Fujita Medical Journal最新文献

{"title":"Development and preliminary evaluation of a tele-rehabilitation exercise system using computer-generated animation.","authors":"Nobuhiro Kumazawa,&nbsp;Soichiro Koyama,&nbsp;Masahiko Mukaino,&nbsp;Kazuhiro Tsuchiyama,&nbsp;Tsuyoshi Tatemoto,&nbsp;Hiroki Tanikawa,&nbsp;Kei Ohtsuka,&nbsp;Masaki Katoh,&nbsp;Yohei Otaka,&nbsp;Eiichi Saitoh,&nbsp;Shigeo Tanabe","doi":"10.20407/fmj.2021-020","DOIUrl":"https://doi.org/10.20407/fmj.2021-020","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the safety and acceptability of a newly developed tele-rehabilitation exercise system using computer-generated animation.</p><p><strong>Methods: </strong>The participants comprised a convenience sample of 38 diverse individuals in Experiment 1 (15 healthy young people, 16 healthy older people, 5 patients with stroke, and 2 patients with respiratory disease) and 18 healthy older individuals in Experiment 2. Experiment 1 assessed safety in terms of cardiopulmonary vascular aspects and risk of fall, and Experiment 2 assessed treatment acceptability via a subjective evaluation. All participants completed the same exercise program. The safety assessment was conducted using heart rate (HR) and saturation of percutaneous oxygen (SpO2), measured before and after exercise. In addition, the occurrence of falls was assessed. For the acceptability assessment, the participants answered five questions (three-point Likert scale) after the exercise program.</p><p><strong>Results: </strong>The safety assessment indicated that HR and SpO2 changed from 70.5±10.2 beats per minute and 97.8±1.3% before exercise to 87.6±13.6 beats per minute and 98.2±0.9% after exercise, respectively. In addition, all participants completed the exercises without experiencing any falls. In the acceptability assessment, the score reflecting continuation desire was the highest of the five items examined (2.71±0.46). In contrast, the adequacy of exercise intensity had the lowest score (1.29±0.57).</p><p><strong>Conclusions: </strong>The present system was confirmed to be safe, and the participants were motivated to continue the exercises. Future developments should incorporate a function to enable participants and medical staff to adjust exercise intensity according to individual physical function.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 4","pages":"114-120"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40479903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of initial empirical antimicrobial choice and cause of in-hospital death in patients with nursing and healthcare-associated pneumonia (NHCAP): A retrospective study.","authors":"Kenichi Kato,&nbsp;Kazunobu Kuwabara,&nbsp;Kiyotaka Ono,&nbsp;Yusuke Kito,&nbsp;Tatsuyoshi Yokoi,&nbsp;Takazumi Yoshida,&nbsp;Keisuke Kato,&nbsp;Masahiro Hirose,&nbsp;Daijo Inaguma,&nbsp;Takahiko Horiguchi","doi":"10.20407/fmj.2021-019","DOIUrl":"https://doi.org/10.20407/fmj.2021-019","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the differences in antimicrobial selection outcomes in nursing and healthcare-associated pneumonia (NHCAP) patients with and without risk factors for drug-resistant pathogen (RDRP) infection, and to identify the cause of in-hospital death after improvement of NHCAP.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of the medical records of hospitalized adult patients with NHCAP. NHCAP patients were divided into the RDRP and non-RDRP groups. The RDRP group was further classified into the narrow and broad subgroups according to the type of empirical antimicrobial agent selected. The difference in mortality between these subgroups was then examined. The cause of all in-hospital deaths was also evaluated.</p><p><strong>Results: </strong>e evaluated 220 patients with NHCAP. There was no difference in mortality between the narrow and broad subgroups (11.8% vs. 15.4%, p=0.655). Among the group with improved NHCAP, 11.3% (n=23/203) died in hospital before discharge. Although the causes of death in patients who improved after NHCAP were diverse, the most common was recurrence of pneumonia.</p><p><strong>Conclusions: </strong>Empirical antimicrobial therapy for NHCAP may not always require selection of broad-spectrum antimicrobial agents, as has been previously reported. Patients with NHCAP may die from other causes, even after NHCAP has improved.