FS ReportsPub Date : 2026-08-01Epub Date: 2026-06-05DOI: 10.1016/j.xfre.2026.05.003
Zoe H. Pleasure Ph.D., M.P.H., Michelle A. Mengeling Ph.D., Ginny L. Ryan M.D., AM Racila Ph.D., Samantha K. Benson M.P.H., Siobhan S. Mahorter M.P.H., Anne G. Sadler Ph.D., Judy E. Stern Ph.D., Mark Vander Weg Ph.D., Lisa S. Callegari M.D., M.P.H.
{"title":"Associations between social and economic determinants of health and receiving infertility care among female Veterans: a cross-sectional study","authors":"Zoe H. Pleasure Ph.D., M.P.H., Michelle A. Mengeling Ph.D., Ginny L. Ryan M.D., AM Racila Ph.D., Samantha K. Benson M.P.H., Siobhan S. Mahorter M.P.H., Anne G. Sadler Ph.D., Judy E. Stern Ph.D., Mark Vander Weg Ph.D., Lisa S. Callegari M.D., M.P.H.","doi":"10.1016/j.xfre.2026.05.003","DOIUrl":"10.1016/j.xfre.2026.05.003","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the associations between social and economic determinants of health with receipt of infertility diagnoses and care among Veterans. In the non-Veteran population, socially and economically marginalized individuals are less likely to receive infertility care. Little is known about these associations in the population of United States military Veterans, who may have unique fertility care needs and healthcare access experiences.</div></div><div><h3>Design</h3><div>We analyzed cross-sectional survey data collected from the Impact of Sexual Assault and Combat-Related Trauma on Fertility in Veterans study conducted from 2016 to 2020.</div></div><div><h3>Subjects</h3><div>Our analytic sample includes the subset of Veterans aged 20–45 years who were assigned female sex at birth and experienced infertility, defined as a self-reported history of unprotected sex for 12 or more months without pregnancy.</div></div><div><h3>Exposure</h3><div>Variables of interest included social and economic determinants, including income, Veterans Health Administration (VA) benefits and insurance status, marital status, race and ethnicity, and sexual orientation.</div></div><div><h3>Main Outcome Measures</h3><div>Outcomes included self-reported receipt of an infertility diagnosis and fertility treatment. Associations between social and economic determinants and the outcomes were evaluated using multivariable logistic regression. Age and lifetime diagnoses of mental health conditions were included as potential confounders of these associations.</div></div><div><h3>Results</h3><div>Among the 589 female Veterans with self-reported infertility, 22.8% reported receiving an infertility diagnosis and 19.5% reported receiving fertility treatment. Having a household income of greater than $110,000 (odds ratio [OR] = 5.33, 95% confidence interval [CI], 2.06–13.77) was positively associated with receipt of an infertility diagnosis in adjusted models. Being married or currently living with a partner (OR = 2.32, 95% CI, 1.22–4.41) and having a household income of greater than $110,000 (OR = 3.89, 95% CI, 1.38–10.98) were positively associated with receiving fertility treatment in adjusted models. Neither race nor VA benefits and insurance status were associated with either outcome.</div></div><div><h3>Conclusion</h3><div>Similar to the non-Veteran population, income remains an important economic determinant of care receipt among Veterans. Our finding that only a minority of those with self-reported infertility received a diagnosis or treatment highlights the need for efforts to improve Veterans’ access to fertility care and thus their ability to achieve the families they desire.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 280-289"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-03-13DOI: 10.1016/j.xfre.2026.03.002
Sara G. Vargo B.S., Nicholas J. Thomas M.D., Katherine S. Brito M.D., Naghma A. Farooqi M.D., David Chia M.D.
