{"title":"Some nuclear receptors as application points for drugs with hepatotropic activity","authors":"V. Ponamarev","doi":"10.52419/3006-2023-8-51-56","DOIUrl":"https://doi.org/10.52419/3006-2023-8-51-56","url":null,"abstract":"At present, one of the most promising directions in the search for chemical compounds-candidates for drugs is the fundamental study of signaling molecules, whose main function is to transmit information to the cell through ion channels and nuclear receptors associated with G-protein or with enzymatic activity. One of the fundamental tasks of modern pharmacology - the expansion of the range of hepatotropic drugs with a fundamentally new mechanism of action - is currently being actively solved, including through specific chemical compounds that act on cell nuclear receptors, one of which is obeticholic acid.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"70 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115671257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of the influence of the gene-diluent “cremello” on the inheritance of colors in the horses of the akhal-teke breed","authors":"T. Kuznetsova, E. Korochkina, D.E. Glavatskaya","doi":"10.52419/3006-2023-8-26-33","DOIUrl":"https://doi.org/10.52419/3006-2023-8-26-33","url":null,"abstract":"A wide palette of colors is one of the key features of the Akhal-Teke breed of horses. The phenotypic manifestation of a rare color is due to the influence of the “Cremello” clarifier gene on the synthesis of the main pigments - eumelanin and pheomelanin. In combination with the basic suits, it gives new rare suits – buckskin, palomino, cremello. The increased demand for foals with the clarifier gene stimulates interest in the topic of inheritance of colors. A study of the livestock of the Akhal-Teke breed of horses for the carriage of the “Cremello” diluent gene was carried out, crossbreeding schemes were proposed, and the percentage of the probability of the expected phenotype in the offspring was calculated. Analysis and phenotypic evaluation of the colors of the obtained foals showed that in order to obtain the colors of interest, it is necessary that at least one of the parents be of the Isabella color - the carrier of the Cremello gene in the homozygous state (CcrCcr).","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"225 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131493704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial enzyme systems as a cause for antibiotic affinity in bacteria","authors":"O. Popova","doi":"10.52419/3006-2023-11-53-56","DOIUrl":"https://doi.org/10.52419/3006-2023-11-53-56","url":null,"abstract":"The success of the use of antibiotic drugs is not in doubt. Despite the prepared base of regulatory documents, the use of antibiotics has a number of difficulties in their implementation and use in practice","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121677025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D.I. Udavliev, S. Engashev, E. Engasheva, A. S. Khlebalina, A. Lunegov
{"title":"Determination of the cumulative properties of the new drug Amoxiyantar","authors":"D.I. Udavliev, S. Engashev, E. Engasheva, A. S. Khlebalina, A. Lunegov","doi":"10.52419/3006-2023-8-78-81","DOIUrl":"https://doi.org/10.52419/3006-2023-8-78-81","url":null,"abstract":"The article presents data on the cumulative properties of the drug Amoxiantar on laboratory outbred mice. The cumulation coefficient was 0.5. From this it follows that the drug Amoxianatr has cumulative properties.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129320560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacological effects of taxifolin (dihydroquercitin).","authors":"O. Popova","doi":"10.52419/3006-2023-8-68-71","DOIUrl":"https://doi.org/10.52419/3006-2023-8-68-71","url":null,"abstract":"Summary. Currently, native drugs are increasingly being used as an alternative to allopathic drugs. The article discusses the main regularities in the pharmacology of taxifolin, studied both at the Department of Pharmacology and Toxicology of the Federal State Budgetary Educational Institution of Higher Education, St. Petersburg State University of Medicine, and on the basis of literary sources of international databases.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126348548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Presentation in higher school: opportunities and prospects","authors":"O. Popova","doi":"10.52419/3006-2023-11-49-52","DOIUrl":"https://doi.org/10.52419/3006-2023-11-49-52","url":null,"abstract":"The first step in any presentation is understanding your audience. This 52 will affect your choice of content as well as the presentation format. So, for students of the 3rd and 5th year, the same topic will be presented in different ways. This is influenced by the age and experience of the students (skills that the student has mastered during clinical practice, the disciplines that the student has mastered, etc.)","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114337724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extra-focal osteosynthesis of a comminuted fracture of the lower jaw in a dog after a car injury","authors":"V.V. Zemlyanaya","doi":"10.52419/3006-2023-8-23-25","DOIUrl":"https://doi.org/10.52419/3006-2023-8-23-25","url":null,"abstract":"To date, among the injuries found in small pets, a special place from the position of veterinary surgery is occupied by car injuries. Very often they are the cause of jaw fractures and require competent surgical intervention. Extra–focal osteosynthesis is one of the types of osteosynthesis that is used in such patients","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130598302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The epizootic situation of fish aeromonosis in the Krasnodar region, the prospects for the prevention and elimination of infectious fish diseases in the region","authors":"A. V. Basankin, V. Basankina, M. Semenenko","doi":"10.52419/3006-2023-8-7-13","DOIUrl":"https://doi.org/10.52419/3006-2023-8-7-13","url":null,"abstract":"results of monitoring the epizootic situation in fish farms and enterprises of the Krasnodar region, prospects for the prevention and elimination of infectious diseases of fish.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116118147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of purulent-catarrhal endometritis in cows on the farm of the Leningrad region","authors":"E. Finageev, T. Kuznetsova","doi":"10.52419/3006-2023-8-82-86","DOIUrl":"https://doi.org/10.52419/3006-2023-8-82-86","url":null,"abstract":"Fertility disorders in dairy cows are associated with postpartum infections. Up to 30% of new-bodied cows may have inflammation of the endometrium of the uterus for various reasons. In case of contamination of the uterus, various microflora are identified – bacteria, viruses, fungi, etc. 19 cows were examined in the postpartum period and 21.1% of the animals were diagnosed with purulent–catarrhal endometritis on the 3rd - 5th day. Treatment: after the novocaine blockade, an Enroflon tablet was injected into the uterine cavity, and Metrostim-Bel was additionally used. Cows with delayed afterbirth, without signs of endometritis, were treated with the drug \"Uteraton\". The proposed treatment regimen resulted in a satisfactory condition of the animals and can be recommended for introduction into production.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122636405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Veterinary communication skills: student perceptions","authors":"N. L. Korotkova","doi":"10.52419/3006-2023-11-23-27","DOIUrl":"https://doi.org/10.52419/3006-2023-11-23-27","url":null,"abstract":"The article is devoted to the characteristics of communication in veterinary clinical practice. It is concluded that it is necessary to develop communicative competence in the process of professional training as one of the most important professional competencies of a future veterinary doctor.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116848185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}