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 4","pages":"127-133"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40479907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between long-term alcohol consumption and insomnia symptoms in civil servants: Aichi Workers' Cohort Study.","authors":"Motoi Terabe,&nbsp;Tsuyoshi Kitajima,&nbsp;Atsuhiko Ota,&nbsp;Hiroshi Yatsuya,&nbsp;Nakao Iwata","doi":"10.20407/fmj.2021-015","DOIUrl":"https://doi.org/10.20407/fmj.2021-015","url":null,"abstract":"<p><strong>Objectives: </strong>The influence of habitual alcohol consumption on insomnia symptoms in healthy workers remains unclear. In this study, we evaluated the association between habitual alcohol consumption among civil servants and insomnia symptoms such as difficulty falling asleep, difficulty staying asleep, and tiredness after sleep, using longitudinal data.</p><p><strong>Methods: </strong>We enrolled civil servants in a prospective cohort study who completed questionnaires at baseline. Of those, 2861 participants were revaluated in a 5-year follow-up survey. Insomnia symptoms during the past month were assessed using self-reporting. Alcohol drinking habits were assessed by querying the frequency of drinking alcohol as well as the amount of alcohol usually consumed per one occasion.</p><p><strong>Results: </strong>Drinking alcohol every day was less likely to have difficulty falling asleep (odds ratio, 0.42 95% confidence interval, 0.20-0.89), and drinking alcohol 3 or more days a week was associated with difficulty staying asleep (odds ratio, 1.48; 95% confidence interval, 1.16-1.90).</p><p><strong>Conclusions: </strong>Drinking alcohol every day may produce subjective improvement in sleep onset. However, drinking alcohol 3 or more days a week may increase arousal during sleep, which contributes to reduced sleep quality. These results suggest the possibility that long-term daily habitual drinking may reinforce a sense of improvement in subjective sleep onset but may possibly induce sleep disturbance.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 4","pages":"103-107"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40490741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of moderation on rubric criteria for inter-rater reliability in an objective structured clinical examination with real patients.","authors":"Tetsuro Watari, Soichiro Koyama, Yusaku Kato, Yonho Paku, Yoshikiyo Kanada, Hiroaki Sakurai","doi":"10.20407/fmj.2021-010","DOIUrl":"10.20407/fmj.2021-010","url":null,"abstract":"<p><p>Objectives: Objective structured clinical examinations (OSCEs) are used to assess clinical competence in medical education. Evaluations using video-recorded OSCEs are effective in reducing costs in terms of time and human resources. To improve inter-rater reliability, these evaluations undergo moderation in the form of a discussion between the raters to obtain consistency in grading according to the rubric criteria. We examined the effect of moderation related to the rubric criteria on the inter-rater reliability of a video-recorded OSCE with real patients.</p><p><strong>Methods: </strong>Forty OSCE videos in which students performed range-of-motion tests at shoulder abduction on real patients were assessed by two raters. The two raters scored videos 1 to 10 without moderation and videos 11 to 40 with moderation each time. The inter-rater reliability of the OSCE was calculated using the weighted kappa coefficient.</p><p><strong>Results: </strong>The mean scores of the weighted kappa coefficients were 0.49 for videos 1 to 10, 0.57 for videos 11 to 20, 0.66 for videos 21 to 30, and 0.82 for videos 31 to 40.</p><p><strong>Conclusions: </strong>An assessment of video-recorded OSCEs was conducted with real patients in a real clinical setting. Repeated moderation improved the inter-rater reliability. This study suggests the effectiveness of moderation in OSCEs with real patients.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 3","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40685092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of vacuum-assisted closure after stoma closure with purse string suturing: a retrospective trial.","authors":"Koji Masumori,&nbsp;Kotaro Maeda,&nbsp;Tsunekazu Hanai,&nbsp;Harunobu Sato,&nbsp;Yoshikazu Koide,&nbsp;Hiroshi Matsuoka,&nbsp;Hidetoshi Katsuno,&nbsp;Tomoyoshi Endo,&nbsp;Yeongcheol Cheong,&nbsp;Ichiro Uyama","doi":"10.20407/fmj.2021-007","DOIUrl":"https://doi.org/10.20407/fmj.2021-007","url":null,"abstract":"<p><strong>Objectives: </strong>Surgical site infection (SSI) is a problematic complication after stoma closure. The purse string suture (PSS) technique eliminates this problem, but the area takes longer to heal. The present retrospective study was performed to evaluate the usefulness of a vacuum-assisted closure (VAC) system for the promotion of wound healing after stoma closure.