Changes in the parameters of a clinical blood test in rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect

Glucagon-like peptide-1 is an isulin-like peptide hormone from the incretin family. The most popular pharmaceutical analogue of GLP-1 at the moment is liraglutide. GLP-1 receptors are localized in many areas of the brain responsible for the regulation of metabolic processes and eating behavior and in specific areas of the pancreas, heart, blood vessels, immune system, skin and adipose tissue, gastrointestinal tract and kidneys. We can definitely say that the effect of liraglutide extends to all tissues equipped with GLP-1 receptors, while the effect of the drug on the cardiovascular system, immune system, kidneys and gastrointestinal tract is still being studied. Also interesting is the possible effect of liraglutide on the liver, as an organ directly related to lipid and carbohydrate metabolism. In this article, we analyze the possibilities of using Saxenda, the main active ingredient of which is liraglutide, to potentiate the hepatoprotective effects of the Hepaton-vet drug in groups of rats with induced hepatopathy, evaluating the effect of these drugs on the parameters of a clinical blood test.