{"title":"Delayed diagnosis and treatment of Sheehan syndrome: a case report","authors":"Sara G. Vargo B.S., Nicholas J. Thomas M.D., Katherine S. Brito M.D., Naghma A. Farooqi M.D., David Chia M.D.","doi":"10.1016/j.xfre.2026.03.002","DOIUrl":"10.1016/j.xfre.2026.03.002","url":null,"abstract":"<div><h3>Objective</h3><div>To report a case of Sheehan syndrome diagnosed and treated nearly 2 decades after a postpartum hemorrhage.</div></div><div><h3>Design</h3><div>Case report.</div></div><div><h3>Subjects</h3><div>A 45-year-old woman presenting with nonspecific symptoms found to have severe hyponatremia and panhypopituitarism 1 month after immigrating from China and 17 years after a postpartum hemorrhage.</div></div><div><h3>Exposure</h3><div>Hormone replacement with hydrocortisone, levothyroxine, and combined oral contraceptive pills.</div></div><div><h3>Main Outcome Measures</h3><div>Clinical and laboratory assessment of central adrenal insufficiency, hypothyroidism, and hypogonadotropic hypogonadism after initiation of treatment.</div></div><div><h3>Results</h3><div>After initiation of hydrocortisone and levothyroxine, the hyponatremia and nonspecific symptoms, including fatigue, dyspnea, nausea, vomiting, myalgias, and brain fog, improved rapidly. Pituitary magnetic resonance imaging demonstrated markedly reduced pituitary volume. Dual-energy x-ray absorptiometry scanning revealed osteopenia. The patient has had 9 months of treatment with cyclic combined oral contraceptive pills without hormonal withdrawal bleeding. Overall, she reports significant improvement in quality of life.</div></div><div><h3>Conclusion</h3><div>Postpartum hypopituitarism is widely underdiagnosed with nonspecific presentations and limited access to care contributing to diagnostic delay. Clinicians must maintain a high index of suspicion to diagnose hypopituitarism after a postpartum hemorrhage, even years after delivery. Early initiation of hormone replacement therapy is essential in patients with postpartum hypopituitarism for protection of cardiovascular and bone health.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 322-326"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-07-02DOI: 10.1016/j.xfre.2026.06.007
Marit Pearlman Shapiro M.D., M.P.H., Brian T. Nguyen M.D., M.Sc.
{"title":"Beyond use: lessons on contraceptive inequity from the National Survey of Family Growth","authors":"Marit Pearlman Shapiro M.D., M.P.H., Brian T. Nguyen M.D., M.Sc.","doi":"10.1016/j.xfre.2026.06.007","DOIUrl":"10.1016/j.xfre.2026.06.007","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 263-264"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-07-03DOI: 10.1016/j.xfre.2026.06.009
Richard J. Paulson M.D., M.S.
{"title":"Education vs. service in medical training: a false dichotomy that refuses to die","authors":"Richard J. Paulson M.D., M.S.","doi":"10.1016/j.xfre.2026.06.009","DOIUrl":"10.1016/j.xfre.2026.06.009","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Page 257"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-05-05DOI: 10.1016/j.xfre.2026.04.012
Timur K. Seckin B.S., Hakan Kula M.D., Tamer A. Seckin M.D.
{"title":"Artificial intelligence–augmented lesion recognition of peritoneal endometriosis: a novel technique","authors":"Timur K. Seckin B.S., Hakan Kula M.D., Tamer A. Seckin M.D.","doi":"10.1016/j.xfre.2026.04.012","DOIUrl":"10.1016/j.xfre.2026.04.012","url":null,"abstract":"<div><h3>Objective</h3><div>To describe a novel surgical approach for the detection and excision of peritoneal endometriosis using intraoperative Aqua Blue Contrast (ABC) with real-time AI-assisted detection.</div></div><div><h3>Design</h3><div>Case report describing a novel intraoperative surgical technique.</div></div><div><h3>Subjects</h3><div>A 28-year-old woman presenting with cardinal symptoms of endometriosis.</div></div><div><h3>Exposure</h3><div>Peritoneal endometriosis presents a significant diagnostic and surgical challenge due to the heterogeneity of lesion subtypes, including pigmented, occult, and microscopic forms. In this approach, intraoperative ABC was applied as a contrast-enhancing technique to improve visualization of the peritoneal surface. In parallel, AI-assisted lesion recognition was used as an adjunctive tool to augment intraoperative recognition of suspicious peritoneal areas. The technique enhances color differentiation, allowing identification of subtle peritoneal abnormalities that may not be easily visible under standard white-light laparoscopy.</div></div><div><h3>Main Outcome Measures</h3><div>Intraoperative visualization and identification of peritoneal endometriotic lesions.</div></div><div><h3>Results</h3><div>The ABC enhanced visual contrast between normal and abnormal peritoneal tissue, facilitating identification of occult lesions. The improved visualization with AI-assisted lesion recognition system supported more precise localization and excision of suspected endometriotic areas during surgery.</div></div><div><h3>Conclusion</h3><div>ABC with real time AI augmentation represents a promising intraoperative visualization technique for improving detection of peritoneal endometriosis. By enhancing lesion visibility, this approach may contribute to more accurate identification and more complete surgical excision.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Page 332"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-08-14DOI: 10.1016/j.xfre.2026.03.008
Florence Belva MD, PhD, Jean De Schepper MD, PhD, Christophe Blockeel MD, PhD
{"title":"Reply of the authors: “Do children born after embryo vitrification differ from siblings born after fresh embryo transfer?”","authors":"Florence Belva MD, PhD, Jean De Schepper MD, PhD, Christophe Blockeel MD, PhD","doi":"10.1016/j.xfre.2026.03.008","DOIUrl":"10.1016/j.xfre.2026.03.008","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 334-335"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-04-30DOI: 10.1016/j.xfre.2026.03.004
Sigal Klipstein M.D., Lauri A. Pasch Ph.D.
