been employed as excellent hosts in supramolecular chemistry and chiral selectors in separation science and technology. Hence, a great deal of efforts has been devoted to the design and syntheses of novel CD derivatives that display enhanced molecular binding abilities and selectivities for specific substrates.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114795983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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