D.I. Udavliev, S. Engashev, E. Engasheva, A. S. Khlebalina, A. Lunegov
{"title":"Influence of a new β-lactam antibiotic on the behavior of experimental animals. Open field test results","authors":"D.I. Udavliev, S. Engashev, E. Engasheva, A. S. Khlebalina, A. Lunegov","doi":"10.52419/3006-2023-8-72-77","DOIUrl":"https://doi.org/10.52419/3006-2023-8-72-77","url":null,"abstract":"","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116361782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complex therapy of postpartum endometritis in cows using estrofantin","authors":"E. Finageev, T. Kuznetsova","doi":"10.52419/3006-2023-11-57-63","DOIUrl":"https://doi.org/10.52419/3006-2023-11-57-63","url":null,"abstract":"Postpartum endometritis is a common pathology in fresh cows, the morbidity of which can reach 50% or more. The causes of endometritis include retention of the placenta and, as a result, placentitis, atony of the uterus, infection of the birth canal, etc. 19 fresh cows were examined, 7 of them were diagnosed with postpartum endometritis. The drug Estrofantin, the active ingredient of which is prostaglandin F2α, was used in complex therapy with the drugs Uteroklin-T and Metrostim-Bel. Animals recovered on the 13th day from the start of therapy. This protocol for the treatment of endometritis in freshly calved cows is effective, allows us to maintain milk production and minimize the economic losses.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114808527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The influence of the experimental composition on some hematological parameters in zebrafish","authors":"V. Ponamarev","doi":"10.52419/3006-2023-11-41-44","DOIUrl":"https://doi.org/10.52419/3006-2023-11-41-44","url":null,"abstract":"At the moment, aqua and mariculture is experiencing a tremendous need for modern drugs for the pharmacocorrection of pathologies of non-infectious etiology, which are complex and have a universal integral pharmacological response. Determination of hepatoprotective properties was carried out according to the method described in step 4, however, the parity experimental group received the studied composition (combination of ursodeoxycholic and chenodeoxycholic acids in encapsulated form) at a dosage of 20 mg/kg (by the amount of bile acids). As a result of the study, no negative changes were noted in the experimental group, which indicates the hepatoprotective properties of the studied composition.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"911 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123926196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of the relationship of cholesterol production and ketogenesis in new calved cows","authors":"S. Vasileva","doi":"10.52419/3006-2023-11-17-22","DOIUrl":"https://doi.org/10.52419/3006-2023-11-17-22","url":null,"abstract":"This article describes the results of a study of cholesterol metabolism in new calved cows with different levels of beta-hydroxybutyric acid in the blood. It was found that activation of ketogenesis occurs in cows with increased (4,03±0,10 points) and low (3,33±0,07 points) fatness and is accompanied by a decrease in cholesterol biosynthesis. In cows with no hyperproduction of ketone bodies, the highest cholesterol growth rate is found - at all stages of the study, except for the initial level, this indicator significantly exceeds the values of the second group by 12,9 – 19,1% and the third group by 9,6 – 13,0%.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123171027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analogue of glucagon-like peptide-1 - properties, mechanisms of action, prospects for use","authors":"","doi":"10.52419/3006-2023-8-39-44","DOIUrl":"https://doi.org/10.52419/3006-2023-8-39-44","url":null,"abstract":"Glucagon-like peptide-1 is an isulin-like peptide hormone from the incretin family. It is secreted by L-cells of the mucous membrane of the ileum and colon, enhances insulin secretion and is a physiological regulator of appetite. The most popular pharmaceutical analogue of GLP-1 at the moment is liraglutide. Liraglutide also activates GLP-1 receptors, but is more stable and allows you to get a more powerful effect due to the prolongation of the drug. It is known that the action of liraglutide extends to all tissues with GLP-1 receptors, but now the drug is used only for correction of body weight and in the complex therapy of patients with type 2 diabetes mellitus. Thus, we have a drug with numerous and multidirectional effects, the full range of possibilities of which has not yet been explored. In this article, we analyze the possibilities of alternative use of this drug, based on literature data.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131445168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Etiology, pathogenesis and diagnosis of diabetes mellitus in cats","authors":"V. Bogomolova, E. F. Kasyanenko","doi":"10.52419/3006-2023-8-17-22","DOIUrl":"https://doi.org/10.52419/3006-2023-8-17-22","url":null,"abstract":"Cats suffer from type 2 diabetes more often. When observing 63 cats for 6 months, the most common signs were noted: polyuria, polydipsia, obesity and decreased activity. A common complaint from animal owners about the condition of the skin and coat. Cats have oily seborrhea, itching, scratching and hair loss on the back, near the root of the tail and on the stomach. The age of diabetic cats was 5-14 years. A biochemical blood test revealed an increase in glucose levels to 10-23.5 mmol / l (with a norm of up to 6.2). Almost all cats had an increase in hepatic transaminases by 2-3 or more times. It is important to carry out differential analyses, including the level of fructosamine in the blood serum (more than 365 mmol / l in diabetes), in order to exclude diabetes caused by stress. Timely early diagnosis, home and medical check of the dynamics of blood glucose levels will help to choose the optimal dose, frequency and course of insulin preparations, which will contribute to long-term remission.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121357341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}