</p><p><strong>Methods: </strong>Consecutive patients undergoing stoma closure with the PSS technique were divided into two groups: those treated with and without use of the VAC system. The volume of dead space and the size of the wound were measured after stoma closure in both groups. The same measurements were performed on days 3 and 7 after closure. The time needed for wound closure was also examined in both groups. Outcomes were also evaluated according to age, body mass index, operative time, bleeding volume, wound consistency, patient satisfaction, perioperative inflammatory response, occurrence of SSI, and hospitalization days.</p><p><strong>Results: </strong>The VAC group comprised 31 patients, and the non-VAC group comprised 34 patients. The volume of dead space on days 3 and 7 after closure was significantly smaller in the VAC group than in the non-VAC group (P=0.006 and P<0.001, respectively). The number of SSIs was significantly lower in the VAC group than in the non-VAC group (P=0.014).</p><p><strong>Conclusion: </strong>The dead space volume on days 3 and 7 after stoma closure with PSS significantly decreased by using the VAC system. The incidence of SSI after stoma closure also significantly decreased by using the VAC system.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 3","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40685090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of the menthol test as a clinical evaluation method for oxaliplatin-induced neuropathy.","authors":"Yeongcheol Cheong,&nbsp;Hidetoshi Katsuno,&nbsp;Hiroshi Matsuoka,&nbsp;Masahiro Mizuno,&nbsp;Tomoyoshi Endo,&nbsp;Tadahiro Kamiya,&nbsp;Yosuke Tajima,&nbsp;Keigo Ashida,&nbsp;Yoshikazu Koide,&nbsp;Koji Masumori,&nbsp;Harunobu Sato,&nbsp;Tsunekazu Hanai,&nbsp;Kotaro Maeda,&nbsp;Ichiro Uyama,&nbsp;Junichiro Hiro,&nbsp;Koichi Suda","doi":"10.20407/fmj.2021-011","DOIUrl":"https://doi.org/10.20407/fmj.2021-011","url":null,"abstract":"<p><strong>Objectives: </strong>To determine whether the tongue menthol test, which measures the cold sensation detection threshold (CDT) of the tongue, used before and after oxaliplatin administration is an objective evaluation method for oxaliplatin-induced peripheral neuropathy (OPN).</p><p><strong>Methods: </strong>The tongue menthol test was administered to patients both before and after undergoing chemotherapy containing oxaliplatin for colorectal cancer. The tongue menthol test was conducted by applying a menthol solution (a selective agonist of transient receptor potential cation channel subfamily M member 8 [TRPM8]) to the tongue and measuring the CDT.</p><p><strong>Results: </strong>The mean CDT before the first dose of oxaliplatin was 0.34% (0.005%-1%; <i>n</i>=38), and the mean CDT after the first dose was 0.32% (0.005%-1%; <i>n</i>=38). The CDT appeared to decrease after the first dose, but this difference was not significant. In patients who received five courses of oxaliplatin, changes in CDT values were compared before and after the five courses. In patients with Neurotoxicity Criteria of Debiopharm (DEB-NTC) grade 2 neuropathy, the pre-oxaliplatin administration CDT was compared between before grade exacerbation and when exacerbation occurred, and was found to decline when grade exacerbation occurred. Moreover, when the CDTs before and after administration were compared before grade exacerbation, there was a significant decrease in CDT after administration (<i>P</i>=0.04).</p><p><strong>Conclusions: </strong>By performing a menthol test in oxaliplatin-treated patients, it may be possible to objectively predict the exacerbation of peripheral neuropathy at an early stage.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 3","pages":"88-95"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40685093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse reactions to mRNA coronavirus disease 2019 (COVID-19) vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 576 medical staff.","authors":"Masamichi Hayashi,&nbsp;Sayako Morikawa,&nbsp;Yusuke Goto,&nbsp;Takazumi Yoshida,&nbsp;Yutaro Kimura,&nbsp;Kazuyoshi Imaizumi","doi":"10.20407/fmj.2021-009","DOIUrl":"https://doi.org/10.20407/fmj.2021-009","url":null,"abstract":"<p><strong>Objectives: </strong>Various measures have been taken to curb the COVID-19 epidemic, but their effect has been limited. Vaccines are expected to make a definite improvement. In Japan, vaccination began in February 2021. However, there are very few reports of adverse reactions to mRNA vaccines for the new coronavirus (SARS-CoV-2) in Japanese people. Therefore, adverse reactions in 576 vaccinated medical staff at the author's hospital were investigated.