Theoretical and Natural Science最新文献_第3页

Overview of the habitability of exoplanets several factors of habitability 系外行星的可居住性概述可居住性的几个因素

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/43/20241097

Boya Zhang, Mengduo Wang, Xiaohang Xu

引用次数: 0

Unleashing the potential: Exploring the ubiquitin-proteasome system as a potential treatment for the Alzheimer's disease 释放潜能：探索泛素-蛋白酶体系统作为阿尔茨海默病潜在疗法的可能性

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/45/20240428

Wuji Yan, Jinfan Zhang

引用次数: 0

Unveiling the intricacies of the normal distribution: From theory to applications 揭开正态分布的神秘面纱：从理论到应用

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/36/20240617

Xingyu Ye

{"title":"Unveiling the intricacies of the normal distribution: From theory to applications","authors":"Xingyu Ye","doi":"10.54254/2753-8818/36/20240617","DOIUrl":"https://doi.org/10.54254/2753-8818/36/20240617","url":null,"abstract":"The normal distribution, also referred to as the Gaussian distribution, holds immense significance across multiple domains, from mathematics and physics to engineering and statistics. Beginning with its probabilistic foundations, the normal distribution is characterized by its bell-shaped curve, symmetric nature around the mean, and parameterization by the mean () and standard deviation (). Originating from the seminal works of Abraham de Moivre and further advanced by Gauss and Laplace, its theoretical underpinnings have significantly influenced statistical theory. Laplaces insights regarding errors and the normal distribution paved the way for its widespread adoption in statistical analysis. The normal distribution serves as a powerful tool in various applications, including estimating frequency distributions, analyzing student performance, establishing medical reference values, and forming the basis for numerous statistical methods. This paper explores the profound implications of the normal distribution, encompassing its definition, attributes, historical development, and practical applications, highlighting the enduring importance and versatility of the normal distribution in both theoretical and practical contexts.","PeriodicalId":341023,"journal":{"name":"Theoretical and Natural Science","volume":"42 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the expression of CG18269 under Zelda's regulation in early embryonic development of Drosophila melanogaster 探索 CG18269 在塞尔达调控下在黑腹果蝇早期胚胎发育中的表达

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/45/20240587

Yiwi Chen

引用次数: 0

Current status and future development of quantum computing 量子计算的现状和未来发展

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/36/20240606

Yingbin Jin

{"title":"Current status and future development of quantum computing","authors":"Yingbin Jin","doi":"10.54254/2753-8818/36/20240606","DOIUrl":"https://doi.org/10.54254/2753-8818/36/20240606","url":null,"abstract":"To overcome the scaling limitations of conventional semiconductor chips, quantum computing has emerged and experienced significant growth in recent years. Quantum computing utilizes resources such as quantum superposition and quantum entanglement to encode and process information. Compared to classical computing, this technology can provide exponential acceleration in the field of ultra-large-scale parallel computing. Consequently, its practical application is anticipated to have profound impacts on information and related technologies. The paper employs a comparative analysis approach to systematically examine the research progress of quantum computer technology. Specifically, the study emphasizes the analysis and consolidation of various quantum computing technology routes, critically evaluates their advantages and disadvantages, and provides a foresight into their future development trends. Currently, research on quantum computing technology is in its early stages and is evolving rapidly. Multiple technical paths are being pursued, resulting in a diverse and competitive landscape that is expected to persist in the short term, as it will take some time before the practical application of quantum computers becomes feasible.","PeriodicalId":341023,"journal":{"name":"Theoretical and Natural Science","volume":"34 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Specific application of nature-based solutions in ecological restoration 基于自然的解决方案在生态恢复中的具体应用

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/37/20240209

Minqian Liang

{"title":"Specific application of nature-based solutions in ecological restoration","authors":"Minqian Liang","doi":"10.54254/2753-8818/37/20240209","DOIUrl":"https://doi.org/10.54254/2753-8818/37/20240209","url":null,"abstract":"As a result of the growing human capacity to exploit and the rising and demand for natural resources, the earth is now experiencing ecological overload.Ecological restoration has emerged as a significant concern that human beings must confront. The notion of Nature-based Solutions introduced by the International Union for Conservation of Nature (IUCN) in 2004 has garnered increasing scholarly interest in recent years . As to the IUCN, nature-based solutions refer to measures that safeguard, responsibly oversee, and rehabilitate both natural and modified ecosystems. Since the concept of nature-based solution was put forward, numerous scholars have made various attempts to use it in the field of ecological restoration. Through the method of literature review, this paper elucidates the basic principles of ecological restoration and nature-based solutions. This research studies the specific implementation of nature-based solutions in ecological restoration, focusing on their specific application in water body and land restoration. Additionally, this paper summarizes the advancements made in this field of research and provides illustrative examples of nature-based solutions applied in ecological restoration.","PeriodicalId":341023,"journal":{"name":"Theoretical and Natural Science","volume":"22 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brief analysis of procedure in optogenetics 光遗传学程序简析