{"title":"Disclosing the use of donor gametes to donor-conceived children: best practices to support the family unit","authors":"Sigal Klipstein M.D., Lauri A. Pasch Ph.D.","doi":"10.1016/j.xfre.2026.03.004","DOIUrl":"10.1016/j.xfre.2026.03.004","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 260-262"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-06-30DOI: 10.1016/j.xfre.2026.06.004
Allison P. Watkins M.D., Bruce D. Pier M.D.
{"title":"Income over insurance: rethinking access to fertility care in veterans","authors":"Allison P. Watkins M.D., Bruce D. Pier M.D.","doi":"10.1016/j.xfre.2026.06.004","DOIUrl":"10.1016/j.xfre.2026.06.004","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 265-266"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2026-08-01Epub Date: 2026-08-14DOI: 10.1016/j.xfre.2026.06.002
Elizabeth L. Wolfe M.D., Lucas Bartl M.D., Heather Burks M.D., LaTasha B. Craig M.D., Jennifer D. Peck Ph.D., Karl R. Hansen M.D., Ph.D.
{"title":"Weight loss medication prescribing practices among fertility specialists: a cross-sectional survey study","authors":"Elizabeth L. Wolfe M.D., Lucas Bartl M.D., Heather Burks M.D., LaTasha B. Craig M.D., Jennifer D. Peck Ph.D., Karl R. Hansen M.D., Ph.D.","doi":"10.1016/j.xfre.2026.06.002","DOIUrl":"10.1016/j.xfre.2026.06.002","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 290-292"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diffuse testicular microlithiasis is associated with successful sperm retrieval in men with nonobstructive azoospermia","authors":"Yuji Tsuji M.D., Ph.D., Kazuma Nakano R.D.M.S., Shoichi Nariyoshi R.D.M.S., Noriko Abe R.N., M.W., Gen Sukegawa M.D.","doi":"10.1016/j.xfre.2026.06.001","DOIUrl":"10.1016/j.xfre.2026.06.001","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate whether ultrasonographic patterns of testicular microlithiasis are associated with sperm retrieval outcomes by microdissection testicular sperm extraction in men with nonobstructive azoospermia.</div></div><div><h3>Design</h3><div>Retrospective cohort study.</div></div><div><h3>Subjects</h3><div>A total of 975 men with histologically confirmed nonobstructive azoospermia who underwent microdissection testicular sperm extraction between July 2003 and September 2025 at two specialized male infertility clinics.</div></div><div><h3>Exposure</h3><div>Preoperative scrotal ultrasonography, with classification of testicular microlithiasis into four patterns: no microlithiasis, limited microlithiasis, classic microlithiasis, and diffuse microlithiasis characterized by a snowstorm appearance.</div></div><div><h3>Main Outcome Measures</h3><div>Successful sperm retrieval by microdissection testicular sperm extraction.</div></div><div><h3>Results</h3><div>Diffuse testicular microlithiasis characterized by a snowstorm appearance (n = 6) was associated with uniformly successful sperm retrieval. In contrast, limited and classic forms of testicular microlithiasis showed no independent association with sperm retrieval outcomes. Histological parameters, particularly Johnsen’s score, demonstrated the strongest association with successful sperm retrieval.</div></div><div><h3>Conclusions</h3><div>Diffuse testicular microlithiasis with a snowstorm appearance was associated with uniformly successful sperm retrieval by microdissection testicular sperm extraction in men with nonobstructive azoospermia, suggesting preserved focal spermatogenesis in this subgroup.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"7 4","pages":"Pages 293-300"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148718531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}