FS ReportsPub Date : 2025-06-01DOI: 10.1016/j.xfre.2025.03.005
Evan J. Panken M.D. , Daniel R. Greenberg M.D. , Catherine S. Nam M.D. , Kathleen Hwang M.D. , Robert E. Brannigan M.D. , Joshua A. Halpern M.D., M.S.
{"title":"The use of immotile testicular sperm for in vitro fertilization/intracytoplasmic sperm injection: what are the outcomes?","authors":"Evan J. Panken M.D. , Daniel R. Greenberg M.D. , Catherine S. Nam M.D. , Kathleen Hwang M.D. , Robert E. Brannigan M.D. , Joshua A. Halpern M.D., M.S.","doi":"10.1016/j.xfre.2025.03.005","DOIUrl":"10.1016/j.xfre.2025.03.005","url":null,"abstract":"<div><div>Sperm extraction for in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) remains the only option for men with azoospermia to father biologic offspring. Even in cases of successful sperm retrieval, the challenge of selecting optimal sperm for use in IVF/ICSI is an area of research interest. Testicular sperm, unlike epididymal or ejaculated sperm, are often immotile, and there remains debate on the use of immotile testicular sperm in IVF/ICSI and how to best assess sperm viability. Therefore, we aimed to summarize the available literature regarding IVF/ICSI outcomes using immotile testicular sperm.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 2","pages":"Pages 108-115"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144312982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-06-01DOI: 10.1016/j.xfre.2025.02.008
Guido Mora Calderon M.D. , Fabiola D’Ambrosio M.D. , Alan Schwartz Ph.D. , Bert Scoccia M.D.
{"title":"Impact of race and ethnicity on in vitro fertilization outcomes in infertile women with polycystic ovary syndrome in the United States","authors":"Guido Mora Calderon M.D. , Fabiola D’Ambrosio M.D. , Alan Schwartz Ph.D. , Bert Scoccia M.D.","doi":"10.1016/j.xfre.2025.02.008","DOIUrl":"10.1016/j.xfre.2025.02.008","url":null,"abstract":"<div><h3>Objective</h3><div>To study the impact of maternal race and ethnicity on live birth rates (LBRs) in white, Asian, Hispanic, and African American women with infertility, with and without polycystic ovary syndrome (PCOS), undergoing in vitro fertilization (IVF) in the United States.</div></div><div><h3>Design</h3><div>Retrospective cohort study.</div></div><div><h3>Subjects</h3><div>We reviewed 256,018 patient records from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database, from 2014 to 2017, and 128,703 patients met our study inclusion criteria, who were women aged 21–40 years, undergoing their first nondonor fresh embryo transfer during IVF.</div></div><div><h3>Exposure</h3><div>Maternal race and ethnicity in women with PCOS.</div></div><div><h3>Main Outcome Measures</h3><div>Live birth rate.</div></div><div><h3>Results</h3><div>There were 21,866 women with infertility and PCOS and 106,837 women with infertility without PCOS. The LBR in the PCOS group was highest in white women (49.5%), compared with Hispanic (42.7%), Asian (41.6%), and African American (36%) women. The LBR in the non-PCOS group was highest in white women (45.1%), compared with Hispanic (40.5%), Asian (35.4%), and African American (34.3%) women. Logistic regression models were performed comparing women with PCOS vs. white women without PCOS as the referent group. The likelihood of having a live birth was significantly lower in African American and Asian women with PCOS. The likelihood of having a pregnancy loss was significantly higher in African American and Hispanic women with PCOS. In women who had a live birth, the likelihood of a neonatal death was significantly higher in Asian, Hispanic, and African American women in the PCOS group.</div></div><div><h3>Conclusion</h3><div>This is the largest IVF study to date assessing the impact of maternal race and ethnicity on live birth and neonatal death rates in women with infertility with and without PCOS. Our data suggest that there are significant racial and ethnic outcome disparities in women with infertility with and without PCOS undergoing IVF in the United States.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 2","pages":"Pages 168-175"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144312851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-06-01DOI: 10.1016/j.xfre.2025.05.003
Rebecca O’Connor J.D.
{"title":"Office of Public Affairs update: a quarterly update from the American Society for Reproductive Medicine Office of Public Affairs on key developments in reproductive health policy","authors":"Rebecca O’Connor J.D.","doi":"10.1016/j.xfre.2025.05.003","DOIUrl":"10.1016/j.xfre.2025.05.003","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 2","pages":"Page 107"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144312983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-06-01DOI: 10.1016/j.xfre.2025.03.010
Evan J. Panken M.D. , Joshua A. Halpern M.D., M.S.
{"title":"Is combined androgen and gonadotropin therapy a viable harm reduction strategy for men using high-dose exogenous androgens who are interested in family building?","authors":"Evan J. Panken M.D. , Joshua A. Halpern M.D., M.S.","doi":"10.1016/j.xfre.2025.03.010","DOIUrl":"10.1016/j.xfre.2025.03.010","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 2","pages":"Pages 127-128"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144313011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-06-01DOI: 10.1016/j.xfre.2025.04.010
{"title":"Reviewers of the Year 2024: F&S Reports celebrates excellence in our world-class reviewers","authors":"","doi":"10.1016/j.xfre.2025.04.010","DOIUrl":"10.1016/j.xfre.2025.04.010","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 2","pages":"Pages 103-104"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144312984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-06-01DOI: 10.1016/j.xfre.2025.04.001
Joseph Chervenak M.D., M.B.A.
{"title":"The state of financial support for fertility treatments in patients with cancer: a crucial aspect of improving access to care","authors":"Joseph Chervenak M.D., M.B.A.","doi":"10.1016/j.xfre.2025.04.001","DOIUrl":"10.1016/j.xfre.2025.04.001","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 2","pages":"Pages 199-200"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144312990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-04-01DOI: 10.1016/j.xfre.2024.12.006
Stephen Johnston B.Sc. Hons., Ph.D.
{"title":"Koala reproduction and the implications for human research","authors":"Stephen Johnston B.Sc. Hons., Ph.D.","doi":"10.1016/j.xfre.2024.12.006","DOIUrl":"10.1016/j.xfre.2024.12.006","url":null,"abstract":"<div><div>Wildlife species demonstrate a broad diversity of reproductive strategies that have allowed them to adapt and survive in their specific environments. The koala (<em>Phascolarctos cinereus</em>) is an iconic endangered Australian arboreal marsupial that demonstrates a unique form of mammalian reproduction but which on closer evaluation may provide fresh insight into our understanding of human reproduction and reproductive disease.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 ","pages":"Pages 13-18"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143828365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}