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Nanoparticles as a transport system for corvacrol compounds 纳米颗粒作为一种运输系统的克罗酚类化合物
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-8-64-67
O. Popova
{"title":"Nanoparticles as a transport system for corvacrol compounds","authors":"O. Popova","doi":"10.52419/3006-2023-8-64-67","DOIUrl":"https://doi.org/10.52419/3006-2023-8-64-67","url":null,"abstract":"Colloidal delivery systems, including microencapsulation and nanotechnology, are promising approaches in pharmacology. We have used liposomes to deliver systems containing Corvacrol and assessed the promise of liposomal agents for solving major problems in drug pharmacokinetics.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122997744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the parameters of a clinical blood test in rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect 使用降糖药增强保肝药物的大鼠临床血液试验参数的变化
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-11-28-34
P. Pogodaeva
{"title":"Changes in the parameters of a clinical blood test in rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect","authors":"P. Pogodaeva","doi":"10.52419/3006-2023-11-28-34","DOIUrl":"https://doi.org/10.52419/3006-2023-11-28-34","url":null,"abstract":"Glucagon-like peptide-1 is an isulin-like peptide hormone from the incretin family. The most popular pharmaceutical analogue of GLP-1 at the moment is liraglutide. GLP-1 receptors are localized in many areas of the brain responsible for the regulation of metabolic processes and eating behavior and in specific areas of the pancreas, heart, blood vessels, immune system, skin and adipose tissue, gastrointestinal tract and kidneys. We can definitely say that the effect of liraglutide extends to all tissues equipped with GLP-1 receptors, while the effect of the drug on the cardiovascular system, immune system, kidneys and gastrointestinal tract is still being studied. Also interesting is the possible effect of liraglutide on the liver, as an organ directly related to lipid and carbohydrate metabolism. In this article, we analyze the possibilities of using Saxenda, the main active ingredient of which is liraglutide, to potentiate the hepatoprotective effects of the Hepaton-vet drug in groups of rats with induced hepatopathy, evaluating the effect of these drugs on the parameters of a clinical blood test.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114938363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypoglycemic drugs in pharmacocorrection and pathologies of the hepatobiliary system 降糖药在药物矫正和肝胆系统病理中的应用
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-8-45-50
P. Pogodaeva, L. Karpenko
{"title":"Hypoglycemic drugs in pharmacocorrection and pathologies of the hepatobiliary system","authors":"P. Pogodaeva, L. Karpenko","doi":"10.52419/3006-2023-8-45-50","DOIUrl":"https://doi.org/10.52419/3006-2023-8-45-50","url":null,"abstract":"","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129732141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacological correction of recurrent cat cystitis with the drug "uro- wax" “无蜡”药物治疗复发性猫膀胱炎
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-8-34-38
K. A. Pogodaeva, P. D. Bokhan
{"title":"Pharmacological correction of recurrent cat cystitis with the drug \"uro- wax\"","authors":"K. A. Pogodaeva, P. D. Bokhan","doi":"10.52419/3006-2023-8-34-38","DOIUrl":"https://doi.org/10.52419/3006-2023-8-34-38","url":null,"abstract":"","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126885594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the biochemical parameters of the blood of rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect 使用降糖药增强保肝药物对大鼠血液生化参数的影响
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-11-35-40
P. Pogodaeva
{"title":"Changes in the biochemical parameters of the blood of rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect","authors":"P. Pogodaeva","doi":"10.52419/3006-2023-11-35-40","DOIUrl":"https://doi.org/10.52419/3006-2023-11-35-40","url":null,"abstract":"An interesting and unexplored to date is the hepatoprotective effect of hypoglycemic drugs, analogues of glucagon-like peptide-1, which include liraglutide. Knowing the positive effect of liraglutide on plasma lipid fractions and a general decrease in adipose tissue, a decrease in glucagon production and an increase in insulin synthesis, a beneficial effect on the cardiovascular system and an anti-inflammatory effect, there is reason to believe that this drug may be useful in the complex therapy of liver diseases, such as fatty hepatosis, cirrhosis and non-infectious hepatitis, as its action affects the pathogenetic links of this group of diseases. 40 In this article, we analyze the possibilities of using Saxenda, the main active ingredient of which is liraglutide, to potentiate the hepatoprotective effects of the Hepaton-vet drug in groups of rats with induced hepatopathy, evaluating the effect of these drugs on blood biochemical parameters.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130573648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of alcohol on cognitive functions of rats 酒精对大鼠认知功能的影响