</p><p><strong>Methods: </strong>The subjects were 576 medical staff who wished to receive the new coronavirus (SARS-CoV-2) vaccine. The first vaccination was performed with Pfizer's new coronavirus mRNA vaccine (commercial name: Comirnaty intramuscular injection) from March 8 to March 15, 2021. The second vaccination was performed from March 29 to April 5, 2021, at an interval of more than 21 days from the first vaccination.</p><p><strong>Results: </strong>Adverse reactions were seen in six subjects in the first vaccination. There was dyspnea in one subject, arthralgia in one subject, fever/malaise in three subjects, and left axillary pain and lymphadenopathy in one subject. One subject had a reaction at the vaccination site that needed to be addressed. At the second vaccination, adverse reactions were observed in 64 subjects. There was fever in 58 subjects, malaise in 21 subjects, arthralgia in 12 subjects, aching pain in 11 subjects, headache in six subjects, chills in six subjects, nausea in three subjects, redness in two subjects, dizziness in two subjects, hives in two subjects, swelling in two subjects, cough in one subject, and itching in one subject (some had multiple adverse reactions). Fever was observed in the range of body temperature from 37.4 to 38.9 degrees.</p><p><strong>Conclusions: </strong>Most of the adverse reactions to the COVID-19 vaccine were mild, and no serious anaphylaxis was observed. Vaccination was considered perfectly feasible if attention is paid to adverse reactions.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 3","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40684205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal study of the vaginal microbiome in pregnancies involving preterm labor.","authors":"Yoshiko Sakabe,&nbsp;Haruki Nishizawa,&nbsp;Asuka Kato,&nbsp;Yoshiteru Noda,&nbsp;Akiko Ohwaki,&nbsp;Hikari Yoshizawa,&nbsp;Takema Kato,&nbsp;Takao Sekiya,&nbsp;Takuma Fujii,&nbsp;Hiroki Kurahashi","doi":"10.20407/fmj.2021-017","DOIUrl":"https://doi.org/10.20407/fmj.2021-017","url":null,"abstract":"<p><strong>Objectives: </strong>Alterations in the vaginal bacterial flora reflect the status of various obstetric conditions and are associated with mechanisms that underlie certain pregnancy-associated complications. These changes are also a predictive biomarker for clinical outcomes of these adverse events.</p><p><strong>Methods: </strong>We examined the vaginal microbiome in samples from pregnant Japanese women with preterm labor.</p><p><strong>Results: </strong>The microbiota composition in preterm delivery (PD) samples differed from those of control or threatened preterm delivery (TPD) samples in principal component analysis. An increase in Firmicutes and a decrease in Actinobacteria were significantly associated with PD only (both <i>P</i><0.01). In the Firmicutes phylum, <i>Lactobacillus</i> tended to be abundant, and the abundance of <i>L. iners</i> and <i>L. crispatus</i> was especially high, whereas the <i>L. gasseri</i> population was low in PD samples. Longitudinal analysis showed that the abundance of <i>L. iners</i> decreased after commencing tocolytic treatment in TPD samples compared with before treatment, but it remained high in PD samples.</p><p><strong>Conclusions: </strong>The vaginal microbiome may be a useful prognostic indicator of preterm labor and a monitoring tool for tocolytic treatment to prevent preterm birth.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 3","pages":"96-101"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40685091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delays in initial workflow cause delayed initiation of mechanical thrombectomy in patients with in-hospital ischemic stroke.","authors":"Kenichiro Suyama,&nbsp;Shoji Matsumoto,&nbsp;Ichiro Nakahara,&nbsp;Yoshio Suyama,&nbsp;Jun Morioka,&nbsp;Akiko Hasebe,&nbsp;Jun Tanabe,&nbsp;Sadayoshi Watanabe,&nbsp;Kiyonori Kuwahara,&nbsp;Yuichi Hirose","doi":"10.20407/fmj.2021-014","DOIUrl":"https://doi.org/10.20407/fmj.2021-014","url":null,"abstract":"<p><strong>Objectives: </strong>The benefit of mechanical thrombectomy for acute ischemic stroke is highly time dependent. However, time to treatment is longer for in-hospital stroke patients than community-onset stroke patients. This study aimed to clarify the cause of this difference.