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/45/20240759

Zhaoxi Chen

{"title":"Brief analysis of procedure in optogenetics","authors":"Zhaoxi Chen","doi":"10.54254/2753-8818/45/20240759","DOIUrl":"https://doi.org/10.54254/2753-8818/45/20240759","url":null,"abstract":"This article aims to provide a brief analysis of the methods utilized in optogenetics data analysis procedure. The two main categories of procedure are online and offline analysis methods, which determines the causality of the system. Both approaches have their advantages and tradeoffs, and this article will introduce some examples of each procedure in an experimental setting, what are some specific processing methods they are using, what metrics are explained, how the two approaches performance compare, and how they produce and represent analytical data. One practical example on each approach, performed on a dataset from a previous experiment imaging neuronal activity in rats, is provided for better clarity and comparison measures. The offline example fits gaussian mixture model on high-pass filtered data, and the separate gaussian models are used to predict the status of the neuron given its relative fluorescence intensity. The online example uses an existing algorithm called OASIS, which uses an autoregressive model to reconstruct calcium trace and thus infers the spike. The main difference between the two is demonstrated to be their robustness and accuracy: online approach is more robust and can be utilized while recording the data, giving interpretable results with low latency, yet its accuracy does not depend on obtained sample number; offline approach is more time-consuming while fitting and training data to an optimal model. However, offline approaches accuracy will increase with large sample size. Both approaches provide deep insight into the acquired datasets, and while analyzing data they should be used strategically to fit the specific needs of the task.","PeriodicalId":341023,"journal":{"name":"Theoretical and Natural Science","volume":"14 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Applying the Markov chain in natural language processing and three-pool model 在自然语言处理和三池模型中应用马尔可夫链

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/36/20240593

Xunyang Wang, Yueheng Zhang

{"title":"Applying the Markov chain in natural language processing and three-pool model","authors":"Xunyang Wang, Yueheng Zhang","doi":"10.54254/2753-8818/36/20240593","DOIUrl":"https://doi.org/10.54254/2753-8818/36/20240593","url":null,"abstract":"This paper delves into the application of Markov chains in Natural Language Processing (NLP), and the Markov Chain Monte Carlo (MCMC) methodology relevant to the three-pool model. The former outlines the basic principles of Markov chains, highlighting their utility in predicting word sequences in language modelling and text generation, despite certain limitations. Also, the former describes mathematical frameworks like n-gram models that enhance prediction accuracy by considering multiple preceding words. It acknowledges challenges in NLP such as oversimplification and emotional depth, as well as computational issues in higher-order models. It concludes by discussing the integration of Markov chains with other models to mitigate these limitations, and their enduring relevance in computational linguistics. The later investigates the MCMC methodology, a seminal development in the field of statistical inference, which is especially useful when analysing complicated systems when traditional statistical techniques are inadequate. Moreover, this later explores the fundamental concepts of MCMC, clarifies how it is inherently related to Markov chains, presents the three-pool model that is commonly applied to models of physical, chemical, or ecological systems, and discusses how MCMC can be used to analyse these models.","PeriodicalId":341023,"journal":{"name":"Theoretical and Natural Science","volume":"15 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of FGF2 in stress-induced cFos expression FGF2 在应激诱导的 cFos 表达中的作用

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/44/20240828

Yifan Zhang

引用次数: 0

Potential applications of nanomaterials to treat skin photoaging 纳米材料治疗皮肤光老化的潜在应用

Theoretical and Natural Science Pub Date : 2024-07-26 DOI: 10.54254/2753-8818/45/20240584

Li Wang, Jiening Bao, Yinuo Li, Yifan Wang

{"title":"Potential applications of nanomaterials to treat skin photoaging","authors":"Li Wang, Jiening Bao, Yinuo Li, Yifan Wang","doi":"10.54254/2753-8818/45/20240584","DOIUrl":"https://doi.org/10.54254/2753-8818/45/20240584","url":null,"abstract":"Skin photoaging is a pathological condition induced by ultraviolet radiation. Among the three types of Ultraviolet radiation, UVA and UVB are the two that can penetrate the epidermis and induce various symptoms of skin photoaging. Symptoms include wrinkles, reduced skin thickness, inflammation, and skin cancers in the worst situations. Skin photoaging is multifactorial. Excessive reactive oxygen species (ROS) and dermal extracellular matrix (ECM) degradation are the two significant features of skin photoaging. Ultraviolet radiation also induces cellular senescence and apoptosis of several skin cells like keratinocytes, dermal fibroblasts, and immunosuppression. Topical administration of natural-derived and synthetic products and laser resurfacing therapies are currently used to treat skin photoaging. However, topical delivery of drugs has difficulty penetrating the epidermis, whereas laser treatments have relatively severe side effects. Nanomaterials, including nanoparticles and nanofibers, can encapsulate drugs to achieve a controlled topical drug release system with higher permeability and efficacy. Nanomaterials are biodegradable, non-toxic, and have high biocompatibility, making them potentially less invasive and having good side effect profiles when used in therapies. Thus, nanomaterials have the potential to be applied in treating skin photoaging, but the optimal doses, efficacy, and safety profiles require to be reconfirmed and improved in future studies.","PeriodicalId":341023,"journal":{"name":"Theoretical and Natural Science","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0