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-11-4-8
D.S. Almakaeva
{"title":"Effect of alcohol on cognitive functions of rats","authors":"D.S. Almakaeva","doi":"10.52419/3006-2023-11-4-8","DOIUrl":"https://doi.org/10.52419/3006-2023-11-4-8","url":null,"abstract":"The effect of alcohol on the cognitive abilities of laboratory rats was studied. Individuals systematically received small doses of alcohol for a long time (4 months). Throughout the study, the results of the cognitive functions of animals were recorded, namely the ability to navigate in space and motor activity. At 1 month of alcohol intake, the cognitive abilities of the studied individuals improved significantly, but by the end of the experiment, the experimental subjects showed significantly lower results, thereby revealing the negative effects of alcohol on the body.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131891807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacoecological state of the habitat of aqua and mariculture objects 水产养殖对象生境的药物生态状况
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-8-57-63
V. Ponamarev
{"title":"Pharmacoecological state of the habitat of aqua and mariculture objects","authors":"V. Ponamarev","doi":"10.52419/3006-2023-8-57-63","DOIUrl":"https://doi.org/10.52419/3006-2023-8-57-63","url":null,"abstract":"In recent years, an increasing number of studies have been published in the scientific literature on the problem of the adverse effects of residues of pharmaceutical substances in the habitat of aquatic and mariculture objects. The identification of pharmacological compounds, including their by-products of transformation, is still an open question, which determines the need to expand current scientific research to assess the impact of pharmaceuticals, their metabolites and transformation products on the aquatic environment.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132894590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enucleation of the eyeball in chronic glaucoma in cats. 猫慢性青光眼的眼球摘除术。
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-8-14-16
E. S. Bogatyreva
{"title":"Enucleation of the eyeball in chronic glaucoma in cats.","authors":"E. S. Bogatyreva","doi":"10.52419/3006-2023-8-14-16","DOIUrl":"https://doi.org/10.52419/3006-2023-8-14-16","url":null,"abstract":"Glaucoma is a fairly common disease among small pets. There are various methods of treatment, however, with a chronic course of the disease and ineffective use of medications, resort to removing the eyeball.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115431720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of splenectomy in the treatment of spleen neoplasia in rats 脾切除术在大鼠脾肿瘤治疗中的应用
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-8-4-6
M.A. Ageikina
{"title":"The use of splenectomy in the treatment of spleen neoplasia in rats","authors":"M.A. Ageikina","doi":"10.52419/3006-2023-8-4-6","DOIUrl":"https://doi.org/10.52419/3006-2023-8-4-6","url":null,"abstract":"To date, a significant percentage of surgical interventions account for abdominal operations in small pets. At the same time, the problem of the prevalence of neoplasms in decorative rats is relevant. Splenectomy is one of the most effective methods of treating neoplasia for them. It is recommended to undergo a medical examination every six months, since splenomegaly is noticed only when the organ is enlarged during a visual diagnostic examination.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124905053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ASSOCIATION OF LIVER PATHOLOGIES WITH THE CONTAMINATION OF THE GASTROINTESTINAL TRACT WITH H.PYLORI 肝脏病变与胃肠道幽门螺杆菌污染的关系
SPbVetScience : collection of scientific papers Pub Date : 1900-01-01 DOI: 10.52419/3006-2023-11-9-16
A.S. Atikov
{"title":"THE ASSOCIATION OF LIVER PATHOLOGIES WITH THE CONTAMINATION OF THE GASTROINTESTINAL TRACT WITH H.PYLORI","authors":"A.S. Atikov","doi":"10.52419/3006-2023-11-9-16","DOIUrl":"https://doi.org/10.52419/3006-2023-11-9-16","url":null,"abstract":"Currently, one of the most promising areas in bacteriology is the study of the bacterium Helicobacter pylori. New studies show a link between H. pylori and some liver diseases, but their exact mechanisms and connections are still not fully understood. Despite this, studies of H. pylori and its association with liver diseases remain relevant to this day. This article presents an analysis of the association of H. Pylori with liver diseases.","PeriodicalId":338753,"journal":{"name":"SPbVetScience : collection of scientific papers","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114679755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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