</p><p><strong>Methods: </strong>A retrospective single-center study was performed to analyze patients with large vessel occlusion who underwent mechanical thrombectomy between January 2017 and December 2019. Patients were divided into in-hospital stroke and community-onset stroke groups. Clinical characteristics and treatment time intervals were compared between groups.</p><p><strong>Results: </strong>One hundred four patients were analyzed: 17 with in-hospital stroke and 87 with community-onset stroke. Patient characteristics did not significantly differ between groups. Median door (stroke recognition)-to-computed tomography time (36 min vs. 14 min, P<0.01) and door-to-puncture time (135 min vs. 117 min, P=0.02) were significantly longer in the in-hospital stroke group than the community-onset stroke group. However, median computed tomography-to-puncture time (104 min vs. 104 min, P=0.47) and puncture-to-reperfusion time (53 min vs. 38 min, P=0.17) did not significantly differ.</p><p><strong>Conclusions: </strong>Longer door-to-puncture time in in-hospital stroke patients was mostly caused by longer door-to-computed tomography time, which is the initial part of the workflow. An in-hospital stroke protocol that places importance on early stroke specialist consultation and prompt transportation to the computed tomography scanner might hasten treatment and improve outcomes in patients with in-hospital stroke.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 3","pages":"73-78"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40685094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seasonal variation in the prevalence of Gram-negative bacilli in sputum and urine specimens from outpatients and inpatients.","authors":"Yusuke Kito,&nbsp;Kazunobu Kuwabara,&nbsp;Kiyotaka Ono,&nbsp;Kenichi Kato,&nbsp;Tatsuyoshi Yokoi,&nbsp;Kohki Horiguchi,&nbsp;Keisuke Kato,&nbsp;Masahiro Hirose,&nbsp;Tomomi Ohara,&nbsp;Kenta Goto,&nbsp;Yumi Nakamura,&nbsp;Yoshikatsu Koike,&nbsp;Takahiko Horiguchi","doi":"10.20407/fmj.2021-003","DOIUrl":"https://doi.org/10.20407/fmj.2021-003","url":null,"abstract":"<p><strong>Objectives: </strong>To determine whether the prevalence of gram-negative bacilli (GNB; <i>Pseudomonas aeruginosa</i>, <i>Klebsiella pneumoniae</i>, and <i>Escherichia coli</i>) in sputum and urine specimens from outpatients and inpatients differed by season and according to temperature and humidity changes.</p><p><strong>Methods: </strong>In this retrospective study, microbiologic data for adult patients from 2008 to 2019 were retrieved from the electronic database of a hospital in Japan. Data were categorized by specimen type (sputum and urine) and specimen collection (outpatient and inpatient). Associations between variables were assessed using Spearman's rank correlation coefficients. Differences between groups were assessed using Pearson's chi-square test and analysis of discrete variance.</p><p><strong>Results: </strong>Among inpatients, the frequencies of <i>P. aeruginosa</i> and <i>K. pneumoniae</i> isolation from sputum specimens were higher in summer and autumn. The frequency of <i>P. aeruginosa</i> isolation from urine specimens was higher in autumn. These seasonal trends were observed in specimens from both outpatients and inpatients. No seasonal trend was observed in the frequency of <i>E. coli</i> isolation. Mean monthly temperature was positively correlated with the frequency of isolating <i>P. aeruginosa</i> (r=0.2198, p=0.0081) and <i>K. pneumonia</i>e (r=0.3443, p=0.00002) from sputum as well as with the frequency of isolating <i>K. pneumoniae</i> (r=0.1905, p=0.0222) from urine. Mean monthly humidity was positively correlated with the frequency of isolating <i>K. pneumoniae</i> (r=0.2602, p=0.0016) from sputum.</p><p><strong>Conclusions: </strong>GNB were isolated more frequently in summer and autumn than in other seasons. These seasonal trends were observed for both outpatient and inpatient specimens. Seasonality should be considered for optimal infection control of GNB in hospitals.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"8 2","pages":"46-51"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10241153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}